Org pitching register -- Inter-league
Regular season -- as of 10/28/2006
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| David Aardsma | ChN | mr | 24 | 6.17 | 1 | 1 | 0 | 30 | 0 | 0 | 0 | 42.1 | 43 | 29 | 29 | 23 | 36 | 11 | 2 |
| Winston Abreu | Bal | mr | 29 | 5.74 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 15.2 | 23 | 11 | 10 | 11 | 8 | 4 | 1 |
| Jeremy Accardo |   | mr | 24 | 2.78 | 1 | 2 | 0 | 35 | 0 | 0 | 0 | 55.0 | 42 | 17 | 17 | 20 | 52 | 2 | 2 |
| Jon Adkins | SD | mr | 28 | 3.20 | 8 | 2 | 0 | 49 | 0 | 0 | 0 | 78.2 | 74 | 31 | 28 | 23 | 45 | 5 | 10 |
| Jeremy Affeldt* |   | mr | 27 | 4.73 | 6 | 5 | 0 | 56 | 9 | 0 | 0 | 116.0 | 117 | 67 | 61 | 51 | 60 | 17 | 16 |
| Matt Albers | Hou | sp | 23 | 3.00 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 12.0 | 7 | 4 | 4 | 7 | 10 | 1 | 1 |
| Antonio Alfonseca | Tex | mr | 34 | 4.15 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.2 | 10 | 4 | 4 | 4 | 4 | 1 | 0 |
| Steve Andrade | KC | mr | 28 | 18.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 2 | 2 | 1 | 0 | 0 | 0 |
| Greg Aquino | Ari | mr | 28 | 4.59 | 0 | 1 | 0 | 47 | 0 | 0 | 0 | 86.1 | 93 | 47 | 44 | 41 | 88 | 14 | 8 |
| Tony Armas | Was | sp | 28 | 4.95 | 9 | 10 | 0 | 32 | 30 | 0 | 0 | 149.0 | 167 | 83 | 82 | 54 | 111 | 21 | 13 |
| Bronson Arroyo | Cin | sp | 29 | 3.38 | 19 | 6 | 0 | 36 | 35 | 6 | 0 | 242.2 | 198 | 102 | 91 | 77 | 185 | 31 | 21 |
| Miguel Asencio | Col | mr | 25 | 11.25 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4.0 | 9 | 6 | 5 | 4 | 1 | 1 | 0 |
| Ezequiel Astacio | Hou | mr | 26 | 11.57 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 5 | 5 | 3 | 1 | 3 | 1 | 0 |
| Pedro Astacio | Was | sp | 36 | 5.72 | 5 | 6 | 0 | 18 | 17 | 0 | 0 | 89.2 | 120 | 64 | 57 | 31 | 37 | 16 | 7 |
| Brandon Backe | Hou | sp | 28 | 6.69 | 0 | 4 | 0 | 8 | 8 | 0 | 0 | 37.2 | 48 | 29 | 28 | 19 | 19 | 2 | 1 |
| Cha Seung Baek | Sea | sp | 26 | 5.10 | 3 | 1 | 0 | 6 | 6 | 0 | 0 | 30.0 | 32 | 18 | 17 | 13 | 19 | 7 | 3 |
| Danys Baez |   | mr | 28 | 3.95 | 5 | 3 | 1 | 58 | 0 | 0 | 0 | 70.2 | 71 | 34 | 31 | 19 | 48 | 7 | 2 |
| Jeff Bajenaru | Ari | mr | 28 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 1 | 0 | 0 | 4 | 1 | 0 | 0 |
| Scott Baker | Min | sp | 24 | 6.15 | 3 | 7 | 0 | 16 | 16 | 0 | 0 | 74.2 | 99 | 56 | 51 | 19 | 56 | 14 | 1 |
| Brian Bannister | NYN | sp | 25 | 7.07 | 0 | 3 | 0 | 6 | 6 | 0 | 0 | 28.0 | 24 | 22 | 22 | 19 | 17 | 4 | 2 |
| Kevin Barry | Atl | mr | 27 | 5.40 | 1 | 1 | 0 | 14 | 1 | 0 | 0 | 20.0 | 28 | 16 | 12 | 12 | 10 | 1 | 2 |
| Miguel Batista | Ari | sp | 35 | 6.15 | 10 | 15 | 0 | 34 | 33 | 1 | 0 | 158.0 | 208 | 120 | 108 | 65 | 84 | 22 | 15 |
| Rick Bauer | Tex | mr | 29 | 2.26 | 6 | 1 | 1 | 56 | 1 | 0 | 0 | 95.2 | 84 | 27 | 24 | 31 | 41 | 4 | 10 |
| Denny Bautista |   | mr | 23 | 6.99 | 5 | 3 | 0 | 9 | 8 | 0 | 0 | 37.1 | 49 | 30 | 29 | 13 | 20 | 6 | 1 |
| Jonah Bayliss | Pit | mr | 25 | 4.25 | 2 | 1 | 0 | 19 | 0 | 0 | 0 | 29.2 | 26 | 15 | 14 | 21 | 33 | 0 | 2 |
| T.J. Beam | NYA | mr | 25 | 6.57 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 12.1 | 20 | 14 | 9 | 4 | 11 | 6 | 1 |
| Josh Beckett | Bos | sp | 26 | 3.82 | 12 | 10 | 0 | 33 | 33 | 2 | 1 | 197.2 | 181 | 87 | 84 | 58 | 148 | 32 | 20 |
| Erik Bedard* | Bal | sp | 27 | 3.96 | 10 | 7 | 0 | 33 | 33 | 1 | 0 | 188.2 | 204 | 90 | 83 | 73 | 173 | 20 | 18 |
| Joe Beimel* | LAN | mr | 29 | 6.48 | 9 | 6 | 2 | 74 | 0 | 0 | 0 | 76.1 | 93 | 58 | 55 | 42 | 32 | 15 | 14 |
| Matt Belisle | Cin | mr | 26 | 2.32 | 8 | 0 | 2 | 36 | 2 | 0 | 0 | 62.0 | 61 | 24 | 16 | 27 | 29 | 6 | 11 |
| Heath Bell | NYN | mr | 28 | 7.67 | 0 | 1 | 4 | 21 | 0 | 0 | 0 | 29.1 | 53 | 27 | 25 | 10 | 21 | 8 | 4 |
| Armando Benitez | SF | cl | 33 | 5.43 | 2 | 6 | 20 | 55 | 0 | 0 | 0 | 61.1 | 79 | 38 | 37 | 28 | 50 | 10 | 2 |
| Joaquin Benoit | Tex | mr | 28 | 3.79 | 3 | 3 | 0 | 53 | 0 | 0 | 0 | 90.1 | 84 | 46 | 38 | 37 | 94 | 11 | 4 |
| Kris Benson | Bal | sp | 31 | 5.01 | 9 | 11 | 0 | 30 | 30 | 1 | 0 | 170.2 | 175 | 105 | 95 | 59 | 85 | 30 | 11 |
| Jason Bergmann | Was | mr | 24 | 4.92 | 5 | 5 | 0 | 33 | 6 | 0 | 0 | 78.2 | 82 | 54 | 43 | 29 | 62 | 13 | 6 |
| Adam Bernero |   | sp | 29 | 4.30 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 14.2 | 16 | 7 | 7 | 3 | 14 | 3 | 0 |
| Rafael Betancourt | Cle | mr | 31 | 1.86 | 4 | 5 | 5 | 60 | 0 | 0 | 0 | 87.0 | 68 | 20 | 18 | 9 | 66 | 6 | 4 |
| Chad Billingsley | LAN | sp | 21 | 4.05 | 3 | 5 | 0 | 16 | 16 | 0 | 0 | 91.0 | 84 | 43 | 41 | 58 | 61 | 10 | 9 |
| Kurt Birkins* | Bal | mr | 25 | 1.51 | 3 | 2 | 1 | 33 | 0 | 0 | 0 | 41.2 | 23 | 11 | 7 | 18 | 37 | 2 | 3 |
| Joe Blanton | Oak | sp | 25 | 3.46 | 12 | 8 | 0 | 31 | 31 | 3 | 2 | 192.1 | 199 | 86 | 74 | 56 | 118 | 9 | 21 |
| Jeremy Bonderman | Det | sp | 23 | 3.76 | 15 | 9 | 0 | 34 | 34 | 5 | 2 | 213.0 | 214 | 98 | 89 | 54 | 189 | 17 | 22 |
| Boof Bonser | Min | sp | 24 | 5.42 | 5 | 9 | 0 | 18 | 18 | 0 | 0 | 96.1 | 120 | 61 | 58 | 18 | 77 | 25 | 16 |
| Chris Booker |   | mr | 29 | 4.00 | 1 | 3 | 1 | 13 | 0 | 0 | 0 | 18.0 | 14 | 8 | 8 | 2 | 9 | 3 | 0 |
| Chris Bootcheck | LAA | mr | 27 | 9.37 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 16.1 | 22 | 21 | 17 | 15 | 16 | 5 | 1 |
| Dave Borkowski | Hou | mr | 29 | 4.08 | 3 | 2 | 4 | 54 | 0 | 0 | 0 | 108.0 | 113 | 51 | 49 | 28 | 84 | 13 | 8 |
| Joe Borowski | Flo | cl | 35 | 3.42 | 6 | 7 | 24 | 71 | 0 | 0 | 0 | 84.1 | 90 | 41 | 32 | 32 | 73 | 4 | 3 |
| Micah Bowie* | Was | mr | 31 | 0.57 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 15.2 | 13 | 1 | 1 | 9 | 5 | 0 | 0 |
| Chad Bradford | NYN | mr | 31 | 1.85 | 4 | 2 | 1 | 39 | 0 | 0 | 0 | 68.0 | 61 | 17 | 14 | 10 | 56 | 1 | 12 |
| Ryan Braun | KC | mr | 25 | 7.36 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 7.1 | 11 | 6 | 6 | 4 | 6 | 1 | 1 |
| Bill Bray* |   | mr | 23 | 5.08 | 3 | 4 | 1 | 53 | 0 | 0 | 0 | 56.2 | 67 | 38 | 32 | 27 | 44 | 5 | 9 |
| Dewon Brazelton | SD | mr | 26 | 7.04 | 1 | 0 | 0 | 5 | 2 | 0 | 0 | 15.1 | 22 | 12 | 12 | 7 | 8 | 6 | 0 |
| Craig Breslow* | Bos | mr | 25 | 3.68 | 1 | 0 | 1 | 6 | 0 | 0 | 0 | 7.1 | 6 | 6 | 3 | 5 | 5 | 0 | 1 |
| Eude Brito* | Phi | mr | 27 | 12.60 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 5.0 | 11 | 7 | 7 | 6 | 5 | 1 | 0 |
| Chris Britton | Bal | mr | 23 | 3.46 | 1 | 3 | 1 | 37 | 0 | 0 | 0 | 52.0 | 52 | 23 | 20 | 13 | 39 | 5 | 3 |
| Doug Brocail | SD | mr | 39 | 3.14 | 0 | 0 | 1 | 11 | 0 | 0 | 0 | 14.1 | 15 | 9 | 5 | 7 | 8 | 0 | 0 |
| Jim Brower |   | mr | 33 | 11.15 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 15.1 | 30 | 27 | 19 | 13 | 5 | 2 | 2 |
| Andrew Brown | Cle | mr | 25 | 2.18 | 1 | 0 | 1 | 21 | 0 | 0 | 0 | 20.2 | 18 | 6 | 5 | 11 | 11 | 2 | 3 |
| Jonathan Broxton | LAN | mr | 22 | 4.46 | 5 | 7 | 3 | 74 | 0 | 0 | 0 | 84.2 | 76 | 44 | 42 | 27 | 115 | 16 | 4 |
| Brian Bruney | NYA | mr | 24 | 9.35 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.2 | 9 | 9 | 9 | 12 | 12 | 0 | 1 |
| Taylor Buchholz | Hou | sp | 24 | 6.14 | 6 | 11 | 0 | 20 | 19 | 0 | 0 | 99.2 | 113 | 70 | 68 | 30 | 54 | 24 | 10 |
| Mark Buehrle* | ChA | sp | 27 | 5.37 | 9 | 12 | 0 | 32 | 32 | 0 | 0 | 174.1 | 232 | 114 | 104 | 53 | 90 | 31 | 15 |
| Ambiorix Burgos | KC | cl | 22 | 6.79 | 4 | 13 | 3 | 79 | 1 | 0 | 0 | 102.0 | 116 | 79 | 77 | 56 | 91 | 24 | 12 |
| A.J. Burnett | Tor | sp | 29 | 5.71 | 9 | 7 | 0 | 21 | 21 | 0 | 0 | 110.1 | 145 | 76 | 70 | 40 | 85 | 14 | 14 |
| Mike Burns |   | mr | 27 | 13.78 | 0 | 1 | 1 | 14 | 0 | 0 | 0 | 16.1 | 45 | 28 | 25 | 9 | 10 | 3 | 2 |
| Brian Burres* | Bal | mr | 25 | 5.40 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.1 | 3 | 2 | 2 | 1 | 1 | 0 | 0 |
| Dave Bush | Mil | sp | 26 | 4.23 | 12 | 12 | 0 | 32 | 32 | 5 | 1 | 215.0 | 199 | 111 | 101 | 39 | 182 | 38 | 13 |
| Paul Byrd | Cle | sp | 35 | 3.64 | 15 | 8 | 0 | 31 | 31 | 3 | 1 | 190.1 | 218 | 93 | 77 | 34 | 79 | 27 | 12 |
| Tim Byrdak* | Bal | mr | 32 | 14.46 | 0 | 0 | 1 | 9 | 0 | 0 | 0 | 9.1 | 21 | 19 | 15 | 14 | 6 | 3 | 5 |
| Daniel Cabrera | Bal | sp | 25 | 4.51 | 10 | 9 | 0 | 26 | 26 | 1 | 1 | 141.2 | 118 | 79 | 71 | 93 | 138 | 11 | 22 |
| Fernando Cabrera | Cle | mr | 24 | 6.21 | 3 | 2 | 0 | 43 | 0 | 0 | 0 | 66.2 | 71 | 49 | 46 | 33 | 77 | 18 | 5 |
| Matt Cain | SF | sp | 21 | 3.40 | 16 | 7 | 1 | 33 | 31 | 1 | 1 | 196.0 | 151 | 76 | 74 | 78 | 193 | 13 | 11 |
| Kiko Calero | Oak | mr | 31 | 3.36 | 3 | 8 | 2 | 67 | 0 | 0 | 0 | 72.1 | 77 | 29 | 27 | 32 | 86 | 9 | 9 |
| Shawn Camp | Tam | mr | 30 | 8.84 | 3 | 2 | 0 | 63 | 0 | 0 | 0 | 91.2 | 163 | 98 | 90 | 28 | 59 | 10 | 21 |
| Jose Capellan | Mil | mr | 25 | 4.14 | 1 | 2 | 0 | 47 | 0 | 0 | 0 | 78.1 | 71 | 36 | 36 | 29 | 65 | 13 | 1 |
| Matt Capps | Pit | mr | 22 | 2.58 | 7 | 3 | 0 | 75 | 0 | 0 | 0 | 115.0 | 98 | 36 | 33 | 14 | 87 | 7 | 17 |
| Chris Capuano* | Mil | sp | 27 | 3.93 | 14 | 12 | 0 | 34 | 34 | 1 | 0 | 222.1 | 241 | 112 | 97 | 51 | 172 | 28 | 20 |
| Fausto Carmona | Cle | mr | 22 | 6.29 | 2 | 4 | 0 | 34 | 7 | 0 | 0 | 68.2 | 92 | 53 | 48 | 21 | 48 | 8 | 9 |
| Chris Carpenter | StL | sp | 31 | 4.03 | 14 | 10 | 0 | 32 | 32 | 6 | 4 | 205.1 | 207 | 97 | 92 | 43 | 171 | 30 | 23 |
| Giovanni Carrara | LAN | mr | 38 | 6.33 | 3 | 0 | 1 | 15 | 0 | 0 | 0 | 27.0 | 29 | 21 | 19 | 11 | 20 | 10 | 0 |
| Hector Carrasco | LAA | mr | 36 | 3.30 | 4 | 3 | 0 | 56 | 3 | 1 | 0 | 128.0 | 119 | 47 | 47 | 36 | 89 | 13 | 14 |
| Lance Carter | LAN | mr | 31 | 2.70 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 3.1 | 4 | 1 | 1 | 1 | 1 | 0 | 0 |
| Santiago Casilla | Oak | mr | 26 | 0.00 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 2 | 0 | 0 |
| Scott Cassidy | SD | mr | 30 | 6.18 | 5 | 3 | 1 | 40 | 0 | 0 | 0 | 43.2 | 54 | 31 | 30 | 11 | 65 | 12 | 3 |
| Fabio Castro* |   | mr | 21 | 2.98 | 4 | 1 | 0 | 29 | 0 | 0 | 0 | 51.1 | 30 | 17 | 17 | 20 | 30 | 2 | 4 |
| Gustavo Chacin* | Tor | sp | 25 | 5.03 | 3 | 6 | 0 | 17 | 17 | 0 | 0 | 82.1 | 78 | 54 | 46 | 37 | 62 | 17 | 5 |
| Shawn Chacon |   | sp | 28 | 7.66 | 2 | 11 | 0 | 27 | 20 | 0 | 0 | 94.0 | 103 | 87 | 80 | 59 | 60 | 20 | 5 |
| Bruce Chen* | Bal | mr | 29 | 7.34 | 4 | 7 | 0 | 49 | 12 | 0 | 0 | 106.2 | 144 | 90 | 87 | 34 | 79 | 36 | 6 |
| Jason Childers | Tam | mr | 31 | 8.22 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 7.2 | 13 | 11 | 7 | 6 | 4 | 1 | 3 |
| Randy Choate* | Ari | mr | 30 | 6.04 | 0 | 0 | 0 | 21 | 0 | 0 | 0 | 22.1 | 33 | 16 | 15 | 3 | 11 | 1 | 5 |
| Vinnie Chulk |   | mr | 27 | 4.56 | 2 | 0 | 3 | 37 | 0 | 0 | 0 | 49.1 | 45 | 25 | 25 | 22 | 48 | 10 | 5 |
| Brandon Claussen* | Cin | sp | 27 | 7.05 | 1 | 7 | 0 | 14 | 14 | 0 | 0 | 60.0 | 85 | 50 | 47 | 42 | 54 | 12 | 4 |
| Roger Clemens | Hou | sp | 43 | 2.18 | 10 | 2 | 0 | 19 | 19 | 1 | 1 | 123.2 | 82 | 31 | 30 | 33 | 111 | 11 | 10 |
| Matt Clement | Bos | sp | 31 | 4.66 | 4 | 3 | 0 | 12 | 12 | 0 | 0 | 67.2 | 66 | 37 | 35 | 37 | 46 | 7 | 8 |
| Todd Coffey | Cin | mr | 25 | 3.94 | 6 | 3 | 4 | 88 | 0 | 0 | 0 | 102.2 | 115 | 51 | 45 | 31 | 67 | 13 | 18 |
| Bartolo Colon | LAA | sp | 33 | 4.17 | 3 | 1 | 0 | 10 | 10 | 0 | 0 | 58.1 | 65 | 29 | 27 | 8 | 40 | 11 | 3 |
| Roman Colon | Det | mr | 26 | 3.40 | 2 | 1 | 0 | 19 | 1 | 0 | 0 | 42.1 | 40 | 19 | 16 | 17 | 31 | 5 | 3 |
| Clay Condrey | Phi | mr | 30 | 5.10 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 30.0 | 39 | 18 | 17 | 10 | 14 | 4 | 8 |
| Jose Contreras | ChA | sp | 34 | 3.86 | 10 | 10 | 0 | 30 | 30 | 0 | 0 | 175.0 | 183 | 95 | 75 | 43 | 127 | 20 | 12 |
| Aaron Cook | Col | sp | 27 | 4.01 | 11 | 10 | 0 | 32 | 32 | 2 | 2 | 182.0 | 219 | 95 | 81 | 45 | 72 | 16 | 30 |
| Roy Corcoran | Was | mr | 26 | 4.50 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 6.0 | 9 | 3 | 3 | 1 | 1 | 1 | 0 |
| Tim Corcoran | Tam | sp | 28 | 4.34 | 4 | 5 | 0 | 24 | 16 | 0 | 0 | 91.1 | 91 | 46 | 44 | 52 | 52 | 8 | 10 |
| Chad Cordero | Was | cl | 24 | 3.79 | 3 | 6 | 31 | 78 | 0 | 0 | 0 | 92.2 | 81 | 39 | 39 | 25 | 83 | 16 | 0 |
| Francisco Cordero |   | cl | 31 | 3.46 | 5 | 3 | 8 | 80 | 0 | 0 | 0 | 93.2 | 78 | 37 | 36 | 33 | 113 | 11 | 2 |
| Bryan Corey |   | mr | 32 | 5.40 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 13.1 | 18 | 8 | 8 | 5 | 10 | 0 | 0 |
| Lance Cormier | Atl | mr | 25 | 7.41 | 2 | 1 | 1 | 32 | 9 | 0 | 0 | 71.2 | 91 | 62 | 59 | 39 | 36 | 8 | 12 |
| Rheal Cormier* |   | mr | 39 | 4.88 | 8 | 3 | 1 | 56 | 0 | 0 | 0 | 62.2 | 58 | 35 | 34 | 24 | 13 | 9 | 7 |
| Manuel Corpas | Col | mr | 23 | 5.81 | 1 | 1 | 1 | 18 | 0 | 0 | 0 | 26.1 | 40 | 18 | 17 | 5 | 24 | 1 | 2 |
| Kevin Correia | SF | mr | 25 | 3.40 | 3 | 3 | 2 | 57 | 0 | 0 | 0 | 92.2 | 80 | 37 | 35 | 38 | 79 | 7 | 2 |
| David Cortes | Col | mr | 32 | 2.62 | 4 | 1 | 0 | 31 | 0 | 0 | 0 | 44.2 | 58 | 17 | 13 | 8 | 26 | 3 | 5 |
| Neal Cotts* | ChA | mr | 26 | 3.83 | 7 | 3 | 1 | 68 | 0 | 0 | 0 | 87.0 | 71 | 42 | 37 | 47 | 63 | 14 | 8 |
| Jesse Crain | Min | mr | 24 | 2.47 | 4 | 2 | 5 | 53 | 0 | 0 | 0 | 69.1 | 52 | 20 | 19 | 18 | 52 | 4 | 4 |
| Francisco Cruceta | Sea | mr | 24 | 9.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 7 | 5 | 5 | 2 | 4 | 1 | 1 |
| Juan Cruz | Ari | mr | 27 | 3.09 | 8 | 5 | 0 | 35 | 15 | 0 | 0 | 116.1 | 92 | 46 | 40 | 54 | 102 | 6 | 13 |
| Casey Daigle | Ari | mr | 25 | 1.29 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 7.0 | 7 | 1 | 1 | 2 | 3 | 0 | 2 |
| Kyle Davies | Atl | sp | 22 | 7.89 | 3 | 4 | 0 | 14 | 14 | 0 | 0 | 51.1 | 67 | 50 | 45 | 34 | 39 | 9 | 7 |
| Doug Davis* | Mil | sp | 30 | 4.55 | 10 | 14 | 0 | 34 | 34 | 1 | 0 | 201.2 | 207 | 119 | 102 | 104 | 165 | 22 | 15 |
| Jason Davis | Cle | mr | 26 | 3.45 | 5 | 0 | 0 | 33 | 0 | 0 | 0 | 70.1 | 78 | 29 | 27 | 16 | 47 | 2 | 8 |
| Zach Day |   | sp | 28 | 4.95 | 1 | 4 | 0 | 8 | 8 | 0 | 0 | 40.0 | 55 | 24 | 22 | 8 | 15 | 3 | 4 |
| Jorge De La Rosa* |   | mr | 25 | 7.31 | 2 | 4 | 0 | 18 | 13 | 0 | 0 | 60.1 | 81 | 53 | 49 | 51 | 50 | 12 | 5 |
| Manny Delcarmen | Bos | mr | 24 | 5.37 | 3 | 1 | 1 | 31 | 0 | 0 | 0 | 52.0 | 60 | 32 | 31 | 17 | 40 | 4 | 5 |
| Chris Demaria | Mil | mr | 25 | 5.06 | 1 | 1 | 0 | 6 | 0 | 0 | 0 | 10.2 | 12 | 6 | 6 | 7 | 11 | 4 | 0 |
| Ryan Dempster | ChN | cl | 29 | 3.52 | 6 | 7 | 24 | 66 | 0 | 0 | 0 | 79.1 | 73 | 31 | 31 | 27 | 62 | 6 | 7 |
| Elmer Dessens |   | mr | 35 | 3.05 | 4 | 4 | 5 | 44 | 0 | 0 | 0 | 65.0 | 57 | 32 | 22 | 12 | 40 | 6 | 7 |
| Joey Devine | Atl | mr | 22 | 7.27 | 0 | 1 | 2 | 8 | 0 | 0 | 0 | 8.2 | 6 | 7 | 7 | 8 | 11 | 0 | 0 |
| R.A. Dickey | Tex | sp | 31 | 3.86 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 7.0 | 5 | 3 | 3 | 1 | 3 | 3 | 1 |
| Lenny DiNardo* | Bos | mr | 26 | 4.72 | 1 | 3 | 0 | 12 | 6 | 0 | 0 | 40.0 | 49 | 27 | 21 | 21 | 15 | 5 | 7 |
| Scott Dohmann |   | mr | 28 | 6.37 | 1 | 4 | 1 | 33 | 0 | 0 | 0 | 41.0 | 48 | 31 | 29 | 29 | 36 | 8 | 3 |
| Brendan Donnelly | LAA | mr | 34 | 2.53 | 6 | 6 | 4 | 56 | 0 | 0 | 0 | 74.2 | 46 | 24 | 21 | 30 | 55 | 8 | 7 |
| Octavio Dotel | NYA | mr | 32 | 27.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 2.2 | 9 | 8 | 8 | 4 | 1 | 1 | 0 |
| Scott Downs* | Tor | mr | 30 | 2.83 | 5 | 2 | 0 | 49 | 5 | 0 | 0 | 101.2 | 81 | 33 | 32 | 38 | 84 | 9 | 12 |
| Ryan Drese | Was | sp | 30 | 12.71 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 5.2 | 8 | 8 | 8 | 9 | 3 | 0 | 2 |
| Justin Duchscherer | Oak | mr | 28 | 1.78 | 3 | 2 | 2 | 45 | 0 | 0 | 0 | 60.2 | 47 | 13 | 12 | 14 | 61 | 3 | 3 |
| Brandon Duckworth | KC | sp | 30 | 6.35 | 2 | 3 | 1 | 9 | 8 | 0 | 0 | 39.2 | 55 | 32 | 28 | 12 | 21 | 5 | 4 |
| Zach Duke* | Pit | sp | 23 | 4.16 | 12 | 13 | 1 | 36 | 34 | 2 | 1 | 194.2 | 214 | 96 | 90 | 75 | 102 | 16 | 25 |
| Scott Dunn | Tam | mr | 28 | 5.06 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 10.2 | 16 | 7 | 6 | 3 | 2 | 0 | 0 |
| Chad Durbin | Det | mr | 28 | 1.23 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 7.1 | 6 | 1 | 1 | 2 | 4 | 0 | 1 |
| Adam Eaton | Tex | sp | 28 | 5.68 | 1 | 5 | 0 | 13 | 13 | 0 | 0 | 65.0 | 90 | 48 | 41 | 22 | 48 | 11 | 4 |
| Joey Eischen* | Was | mr | 36 | 3.50 | 0 | 3 | 0 | 15 | 0 | 0 | 0 | 18.0 | 17 | 8 | 7 | 18 | 18 | 0 | 4 |
| Scott Elarton | KC | sp | 30 | 5.01 | 7 | 6 | 0 | 20 | 20 | 0 | 0 | 102.1 | 107 | 67 | 57 | 46 | 51 | 18 | 8 |
| Alan Embree* | SD | mr | 36 | 4.59 | 6 | 2 | 0 | 71 | 0 | 0 | 0 | 64.2 | 62 | 33 | 33 | 23 | 75 | 4 | 11 |
| Scott Erickson | NYA | mr | 38 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Kelvim Escobar | LAA | sp | 30 | 3.30 | 14 | 6 | 0 | 30 | 30 | 2 | 1 | 188.0 | 183 | 82 | 69 | 47 | 138 | 14 | 18 |
| Shawn Estes* | SD | sp | 33 | 0.00 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 9.0 | 8 | 0 | 0 | 0 | 3 | 0 | 2 |
| Seth Etherton | KC | sp | 29 | 8.22 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 7.2 | 15 | 7 | 7 | 4 | 4 | 3 | 0 |
| Dana Eveland* | Mil | sp | 22 | 4.30 | 0 | 2 | 0 | 5 | 5 | 0 | 0 | 29.1 | 25 | 15 | 14 | 10 | 36 | 5 | 0 |
| Scott Eyre* | ChN | mr | 34 | 5.27 | 3 | 3 | 3 | 61 | 0 | 0 | 0 | 70.0 | 70 | 41 | 41 | 30 | 84 | 15 | 8 |
| Willie Eyre | Min | mr | 27 | 5.16 | 1 | 3 | 0 | 43 | 0 | 0 | 0 | 75.0 | 94 | 46 | 43 | 28 | 27 | 10 | 5 |
| Brian Falkenborg | StL | mr | 28 | 2.57 | 2 | 0 | 0 | 5 | 0 | 0 | 0 | 7.0 | 7 | 2 | 2 | 3 | 3 | 0 | 1 |
| Kyle Farnsworth | NYA | mr | 30 | 4.85 | 5 | 11 | 1 | 78 | 0 | 0 | 0 | 89.0 | 93 | 48 | 48 | 41 | 81 | 12 | 5 |
| Jeff Fassero* | SF | mr | 43 | 7.24 | 0 | 1 | 0 | 10 | 1 | 0 | 0 | 13.2 | 20 | 14 | 11 | 10 | 10 | 5 | 3 |
| Ryan Feierabend* | Sea | sp | 20 | 2.57 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 14.0 | 8 | 4 | 4 | 6 | 10 | 1 | 4 |
| Scott Feldman | Tex | mr | 23 | 4.47 | 3 | 4 | 2 | 43 | 0 | 0 | 0 | 54.1 | 63 | 30 | 27 | 14 | 36 | 6 | 4 |
| Pedro Feliciano* | NYN | mr | 29 | 4.85 | 7 | 7 | 3 | 76 | 0 | 0 | 0 | 72.1 | 78 | 44 | 39 | 37 | 55 | 7 | 6 |
| Nate Field | Col | mr | 30 | 4.50 | 0 | 0 | 2 | 7 | 0 | 0 | 0 | 6.0 | 7 | 4 | 3 | 3 | 7 | 1 | 0 |
| Randy Flores* | StL | mr | 30 | 4.59 | 7 | 5 | 3 | 77 | 0 | 0 | 0 | 66.2 | 61 | 34 | 34 | 29 | 62 | 11 | 7 |
| Ron Flores* | Oak | mr | 26 | 3.00 | 4 | 0 | 0 | 20 | 0 | 0 | 0 | 33.0 | 29 | 11 | 11 | 10 | 25 | 3 | 4 |
| Gavin Floyd | Phi | sp | 23 | 9.15 | 2 | 2 | 0 | 11 | 11 | 0 | 0 | 41.1 | 55 | 42 | 42 | 28 | 22 | 11 | 3 |
| Josh Fogg | Col | sp | 29 | 5.98 | 6 | 14 | 0 | 31 | 31 | 1 | 0 | 164.0 | 224 | 123 | 109 | 56 | 74 | 25 | 17 |
| Casey Fossum* | Tam | sp | 28 | 5.01 | 5 | 11 | 0 | 25 | 25 | 0 | 0 | 127.2 | 140 | 79 | 71 | 47 | 82 | 19 | 10 |
| Keith Foulke | Bos | mr | 33 | 4.02 | 3 | 3 | 1 | 47 | 0 | 0 | 0 | 62.2 | 60 | 29 | 28 | 8 | 44 | 13 | 3 |
| Jeff Francis* | Col | sp | 25 | 3.94 | 15 | 11 | 0 | 32 | 32 | 2 | 2 | 192.0 | 188 | 92 | 84 | 54 | 117 | 12 | 20 |
| Frank Francisco | Tex | mr | 26 | 13.50 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.0 | 9 | 6 | 6 | 1 | 3 | 2 | 0 |
| Ryan Franklin |   | mr | 33 | 4.80 | 7 | 5 | 2 | 71 | 0 | 0 | 0 | 84.1 | 96 | 52 | 45 | 21 | 47 | 10 | 8 |
| Wayne Franklin* | Atl | mr | 32 | 4.91 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 3.2 | 1 | 2 | 2 | 5 | 1 | 0 | 0 |
| Jason Frasor | Tor | mr | 28 | 4.76 | 0 | 2 | 3 | 52 | 0 | 0 | 0 | 68.0 | 67 | 37 | 36 | 28 | 73 | 16 | 3 |
| Emiliano Fruto | Sea | mr | 22 | 6.00 | 2 | 1 | 0 | 21 | 0 | 0 | 0 | 45.0 | 50 | 32 | 30 | 30 | 47 | 7 | 2 |
| Brian Fuentes* | Col | cl | 30 | 3.48 | 4 | 7 | 26 | 73 | 0 | 0 | 0 | 82.2 | 63 | 37 | 32 | 45 | 89 | 11 | 4 |
| Aaron Fultz* | Phi | mr | 32 | 4.86 | 2 | 2 | 0 | 55 | 1 | 0 | 0 | 70.1 | 95 | 40 | 38 | 34 | 60 | 7 | 7 |
| Kason Gabbard* | Bos | sp | 24 | 1.61 | 2 | 1 | 0 | 4 | 4 | 1 | 1 | 28.0 | 18 | 6 | 5 | 17 | 16 | 0 | 4 |
| Mike Gallo* | Hou | mr | 28 | 10.38 | 0 | 1 | 0 | 13 | 0 | 0 | 0 | 13.0 | 26 | 15 | 15 | 9 | 9 | 2 | 4 |
| Freddy Garcia | ChA | sp | 30 | 3.69 | 14 | 8 | 0 | 33 | 33 | 2 | 1 | 212.0 | 200 | 96 | 87 | 48 | 121 | 29 | 17 |
| Jose Garcia | Flo | mr | 21 | 0.00 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 6.0 | 4 | 0 | 0 | 2 | 1 | 0 | 0 |
| Jon Garland | ChA | sp | 26 | 5.26 | 10 | 13 | 0 | 32 | 32 | 4 | 2 | 174.2 | 221 | 108 | 102 | 37 | 92 | 24 | 24 |
| Matt Garza | Min | sp | 22 | 5.24 | 5 | 3 | 0 | 9 | 9 | 0 | 0 | 44.2 | 52 | 28 | 26 | 21 | 30 | 7 | 5 |
| Chad Gaudin | Oak | mr | 23 | 4.07 | 4 | 3 | 0 | 35 | 0 | 0 | 0 | 55.1 | 54 | 31 | 25 | 38 | 28 | 5 | 7 |
| Geoff Geary | Phi | mr | 29 | 2.15 | 5 | 2 | 0 | 62 | 0 | 0 | 0 | 92.0 | 98 | 24 | 22 | 29 | 65 | 4 | 14 |
| Franklyn German | Flo | mr | 26 | 1.27 | 1 | 1 | 1 | 18 | 0 | 0 | 0 | 21.1 | 17 | 5 | 3 | 10 | 12 | 1 | 0 |
| Justin Germano | Cin | sp | 23 | 5.40 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.0 | 2 | 3 | 3 | 0 | 4 | 2 | 1 |
| Tom Glavine* | NYN | sp | 40 | 5.13 | 9 | 11 | 0 | 32 | 32 | 0 | 0 | 166.2 | 199 | 100 | 95 | 52 | 112 | 14 | 16 |
| Jimmy Gobble* | KC | mr | 24 | 5.06 | 2 | 2 | 0 | 47 | 6 | 0 | 0 | 85.1 | 82 | 53 | 48 | 38 | 80 | 12 | 6 |
| Edgar Gonzalez | Ari | mr | 23 | 4.34 | 4 | 1 | 0 | 18 | 5 | 1 | 0 | 56.0 | 62 | 29 | 27 | 8 | 37 | 10 | 0 |
| Enrique Gonzalez | Ari | sp | 23 | 2.71 | 7 | 6 | 0 | 20 | 18 | 1 | 1 | 116.1 | 106 | 47 | 35 | 29 | 76 | 10 | 4 |
| Geremi Gonzalez |   | mr | 31 | 5.11 | 1 | 4 | 1 | 33 | 4 | 0 | 0 | 68.2 | 85 | 43 | 39 | 23 | 63 | 9 | 2 |
| Mike Gonzalez* | Pit | cl | 28 | 3.21 | 2 | 3 | 14 | 59 | 0 | 0 | 0 | 73.0 | 56 | 26 | 26 | 41 | 84 | 3 | 4 |
| Tom Gordon | Phi | cl | 38 | 5.35 | 4 | 6 | 22 | 62 | 0 | 0 | 0 | 69.0 | 70 | 45 | 41 | 30 | 75 | 18 | 7 |
| Tom Gorzelanny* | Pit | sp | 23 | 4.27 | 3 | 5 | 0 | 11 | 11 | 0 | 0 | 65.1 | 56 | 36 | 31 | 31 | 46 | 4 | 2 |
| Mike Gosling* | Cin | mr | 25 | 0.00 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| John Grabow* | Pit | mr | 27 | 4.71 | 0 | 1 | 2 | 58 | 0 | 0 | 0 | 80.1 | 74 | 45 | 42 | 31 | 80 | 11 | 8 |
| Danny Graves | Cle | mr | 32 | 2.35 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 7.2 | 9 | 2 | 2 | 3 | 0 | 1 | 2 |
| Sean Green | Sea | mr | 27 | 1.81 | 3 | 0 | 0 | 26 | 0 | 0 | 0 | 49.2 | 40 | 12 | 10 | 22 | 17 | 2 | 13 |
| Kevin Gregg | LAA | mr | 28 | 6.29 | 3 | 2 | 0 | 36 | 3 | 0 | 0 | 78.2 | 100 | 61 | 55 | 26 | 82 | 18 | 2 |
| Jason Grilli | Det | mr | 29 | 5.13 | 2 | 3 | 0 | 57 | 0 | 0 | 0 | 72.0 | 81 | 44 | 41 | 35 | 29 | 3 | 6 |
| Jason Grimsley | Ari | mr | 38 | 4.66 | 2 | 0 | 1 | 25 | 0 | 0 | 0 | 36.2 | 42 | 19 | 19 | 11 | 15 | 7 | 4 |
| Kevin Gryboski | Was | mr | 32 | 11.81 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 5.1 | 13 | 7 | 7 | 2 | 7 | 2 | 0 |
| Eddie Guardado* |   | cl | 35 | 5.77 | 1 | 3 | 2 | 41 | 0 | 0 | 0 | 34.1 | 39 | 23 | 22 | 18 | 41 | 8 | 3 |
| Matt Guerrier | Min | mr | 27 | 4.56 | 5 | 3 | 0 | 42 | 1 | 0 | 0 | 94.2 | 110 | 51 | 48 | 35 | 53 | 9 | 7 |
| Jeremy Guthrie | Cle | mr | 27 | 5.00 | 0 | 0 | 1 | 9 | 1 | 0 | 0 | 18.0 | 24 | 13 | 10 | 10 | 13 | 1 | 1 |
| Angel Guzman | ChN | sp | 24 | 8.45 | 1 | 8 | 0 | 16 | 10 | 0 | 0 | 43.2 | 62 | 49 | 41 | 26 | 45 | 12 | 0 |
| Charlie Haeger | ChA | mr | 22 | 7.15 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 11.1 | 17 | 10 | 9 | 11 | 10 | 0 | 0 |
| John Halama* | Bal | mr | 34 | 5.68 | 1 | 0 | 0 | 12 | 1 | 0 | 0 | 31.2 | 36 | 27 | 20 | 13 | 14 | 6 | 3 |
| Roy Halladay | Tor | sp | 29 | 2.94 | 19 | 8 | 0 | 33 | 32 | 5 | 2 | 223.1 | 201 | 80 | 73 | 50 | 128 | 25 | 17 |
| Brad Halsey* | Oak | mr | 25 | 3.68 | 3 | 4 | 2 | 35 | 7 | 0 | 0 | 88.0 | 86 | 45 | 36 | 38 | 53 | 6 | 10 |
| Cole Hamels* | Phi | sp | 22 | 3.50 | 10 | 6 | 0 | 23 | 23 | 1 | 0 | 136.1 | 113 | 57 | 53 | 56 | 155 | 16 | 8 |
| Jason Hammel | Tam | sp | 23 | 6.08 | 2 | 4 | 0 | 9 | 9 | 0 | 0 | 37.0 | 48 | 26 | 25 | 19 | 26 | 3 | 2 |
| Chris Hammond* | Cin | mr | 40 | 4.54 | 2 | 1 | 1 | 27 | 0 | 0 | 0 | 37.2 | 37 | 22 | 19 | 16 | 34 | 2 | 1 |
| Justin Hampson* | Col | mr | 26 | 4.05 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6.2 | 4 | 3 | 3 | 3 | 3 | 0 | 0 |
| Tim Hamulack* | LAN | mr | 29 | 5.75 | 1 | 0 | 1 | 34 | 0 | 0 | 0 | 40.2 | 47 | 28 | 26 | 20 | 42 | 7 | 6 |
| Josh Hancock | StL | mr | 28 | 3.74 | 1 | 0 | 2 | 54 | 0 | 0 | 0 | 84.1 | 81 | 39 | 35 | 28 | 55 | 9 | 12 |
| Devern Hansack | Bos | sp | 28 | 2.45 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 11.0 | 6 | 3 | 3 | 4 | 9 | 2 | 2 |
| Craig Hansen | Bos | mr | 22 | 5.87 | 1 | 0 | 2 | 14 | 0 | 0 | 0 | 23.0 | 25 | 15 | 15 | 9 | 16 | 5 | 1 |
| Aaron Harang | Cin | sp | 28 | 5.01 | 12 | 14 | 0 | 35 | 35 | 3 | 3 | 203.0 | 210 | 124 | 113 | 52 | 199 | 28 | 9 |
| Rich Harden | Oak | sp | 24 | 2.45 | 7 | 0 | 0 | 9 | 9 | 0 | 0 | 55.0 | 33 | 15 | 15 | 27 | 55 | 2 | 5 |
| Dan Haren | Oak | sp | 25 | 4.04 | 16 | 11 | 0 | 34 | 34 | 0 | 0 | 205.0 | 197 | 99 | 92 | 44 | 158 | 31 | 10 |
| Travis Harper | Tam | mr | 30 | 5.06 | 0 | 3 | 3 | 30 | 0 | 0 | 0 | 48.0 | 58 | 32 | 27 | 11 | 36 | 7 | 9 |
| Chad Harville | Tam | mr | 29 | 3.65 | 1 | 0 | 2 | 28 | 0 | 0 | 0 | 44.1 | 39 | 19 | 18 | 17 | 38 | 6 | 6 |
| LaTroy Hawkins | Bal | mr | 33 | 2.52 | 2 | 6 | 3 | 62 | 0 | 0 | 0 | 82.0 | 81 | 27 | 23 | 30 | 34 | 4 | 7 |
| Aaron Heilman | NYN | mr | 27 | 4.96 | 7 | 6 | 5 | 94 | 0 | 0 | 0 | 103.1 | 106 | 61 | 57 | 29 | 86 | 10 | 7 |
| Rick Helling | Mil | mr | 35 | 1.01 | 1 | 0 | 0 | 10 | 2 | 0 | 0 | 26.2 | 17 | 4 | 3 | 8 | 29 | 1 | 1 |
| Ben Hendrickson | Mil | sp | 25 | 8.10 | 0 | 3 | 0 | 3 | 3 | 0 | 0 | 10.0 | 10 | 14 | 9 | 13 | 6 | 0 | 0 |
| Mark Hendrickson* |   | sp | 32 | 3.69 | 14 | 4 | 0 | 25 | 25 | 2 | 0 | 158.2 | 144 | 68 | 65 | 65 | 82 | 12 | 14 |
| Sean Henn* | NYA | mr | 25 | 5.40 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.0 | 6 | 5 | 3 | 3 | 3 | 1 | 0 |
| Brad Hennessey | SF | mr | 26 | 5.30 | 4 | 3 | 2 | 36 | 12 | 0 | 0 | 107.0 | 112 | 64 | 63 | 42 | 47 | 17 | 8 |
| Clay Hensley | SD | sp | 26 | 4.38 | 8 | 9 | 0 | 36 | 29 | 0 | 0 | 164.1 | 168 | 90 | 80 | 81 | 105 | 13 | 18 |
| Matt Herges | Flo | mr | 36 | 4.57 | 1 | 2 | 1 | 48 | 0 | 0 | 0 | 69.0 | 96 | 40 | 35 | 19 | 41 | 5 | 12 |
| Dustin Hermanson | ChA | mr | 33 | 4.15 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 4.1 | 1 | 2 | 2 | 1 | 2 | 1 | 0 |
| Felix Hernandez | Sea | sp | 20 | 4.06 | 10 | 13 | 0 | 31 | 31 | 2 | 1 | 204.0 | 209 | 94 | 92 | 56 | 183 | 28 | 16 |
| Livan Hernandez |   | sp | 31 | 5.12 | 7 | 12 | 0 | 35 | 34 | 0 | 0 | 184.2 | 214 | 116 | 105 | 64 | 123 | 17 | 13 |
| Orlando Hernandez |   | sp | 36 | 4.42 | 12 | 7 | 0 | 30 | 29 | 1 | 0 | 173.0 | 150 | 101 | 85 | 68 | 172 | 23 | 4 |
| Roberto Hernandez |   | mr | 41 | 3.86 | 8 | 3 | 0 | 61 | 0 | 0 | 0 | 84.0 | 80 | 38 | 36 | 32 | 56 | 6 | 6 |
| Runelvys Hernandez | KC | sp | 28 | 6.77 | 5 | 11 | 0 | 21 | 21 | 0 | 0 | 103.2 | 138 | 85 | 78 | 50 | 41 | 22 | 11 |
| Rich Hill* | ChN | sp | 26 | 2.27 | 10 | 2 | 0 | 16 | 16 | 0 | 0 | 103.0 | 81 | 29 | 26 | 40 | 93 | 11 | 4 |
| Shawn Hill | Was | sp | 25 | 5.14 | 3 | 3 | 0 | 6 | 6 | 0 | 0 | 35.0 | 38 | 23 | 20 | 15 | 15 | 2 | 2 |
| Jason Hirsh | Hou | sp | 24 | 5.48 | 4 | 4 | 0 | 9 | 9 | 1 | 1 | 42.2 | 39 | 32 | 26 | 18 | 27 | 10 | 2 |
| James Hoey | Bal | mr | 23 | 4.80 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 15.0 | 17 | 10 | 8 | 11 | 8 | 2 | 1 |
| Trevor Hoffman | SD | cl | 38 | 2.72 | 1 | 4 | 40 | 74 | 0 | 0 | 0 | 86.0 | 72 | 26 | 26 | 17 | 69 | 11 | 6 |
| J.P. Howell* | Tam | sp | 23 | 5.45 | 1 | 4 | 0 | 8 | 8 | 0 | 0 | 39.2 | 47 | 29 | 24 | 16 | 32 | 5 | 9 |
| Bob Howry | ChN | mr | 32 | 2.88 | 10 | 3 | 1 | 88 | 0 | 0 | 0 | 109.1 | 104 | 40 | 35 | 23 | 94 | 9 | 6 |
| Jon Huber | Sea | mr | 24 | 3.68 | 3 | 0 | 0 | 14 | 0 | 0 | 0 | 22.0 | 20 | 11 | 9 | 9 | 7 | 3 | 2 |
| Luke Hudson | KC | sp | 29 | 5.43 | 1 | 11 | 0 | 32 | 15 | 0 | 0 | 107.2 | 143 | 79 | 65 | 39 | 65 | 8 | 16 |
| Tim Hudson | Atl | sp | 30 | 4.16 | 14 | 15 | 0 | 35 | 35 | 2 | 2 | 218.1 | 221 | 109 | 101 | 62 | 127 | 20 | 25 |
| Travis Hughes | Was | mr | 28 | 16.46 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 13.2 | 32 | 28 | 25 | 10 | 5 | 5 | 1 |
| Jason Isringhausen | StL | cl | 33 | 8.07 | 1 | 7 | 23 | 56 | 0 | 0 | 0 | 58.0 | 67 | 53 | 52 | 57 | 49 | 13 | 4 |
| Edwin Jackson | Tam | mr | 22 | 5.45 | 0 | 3 | 0 | 19 | 1 | 0 | 0 | 33.0 | 37 | 20 | 20 | 20 | 28 | 1 | 3 |
| Zach Jackson* | Mil | sp | 23 | 6.34 | 1 | 2 | 0 | 7 | 7 | 0 | 0 | 32.2 | 39 | 27 | 23 | 13 | 22 | 5 | 2 |
| Chuck James* | Atl | sp | 24 | 4.47 | 4 | 7 | 1 | 31 | 18 | 0 | 0 | 112.2 | 110 | 60 | 56 | 59 | 90 | 23 | 7 |
| Casey Janssen | Tor | sp | 24 | 5.27 | 5 | 7 | 0 | 17 | 17 | 2 | 0 | 99.0 | 117 | 63 | 58 | 25 | 37 | 27 | 10 |
| Kevin Jarvis |   | mr | 36 | 6.23 | 2 | 3 | 0 | 9 | 4 | 0 | 0 | 26.0 | 34 | 19 | 18 | 8 | 15 | 2 | 1 |
| Bobby Jenks | ChA | cl | 25 | 2.44 | 9 | 5 | 34 | 78 | 0 | 0 | 0 | 92.1 | 85 | 26 | 25 | 22 | 115 | 4 | 13 |
| Jason Jennings | Col | sp | 27 | 3.54 | 10 | 9 | 0 | 32 | 32 | 3 | 1 | 203.2 | 190 | 90 | 80 | 91 | 147 | 16 | 18 |
| Cesar Jimenez* | Sea | mr | 21 | 32.40 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1.2 | 5 | 6 | 6 | 1 | 0 | 3 | 0 |
| Ubaldo Jimenez | Col | sp | 22 | 7.50 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 6.0 | 8 | 5 | 5 | 2 | 6 | 0 | 0 |
| Jason Johnson |   | mr | 32 | 5.32 | 3 | 7 | 0 | 20 | 20 | 0 | 0 | 93.0 | 128 | 60 | 55 | 34 | 45 | 10 | 19 |
| Jim Johnson | Bal | sp | 23 | 33.75 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1.1 | 4 | 5 | 5 | 3 | 0 | 1 | 0 |
| Josh Johnson | Flo | sp | 22 | 4.10 | 9 | 7 | 0 | 29 | 24 | 0 | 0 | 140.1 | 150 | 70 | 64 | 55 | 144 | 17 | 8 |
| Randy Johnson* | NYA | sp | 42 | 3.21 | 19 | 4 | 0 | 34 | 33 | 1 | 1 | 202.0 | 180 | 80 | 72 | 65 | 175 | 21 | 10 |
| Tyler Johnson* | StL | mr | 25 | 7.18 | 4 | 5 | 5 | 49 | 0 | 0 | 0 | 36.1 | 41 | 30 | 29 | 24 | 42 | 5 | 2 |
| Greg Jones | LAA | mr | 29 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 2.0 | 6 | 3 | 0 | 1 | 0 | 0 | 0 |
| Todd Jones | Det | cl | 38 | 2.63 | 3 | 3 | 38 | 62 | 0 | 0 | 0 | 54.2 | 61 | 20 | 16 | 6 | 30 | 5 | 5 |
| Jorge Julio |   | cl | 27 | 4.10 | 2 | 6 | 18 | 53 | 0 | 0 | 0 | 59.1 | 51 | 27 | 27 | 36 | 73 | 7 | 2 |
| Steve Karsay | Oak | mr | 34 | 3.60 | 1 | 1 | 0 | 8 | 0 | 0 | 0 | 15.0 | 13 | 6 | 6 | 4 | 4 | 4 | 4 |
| Jeff Karstens | NYA | sp | 23 | 3.79 | 3 | 3 | 0 | 6 | 6 | 2 | 1 | 40.1 | 37 | 23 | 17 | 9 | 19 | 5 | 0 |
| Scott Kazmir* | Tam | sp | 22 | 4.51 | 5 | 10 | 0 | 24 | 24 | 0 | 0 | 135.2 | 120 | 76 | 68 | 66 | 181 | 12 | 4 |
| Randy Keisler* | Oak | mr | 30 | 6.35 | 2 | 0 | 0 | 9 | 0 | 0 | 0 | 11.1 | 18 | 9 | 8 | 8 | 5 | 4 | 2 |
| Joe Kennedy* | Oak | mr | 27 | 2.48 | 2 | 4 | 2 | 29 | 0 | 0 | 0 | 32.2 | 37 | 14 | 9 | 10 | 28 | 1 | 3 |
| Logan Kensing | Flo | mr | 23 | 7.34 | 1 | 3 | 2 | 41 | 0 | 0 | 0 | 41.2 | 47 | 37 | 34 | 18 | 53 | 14 | 2 |
| Bobby Keppel | KC | sp | 24 | 5.52 | 2 | 4 | 0 | 6 | 6 | 0 | 0 | 29.1 | 40 | 25 | 18 | 13 | 15 | 6 | 2 |
| Byung-Hyun Kim | Col | sp | 27 | 5.36 | 11 | 11 | 0 | 27 | 27 | 1 | 0 | 149.1 | 174 | 91 | 89 | 60 | 114 | 15 | 10 |
| Sun-Woo Kim |   | mr | 28 | 6.14 | 0 | 1 | 1 | 6 | 1 | 0 | 0 | 14.2 | 17 | 13 | 10 | 6 | 9 | 3 | 1 |
| Ray King* | Col | mr | 32 | 5.00 | 3 | 3 | 6 | 77 | 0 | 0 | 0 | 72.0 | 97 | 46 | 40 | 42 | 40 | 6 | 22 |
| Josh Kinney | StL | mr | 27 | 3.18 | 5 | 0 | 1 | 18 | 0 | 0 | 0 | 28.1 | 20 | 11 | 10 | 13 | 21 | 3 | 1 |
| Steve Kline* | SF | mr | 33 | 4.75 | 3 | 3 | 1 | 80 | 0 | 0 | 0 | 66.1 | 84 | 38 | 35 | 35 | 53 | 3 | 9 |
| Dan Kolb | Mil | mr | 31 | 4.41 | 9 | 10 | 1 | 89 | 0 | 0 | 0 | 96.0 | 112 | 51 | 47 | 42 | 54 | 9 | 12 |
| Shane Komine | Oak | sp | 25 | 8.00 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 9.0 | 9 | 8 | 8 | 5 | 2 | 4 | 1 |
| John Koronka* | Tex | sp | 25 | 4.76 | 7 | 8 | 0 | 23 | 23 | 0 | 0 | 111.2 | 145 | 65 | 59 | 32 | 65 | 15 | 6 |
| Hong-Chih Kuo* | LAN | mr | 24 | 2.71 | 2 | 2 | 0 | 29 | 5 | 0 | 0 | 69.2 | 59 | 25 | 21 | 22 | 86 | 4 | 4 |
| John Lackey | LAA | sp | 27 | 4.64 | 10 | 15 | 0 | 33 | 33 | 5 | 3 | 196.0 | 197 | 111 | 101 | 69 | 169 | 25 | 18 |
| Juan Lara* | Cle | mr | 25 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 2.1 | 0 | 1 | 0 | 2 | 3 | 0 | 0 |
| Brandon League | Tor | mr | 23 | 3.61 | 0 | 2 | 1 | 29 | 0 | 0 | 0 | 47.1 | 28 | 19 | 19 | 6 | 39 | 7 | 2 |
| Wilfredo Ledezma* | Det | mr | 25 | 4.85 | 2 | 4 | 0 | 27 | 7 | 0 | 0 | 59.1 | 73 | 35 | 32 | 15 | 35 | 9 | 1 |
| Cliff Lee* | Cle | sp | 27 | 4.99 | 9 | 10 | 0 | 33 | 33 | 1 | 1 | 176.2 | 215 | 105 | 98 | 55 | 113 | 21 | 11 |
| Justin Lehr | Mil | mr | 28 | 7.36 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 7.1 | 10 | 8 | 6 | 2 | 4 | 0 | 0 |
| Jon Lester* | Bos | sp | 22 | 4.44 | 5 | 4 | 0 | 15 | 15 | 0 | 0 | 77.0 | 84 | 43 | 38 | 36 | 65 | 5 | 9 |
| Colby Lewis | Det | mr | 26 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.0 | 1 | 0 | 0 | 1 | 0 | 0 | 2 |
| Brad Lidge | Hou | cl | 29 | 3.59 | 5 | 7 | 24 | 70 | 0 | 0 | 0 | 77.2 | 61 | 36 | 31 | 36 | 122 | 11 | 4 |
| Cory Lidle |   | sp | 34 | 5.07 | 9 | 9 | 0 | 30 | 30 | 0 | 0 | 161.2 | 172 | 101 | 91 | 63 | 109 | 28 | 24 |
| Jon Lieber | Phi | sp | 36 | 5.39 | 9 | 8 | 0 | 27 | 27 | 1 | 0 | 152.0 | 202 | 102 | 91 | 21 | 90 | 27 | 12 |
| Ted Lilly* | Tor | sp | 30 | 5.50 | 8 | 10 | 0 | 32 | 32 | 0 | 0 | 163.2 | 181 | 105 | 100 | 85 | 143 | 23 | 12 |
| Jose Lima | NYN | sp | 33 | 9.49 | 0 | 2 | 0 | 4 | 4 | 0 | 0 | 12.1 | 21 | 15 | 13 | 2 | 9 | 3 | 0 |
| Scott Linebrink | SD | mr | 29 | 4.26 | 7 | 9 | 0 | 82 | 0 | 0 | 0 | 88.2 | 106 | 43 | 42 | 24 | 68 | 11 | 2 |
| Francisco Liriano* | Min | sp | 22 | 2.61 | 11 | 6 | 0 | 33 | 16 | 3 | 2 | 141.1 | 85 | 46 | 41 | 47 | 174 | 9 | 15 |
| Wes Littleton | Tex | mr | 23 | 2.31 | 2 | 1 | 1 | 27 | 0 | 0 | 0 | 46.2 | 36 | 15 | 12 | 19 | 27 | 3 | 8 |
| Esteban Loaiza | Oak | sp | 34 | 3.83 | 11 | 6 | 0 | 26 | 26 | 3 | 1 | 167.0 | 158 | 75 | 71 | 48 | 96 | 15 | 13 |
| Kameron Loe | Tex | sp | 24 | 5.27 | 3 | 8 | 0 | 15 | 15 | 0 | 0 | 80.1 | 99 | 56 | 47 | 21 | 28 | 12 | 10 |
| Adam Loewen* | Bal | sp | 22 | 3.73 | 12 | 4 | 0 | 19 | 19 | 1 | 0 | 108.2 | 95 | 48 | 45 | 60 | 107 | 4 | 12 |
| Boone Logan* | ChA | mr | 21 | 3.18 | 0 | 1 | 0 | 12 | 0 | 0 | 0 | 22.2 | 18 | 9 | 8 | 8 | 23 | 0 | 2 |
| Kyle Lohse |   | sp | 27 | 4.54 | 8 | 9 | 0 | 31 | 19 | 0 | 0 | 123.0 | 152 | 66 | 62 | 37 | 100 | 14 | 14 |
| Braden Looper | StL | mr | 31 | 3.87 | 5 | 3 | 9 | 93 | 0 | 0 | 0 | 109.1 | 112 | 49 | 47 | 34 | 57 | 6 | 14 |
| Javier Lopez* | Bos | mr | 28 | 2.25 | 3 | 2 | 3 | 21 | 0 | 0 | 0 | 28.0 | 13 | 7 | 7 | 11 | 22 | 2 | 4 |
| Rodrigo Lopez | Bal | sp | 30 | 5.49 | 4 | 15 | 0 | 30 | 29 | 1 | 0 | 154.0 | 179 | 109 | 94 | 43 | 121 | 26 | 12 |
| Derek Lowe | LAN | sp | 33 | 4.19 | 12 | 15 | 0 | 34 | 34 | 2 | 1 | 206.0 | 219 | 111 | 96 | 60 | 127 | 18 | 21 |
| Mark Lowe | Sea | mr | 23 | 1.93 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 9.1 | 7 | 2 | 2 | 3 | 10 | 0 | 0 |
| Noah Lowry* | SF | sp | 25 | 4.59 | 7 | 10 | 0 | 27 | 27 | 1 | 1 | 147.0 | 159 | 82 | 75 | 50 | 93 | 21 | 13 |
| Ruddy Lugo | Tam | mr | 26 | 4.01 | 7 | 10 | 4 | 80 | 0 | 0 | 0 | 112.1 | 111 | 54 | 50 | 49 | 54 | 8 | 10 |
| Brandon Lyon | Ari | mr | 26 | 4.85 | 2 | 2 | 3 | 48 | 0 | 0 | 0 | 52.0 | 59 | 28 | 28 | 17 | 35 | 6 | 6 |
| Mike MacDougal |   | mr | 29 | 2.66 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 23.2 | 23 | 9 | 7 | 7 | 19 | 3 | 3 |
| Greg Maddux |   | sp | 40 | 3.83 | 7 | 15 | 0 | 34 | 34 | 1 | 1 | 202.0 | 228 | 95 | 86 | 39 | 130 | 21 | 26 |
| Ryan Madson | Phi | mr | 25 | 6.08 | 5 | 4 | 1 | 46 | 17 | 0 | 0 | 117.0 | 163 | 90 | 79 | 47 | 97 | 15 | 8 |
| Ron Mahay* | Tex | mr | 35 | 3.21 | 5 | 3 | 0 | 57 | 0 | 0 | 0 | 61.2 | 61 | 27 | 22 | 33 | 60 | 5 | 9 |
| Paul Maholm* | Pit | sp | 24 | 5.02 | 6 | 14 | 0 | 30 | 30 | 0 | 0 | 145.1 | 162 | 98 | 81 | 72 | 99 | 16 | 19 |
| John Maine | NYN | sp | 25 | 1.69 | 8 | 1 | 0 | 15 | 15 | 0 | 0 | 95.2 | 54 | 22 | 18 | 34 | 89 | 9 | 5 |
| Gary Majewski |   | mr | 26 | 4.28 | 6 | 2 | 3 | 56 | 0 | 0 | 0 | 69.1 | 74 | 38 | 33 | 29 | 43 | 5 | 7 |
| Julio Manon | Bal | mr | 32 | 9.30 | 2 | 0 | 0 | 22 | 0 | 0 | 0 | 30.0 | 42 | 33 | 31 | 18 | 21 | 9 | 0 |
| Shaun Marcum | Tor | sp | 24 | 5.56 | 5 | 6 | 0 | 15 | 14 | 0 | 0 | 69.2 | 78 | 53 | 43 | 35 | 47 | 18 | 5 |
| Carlos Marmol | ChN | sp | 23 | 4.95 | 5 | 9 | 0 | 22 | 13 | 0 | 0 | 76.1 | 60 | 48 | 42 | 59 | 59 | 10 | 3 |
| Mike Maroth* | Det | sp | 28 | 4.33 | 2 | 3 | 1 | 16 | 9 | 1 | 1 | 62.1 | 68 | 34 | 30 | 17 | 31 | 10 | 3 |
| Jason Marquis | StL | sp | 27 | 5.50 | 7 | 16 | 0 | 33 | 33 | 2 | 1 | 162.0 | 188 | 107 | 99 | 58 | 69 | 33 | 14 |
| Sean Marshall* | ChN | sp | 23 | 4.54 | 4 | 10 | 0 | 24 | 24 | 0 | 0 | 125.0 | 139 | 71 | 63 | 46 | 104 | 16 | 8 |
| Damaso Marte* | Pit | mr | 31 | 2.97 | 6 | 1 | 3 | 65 | 0 | 0 | 0 | 66.2 | 59 | 28 | 22 | 43 | 75 | 7 | 5 |
| Tom Martin* | Col | mr | 36 | 3.27 | 2 | 1 | 3 | 47 | 0 | 0 | 0 | 71.2 | 80 | 30 | 26 | 27 | 52 | 3 | 9 |
| Carlos Martinez | Flo | mr | 24 | 1.80 | 0 | 0 | 1 | 11 | 0 | 0 | 0 | 15.0 | 10 | 3 | 3 | 4 | 25 | 0 | 1 |
| Pedro Martinez | NYN | sp | 34 | 4.30 | 12 | 5 | 0 | 23 | 23 | 0 | 0 | 134.0 | 116 | 69 | 64 | 44 | 132 | 27 | 5 |
| Tom Mastny | Cle | cl | 25 | 9.49 | 3 | 8 | 10 | 24 | 0 | 0 | 0 | 24.2 | 43 | 29 | 26 | 9 | 20 | 2 | 1 |
| Juan Mateo | ChN | sp | 23 | 6.57 | 2 | 5 | 0 | 10 | 10 | 0 | 0 | 49.1 | 61 | 37 | 36 | 25 | 30 | 6 | 5 |
| Julio Mateo | Sea | mr | 28 | 4.76 | 3 | 2 | 1 | 38 | 0 | 0 | 0 | 45.1 | 56 | 26 | 24 | 18 | 30 | 6 | 4 |
| Scott Mathieson | Phi | sp | 22 | 11.71 | 1 | 5 | 0 | 9 | 8 | 0 | 0 | 27.2 | 49 | 38 | 36 | 8 | 24 | 9 | 1 |
| Joe Mays |   | sp | 30 | 7.82 | 1 | 3 | 0 | 10 | 10 | 0 | 0 | 35.2 | 55 | 35 | 31 | 21 | 13 | 7 | 7 |
| Macay McBride* | Atl | mr | 23 | 6.11 | 1 | 3 | 4 | 57 | 0 | 0 | 0 | 56.0 | 68 | 40 | 38 | 55 | 57 | 3 | 8 |
| Brandon McCarthy | ChA | mr | 22 | 3.91 | 2 | 4 | 2 | 55 | 2 | 0 | 0 | 112.2 | 111 | 56 | 49 | 44 | 91 | 17 | 8 |
| Seth McClung | Tam | mr | 25 | 7.48 | 5 | 9 | 5 | 32 | 15 | 1 | 1 | 80.2 | 98 | 67 | 67 | 58 | 45 | 11 | 6 |
| Dustin McGowan | Tor | mr | 24 | 4.62 | 1 | 3 | 0 | 7 | 3 | 0 | 0 | 25.1 | 27 | 14 | 13 | 13 | 23 | 1 | 2 |
| Marty McLeary | Pit | mr | 31 | 8.00 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 9.0 | 12 | 8 | 8 | 8 | 5 | 0 | 0 |
| Brian Meadows | Tam | mr | 30 | 5.12 | 6 | 6 | 4 | 65 | 0 | 0 | 0 | 114.1 | 154 | 72 | 65 | 21 | 54 | 22 | 13 |
| Gil Meche | Sea | sp | 27 | 4.78 | 9 | 12 | 0 | 32 | 32 | 0 | 0 | 175.0 | 176 | 100 | 93 | 77 | 135 | 27 | 15 |
| Brandon Medders | Ari | mr | 26 | 3.52 | 3 | 2 | 4 | 67 | 0 | 0 | 0 | 87.0 | 91 | 36 | 34 | 38 | 65 | 6 | 6 |
| Kent Mercker* | Cin | mr | 38 | 3.45 | 3 | 6 | 0 | 43 | 0 | 0 | 0 | 47.0 | 43 | 20 | 18 | 21 | 26 | 4 | 5 |
| Cla Meredith | SD | mr | 23 | 2.41 | 1 | 1 | 0 | 25 | 0 | 0 | 0 | 41.0 | 29 | 12 | 11 | 5 | 25 | 5 | 5 |
| Jose Mesa | Col | mr | 40 | 4.15 | 7 | 5 | 2 | 82 | 0 | 0 | 0 | 89.0 | 83 | 42 | 41 | 56 | 56 | 8 | 15 |
| Randy Messenger | Flo | mr | 24 | 6.23 | 3 | 2 | 1 | 28 | 0 | 0 | 0 | 39.0 | 45 | 29 | 27 | 12 | 25 | 11 | 4 |
| Dan Miceli | Tam | mr | 35 | 2.43 | 0 | 2 | 1 | 20 | 0 | 0 | 0 | 33.1 | 18 | 15 | 9 | 17 | 19 | 1 | 1 |
| Chris Michalak* | Cin | sp | 35 | 10.57 | 0 | 4 | 0 | 7 | 6 | 0 | 0 | 23.0 | 40 | 30 | 27 | 12 | 10 | 3 | 1 |
| Andrew Miller* | Det | mr | 21 | 4.15 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 4.1 | 4 | 4 | 2 | 11 | 1 | 0 | 0 |
| Matt Miller | Cle | mr | 34 | 13.50 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 4 | 4 | 4 | 2 | 4 | 2 | 0 |
| Trever Miller* | Hou | mr | 33 | 4.52 | 3 | 3 | 4 | 61 | 0 | 0 | 0 | 65.2 | 55 | 35 | 33 | 15 | 74 | 11 | 2 |
| Wade Miller | ChN | sp | 29 | 3.52 | 0 | 1 | 0 | 5 | 5 | 0 | 0 | 23.0 | 21 | 11 | 9 | 20 | 19 | 2 | 1 |
| Kevin Millwood | Tex | sp | 31 | 4.06 | 8 | 8 | 0 | 34 | 34 | 1 | 0 | 199.2 | 222 | 97 | 90 | 40 | 145 | 19 | 18 |
| Eric Milton* | Cin | sp | 30 | 3.64 | 9 | 8 | 0 | 26 | 26 | 0 | 0 | 153.1 | 171 | 78 | 62 | 42 | 96 | 18 | 3 |
| Zach Miner | Det | sp | 24 | 5.58 | 3 | 8 | 0 | 24 | 16 | 0 | 0 | 90.1 | 109 | 60 | 56 | 26 | 47 | 13 | 12 |
| Sergio Mitre | Flo | sp | 25 | 4.33 | 4 | 3 | 0 | 14 | 7 | 0 | 0 | 52.0 | 50 | 27 | 25 | 24 | 40 | 9 | 7 |
| Brian Moehler | Flo | sp | 34 | 6.37 | 5 | 8 | 0 | 29 | 21 | 0 | 0 | 118.2 | 153 | 86 | 84 | 38 | 67 | 19 | 12 |
| Agustin Montero | ChA | mr | 28 | 3.43 | 2 | 1 | 0 | 9 | 0 | 0 | 0 | 21.0 | 14 | 8 | 8 | 1 | 7 | 5 | 3 |
| Juan Morillo | Col | sp | 22 | 6.35 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.2 | 9 | 4 | 4 | 4 | 3 | 1 | 0 |
| Matt Morris | SF | sp | 31 | 4.34 | 15 | 12 | 0 | 34 | 33 | 1 | 1 | 186.2 | 189 | 102 | 90 | 44 | 109 | 23 | 9 |
| Dustin Moseley | LAA | sp | 24 | 7.36 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 7.1 | 12 | 9 | 6 | 1 | 4 | 1 | 1 |
| Guillermo Mota |   | mr | 32 | 2.90 | 7 | 1 | 1 | 63 | 0 | 0 | 0 | 83.2 | 73 | 28 | 27 | 22 | 81 | 8 | 4 |
| Jamie Moyer* |   | sp | 43 | 5.09 | 13 | 12 | 0 | 33 | 33 | 2 | 0 | 194.2 | 217 | 119 | 110 | 64 | 91 | 38 | 16 |
| Peter Moylan | Atl | mr | 27 | 4.62 | 2 | 1 | 0 | 15 | 0 | 0 | 0 | 25.1 | 29 | 13 | 13 | 3 | 31 | 3 | 0 |
| Edward Mujica | Cle | mr | 22 | 3.38 | 1 | 0 | 0 | 8 | 0 | 0 | 0 | 18.2 | 24 | 7 | 7 | 0 | 14 | 1 | 3 |
| Mark Mulder* | StL | sp | 28 | 7.83 | 2 | 6 | 0 | 17 | 17 | 0 | 0 | 77.0 | 109 | 71 | 67 | 37 | 37 | 23 | 8 |
| Terry Mulholland* | Ari | mr | 43 | 16.20 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.2 | 5 | 3 | 3 | 0 | 2 | 1 | 0 |
| Scott Munter | SF | mr | 26 | 9.74 | 0 | 2 | 0 | 18 | 0 | 0 | 0 | 20.1 | 31 | 22 | 22 | 14 | 11 | 2 | 3 |
| Mike Mussina | NYA | sp | 37 | 3.24 | 22 | 2 | 0 | 32 | 32 | 1 | 1 | 211.1 | 198 | 82 | 76 | 49 | 204 | 18 | 21 |
| Brett Myers | Phi | sp | 25 | 3.93 | 12 | 11 | 0 | 31 | 31 | 5 | 3 | 194.2 | 176 | 94 | 85 | 62 | 186 | 31 | 24 |
| Mike Myers* | NYA | mr | 37 | 2.70 | 4 | 1 | 3 | 60 | 0 | 0 | 0 | 56.2 | 58 | 19 | 17 | 20 | 35 | 5 | 7 |
| Chris Narveson* | StL | mr | 24 | 9.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 4.0 | 4 | 4 | 4 | 5 | 8 | 0 | 0 |
| Joe Nathan | Min | cl | 31 | 2.15 | 2 | 4 | 35 | 61 | 0 | 0 | 0 | 83.2 | 56 | 21 | 20 | 11 | 138 | 10 | 2 |
| Jeff Nelson | ChA | mr | 39 | 5.79 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 4.2 | 6 | 3 | 3 | 2 | 5 | 0 | 0 |
| Joe Nelson | KC | mr | 31 | 3.82 | 2 | 2 | 13 | 37 | 0 | 0 | 0 | 35.1 | 36 | 15 | 15 | 20 | 39 | 5 | 1 |
| Pat Neshek | Min | mr | 25 | 2.49 | 1 | 1 | 1 | 15 | 0 | 0 | 0 | 25.1 | 20 | 12 | 7 | 6 | 33 | 6 | 1 |
| Fernando Nieve | Hou | mr | 23 | 3.20 | 4 | 2 | 0 | 24 | 11 | 0 | 0 | 90.0 | 64 | 34 | 32 | 30 | 64 | 14 | 9 |
| Dustin Nippert | Ari | sp | 25 | 21.21 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 4.2 | 11 | 11 | 11 | 3 | 4 | 5 | 1 |
| Ricky Nolasco | Flo | sp | 23 | 4.81 | 4 | 11 | 0 | 25 | 22 | 0 | 0 | 136.2 | 157 | 82 | 73 | 44 | 87 | 16 | 12 |
| Roberto Novoa | ChN | mr | 26 | 4.37 | 1 | 3 | 0 | 57 | 0 | 0 | 0 | 80.1 | 87 | 44 | 39 | 34 | 59 | 12 | 3 |
| Leo Nunez | KC | mr | 22 | 3.06 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 17.2 | 20 | 6 | 6 | 7 | 15 | 2 | 5 |
| Mike O'Connor* | Was | sp | 25 | 4.31 | 6 | 8 | 0 | 20 | 20 | 0 | 0 | 110.2 | 101 | 56 | 53 | 53 | 61 | 14 | 6 |
| Eric O'Flaherty* | Sea | mr | 21 | 11.12 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 11.1 | 25 | 16 | 14 | 7 | 5 | 3 | 0 |
| Ryan O'Malley* | ChN | sp | 26 | 3.65 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 12.1 | 6 | 6 | 5 | 13 | 7 | 2 | 0 |
| Tomo Ohka | Mil | sp | 30 | 3.49 | 8 | 4 | 0 | 18 | 18 | 0 | 0 | 111.0 | 101 | 54 | 43 | 49 | 54 | 10 | 7 |
| Will Ohman* | ChN | mr | 28 | 4.66 | 6 | 2 | 3 | 78 | 0 | 0 | 0 | 85.0 | 68 | 48 | 44 | 58 | 79 | 12 | 6 |
| Darren Oliver* | NYN | mr | 35 | 3.17 | 5 | 2 | 5 | 55 | 0 | 0 | 0 | 99.1 | 74 | 43 | 35 | 28 | 75 | 15 | 9 |
| Scott Olsen* | Flo | sp | 22 | 4.26 | 13 | 12 | 0 | 31 | 31 | 0 | 0 | 183.2 | 180 | 95 | 87 | 68 | 159 | 29 | 19 |
| Ramon Ortiz | Was | sp | 33 | 6.35 | 8 | 15 | 0 | 34 | 33 | 1 | 0 | 181.1 | 225 | 136 | 128 | 62 | 106 | 27 | 12 |
| Russ Ortiz |   | sp | 32 | 11.10 | 5 | 11 | 0 | 40 | 11 | 0 | 0 | 71.1 | 109 | 93 | 88 | 43 | 58 | 33 | 8 |
| Chad Orvella | Tam | mr | 25 | 8.58 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 28.1 | 38 | 34 | 27 | 21 | 21 | 5 | 2 |
| Franquelis Osoria | LAN | mr | 24 | 8.10 | 0 | 1 | 0 | 15 | 0 | 0 | 0 | 20.0 | 32 | 20 | 18 | 15 | 11 | 5 | 6 |
| Roy Oswalt | Hou | sp | 28 | 4.17 | 11 | 10 | 0 | 32 | 32 | 1 | 0 | 198.2 | 202 | 98 | 92 | 48 | 134 | 13 | 29 |
| Akinori Otsuka | Tex | cl | 34 | 2.19 | 7 | 6 | 35 | 68 | 0 | 0 | 0 | 90.1 | 86 | 23 | 22 | 17 | 82 | 6 | 12 |
| Vicente Padilla | Tex | sp | 28 | 4.89 | 11 | 12 | 0 | 33 | 33 | 1 | 0 | 195.0 | 213 | 115 | 106 | 69 | 136 | 23 | 19 |
| Jonathan Papelbon | Bos | cl | 25 | 2.87 | 3 | 4 | 23 | 63 | 0 | 0 | 0 | 78.1 | 57 | 26 | 25 | 15 | 86 | 7 | 3 |
| Chan Ho Park | SD | sp | 33 | 6.71 | 3 | 12 | 0 | 21 | 21 | 2 | 0 | 104.2 | 142 | 88 | 78 | 31 | 73 | 15 | 7 |
| Chad Paronto | Atl | mr | 30 | 4.06 | 4 | 3 | 2 | 52 | 0 | 0 | 0 | 57.2 | 65 | 33 | 26 | 22 | 47 | 7 | 4 |
| John Patterson | Was | sp | 28 | 3.11 | 4 | 2 | 0 | 8 | 8 | 0 | 0 | 46.1 | 39 | 20 | 16 | 16 | 54 | 5 | 1 |
| David Pauley | Bos | sp | 23 | 7.07 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 14.0 | 23 | 11 | 11 | 4 | 6 | 1 | 5 |
| Jake Peavy | SD | sp | 25 | 3.59 | 13 | 6 | 0 | 32 | 32 | 5 | 1 | 208.0 | 191 | 91 | 83 | 66 | 215 | 21 | 13 |
| Mike Pelfrey | NYN | sp | 22 | 6.00 | 0 | 2 | 0 | 4 | 4 | 0 | 0 | 15.0 | 26 | 11 | 10 | 11 | 15 | 2 | 4 |
| Tony Pena | Ari | mr | 24 | 6.28 | 2 | 1 | 0 | 19 | 0 | 0 | 0 | 28.2 | 35 | 22 | 20 | 13 | 19 | 7 | 3 |
| Hayden Penn | Bal | sp | 21 | 18.64 | 0 | 5 | 0 | 6 | 6 | 0 | 0 | 14.0 | 35 | 31 | 29 | 10 | 4 | 8 | 1 |
| Brad Penny | LAN | sp | 28 | 4.48 | 11 | 13 | 0 | 33 | 33 | 1 | 0 | 183.0 | 205 | 97 | 91 | 43 | 143 | 18 | 18 |
| Joel Peralta | KC | mr | 30 | 3.50 | 5 | 3 | 8 | 56 | 0 | 0 | 0 | 69.1 | 67 | 34 | 27 | 21 | 62 | 6 | 4 |
| Beltran Perez | Was | mr | 24 | 5.79 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 14.0 | 13 | 10 | 9 | 9 | 8 | 5 | 1 |
| Juan Perez* | Pit | mr | 27 | 18.41 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 7.1 | 15 | 15 | 15 | 7 | 4 | 1 | 1 |
| Odalis Perez* |   | mr | 29 | 5.99 | 3 | 8 | 0 | 30 | 20 | 1 | 0 | 106.2 | 141 | 80 | 71 | 32 | 59 | 17 | 4 |
| Oliver Perez* |   | sp | 24 | 5.94 | 2 | 6 | 0 | 22 | 22 | 0 | 0 | 94.0 | 101 | 63 | 62 | 78 | 97 | 7 | 7 |
| Rafael Perez* | Cle | mr | 24 | 2.08 | 0 | 1 | 1 | 26 | 0 | 0 | 0 | 21.2 | 23 | 8 | 5 | 11 | 25 | 2 | 0 |
| Yusmeiro Petit | Flo | mr | 21 | 7.78 | 1 | 0 | 0 | 19 | 1 | 0 | 0 | 39.1 | 69 | 36 | 34 | 5 | 34 | 11 | 3 |
| Andy Pettitte* | Hou | sp | 34 | 5.28 | 8 | 15 | 0 | 35 | 35 | 0 | 0 | 187.2 | 216 | 111 | 110 | 76 | 167 | 35 | 29 |
| Joel Pineiro | Sea | sp | 27 | 5.47 | 4 | 10 | 0 | 35 | 25 | 0 | 0 | 144.2 | 180 | 91 | 88 | 47 | 81 | 27 | 17 |
| Renyel Pinto* | Flo | mr | 23 | 6.26 | 2 | 3 | 0 | 29 | 0 | 0 | 0 | 27.1 | 29 | 20 | 19 | 29 | 41 | 2 | 5 |
| Cliff Politte | ChA | mr | 32 | 7.85 | 0 | 3 | 1 | 13 | 0 | 0 | 0 | 18.1 | 27 | 16 | 16 | 5 | 10 | 6 | 1 |
| Sidney Ponson |   | sp | 29 | 5.99 | 4 | 3 | 0 | 16 | 16 | 0 | 0 | 79.2 | 100 | 61 | 53 | 29 | 54 | 7 | 13 |
| Mark Prior | ChN | sp | 25 | 5.29 | 0 | 6 | 0 | 9 | 9 | 0 | 0 | 47.2 | 41 | 29 | 28 | 21 | 40 | 12 | 2 |
| Scott Proctor | NYA | mr | 29 | 3.08 | 8 | 1 | 2 | 70 | 0 | 0 | 0 | 99.1 | 92 | 35 | 34 | 21 | 91 | 9 | 6 |
| J.J. Putz | Sea | cl | 29 | 0.86 | 6 | 4 | 36 | 63 | 0 | 0 | 0 | 83.1 | 56 | 11 | 8 | 13 | 97 | 2 | 10 |
| Chad Qualls | Hou | mr | 27 | 2.96 | 2 | 3 | 3 | 86 | 0 | 0 | 0 | 100.1 | 90 | 33 | 33 | 26 | 72 | 11 | 23 |
| Brad Radke | Min | sp | 33 | 5.56 | 8 | 8 | 0 | 28 | 28 | 1 | 0 | 153.2 | 215 | 101 | 95 | 31 | 87 | 27 | 17 |
| Elizardo Ramirez | Cin | sp | 23 | 5.93 | 3 | 6 | 0 | 19 | 19 | 0 | 0 | 85.0 | 117 | 63 | 56 | 29 | 53 | 13 | 8 |
| Horacio Ramirez* | Atl | sp | 26 | 4.48 | 3 | 3 | 0 | 14 | 14 | 0 | 0 | 78.1 | 94 | 41 | 39 | 26 | 41 | 5 | 9 |
| Ramon Ramirez | Col | mr | 24 | 4.48 | 2 | 1 | 1 | 49 | 0 | 0 | 0 | 72.1 | 71 | 41 | 36 | 34 | 70 | 6 | 4 |
| Darrell Rasner | NYA | sp | 25 | 6.46 | 2 | 1 | 0 | 3 | 3 | 0 | 0 | 15.1 | 15 | 11 | 11 | 5 | 5 | 3 | 0 |
| Jon Rauch | Was | mr | 27 | 4.33 | 8 | 6 | 2 | 79 | 0 | 0 | 0 | 95.2 | 92 | 51 | 46 | 54 | 91 | 15 | 4 |
| Chris Ray | Bal | cl | 24 | 4.45 | 6 | 7 | 26 | 69 | 0 | 0 | 0 | 85.0 | 67 | 45 | 42 | 42 | 68 | 17 | 6 |
| Ken Ray | Atl | mr | 31 | 4.29 | 4 | 4 | 6 | 73 | 0 | 0 | 0 | 79.2 | 66 | 41 | 38 | 48 | 75 | 10 | 3 |
| Britt Reames | Pit | mr | 32 | 8.68 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 9.1 | 16 | 11 | 9 | 7 | 6 | 3 | 2 |
| Mark Redman* | KC | sp | 32 | 5.33 | 3 | 12 | 0 | 29 | 29 | 1 | 0 | 155.1 | 176 | 99 | 92 | 63 | 62 | 17 | 18 |
| Chris Reitsma | Atl | cl | 28 | 8.77 | 0 | 5 | 5 | 41 | 0 | 0 | 0 | 39.0 | 63 | 43 | 38 | 6 | 17 | 13 | 1 |
| Mike Remlinger* | Atl | mr | 40 | 5.40 | 2 | 3 | 2 | 25 | 0 | 0 | 0 | 23.1 | 23 | 16 | 14 | 13 | 19 | 0 | 4 |
| Chris Resop | Flo | mr | 23 | 4.99 | 2 | 3 | 0 | 28 | 0 | 0 | 0 | 30.2 | 34 | 20 | 17 | 14 | 18 | 1 | 4 |
| Anthony Reyes | StL | sp | 24 | 4.48 | 5 | 4 | 0 | 17 | 17 | 0 | 0 | 96.1 | 77 | 50 | 48 | 33 | 83 | 18 | 5 |
| Dennys Reyes* | Min | mr | 29 | 1.74 | 4 | 2 | 0 | 54 | 0 | 0 | 0 | 51.2 | 46 | 14 | 10 | 14 | 47 | 2 | 6 |
| John Rheinecker* | Tex | sp | 27 | 4.40 | 5 | 4 | 0 | 15 | 13 | 0 | 0 | 73.2 | 94 | 41 | 36 | 24 | 25 | 8 | 7 |
| Arthur Rhodes* | Phi | mr | 36 | 5.13 | 7 | 6 | 1 | 67 | 0 | 0 | 0 | 72.0 | 96 | 43 | 41 | 27 | 79 | 5 | 3 |
| Juan Rincon | Min | mr | 27 | 1.59 | 8 | 4 | 4 | 79 | 0 | 0 | 0 | 96.0 | 81 | 21 | 17 | 24 | 85 | 3 | 11 |
| Ricardo Rincon* | StL | mr | 36 | 5.79 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 4.2 | 5 | 3 | 3 | 4 | 3 | 1 | 1 |
| Royce Ring* | NYN | mr | 25 | 7.30 | 0 | 2 | 2 | 13 | 0 | 0 | 0 | 12.1 | 12 | 10 | 10 | 9 | 3 | 4 | 0 |
| David Riske |   | mr | 29 | 3.31 | 6 | 4 | 2 | 54 | 0 | 0 | 0 | 65.1 | 68 | 30 | 24 | 27 | 45 | 4 | 7 |
| Mariano Rivera | NYA | cl | 36 | 1.86 | 7 | 2 | 28 | 68 | 0 | 0 | 0 | 82.1 | 62 | 17 | 17 | 11 | 68 | 5 | 13 |
| Saul Rivera | Was | mr | 28 | 3.80 | 2 | 3 | 1 | 51 | 0 | 0 | 0 | 71.0 | 71 | 39 | 30 | 39 | 48 | 3 | 4 |
| Sendy Rleal | Bal | mr | 26 | 6.75 | 2 | 1 | 1 | 34 | 0 | 0 | 0 | 46.2 | 49 | 36 | 35 | 30 | 31 | 10 | 4 |
| Nate Robertson* | Det | sp | 28 | 4.60 | 12 | 9 | 0 | 32 | 32 | 1 | 0 | 203.1 | 214 | 110 | 104 | 57 | 113 | 29 | 33 |
| Fernando Rodney | Det | mr | 29 | 3.93 | 6 | 7 | 2 | 63 | 0 | 0 | 0 | 66.1 | 57 | 33 | 29 | 25 | 59 | 10 | 7 |
| Eddy Rodriguez | Bal | mr | 24 | 6.75 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 9.1 | 13 | 9 | 7 | 5 | 4 | 3 | 0 |
| Felix Rodriguez | Was | mr | 33 | 5.40 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 21.2 | 19 | 14 | 13 | 19 | 14 | 3 | 0 |
| Francisco Rodriguez | LAA | cl | 24 | 1.98 | 6 | 4 | 24 | 56 | 0 | 0 | 0 | 72.2 | 45 | 17 | 16 | 16 | 82 | 5 | 1 |
| Wandy Rodriguez* | Hou | sp | 27 | 6.79 | 7 | 9 | 0 | 25 | 24 | 0 | 0 | 104.2 | 126 | 82 | 79 | 68 | 80 | 21 | 13 |
| Brian Rogers | Pit | mr | 23 | 7.50 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 12.0 | 13 | 10 | 10 | 4 | 11 | 3 | 1 |
| Kenny Rogers* | Det | sp | 41 | 3.13 | 18 | 6 | 0 | 34 | 33 | 3 | 0 | 218.2 | 205 | 90 | 76 | 72 | 94 | 15 | 27 |
| Davis Romero* | Tor | mr | 23 | 5.40 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 15.0 | 24 | 9 | 9 | 11 | 10 | 2 | 4 |
| J.C. Romero* | LAA | mr | 30 | 4.03 | 5 | 5 | 2 | 43 | 0 | 0 | 0 | 44.2 | 58 | 26 | 20 | 23 | 29 | 2 | 2 |
| Francisco Rosario | Tor | mr | 25 | 8.23 | 0 | 0 | 0 | 13 | 1 | 0 | 0 | 27.1 | 37 | 25 | 25 | 20 | 27 | 9 | 2 |
| Josh Rupe | Tex | mr | 23 | 5.48 | 2 | 0 | 1 | 19 | 0 | 0 | 0 | 42.2 | 62 | 28 | 26 | 13 | 11 | 1 | 13 |
| Glendon Rusch* | ChN | mr | 31 | 7.28 | 1 | 5 | 4 | 27 | 9 | 0 | 0 | 55.2 | 64 | 47 | 45 | 31 | 57 | 19 | 7 |
| B.J. Ryan* | Tor | cl | 30 | 0.55 | 6 | 1 | 41 | 65 | 0 | 0 | 0 | 82.0 | 37 | 6 | 5 | 31 | 103 | 1 | 6 |
| Jae Kuk Ryu | ChN | mr | 23 | 9.90 | 0 | 0 | 0 | 6 | 1 | 0 | 0 | 10.0 | 20 | 12 | 11 | 2 | 11 | 8 | 0 |
| Kirk Saarloos | Oak | mr | 27 | 5.43 | 5 | 6 | 0 | 35 | 16 | 1 | 1 | 126.0 | 141 | 79 | 76 | 47 | 45 | 19 | 10 |
| C.C. Sabathia* | Cle | sp | 25 | 3.33 | 12 | 7 | 0 | 28 | 28 | 2 | 2 | 186.1 | 171 | 78 | 69 | 34 | 173 | 18 | 13 |
| Takashi Saito | LAN | cl | 36 | 1.80 | 5 | 3 | 26 | 64 | 0 | 0 | 0 | 85.0 | 49 | 17 | 17 | 33 | 116 | 4 | 9 |
| Juan Salas | Tam | mr | 27 | 7.27 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 8.2 | 14 | 8 | 7 | 6 | 4 | 1 | 0 |
| Chris Sampson | Hou | mr | 28 | 1.17 | 3 | 1 | 1 | 14 | 3 | 0 | 0 | 38.1 | 17 | 6 | 5 | 4 | 18 | 2 | 1 |
| Brian Sanches | Phi | mr | 27 | 4.74 | 0 | 1 | 5 | 17 | 0 | 0 | 0 | 24.2 | 26 | 14 | 13 | 10 | 23 | 3 | 2 |
| Anibal Sanchez | Flo | sp | 22 | 3.83 | 8 | 4 | 0 | 17 | 17 | 1 | 0 | 105.2 | 102 | 46 | 45 | 37 | 83 | 9 | 6 |
| Duaner Sanchez | NYN | mr | 26 | 2.01 | 5 | 0 | 2 | 36 | 0 | 0 | 0 | 62.2 | 43 | 15 | 14 | 22 | 54 | 2 | 10 |
| Jonathan Sanchez* | SF | mr | 23 | 3.58 | 2 | 2 | 0 | 13 | 4 | 0 | 0 | 37.2 | 27 | 15 | 15 | 17 | 40 | 4 | 2 |
| Ervin Santana | LAA | sp | 23 | 4.25 | 12 | 14 | 0 | 33 | 33 | 0 | 0 | 197.0 | 192 | 106 | 93 | 57 | 138 | 31 | 14 |
| Johan Santana* | Min | sp | 27 | 3.32 | 15 | 8 | 0 | 34 | 34 | 6 | 4 | 225.1 | 182 | 87 | 83 | 54 | 262 | 20 | 9 |
| Julio Santana | Phi | mr | 33 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Victor Santos | Pit | sp | 29 | 5.40 | 3 | 9 | 3 | 44 | 19 | 1 | 0 | 130.0 | 170 | 90 | 78 | 39 | 83 | 17 | 22 |
| Dennis Sarfate | Mil | mr | 25 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Scott Sauerbeck* |   | mr | 34 | 5.94 | 1 | 4 | 1 | 35 | 0 | 0 | 0 | 36.1 | 32 | 26 | 24 | 27 | 24 | 3 | 5 |
| Joe Saunders* | LAA | sp | 25 | 2.90 | 7 | 2 | 0 | 13 | 13 | 0 | 0 | 71.1 | 81 | 32 | 23 | 30 | 51 | 4 | 15 |
| Curt Schilling | Bos | sp | 39 | 4.80 | 10 | 9 | 0 | 31 | 31 | 1 | 1 | 180.0 | 215 | 109 | 96 | 22 | 164 | 31 | 13 |
| Jason Schmidt | SF | sp | 33 | 3.45 | 10 | 9 | 0 | 32 | 32 | 1 | 1 | 206.0 | 196 | 87 | 79 | 64 | 183 | 24 | 15 |
| Scott Schoeneweis* |   | mr | 32 | 5.53 | 5 | 6 | 3 | 48 | 0 | 0 | 0 | 55.1 | 62 | 38 | 34 | 21 | 30 | 8 | 8 |
| Chris Schroder | Was | mr | 27 | 5.33 | 0 | 0 | 0 | 18 | 0 | 0 | 0 | 25.1 | 21 | 17 | 15 | 10 | 34 | 9 | 0 |
| Rudy Seanez |   | mr | 37 | 5.30 | 2 | 4 | 1 | 37 | 0 | 0 | 0 | 52.2 | 65 | 33 | 31 | 26 | 43 | 4 | 2 |
| Bobby Seay* | Det | mr | 28 | 1.61 | 3 | 1 | 0 | 18 | 0 | 0 | 0 | 22.1 | 16 | 7 | 4 | 6 | 19 | 0 | 2 |
| Aaron Sele | LAN | sp | 36 | 4.89 | 5 | 5 | 2 | 29 | 15 | 0 | 0 | 108.2 | 125 | 61 | 59 | 34 | 51 | 11 | 4 |
| Jae Seo |   | sp | 29 | 6.94 | 3 | 16 | 0 | 30 | 26 | 0 | 0 | 128.1 | 172 | 104 | 99 | 48 | 77 | 30 | 8 |
| Brian Shackelford* | Cin | mr | 29 | 6.38 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 18.1 | 21 | 15 | 13 | 9 | 14 | 7 | 1 |
| Josh Sharpless | Pit | mr | 25 | 2.60 | 0 | 0 | 0 | 13 | 0 | 0 | 0 | 17.1 | 9 | 5 | 5 | 16 | 16 | 0 | 0 |
| Ben Sheets | Mil | sp | 27 | 4.24 | 2 | 8 | 0 | 17 | 17 | 0 | 0 | 110.1 | 109 | 57 | 52 | 20 | 122 | 17 | 4 |
| George Sherrill* | Sea | mr | 29 | 3.81 | 3 | 3 | 1 | 59 | 0 | 0 | 0 | 54.1 | 54 | 24 | 23 | 48 | 58 | 2 | 2 |
| James Shields | Tam | sp | 24 | 5.91 | 5 | 12 | 0 | 21 | 21 | 0 | 0 | 112.2 | 146 | 84 | 74 | 36 | 86 | 16 | 12 |
| Scot Shields | LAA | mr | 30 | 2.92 | 1 | 4 | 4 | 68 | 0 | 0 | 0 | 98.2 | 82 | 33 | 32 | 22 | 93 | 13 | 9 |
| Jason Shiell | Atl | sp | 29 | 9.72 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 8.1 | 12 | 9 | 9 | 5 | 9 | 4 | 0 |
| Brian Shouse* |   | mr | 37 | 4.08 | 4 | 4 | 0 | 59 | 0 | 0 | 0 | 53.0 | 55 | 27 | 24 | 21 | 28 | 8 | 8 |
| Brian Sikorski |   | mr | 31 | 5.32 | 2 | 1 | 1 | 11 | 0 | 0 | 0 | 22.0 | 17 | 13 | 13 | 3 | 25 | 7 | 0 |
| Carlos Silva | Min | sp | 27 | 6.61 | 7 | 15 | 0 | 37 | 31 | 0 | 0 | 158.0 | 234 | 125 | 116 | 29 | 59 | 38 | 18 |
| Andrew Sisco* | KC | mr | 23 | 5.64 | 4 | 6 | 2 | 56 | 0 | 0 | 0 | 60.2 | 78 | 38 | 38 | 35 | 50 | 5 | 3 |
| Doug Slaten* | Ari | mr | 26 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.1 | 3 | 0 | 0 | 0 | 2 | 0 | 0 |
| Brian Slocum | Cle | mr | 25 | 21.00 | 0 | 0 | 0 | 3 | 2 | 0 | 0 | 6.0 | 17 | 14 | 14 | 5 | 3 | 2 | 0 |
| Aaron Small | NYA | mr | 34 | 5.12 | 0 | 1 | 0 | 10 | 3 | 0 | 0 | 19.1 | 19 | 11 | 11 | 12 | 7 | 5 | 2 |
| Matt Smith* |   | mr | 27 | 1.60 | 1 | 1 | 2 | 20 | 0 | 0 | 0 | 33.2 | 20 | 7 | 6 | 14 | 41 | 2 | 3 |
| Mike Smith | Min | sp | 28 | 18.00 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 2.0 | 4 | 4 | 4 | 1 | 4 | 0 | 0 |
| Travis Smith | Atl | sp | 33 | 33.75 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1.1 | 4 | 5 | 5 | 4 | 0 | 0 | 0 |
| John Smoltz | Atl | sp | 39 | 3.46 | 12 | 8 | 0 | 35 | 35 | 1 | 0 | 221.0 | 211 | 90 | 85 | 64 | 218 | 24 | 15 |
| Ian Snell | Pit | sp | 24 | 5.82 | 6 | 18 | 0 | 32 | 32 | 1 | 1 | 164.0 | 196 | 109 | 106 | 55 | 157 | 26 | 8 |
| Kyle Snyder |   | sp | 28 | 6.65 | 3 | 3 | 0 | 17 | 11 | 0 | 0 | 66.1 | 101 | 52 | 49 | 17 | 51 | 14 | 6 |
| Alay Soler | NYN | sp | 26 | 5.62 | 1 | 2 | 0 | 8 | 8 | 0 | 0 | 41.2 | 41 | 30 | 26 | 23 | 18 | 6 | 0 |
| Rafael Soriano | Sea | mr | 26 | 3.03 | 9 | 4 | 1 | 62 | 0 | 0 | 0 | 74.1 | 45 | 26 | 25 | 24 | 74 | 3 | 1 |
| Jorge Sosa |   | mr | 29 | 4.41 | 5 | 6 | 0 | 44 | 13 | 1 | 0 | 126.2 | 131 | 67 | 62 | 35 | 69 | 21 | 8 |
| Jeremy Sowers* | Cle | sp | 23 | 1.88 | 12 | 1 | 0 | 14 | 14 | 2 | 2 | 100.2 | 80 | 23 | 21 | 23 | 44 | 5 | 8 |
| Justin Speier | Tor | mr | 32 | 3.07 | 7 | 2 | 1 | 67 | 0 | 0 | 0 | 88.0 | 67 | 35 | 30 | 20 | 91 | 11 | 2 |
| Russ Springer | Hou | mr | 37 | 3.28 | 6 | 4 | 0 | 52 | 0 | 0 | 0 | 82.1 | 63 | 33 | 30 | 29 | 62 | 14 | 5 |
| Chris Spurling |   | mr | 29 | 2.30 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 15.2 | 11 | 5 | 4 | 5 | 5 | 1 | 1 |
| Jason Standridge | Cin | mr | 27 | 7.61 | 0 | 0 | 0 | 23 | 0 | 0 | 0 | 23.2 | 31 | 21 | 20 | 25 | 22 | 3 | 3 |
| Mike Stanton* |   | cl | 39 | 4.19 | 2 | 5 | 16 | 75 | 0 | 0 | 0 | 88.0 | 89 | 43 | 41 | 29 | 60 | 4 | 5 |
| Tim Stauffer | SD | sp | 24 | 1.29 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 7.0 | 5 | 1 | 1 | 1 | 5 | 0 | 1 |
| Steve Stemle | KC | mr | 29 | 13.50 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 8.2 | 19 | 13 | 13 | 5 | 5 | 1 | 0 |
| Brian Stokes | Tam | sp | 26 | 8.40 | 0 | 2 | 0 | 4 | 4 | 0 | 0 | 15.0 | 22 | 15 | 14 | 10 | 12 | 3 | 1 |
| Huston Street | Oak | cl | 22 | 1.69 | 1 | 3 | 33 | 66 | 0 | 0 | 0 | 85.0 | 78 | 17 | 16 | 21 | 85 | 2 | 3 |
| Eric Stults* | LAN | mr | 26 | 3.00 | 1 | 0 | 0 | 2 | 2 | 1 | 0 | 15.0 | 13 | 5 | 5 | 3 | 5 | 2 | 1 |
| Tanyon Sturtze | NYA | mr | 35 | 4.50 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 8.0 | 11 | 5 | 4 | 5 | 2 | 1 | 0 |
| Jeff Suppan | StL | sp | 31 | 4.61 | 16 | 6 | 0 | 32 | 32 | 1 | 0 | 185.1 | 188 | 102 | 95 | 58 | 108 | 19 | 21 |
| Brian Sweeney | SD | mr | 32 | 4.37 | 5 | 2 | 2 | 36 | 0 | 0 | 0 | 57.2 | 58 | 29 | 28 | 30 | 20 | 4 | 4 |
| Jon Switzer* | Tam | mr | 26 | 3.92 | 2 | 3 | 2 | 34 | 0 | 0 | 0 | 39.0 | 43 | 21 | 17 | 24 | 21 | 2 | 4 |
| Brian Tallet* | Tor | mr | 28 | 3.10 | 7 | 0 | 0 | 29 | 1 | 0 | 0 | 49.1 | 38 | 17 | 17 | 22 | 37 | 2 | 3 |
| Taylor Tankersley* | Flo | mr | 23 | 3.74 | 1 | 3 | 2 | 54 | 0 | 0 | 0 | 55.1 | 49 | 23 | 23 | 36 | 75 | 3 | 7 |
| Jack Taschner* | SF | mr | 28 | 11.47 | 0 | 1 | 0 | 10 | 0 | 0 | 0 | 13.1 | 30 | 18 | 17 | 7 | 4 | 5 | 2 |
| Jordan Tata | Det | mr | 24 | 1.65 | 2 | 0 | 0 | 16 | 0 | 0 | 0 | 27.1 | 23 | 6 | 5 | 14 | 6 | 0 | 4 |
| Ty Taubenheim | Tor | sp | 23 | 9.58 | 3 | 3 | 0 | 9 | 7 | 0 | 0 | 31.0 | 43 | 37 | 33 | 19 | 19 | 6 | 1 |
| Julian Tavarez | Bos | mr | 33 | 4.05 | 9 | 6 | 0 | 59 | 6 | 0 | 0 | 124.1 | 123 | 57 | 56 | 55 | 71 | 12 | 23 |
| Robinson Tejeda | Tex | sp | 24 | 6.56 | 5 | 6 | 0 | 14 | 14 | 0 | 0 | 70.0 | 77 | 53 | 51 | 40 | 37 | 11 | 4 |
| Brad Thompson | StL | mr | 24 | 3.70 | 1 | 3 | 0 | 25 | 1 | 1 | 1 | 48.2 | 50 | 21 | 20 | 15 | 33 | 4 | 13 |
| Mike Thompson | SD | sp | 25 | 4.60 | 6 | 6 | 0 | 16 | 16 | 1 | 1 | 90.0 | 112 | 53 | 46 | 23 | 36 | 9 | 11 |
| John Thomson | Atl | sp | 32 | 5.89 | 5 | 8 | 0 | 16 | 15 | 0 | 0 | 88.2 | 106 | 64 | 58 | 27 | 47 | 21 | 3 |
| Matt Thornton* | ChA | mr | 29 | 3.58 | 3 | 3 | 4 | 54 | 0 | 0 | 0 | 65.1 | 62 | 27 | 26 | 23 | 52 | 9 | 4 |
| Mike Timlin | Bos | mr | 40 | 5.10 | 5 | 10 | 3 | 79 | 0 | 0 | 0 | 97.0 | 125 | 56 | 55 | 15 | 49 | 6 | 8 |
| Brett Tomko | LAN | mr | 33 | 4.07 | 10 | 4 | 0 | 36 | 15 | 1 | 1 | 126.0 | 135 | 61 | 57 | 27 | 103 | 21 | 8 |
| Salomon Torres | Pit | mr | 34 | 5.60 | 6 | 4 | 2 | 79 | 0 | 0 | 0 | 82.0 | 114 | 57 | 51 | 30 | 67 | 5 | 12 |
| Josh Towers | Tor | sp | 29 | 7.80 | 2 | 6 | 0 | 12 | 12 | 0 | 0 | 47.1 | 70 | 47 | 41 | 18 | 30 | 12 | 3 |
| Billy Traber* | Was | sp | 26 | 7.34 | 3 | 2 | 0 | 15 | 8 | 0 | 0 | 38.0 | 53 | 37 | 31 | 16 | 22 | 5 | 3 |
| Sean Tracey | ChA | mr | 25 | 5.79 | 1 | 1 | 0 | 7 | 0 | 0 | 0 | 9.1 | 7 | 6 | 6 | 8 | 5 | 0 | 2 |
| Steve Trachsel | NYN | sp | 35 | 6.60 | 8 | 12 | 0 | 30 | 30 | 0 | 0 | 139.0 | 168 | 112 | 102 | 64 | 64 | 17 | 13 |
| Derrick Turnbow | Mil | cl | 28 | 6.71 | 2 | 7 | 19 | 54 | 0 | 0 | 0 | 52.1 | 62 | 43 | 39 | 39 | 69 | 10 | 4 |
| Jose Valverde | Ari | cl | 26 | 4.67 | 1 | 3 | 11 | 31 | 0 | 0 | 0 | 34.2 | 38 | 19 | 18 | 20 | 46 | 7 | 0 |
| Jermaine Van Buren | Bos | mr | 25 | 7.98 | 0 | 1 | 2 | 10 | 0 | 0 | 0 | 14.2 | 19 | 15 | 13 | 18 | 12 | 0 | 1 |
| Claudio Vargas | Ari | sp | 28 | 5.61 | 6 | 15 | 0 | 30 | 30 | 0 | 0 | 160.1 | 183 | 107 | 100 | 52 | 99 | 28 | 6 |
| Jason Vargas* | Flo | mr | 23 | 6.39 | 2 | 2 | 1 | 14 | 5 | 0 | 0 | 38.0 | 47 | 29 | 27 | 19 | 34 | 8 | 1 |
| Javier Vazquez | ChA | sp | 29 | 3.46 | 17 | 7 | 0 | 32 | 32 | 3 | 0 | 215.2 | 208 | 89 | 83 | 57 | 171 | 18 | 25 |
| Mike Venafro* | Col | mr | 32 | 2.25 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 4.0 | 3 | 2 | 1 | 2 | 3 | 0 | 1 |
| Jose Veras | NYA | mr | 25 | 2.39 | 3 | 0 | 2 | 19 | 0 | 0 | 0 | 26.1 | 19 | 9 | 7 | 12 | 10 | 2 | 4 |
| Justin Verlander | Det | sp | 23 | 4.71 | 10 | 12 | 0 | 30 | 30 | 0 | 0 | 177.2 | 194 | 102 | 93 | 62 | 114 | 25 | 15 |
| Carlos Villanueva | Mil | sp | 22 | 5.21 | 1 | 1 | 0 | 6 | 6 | 0 | 0 | 38.0 | 37 | 24 | 22 | 7 | 30 | 10 | 2 |
| Oscar Villarreal | Atl | mr | 24 | 3.80 | 8 | 3 | 0 | 58 | 4 | 0 | 0 | 120.2 | 123 | 57 | 51 | 27 | 69 | 24 | 8 |
| Ron Villone* | NYA | mr | 36 | 3.69 | 2 | 1 | 1 | 46 | 0 | 0 | 0 | 78.0 | 61 | 33 | 32 | 42 | 80 | 9 | 0 |
| Luis Vizcaino | Ari | mr | 31 | 3.80 | 8 | 2 | 2 | 69 | 0 | 0 | 0 | 87.2 | 67 | 41 | 37 | 37 | 90 | 16 | 9 |
| Ryan Vogelsong | Pit | mr | 28 | 5.43 | 1 | 3 | 3 | 28 | 0 | 0 | 0 | 56.1 | 72 | 35 | 34 | 33 | 39 | 3 | 7 |
| Edinson Volquez | Tex | sp | 22 | 5.25 | 1 | 6 | 0 | 8 | 8 | 0 | 0 | 36.0 | 50 | 30 | 21 | 10 | 15 | 5 | 3 |
| Doug Waechter | Tam | sp | 25 | 3.59 | 3 | 5 | 0 | 10 | 10 | 0 | 0 | 57.2 | 71 | 29 | 23 | 15 | 23 | 2 | 7 |
| Billy Wagner* | NYN | cl | 34 | 2.93 | 5 | 3 | 28 | 77 | 0 | 0 | 0 | 89.0 | 82 | 32 | 29 | 30 | 131 | 8 | 7 |
| Ryan Wagner | Was | mr | 23 | 8.35 | 1 | 0 | 0 | 23 | 0 | 0 | 0 | 32.1 | 50 | 33 | 30 | 21 | 18 | 7 | 4 |
| Adam Wainwright | StL | mr | 24 | 3.05 | 9 | 3 | 0 | 54 | 0 | 0 | 0 | 85.2 | 75 | 31 | 29 | 33 | 78 | 5 | 7 |
| Tim Wakefield | Bos | sp | 39 | 5.51 | 5 | 11 | 0 | 24 | 23 | 0 | 0 | 125.2 | 133 | 81 | 77 | 56 | 82 | 15 | 9 |
| Jamie Walker* | Det | mr | 34 | 2.90 | 2 | 3 | 1 | 69 | 0 | 0 | 0 | 59.0 | 44 | 22 | 19 | 13 | 34 | 7 | 9 |
| Pete Walker | Tor | mr | 37 | 6.89 | 5 | 1 | 0 | 29 | 0 | 0 | 0 | 48.1 | 66 | 38 | 37 | 20 | 42 | 9 | 4 |
| Tyler Walker |   | mr | 30 | 1.99 | 1 | 2 | 9 | 25 | 0 | 0 | 0 | 31.2 | 21 | 10 | 7 | 10 | 29 | 1 | 4 |
| Les Walrond* | ChN | mr | 29 | 6.53 | 2 | 1 | 0 | 10 | 2 | 0 | 0 | 20.2 | 28 | 16 | 15 | 10 | 28 | 6 | 0 |
| Chien-Ming Wang | NYA | sp | 26 | 3.38 | 18 | 6 | 0 | 33 | 33 | 4 | 0 | 223.2 | 228 | 91 | 84 | 53 | 65 | 8 | 35 |
| John Wasdin | Tex | sp | 33 | 2.70 | 2 | 1 | 0 | 5 | 5 | 1 | 1 | 33.1 | 26 | 12 | 10 | 9 | 13 | 1 | 2 |
| Jarrod Washburn* | Sea | sp | 31 | 4.15 | 9 | 15 | 0 | 31 | 31 | 2 | 1 | 182.1 | 179 | 99 | 84 | 55 | 101 | 29 | 19 |
| David Weathers | Cin | mr | 36 | 2.84 | 2 | 3 | 27 | 73 | 0 | 0 | 0 | 79.1 | 65 | 32 | 25 | 22 | 48 | 13 | 7 |
| Jeff Weaver |   | sp | 29 | 5.93 | 6 | 12 | 0 | 31 | 31 | 2 | 0 | 159.1 | 195 | 114 | 105 | 48 | 103 | 32 | 10 |
| Jered Weaver | LAA | sp | 23 | 3.43 | 8 | 6 | 0 | 19 | 19 | 2 | 2 | 123.1 | 97 | 56 | 47 | 41 | 105 | 18 | 6 |
| Brandon Webb | Ari | sp | 27 | 4.15 | 14 | 13 | 0 | 33 | 33 | 5 | 0 | 229.2 | 226 | 120 | 106 | 48 | 157 | 14 | 22 |
| Todd Wellemeyer |   | mr | 27 | 3.33 | 4 | 2 | 1 | 52 | 0 | 0 | 0 | 102.2 | 84 | 45 | 38 | 74 | 60 | 8 | 20 |
| David Wells* |   | sp | 43 | 3.05 | 6 | 1 | 0 | 13 | 13 | 1 | 1 | 79.2 | 83 | 29 | 27 | 12 | 45 | 5 | 9 |
| Kip Wells |   | sp | 29 | 8.63 | 1 | 6 | 0 | 10 | 9 | 0 | 0 | 32.1 | 50 | 33 | 31 | 18 | 14 | 5 | 7 |
| Jake Westbrook | Cle | sp | 28 | 3.17 | 18 | 6 | 0 | 32 | 32 | 4 | 1 | 201.1 | 232 | 77 | 71 | 58 | 99 | 11 | 34 |
| Dan Wheeler | Hou | mr | 28 | 3.45 | 4 | 6 | 7 | 65 | 0 | 0 | 0 | 75.2 | 68 | 31 | 29 | 28 | 74 | 8 | 3 |
| Rick White |   | mr | 37 | 7.53 | 6 | 3 | 2 | 64 | 0 | 0 | 0 | 77.2 | 99 | 69 | 65 | 31 | 49 | 17 | 4 |
| Bob Wickman |   | cl | 37 | 2.98 | 8 | 9 | 30 | 60 | 0 | 0 | 0 | 66.1 | 74 | 30 | 22 | 19 | 58 | 3 | 7 |
| Dave Williams* |   | sp | 27 | 4.17 | 4 | 5 | 0 | 13 | 13 | 1 | 0 | 73.1 | 77 | 36 | 34 | 25 | 31 | 11 | 12 |
| Jerome Williams | ChN | mr | 24 | 4.82 | 1 | 1 | 0 | 3 | 2 | 0 | 0 | 9.1 | 17 | 6 | 5 | 8 | 4 | 0 | 1 |
| Todd Williams | Bal | mr | 35 | 5.72 | 3 | 6 | 6 | 74 | 0 | 0 | 0 | 83.1 | 121 | 61 | 53 | 23 | 32 | 14 | 14 |
| Woody Williams | SD | sp | 39 | 5.03 | 7 | 8 | 0 | 24 | 24 | 0 | 0 | 136.0 | 152 | 84 | 76 | 28 | 62 | 15 | 6 |
| Scott Williamson |   | mr | 30 | 5.75 | 1 | 1 | 1 | 44 | 0 | 0 | 0 | 51.2 | 58 | 35 | 33 | 35 | 54 | 5 | 8 |
| Dontrelle Willis* | Flo | sp | 24 | 4.03 | 16 | 11 | 0 | 34 | 34 | 1 | 0 | 218.2 | 223 | 107 | 98 | 91 | 163 | 25 | 29 |
| Brian Wilson | SF | mr | 24 | 5.86 | 3 | 7 | 3 | 43 | 0 | 0 | 0 | 43.0 | 53 | 30 | 28 | 26 | 34 | 5 | 2 |
| C.J. Wilson* | Tex | mr | 25 | 6.89 | 2 | 4 | 1 | 30 | 0 | 0 | 0 | 32.2 | 34 | 26 | 25 | 15 | 30 | 6 | 5 |
| Kris Wilson | NYA | mr | 29 | 27.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1.2 | 7 | 5 | 5 | 0 | 0 | 2 | 0 |
| Jason Windsor | Oak | sp | 23 | 12.38 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 8.0 | 17 | 12 | 11 | 8 | 4 | 1 | 2 |
| Joe Winkelsas | Mil | mr | 32 | 7.30 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 12.1 | 19 | 10 | 10 | 10 | 5 | 3 | 3 |
| Matt Wise | Mil | mr | 30 | 4.41 | 4 | 3 | 6 | 43 | 0 | 0 | 0 | 51.0 | 52 | 27 | 25 | 9 | 30 | 7 | 4 |
| Jay Witasick | Oak | mr | 33 | 12.18 | 0 | 0 | 0 | 11 | 0 | 0 | 0 | 17.0 | 29 | 23 | 23 | 23 | 18 | 5 | 1 |
| Randy Wolf* | Phi | sp | 29 | 7.93 | 2 | 2 | 0 | 12 | 12 | 0 | 0 | 42.0 | 57 | 39 | 37 | 26 | 32 | 7 | 3 |
| Kerry Wood | ChN | sp | 29 | 7.00 | 1 | 1 | 0 | 4 | 4 | 0 | 0 | 18.0 | 23 | 18 | 14 | 6 | 16 | 8 | 1 |
| Mike Wood | KC | mr | 26 | 6.00 | 5 | 3 | 0 | 35 | 7 | 0 | 0 | 90.0 | 124 | 71 | 60 | 26 | 40 | 14 | 10 |
| Jake Woods* | Sea | mr | 24 | 2.85 | 5 | 6 | 0 | 46 | 8 | 0 | 0 | 129.2 | 117 | 44 | 41 | 60 | 88 | 7 | 18 |
| Tim Worrell | SF | cl | 38 | 4.70 | 2 | 0 | 5 | 22 | 0 | 0 | 0 | 23.0 | 21 | 12 | 12 | 10 | 12 | 2 | 1 |
| Jamey Wright | SF | sp | 31 | 4.80 | 10 | 9 | 0 | 33 | 21 | 3 | 1 | 137.0 | 147 | 77 | 73 | 51 | 70 | 15 | 24 |
| Jaret Wright | NYA | sp | 30 | 4.00 | 11 | 4 | 1 | 28 | 27 | 1 | 1 | 139.2 | 160 | 64 | 62 | 64 | 76 | 12 | 16 |
| Michael Wuertz | ChN | mr | 27 | 1.96 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 23.0 | 12 | 6 | 5 | 6 | 27 | 2 | 0 |
| Esteban Yan |   | mr | 31 | 5.59 | 1 | 1 | 0 | 29 | 0 | 0 | 0 | 48.1 | 43 | 30 | 30 | 30 | 31 | 9 | 7 |
| Tyler Yates | Atl | mr | 28 | 3.54 | 3 | 1 | 4 | 36 | 0 | 0 | 0 | 48.1 | 41 | 24 | 19 | 29 | 62 | 7 | 4 |
| Shane Youman* | Pit | sp | 26 | 3.50 | 1 | 2 | 0 | 3 | 3 | 0 | 0 | 18.0 | 11 | 8 | 7 | 9 | 4 | 2 | 4 |
| Chris Young | SD | sp | 27 | 3.36 | 14 | 9 | 0 | 31 | 31 | 2 | 2 | 182.0 | 133 | 75 | 68 | 70 | 175 | 24 | 6 |
| Carlos Zambrano | ChN | sp | 25 | 4.27 | 11 | 10 | 0 | 33 | 33 | 1 | 1 | 212.2 | 163 | 111 | 101 | 106 | 220 | 27 | 13 |
| Victor Zambrano | NYN | sp | 30 | 3.47 | 3 | 2 | 0 | 5 | 5 | 0 | 0 | 23.1 | 20 | 12 | 9 | 19 | 20 | 1 | 1 |
| Barry Zito* | Oak | sp | 28 | 3.24 | 16 | 11 | 0 | 34 | 34 | 0 | 0 | 216.1 | 193 | 84 | 78 | 82 | 155 | 23 | 25 |
| Joel Zumaya | Det | mr | 21 | 4.38 | 6 | 5 | 3 | 70 | 0 | 0 | 0 | 72.0 | 70 | 38 | 35 | 25 | 85 | 11 | 3 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| David Aardsma | ChN | mr | 24 | 4 | 1 | 0 | 2 | 1 | 0 | 4 | 2 | 9.1 | 4.9 | 14.5 | 7.7 | 2.3 | 1.6 | 1.56 |
| Winston Abreu | Bal | mr | 29 | 1 | 0 | 0 | 3 | 1 | 1 | 0 | 2 | 13.2 | 6.3 | 21.3 | 4.6 | 2.3 | 0.7 | 2.17 |
| Jeremy Accardo |   | mr | 24 | 5 | 2 | 3 | 2 | 4 | 1 | 1 | 3 | 6.9 | 3.3 | 10.5 | 8.5 | 0.3 | 2.6 | 1.13 |
| Jon Adkins | SD | mr | 28 | 6 | 3 | 4 | 4 | 0 | 1 | 2 | 6 | 8.5 | 2.6 | 11.6 | 5.1 | 0.6 | 2.0 | 1.23 |
| Jeremy Affeldt* |   | mr | 27 | 3 | 4 | 5 | 3 | 2 | 0 | 4 | 8 | 9.1 | 4.0 | 13.3 | 4.7 | 1.3 | 1.2 | 1.45 |
| Matt Albers | Hou | sp | 23 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.3 | 5.3 | 10.5 | 7.5 | 0.8 | 1.4 | 1.17 |
| Antonio Alfonseca | Tex | mr | 34 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 10.4 | 4.2 | 14.5 | 4.2 | 1.0 | 1.0 | 1.62 |
| Steve Andrade | KC | mr | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 9.0 | 18.0 | 0.0 | 0.0 | 0.0 | 2.00 |
| Greg Aquino | Ari | mr | 28 | 6 | 3 | 1 | 1 | 3 | 0 | 8 | 3 | 9.7 | 4.3 | 14.1 | 9.2 | 1.5 | 2.1 | 1.55 |
| Tony Armas | Was | sp | 28 | 4 | 4 | 3 | 19 | 4 | 1 | 9 | 4 | 10.1 | 3.3 | 14.5 | 6.7 | 1.3 | 2.1 | 1.48 |
| Bronson Arroyo | Cin | sp | 29 | 7 | 4 | 7 | 7 | 4 | 0 | 10 | 8 | 7.3 | 2.9 | 10.5 | 6.9 | 1.1 | 2.4 | 1.13 |
| Miguel Asencio | Col | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.3 | 9.0 | 29.3 | 2.3 | 2.3 | 0.3 | 3.25 |
| Ezequiel Astacio | Hou | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19.3 | 3.9 | 23.1 | 11.6 | 3.9 | 3.0 | 2.57 |
| Pedro Astacio | Was | sp | 36 | 7 | 0 | 7 | 1 | 0 | 2 | 7 | 4 | 12.0 | 3.1 | 15.3 | 3.7 | 1.6 | 1.2 | 1.68 |
| Brandon Backe | Hou | sp | 28 | 0 | 0 | 2 | 6 | 4 | 0 | 2 | 3 | 11.5 | 4.5 | 17.4 | 4.5 | 0.5 | 1.0 | 1.78 |
| Cha Seung Baek | Sea | sp | 26 | 1 | 2 | 1 | 4 | 1 | 0 | 1 | 0 | 9.6 | 3.9 | 14.7 | 5.7 | 2.1 | 1.5 | 1.50 |
| Danys Baez |   | mr | 28 | 9 | 1 | 2 | 5 | 4 | 0 | 2 | 3 | 9.0 | 2.4 | 12.1 | 6.1 | 0.9 | 2.5 | 1.27 |
| Jeff Bajenaru | Ari | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.0 | 12.0 | 15.0 | 3.0 | 0.0 | 0.3 | 1.67 |
| Scott Baker | Min | sp | 24 | 11 | 1 | 3 | 2 | 0 | 0 | 1 | 3 | 11.9 | 2.3 | 14.5 | 6.8 | 1.7 | 2.9 | 1.58 |
| Brian Bannister | NYN | sp | 25 | 12 | 0 | 0 | 1 | 2 | 0 | 1 | 2 | 7.7 | 6.1 | 14.1 | 5.5 | 1.3 | 0.9 | 1.54 |
| Kevin Barry | Atl | mr | 27 | 5 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 12.6 | 5.4 | 18.9 | 4.5 | 0.4 | 0.8 | 2.00 |
| Miguel Batista | Ari | sp | 35 | 14 | 8 | 7 | 5 | 10 | 0 | 7 | 5 | 11.8 | 3.7 | 15.8 | 4.8 | 1.3 | 1.3 | 1.73 |
| Rick Bauer | Tex | mr | 29 | 4 | 2 | 0 | 5 | 3 | 0 | 3 | 1 | 7.9 | 2.9 | 11.3 | 3.9 | 0.4 | 1.3 | 1.20 |
| Denny Bautista |   | mr | 23 | 5 | 3 | 0 | 4 | 4 | 0 | 0 | 4 | 11.8 | 3.1 | 15.9 | 4.8 | 1.4 | 1.5 | 1.66 |
| Jonah Bayliss | Pit | mr | 25 | 3 | 1 | 0 | 3 | 7 | 1 | 1 | 1 | 7.9 | 6.4 | 15.2 | 10.0 | 0.0 | 1.6 | 1.58 |
| T.J. Beam | NYA | mr | 25 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 14.6 | 2.9 | 19.7 | 8.0 | 4.4 | 2.8 | 1.95 |
| Josh Beckett | Bos | sp | 26 | 12 | 7 | 1 | 15 | 8 | 1 | 1 | 5 | 8.2 | 2.6 | 11.6 | 6.7 | 1.5 | 2.6 | 1.21 |
| Erik Bedard* | Bal | sp | 27 | 8 | 5 | 5 | 6 | 9 | 0 | 4 | 4 | 9.7 | 3.5 | 13.5 | 8.3 | 1.0 | 2.4 | 1.47 |
| Joe Beimel* | LAN | mr | 29 | 4 | 2 | 7 | 4 | 8 | 1 | 4 | 2 | 11.0 | 5.0 | 16.4 | 3.8 | 1.8 | 0.8 | 1.77 |
| Matt Belisle | Cin | mr | 26 | 3 | 1 | 0 | 2 | 1 | 0 | 4 | 1 | 8.9 | 3.9 | 13.1 | 4.2 | 0.9 | 1.1 | 1.42 |
| Heath Bell | NYN | mr | 28 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 4 | 16.3 | 3.1 | 19.3 | 6.4 | 2.5 | 2.1 | 2.15 |
| Armando Benitez | SF | cl | 33 | 4 | 1 | 1 | 0 | 3 | 0 | 0 | 5 | 11.6 | 4.1 | 15.7 | 7.3 | 1.5 | 1.8 | 1.74 |
| Joaquin Benoit | Tex | mr | 28 | 3 | 0 | 0 | 4 | 1 | 0 | 3 | 3 | 8.4 | 3.7 | 12.5 | 9.4 | 1.1 | 2.5 | 1.34 |
| Kris Benson | Bal | sp | 31 | 12 | 0 | 8 | 6 | 9 | 0 | 5 | 9 | 9.2 | 3.1 | 12.7 | 4.5 | 1.6 | 1.4 | 1.37 |
| Jason Bergmann | Was | mr | 24 | 7 | 2 | 5 | 10 | 5 | 0 | 5 | 5 | 9.4 | 3.3 | 13.8 | 7.1 | 1.5 | 2.1 | 1.41 |
| Adam Bernero |   | sp | 29 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.8 | 1.8 | 12.3 | 8.6 | 1.8 | 4.7 | 1.30 |
| Rafael Betancourt | Cle | mr | 31 | 10 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 7.0 | 0.9 | 8.1 | 6.8 | 0.6 | 7.3 | 0.89 |
| Chad Billingsley | LAN | sp | 21 | 8 | 2 | 3 | 1 | 6 | 0 | 7 | 0 | 8.3 | 5.7 | 14.1 | 6.0 | 1.0 | 1.1 | 1.56 |
| Kurt Birkins* | Bal | mr | 25 | 0 | 0 | 0 | 3 | 4 | 0 | 1 | 1 | 5.0 | 3.9 | 9.5 | 8.0 | 0.4 | 2.1 | 0.98 |
| Joe Blanton | Oak | sp | 25 | 9 | 4 | 4 | 7 | 3 | 0 | 4 | 7 | 9.3 | 2.6 | 12.3 | 5.5 | 0.4 | 2.1 | 1.33 |
| Jeremy Bonderman | Det | sp | 23 | 16 | 1 | 1 | 6 | 4 | 2 | 4 | 3 | 9.0 | 2.3 | 11.6 | 8.0 | 0.7 | 3.5 | 1.26 |
| Boof Bonser | Min | sp | 24 | 4 | 6 | 0 | 2 | 1 | 0 | 2 | 2 | 11.2 | 1.7 | 13.1 | 7.2 | 2.3 | 4.3 | 1.43 |
| Chris Booker |   | mr | 29 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 7.0 | 1.0 | 8.0 | 4.5 | 1.5 | 4.5 | 0.89 |
| Chris Bootcheck | LAA | mr | 27 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 1 | 12.1 | 8.3 | 20.4 | 8.8 | 2.8 | 1.1 | 2.27 |
| Dave Borkowski | Hou | mr | 29 | 2 | 0 | 5 | 0 | 2 | 0 | 2 | 3 | 9.4 | 2.3 | 11.8 | 7.0 | 1.1 | 3.0 | 1.31 |
| Joe Borowski | Flo | cl | 35 | 8 | 1 | 0 | 2 | 1 | 0 | 0 | 2 | 9.6 | 3.4 | 13.2 | 7.8 | 0.4 | 2.3 | 1.45 |
| Micah Bowie* | Was | mr | 31 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.5 | 5.2 | 12.6 | 2.9 | 0.0 | 0.6 | 1.40 |
| Chad Bradford | NYN | mr | 31 | 1 | 1 | 3 | 0 | 0 | 0 | 4 | 2 | 8.1 | 1.3 | 9.4 | 7.4 | 0.1 | 5.6 | 1.04 |
| Ryan Braun | KC | mr | 25 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 13.5 | 4.9 | 18.4 | 7.4 | 1.2 | 1.5 | 2.05 |
| Bill Bray* |   | mr | 23 | 3 | 1 | 4 | 1 | 0 | 0 | 1 | 1 | 10.6 | 4.3 | 15.1 | 7.0 | 0.8 | 1.6 | 1.66 |
| Dewon Brazelton | SD | mr | 26 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 1 | 12.9 | 4.1 | 17.0 | 4.7 | 3.5 | 1.1 | 1.89 |
| Craig Breslow* | Bos | mr | 25 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 7.4 | 6.1 | 16.0 | 6.1 | 0.0 | 1.0 | 1.50 |
| Eude Brito* | Phi | mr | 27 | 4 | 0 | 2 | 1 | 1 | 0 | 0 | 0 | 19.8 | 10.8 | 32.4 | 9.0 | 1.8 | 0.8 | 3.40 |
| Chris Britton | Bal | mr | 23 | 4 | 2 | 5 | 0 | 1 | 1 | 2 | 2 | 9.0 | 2.3 | 11.3 | 6.8 | 0.9 | 3.0 | 1.25 |
| Doug Brocail | SD | mr | 39 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 9.4 | 4.4 | 14.4 | 5.0 | 0.0 | 1.1 | 1.53 |
| Jim Brower |   | mr | 33 | 0 | 0 | 0 | 3 | 2 | 0 | 0 | 3 | 17.6 | 7.6 | 27.0 | 2.9 | 1.2 | 0.4 | 2.80 |
| Andrew Brown | Cle | mr | 25 | 1 | 0 | 1 | 1 | 4 | 0 | 0 | 2 | 7.8 | 4.8 | 13.1 | 4.8 | 0.9 | 1.0 | 1.40 |
| Jonathan Broxton | LAN | mr | 22 | 2 | 0 | 4 | 3 | 1 | 0 | 2 | 2 | 8.1 | 2.9 | 11.3 | 12.2 | 1.7 | 4.3 | 1.22 |
| Brian Bruney | NYA | mr | 24 | 0 | 1 | 0 | 0 | 2 | 0 | 1 | 2 | 9.3 | 12.5 | 21.8 | 12.5 | 0.0 | 1.0 | 2.42 |
| Taylor Buchholz | Hou | sp | 24 | 7 | 2 | 3 | 3 | 3 | 0 | 4 | 4 | 10.2 | 2.7 | 13.2 | 4.9 | 2.2 | 1.8 | 1.43 |
| Mark Buehrle* | ChA | sp | 27 | 9 | 7 | 10 | 11 | 0 | 1 | 5 | 5 | 12.0 | 2.7 | 15.3 | 4.6 | 1.6 | 1.7 | 1.63 |
| Ambiorix Burgos | KC | cl | 22 | 4 | 8 | 6 | 9 | 14 | 1 | 2 | 8 | 10.2 | 4.9 | 16.0 | 8.0 | 2.1 | 1.6 | 1.69 |
| A.J. Burnett | Tor | sp | 29 | 16 | 6 | 2 | 6 | 8 | 2 | 3 | 5 | 11.8 | 3.3 | 15.6 | 6.9 | 1.1 | 2.1 | 1.68 |
| Mike Burns |   | mr | 27 | 0 | 0 | 0 | 1 | 3 | 1 | 0 | 0 | 24.8 | 5.0 | 30.3 | 5.5 | 1.7 | 1.1 | 3.31 |
| Brian Burres* | Bal | mr | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 8.1 | 2.7 | 10.8 | 2.7 | 0.0 | 1.0 | 1.20 |
| Dave Bush | Mil | sp | 26 | 16 | 11 | 7 | 20 | 3 | 0 | 7 | 8 | 8.3 | 1.6 | 10.8 | 7.6 | 1.6 | 4.7 | 1.11 |
| Paul Byrd | Cle | sp | 35 | 5 | 3 | 4 | 6 | 3 | 0 | 8 | 2 | 10.3 | 1.6 | 12.2 | 3.7 | 1.3 | 2.3 | 1.32 |
| Tim Byrdak* | Bal | mr | 32 | 0 | 0 | 3 | 2 | 4 | 0 | 0 | 0 | 20.3 | 13.5 | 35.7 | 5.8 | 2.9 | 0.4 | 3.75 |
| Daniel Cabrera | Bal | sp | 25 | 8 | 3 | 0 | 3 | 16 | 2 | 2 | 7 | 7.5 | 5.9 | 13.6 | 8.8 | 0.7 | 1.5 | 1.49 |
| Fernando Cabrera | Cle | mr | 24 | 4 | 3 | 1 | 1 | 4 | 0 | 2 | 3 | 9.6 | 4.5 | 14.2 | 10.4 | 2.4 | 2.3 | 1.56 |
| Matt Cain | SF | sp | 21 | 14 | 5 | 3 | 3 | 7 | 2 | 9 | 3 | 6.9 | 3.6 | 10.7 | 8.9 | 0.6 | 2.5 | 1.17 |
| Kiko Calero | Oak | mr | 31 | 1 | 5 | 8 | 0 | 0 | 0 | 5 | 3 | 9.6 | 4.0 | 13.6 | 10.7 | 1.1 | 2.7 | 1.51 |
| Shawn Camp | Tam | mr | 30 | 7 | 4 | 6 | 10 | 6 | 0 | 2 | 7 | 16.0 | 2.7 | 19.7 | 5.8 | 1.0 | 2.1 | 2.08 |
| Jose Capellan | Mil | mr | 25 | 4 | 2 | 1 | 0 | 0 | 0 | 2 | 2 | 8.2 | 3.3 | 11.5 | 7.5 | 1.5 | 2.2 | 1.28 |
| Matt Capps | Pit | mr | 22 | 4 | 3 | 5 | 6 | 4 | 0 | 4 | 3 | 7.7 | 1.1 | 9.2 | 6.8 | 0.5 | 6.2 | 0.97 |
| Chris Capuano* | Mil | sp | 27 | 7 | 2 | 10 | 9 | 7 | 0 | 8 | 8 | 9.8 | 2.1 | 12.2 | 7.0 | 1.1 | 3.4 | 1.31 |
| Fausto Carmona | Cle | mr | 22 | 7 | 2 | 3 | 5 | 3 | 1 | 5 | 3 | 12.1 | 2.8 | 15.5 | 6.3 | 1.0 | 2.3 | 1.65 |
| Chris Carpenter | StL | sp | 31 | 4 | 4 | 1 | 6 | 1 | 0 | 12 | 5 | 9.1 | 1.9 | 11.2 | 7.5 | 1.3 | 4.0 | 1.22 |
| Giovanni Carrara | LAN | mr | 38 | 4 | 1 | 0 | 0 | 1 | 0 | 2 | 1 | 9.7 | 3.7 | 13.3 | 6.7 | 3.3 | 1.8 | 1.48 |
| Hector Carrasco | LAA | mr | 36 | 3 | 4 | 1 | 4 | 7 | 0 | 2 | 6 | 8.4 | 2.5 | 11.2 | 6.3 | 0.9 | 2.5 | 1.21 |
| Lance Carter | LAN | mr | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.8 | 2.7 | 13.5 | 2.7 | 0.0 | 1.0 | 1.50 |
| Santiago Casilla | Oak | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 18.0 | 0.0 | 99.0 | 1.00 |
| Scott Cassidy | SD | mr | 30 | 2 | 1 | 0 | 0 | 0 | 0 | 2 | 1 | 11.1 | 2.3 | 13.4 | 13.4 | 2.5 | 5.9 | 1.49 |
| Fabio Castro* |   | mr | 21 | 5 | 1 | 4 | 5 | 1 | 4 | 0 | 1 | 5.3 | 3.5 | 9.6 | 5.3 | 0.4 | 1.5 | 0.97 |
| Gustavo Chacin* | Tor | sp | 25 | 7 | 2 | 3 | 6 | 0 | 0 | 0 | 3 | 8.5 | 4.0 | 13.2 | 6.8 | 1.9 | 1.7 | 1.40 |
| Shawn Chacon |   | sp | 28 | 8 | 4 | 6 | 11 | 6 | 2 | 4 | 3 | 9.9 | 5.6 | 16.6 | 5.7 | 1.9 | 1.0 | 1.72 |
| Bruce Chen* | Bal | mr | 29 | 11 | 4 | 2 | 3 | 1 | 0 | 1 | 5 | 12.1 | 2.9 | 15.3 | 6.7 | 3.0 | 2.3 | 1.67 |
| Jason Childers | Tam | mr | 31 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 15.3 | 7.0 | 22.3 | 4.7 | 1.2 | 0.7 | 2.48 |
| Randy Choate* | Ari | mr | 30 | 0 | 1 | 0 | 7 | 1 | 0 | 2 | 0 | 13.3 | 1.2 | 17.3 | 4.4 | 0.4 | 3.7 | 1.61 |
| Vinnie Chulk |   | mr | 27 | 4 | 1 | 1 | 3 | 5 | 0 | 1 | 1 | 8.2 | 4.0 | 12.8 | 8.8 | 1.8 | 2.2 | 1.36 |
| Brandon Claussen* | Cin | sp | 27 | 9 | 1 | 5 | 4 | 3 | 0 | 7 | 4 | 12.8 | 6.3 | 19.6 | 8.1 | 1.8 | 1.3 | 2.12 |
| Roger Clemens | Hou | sp | 43 | 7 | 2 | 2 | 3 | 0 | 0 | 2 | 0 | 6.0 | 2.4 | 8.6 | 8.1 | 0.8 | 3.4 | 0.93 |
| Matt Clement | Bos | sp | 31 | 3 | 3 | 1 | 4 | 2 | 0 | 1 | 2 | 8.8 | 4.9 | 14.2 | 6.1 | 0.9 | 1.2 | 1.52 |
| Todd Coffey | Cin | mr | 25 | 3 | 2 | 8 | 6 | 4 | 0 | 3 | 3 | 10.1 | 2.7 | 13.3 | 5.9 | 1.1 | 2.2 | 1.42 |
| Bartolo Colon | LAA | sp | 33 | 0 | 1 | 1 | 3 | 2 | 0 | 3 | 0 | 10.0 | 1.2 | 11.7 | 6.2 | 1.7 | 5.0 | 1.25 |
| Roman Colon | Det | mr | 26 | 0 | 1 | 2 | 0 | 6 | 0 | 1 | 3 | 8.5 | 3.6 | 12.1 | 6.6 | 1.1 | 1.8 | 1.35 |
| Clay Condrey | Phi | mr | 30 | 4 | 0 | 4 | 1 | 1 | 0 | 1 | 2 | 11.7 | 3.0 | 15.0 | 4.2 | 1.2 | 1.4 | 1.63 |
| Jose Contreras | ChA | sp | 34 | 18 | 3 | 5 | 15 | 8 | 0 | 2 | 5 | 9.4 | 2.2 | 12.4 | 6.5 | 1.0 | 3.0 | 1.29 |
| Aaron Cook | Col | sp | 27 | 7 | 6 | 13 | 2 | 2 | 0 | 8 | 3 | 10.8 | 2.2 | 13.2 | 3.6 | 0.8 | 1.6 | 1.45 |
| Roy Corcoran | Was | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 1.5 | 15.0 | 1.5 | 1.5 | 1.0 | 1.67 |
| Tim Corcoran | Tam | sp | 28 | 8 | 8 | 1 | 4 | 0 | 1 | 2 | 1 | 9.0 | 5.1 | 14.5 | 5.1 | 0.8 | 1.0 | 1.57 |
| Chad Cordero | Was | cl | 24 | 5 | 4 | 1 | 1 | 0 | 0 | 2 | 3 | 7.9 | 2.4 | 10.4 | 8.1 | 1.6 | 3.3 | 1.14 |
| Francisco Cordero |   | cl | 31 | 4 | 4 | 4 | 5 | 2 | 0 | 0 | 3 | 7.5 | 3.2 | 11.1 | 10.9 | 1.1 | 3.4 | 1.19 |
| Bryan Corey |   | mr | 32 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 12.1 | 3.4 | 15.5 | 6.8 | 0.0 | 2.0 | 1.72 |
| Lance Cormier | Atl | mr | 25 | 7 | 2 | 1 | 2 | 5 | 0 | 6 | 4 | 11.4 | 4.9 | 16.6 | 4.5 | 1.0 | 0.9 | 1.81 |
| Rheal Cormier* |   | mr | 39 | 0 | 0 | 2 | 4 | 4 | 0 | 2 | 2 | 8.3 | 3.4 | 12.4 | 1.9 | 1.3 | 0.5 | 1.31 |
| Manuel Corpas | Col | mr | 23 | 2 | 1 | 0 | 2 | 2 | 0 | 1 | 1 | 13.7 | 1.7 | 16.1 | 8.2 | 0.3 | 4.8 | 1.71 |
| Kevin Correia | SF | mr | 25 | 2 | 0 | 3 | 2 | 0 | 0 | 2 | 6 | 7.8 | 3.7 | 11.7 | 7.7 | 0.7 | 2.1 | 1.27 |
| David Cortes | Col | mr | 32 | 3 | 2 | 0 | 2 | 0 | 0 | 3 | 3 | 11.7 | 1.6 | 13.7 | 5.2 | 0.6 | 3.3 | 1.48 |
| Neal Cotts* | ChA | mr | 26 | 3 | 1 | 13 | 3 | 1 | 0 | 2 | 2 | 7.3 | 4.9 | 12.5 | 6.5 | 1.4 | 1.3 | 1.36 |
| Jesse Crain | Min | mr | 24 | 2 | 2 | 2 | 3 | 0 | 0 | 2 | 3 | 6.8 | 2.3 | 9.5 | 6.8 | 0.5 | 2.9 | 1.01 |
| Francisco Cruceta | Sea | mr | 24 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 12.6 | 3.6 | 16.2 | 7.2 | 1.8 | 2.0 | 1.80 |
| Juan Cruz | Ari | mr | 27 | 7 | 3 | 1 | 13 | 0 | 0 | 6 | 4 | 7.1 | 4.2 | 12.3 | 7.9 | 0.5 | 1.9 | 1.26 |
| Casey Daigle | Ari | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 2.6 | 11.6 | 3.9 | 0.0 | 1.5 | 1.29 |
| Kyle Davies | Atl | sp | 22 | 10 | 1 | 3 | 3 | 5 | 0 | 3 | 3 | 11.7 | 6.0 | 18.2 | 6.8 | 1.6 | 1.1 | 1.97 |
| Doug Davis* | Mil | sp | 30 | 17 | 5 | 2 | 5 | 3 | 0 | 13 | 4 | 9.2 | 4.6 | 14.1 | 7.4 | 1.0 | 1.6 | 1.54 |
| Jason Davis | Cle | mr | 26 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 10.0 | 2.0 | 12.2 | 6.0 | 0.3 | 2.9 | 1.34 |
| Zach Day |   | sp | 28 | 6 | 3 | 0 | 2 | 0 | 0 | 0 | 1 | 12.4 | 1.8 | 14.6 | 3.4 | 0.7 | 1.9 | 1.57 |
| Jorge De La Rosa* |   | mr | 25 | 9 | 3 | 3 | 1 | 4 | 1 | 3 | 3 | 12.1 | 7.6 | 19.8 | 7.5 | 1.8 | 1.0 | 2.19 |
| Manny Delcarmen | Bos | mr | 24 | 2 | 1 | 1 | 1 | 0 | 0 | 2 | 1 | 10.4 | 2.9 | 13.5 | 6.9 | 0.7 | 2.4 | 1.48 |
| Chris Demaria | Mil | mr | 25 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 10.1 | 5.9 | 16.0 | 9.3 | 3.4 | 1.6 | 1.78 |
| Ryan Dempster | ChN | cl | 29 | 5 | 3 | 2 | 3 | 7 | 0 | 3 | 3 | 8.3 | 3.1 | 11.7 | 7.0 | 0.7 | 2.3 | 1.26 |
| Elmer Dessens |   | mr | 35 | 0 | 3 | 1 | 3 | 0 | 0 | 0 | 1 | 7.9 | 1.7 | 10.0 | 5.5 | 0.8 | 3.3 | 1.06 |
| Joey Devine | Atl | mr | 22 | 1 | 0 | 0 | 2 | 2 | 0 | 1 | 1 | 6.2 | 8.3 | 16.6 | 11.4 | 0.0 | 1.4 | 1.62 |
| R.A. Dickey | Tex | sp | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.4 | 1.3 | 7.7 | 3.9 | 3.9 | 3.0 | 0.86 |
| Lenny DiNardo* | Bos | mr | 26 | 3 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 11.0 | 4.7 | 16.0 | 3.4 | 1.1 | 0.7 | 1.75 |
| Scott Dohmann |   | mr | 28 | 4 | 2 | 7 | 3 | 4 | 0 | 2 | 1 | 10.5 | 6.4 | 17.6 | 7.9 | 1.8 | 1.2 | 1.88 |
| Brendan Donnelly | LAA | mr | 34 | 0 | 3 | 1 | 4 | 7 | 0 | 2 | 3 | 5.5 | 3.6 | 9.6 | 6.6 | 1.0 | 1.8 | 1.02 |
| Octavio Dotel | NYA | mr | 32 | 0 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 30.4 | 13.5 | 47.3 | 3.4 | 3.4 | 0.3 | 4.88 |
| Scott Downs* | Tor | mr | 30 | 4 | 1 | 4 | 3 | 4 | 0 | 2 | 2 | 7.2 | 3.4 | 10.8 | 7.4 | 0.8 | 2.2 | 1.17 |
| Ryan Drese | Was | sp | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 2 | 12.7 | 14.3 | 27.0 | 4.8 | 0.0 | 0.3 | 3.00 |
| Justin Duchscherer | Oak | mr | 28 | 3 | 0 | 2 | 1 | 3 | 0 | 0 | 2 | 7.0 | 2.1 | 9.2 | 9.0 | 0.4 | 4.4 | 1.01 |
| Brandon Duckworth | KC | sp | 30 | 3 | 4 | 0 | 2 | 3 | 0 | 1 | 1 | 12.5 | 2.7 | 15.7 | 4.8 | 1.1 | 1.8 | 1.69 |
| Zach Duke* | Pit | sp | 23 | 10 | 9 | 2 | 4 | 5 | 0 | 10 | 1 | 9.9 | 3.5 | 13.5 | 4.7 | 0.7 | 1.4 | 1.48 |
| Scott Dunn | Tam | mr | 28 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 13.5 | 2.5 | 16.9 | 1.7 | 0.0 | 0.7 | 1.78 |
| Chad Durbin | Det | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 7.4 | 2.5 | 9.8 | 4.9 | 0.0 | 2.0 | 1.09 |
| Adam Eaton | Tex | sp | 28 | 1 | 6 | 2 | 3 | 0 | 0 | 2 | 2 | 12.5 | 3.0 | 15.9 | 6.6 | 1.5 | 2.2 | 1.72 |
| Joey Eischen* | Was | mr | 36 | 3 | 0 | 2 | 0 | 1 | 0 | 2 | 0 | 8.5 | 9.0 | 17.5 | 9.0 | 0.0 | 1.0 | 1.94 |
| Scott Elarton | KC | sp | 30 | 2 | 4 | 2 | 9 | 2 | 0 | 5 | 7 | 9.4 | 4.0 | 14.2 | 4.5 | 1.6 | 1.1 | 1.50 |
| Alan Embree* | SD | mr | 36 | 6 | 3 | 5 | 2 | 0 | 0 | 3 | 0 | 8.6 | 3.2 | 12.1 | 10.4 | 0.6 | 3.3 | 1.31 |
| Scott Erickson | NYA | mr | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 9.0 | 0.0 | 99.0 | 1.00 |
| Kelvim Escobar | LAA | sp | 30 | 9 | 3 | 0 | 6 | 6 | 0 | 5 | 6 | 8.8 | 2.3 | 11.3 | 6.6 | 0.7 | 2.9 | 1.22 |
| Shawn Estes* | SD | sp | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.0 | 0.0 | 8.0 | 3.0 | 0.0 | 99.0 | 0.89 |
| Seth Etherton | KC | sp | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 17.6 | 4.7 | 22.3 | 4.7 | 3.5 | 1.0 | 2.48 |
| Dana Eveland* | Mil | sp | 22 | 4 | 1 | 0 | 0 | 0 | 0 | 2 | 0 | 7.7 | 3.1 | 10.7 | 11.0 | 1.5 | 3.6 | 1.19 |
| Scott Eyre* | ChN | mr | 34 | 6 | 1 | 1 | 1 | 2 | 2 | 5 | 4 | 9.0 | 3.9 | 13.0 | 10.8 | 1.9 | 2.8 | 1.43 |
| Willie Eyre | Min | mr | 27 | 2 | 2 | 6 | 7 | 4 | 0 | 1 | 5 | 11.3 | 3.4 | 15.5 | 3.2 | 1.2 | 1.0 | 1.63 |
| Brian Falkenborg | StL | mr | 28 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 9.0 | 3.9 | 14.1 | 3.9 | 0.0 | 1.0 | 1.43 |
| Kyle Farnsworth | NYA | mr | 30 | 5 | 4 | 4 | 1 | 8 | 3 | 1 | 3 | 9.4 | 4.1 | 13.7 | 8.2 | 1.2 | 2.0 | 1.51 |
| Jeff Fassero* | SF | mr | 43 | 0 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 13.2 | 6.6 | 19.8 | 6.6 | 3.3 | 1.0 | 2.20 |
| Ryan Feierabend* | Sea | sp | 20 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 5.1 | 3.9 | 9.0 | 6.4 | 0.6 | 1.7 | 1.00 |
| Scott Feldman | Tex | mr | 23 | 1 | 1 | 0 | 6 | 0 | 0 | 0 | 2 | 10.4 | 2.3 | 13.7 | 6.0 | 1.0 | 2.6 | 1.42 |
| Pedro Feliciano* | NYN | mr | 29 | 3 | 3 | 3 | 5 | 1 | 0 | 4 | 0 | 9.7 | 4.6 | 14.9 | 6.8 | 0.9 | 1.5 | 1.59 |
| Nate Field | Col | mr | 30 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 10.5 | 4.5 | 15.0 | 10.5 | 1.5 | 2.3 | 1.67 |
| Randy Flores* | StL | mr | 30 | 5 | 2 | 6 | 7 | 3 | 0 | 1 | 4 | 8.2 | 3.9 | 13.1 | 8.4 | 1.5 | 2.1 | 1.35 |
| Ron Flores* | Oak | mr | 26 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 7.9 | 2.7 | 10.6 | 6.8 | 0.8 | 2.5 | 1.18 |
| Gavin Floyd | Phi | sp | 23 | 7 | 3 | 3 | 5 | 0 | 0 | 6 | 1 | 12.0 | 6.1 | 19.2 | 4.8 | 2.4 | 0.8 | 2.01 |
| Josh Fogg | Col | sp | 29 | 11 | 7 | 10 | 1 | 3 | 0 | 6 | 13 | 12.3 | 3.1 | 15.4 | 4.1 | 1.4 | 1.3 | 1.71 |
| Casey Fossum* | Tam | sp | 28 | 6 | 3 | 2 | 17 | 5 | 2 | 5 | 2 | 9.9 | 3.3 | 14.4 | 5.8 | 1.3 | 1.7 | 1.46 |
| Keith Foulke | Bos | mr | 33 | 0 | 1 | 3 | 4 | 1 | 0 | 2 | 0 | 8.6 | 1.1 | 10.3 | 6.3 | 1.9 | 5.5 | 1.09 |
| Jeff Francis* | Col | sp | 25 | 19 | 3 | 20 | 13 | 0 | 0 | 5 | 7 | 8.8 | 2.5 | 12.0 | 5.5 | 0.6 | 2.2 | 1.26 |
| Frank Francisco | Tex | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.3 | 2.3 | 22.5 | 6.8 | 4.5 | 3.0 | 2.50 |
| Ryan Franklin |   | mr | 33 | 6 | 1 | 1 | 11 | 2 | 0 | 2 | 3 | 10.2 | 2.2 | 13.7 | 5.0 | 1.1 | 2.2 | 1.39 |
| Wayne Franklin* | Atl | mr | 32 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.5 | 12.3 | 17.2 | 2.5 | 0.0 | 0.2 | 1.64 |
| Jason Frasor | Tor | mr | 28 | 4 | 0 | 2 | 2 | 4 | 0 | 1 | 0 | 8.9 | 3.7 | 12.8 | 9.7 | 2.1 | 2.6 | 1.40 |
| Emiliano Fruto | Sea | mr | 22 | 4 | 1 | 0 | 1 | 2 | 0 | 2 | 1 | 10.0 | 6.0 | 16.2 | 9.4 | 1.4 | 1.6 | 1.78 |
| Brian Fuentes* | Col | cl | 30 | 1 | 1 | 6 | 6 | 11 | 0 | 4 | 4 | 6.9 | 4.9 | 12.4 | 9.7 | 1.2 | 2.0 | 1.31 |
| Aaron Fultz* | Phi | mr | 32 | 11 | 3 | 12 | 5 | 5 | 0 | 1 | 1 | 12.2 | 4.4 | 17.1 | 7.7 | 0.9 | 1.8 | 1.83 |
| Kason Gabbard* | Bos | sp | 24 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5.8 | 5.5 | 11.3 | 5.1 | 0.0 | 0.9 | 1.25 |
| Mike Gallo* | Hou | mr | 28 | 1 | 0 | 0 | 3 | 4 | 0 | 1 | 0 | 18.0 | 6.2 | 26.3 | 6.2 | 1.4 | 1.0 | 2.69 |
| Freddy Garcia | ChA | sp | 30 | 15 | 5 | 4 | 7 | 3 | 0 | 7 | 8 | 8.5 | 2.0 | 10.8 | 5.1 | 1.2 | 2.5 | 1.17 |
| Jose Garcia | Flo | mr | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 3.0 | 9.0 | 1.5 | 0.0 | 0.5 | 1.00 |
| Jon Garland | ChA | sp | 26 | 12 | 2 | 2 | 7 | 3 | 0 | 5 | 7 | 11.4 | 1.9 | 13.7 | 4.7 | 1.2 | 2.5 | 1.48 |
| Matt Garza | Min | sp | 22 | 3 | 1 | 0 | 1 | 2 | 0 | 1 | 2 | 10.5 | 4.2 | 14.9 | 6.0 | 1.4 | 1.4 | 1.63 |
| Chad Gaudin | Oak | mr | 23 | 3 | 4 | 2 | 3 | 2 | 0 | 3 | 1 | 8.8 | 6.2 | 15.5 | 4.6 | 0.8 | 0.7 | 1.66 |
| Geoff Geary | Phi | mr | 29 | 4 | 1 | 17 | 6 | 2 | 0 | 7 | 4 | 9.6 | 2.8 | 13.0 | 6.4 | 0.4 | 2.2 | 1.38 |
| Franklyn German | Flo | mr | 26 | 1 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 7.2 | 4.2 | 11.8 | 5.1 | 0.4 | 1.2 | 1.27 |
| Justin Germano | Cin | sp | 23 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 3.6 | 0.0 | 7.2 | 7.2 | 3.6 | 99.0 | 0.40 |
| Tom Glavine* | NYN | sp | 40 | 6 | 6 | 7 | 8 | 0 | 0 | 9 | 6 | 10.7 | 2.8 | 14.0 | 6.0 | 0.8 | 2.2 | 1.51 |
| Jimmy Gobble* | KC | mr | 24 | 8 | 4 | 1 | 4 | 5 | 0 | 4 | 3 | 8.6 | 4.0 | 13.1 | 8.4 | 1.3 | 2.1 | 1.41 |
| Edgar Gonzalez | Ari | mr | 23 | 1 | 1 | 2 | 4 | 2 | 0 | 0 | 3 | 10.0 | 1.3 | 11.9 | 5.9 | 1.6 | 4.6 | 1.25 |
| Enrique Gonzalez | Ari | sp | 23 | 1 | 3 | 0 | 2 | 1 | 0 | 3 | 4 | 8.2 | 2.2 | 10.6 | 5.9 | 0.8 | 2.6 | 1.16 |
| Geremi Gonzalez |   | mr | 31 | 7 | 1 | 5 | 2 | 0 | 0 | 3 | 1 | 11.1 | 3.0 | 14.4 | 8.3 | 1.2 | 2.7 | 1.57 |
| Mike Gonzalez* | Pit | cl | 28 | 6 | 0 | 2 | 4 | 0 | 0 | 2 | 1 | 6.9 | 5.1 | 12.5 | 10.4 | 0.4 | 2.0 | 1.33 |
| Tom Gordon | Phi | cl | 38 | 5 | 1 | 3 | 4 | 2 | 0 | 2 | 3 | 9.1 | 3.9 | 13.6 | 9.8 | 2.3 | 2.5 | 1.45 |
| Tom Gorzelanny* | Pit | sp | 23 | 5 | 3 | 1 | 3 | 3 | 0 | 6 | 4 | 7.7 | 4.3 | 12.4 | 6.3 | 0.6 | 1.5 | 1.33 |
| Mike Gosling* | Cin | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 0.0 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| John Grabow* | Pit | mr | 27 | 6 | 1 | 4 | 2 | 0 | 0 | 3 | 2 | 8.3 | 3.5 | 12.0 | 9.0 | 1.2 | 2.6 | 1.31 |
| Danny Graves | Cle | mr | 32 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 10.6 | 3.5 | 14.1 | 0.0 | 1.2 | 0.0 | 1.57 |
| Sean Green | Sea | mr | 27 | 0 | 2 | 1 | 2 | 4 | 0 | 2 | 0 | 7.2 | 4.0 | 11.6 | 3.1 | 0.4 | 0.8 | 1.25 |
| Kevin Gregg | LAA | mr | 28 | 13 | 1 | 2 | 0 | 6 | 0 | 1 | 5 | 11.4 | 3.0 | 14.4 | 9.4 | 2.1 | 3.2 | 1.60 |
| Jason Grilli | Det | mr | 29 | 3 | 2 | 3 | 8 | 8 | 0 | 1 | 3 | 10.1 | 4.4 | 15.5 | 3.6 | 0.4 | 0.8 | 1.61 |
| Jason Grimsley | Ari | mr | 38 | 0 | 0 | 0 | 3 | 0 | 0 | 4 | 2 | 10.3 | 2.7 | 13.7 | 3.7 | 1.7 | 1.4 | 1.45 |
| Kevin Gryboski | Was | mr | 32 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 21.9 | 3.4 | 27.0 | 11.8 | 3.4 | 3.5 | 2.81 |
| Eddie Guardado* |   | cl | 35 | 1 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 10.2 | 4.7 | 15.2 | 10.7 | 2.1 | 2.3 | 1.66 |
| Matt Guerrier | Min | mr | 27 | 2 | 1 | 7 | 1 | 11 | 0 | 2 | 2 | 10.5 | 3.3 | 13.9 | 5.0 | 0.9 | 1.5 | 1.53 |
| Jeremy Guthrie | Cle | mr | 27 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 12.0 | 5.0 | 18.0 | 6.5 | 0.5 | 1.3 | 1.89 |
| Angel Guzman | ChN | sp | 24 | 8 | 1 | 2 | 2 | 6 | 0 | 0 | 2 | 12.8 | 5.4 | 18.5 | 9.3 | 2.5 | 1.7 | 2.02 |
| Charlie Haeger | ChA | mr | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 13.5 | 8.7 | 22.2 | 7.9 | 0.0 | 0.9 | 2.47 |
| John Halama* | Bal | mr | 34 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 10.2 | 3.7 | 14.2 | 4.0 | 1.7 | 1.1 | 1.55 |
| Roy Halladay | Tor | sp | 29 | 24 | 2 | 7 | 6 | 1 | 0 | 2 | 1 | 8.1 | 2.0 | 10.4 | 5.2 | 1.0 | 2.6 | 1.12 |
| Brad Halsey* | Oak | mr | 25 | 10 | 4 | 5 | 3 | 8 | 0 | 0 | 4 | 8.8 | 3.9 | 13.0 | 5.4 | 0.6 | 1.4 | 1.41 |
| Cole Hamels* | Phi | sp | 22 | 12 | 4 | 9 | 2 | 8 | 0 | 6 | 6 | 7.5 | 3.7 | 11.3 | 10.2 | 1.1 | 2.8 | 1.24 |
| Jason Hammel | Tam | sp | 23 | 2 | 4 | 2 | 2 | 2 | 2 | 3 | 0 | 11.7 | 4.6 | 16.8 | 6.3 | 0.7 | 1.4 | 1.81 |
| Chris Hammond* | Cin | mr | 40 | 1 | 0 | 3 | 1 | 3 | 0 | 0 | 1 | 8.8 | 3.8 | 12.9 | 8.1 | 0.5 | 2.1 | 1.41 |
| Justin Hampson* | Col | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.4 | 4.0 | 9.4 | 4.0 | 0.0 | 1.0 | 1.05 |
| Tim Hamulack* | LAN | mr | 29 | 1 | 0 | 0 | 3 | 2 | 1 | 2 | 1 | 10.4 | 4.4 | 15.5 | 9.3 | 1.5 | 2.1 | 1.65 |
| Josh Hancock | StL | mr | 28 | 1 | 6 | 1 | 4 | 3 | 1 | 2 | 3 | 8.6 | 3.0 | 12.1 | 5.9 | 1.0 | 2.0 | 1.29 |
| Devern Hansack | Bos | sp | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.9 | 3.3 | 8.2 | 7.4 | 1.6 | 2.3 | 0.91 |
| Craig Hansen | Bos | mr | 22 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 9.8 | 3.5 | 13.3 | 6.3 | 2.0 | 1.8 | 1.48 |
| Aaron Harang | Cin | sp | 28 | 8 | 2 | 3 | 8 | 3 | 1 | 10 | 6 | 9.3 | 2.3 | 12.0 | 8.8 | 1.2 | 3.8 | 1.29 |
| Rich Harden | Oak | sp | 24 | 2 | 3 | 0 | 1 | 1 | 0 | 0 | 0 | 5.4 | 4.4 | 10.0 | 9.0 | 0.3 | 2.0 | 1.09 |
| Dan Haren | Oak | sp | 25 | 11 | 4 | 10 | 11 | 5 | 0 | 5 | 2 | 8.6 | 1.9 | 11.1 | 6.9 | 1.4 | 3.6 | 1.18 |
| Travis Harper | Tam | mr | 30 | 0 | 0 | 1 | 2 | 2 | 1 | 1 | 2 | 10.9 | 2.1 | 13.3 | 6.8 | 1.3 | 3.3 | 1.44 |
| Chad Harville | Tam | mr | 29 | 2 | 0 | 1 | 0 | 4 | 0 | 0 | 1 | 7.9 | 3.5 | 11.4 | 7.7 | 1.2 | 2.2 | 1.26 |
| LaTroy Hawkins | Bal | mr | 33 | 3 | 6 | 5 | 1 | 3 | 0 | 1 | 5 | 8.9 | 3.3 | 12.3 | 3.7 | 0.4 | 1.1 | 1.35 |
| Aaron Heilman | NYN | mr | 27 | 3 | 0 | 3 | 2 | 2 | 0 | 8 | 6 | 9.2 | 2.5 | 11.9 | 7.5 | 0.9 | 3.0 | 1.31 |
| Rick Helling | Mil | mr | 35 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.7 | 2.7 | 8.8 | 9.8 | 0.3 | 3.6 | 0.94 |
| Ben Hendrickson | Mil | sp | 25 | 6 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 9.0 | 11.7 | 20.7 | 5.4 | 0.0 | 0.5 | 2.30 |
| Mark Hendrickson* |   | sp | 32 | 10 | 3 | 2 | 5 | 5 | 2 | 7 | 9 | 8.2 | 3.7 | 12.1 | 4.7 | 0.7 | 1.3 | 1.32 |
| Sean Henn* | NYA | mr | 25 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 10.8 | 5.4 | 16.2 | 5.4 | 1.8 | 1.0 | 1.80 |
| Brad Hennessey | SF | mr | 26 | 9 | 5 | 1 | 11 | 3 | 0 | 4 | 5 | 9.4 | 3.5 | 13.9 | 4.0 | 1.4 | 1.1 | 1.44 |
| Clay Hensley | SD | sp | 26 | 9 | 6 | 4 | 7 | 3 | 0 | 6 | 4 | 9.2 | 4.4 | 14.0 | 5.8 | 0.7 | 1.3 | 1.52 |
| Matt Herges | Flo | mr | 36 | 5 | 3 | 1 | 7 | 1 | 0 | 2 | 5 | 12.5 | 2.5 | 15.9 | 5.3 | 0.7 | 2.2 | 1.67 |
| Dustin Hermanson | ChA | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.1 | 2.1 | 4.2 | 4.2 | 2.1 | 2.0 | 0.46 |
| Felix Hernandez | Sea | sp | 20 | 15 | 7 | 6 | 6 | 9 | 0 | 5 | 3 | 9.2 | 2.5 | 12.0 | 8.1 | 1.2 | 3.3 | 1.30 |
| Livan Hernandez |   | sp | 31 | 30 | 4 | 12 | 3 | 1 | 0 | 12 | 6 | 10.4 | 3.1 | 13.7 | 6.0 | 0.8 | 1.9 | 1.51 |
| Orlando Hernandez |   | sp | 36 | 11 | 5 | 9 | 8 | 3 | 3 | 10 | 8 | 7.8 | 3.5 | 11.8 | 8.9 | 1.2 | 2.5 | 1.26 |
| Roberto Hernandez |   | mr | 41 | 8 | 4 | 5 | 1 | 4 | 0 | 4 | 2 | 8.6 | 3.4 | 12.1 | 6.0 | 0.6 | 1.8 | 1.33 |
| Runelvys Hernandez | KC | sp | 28 | 1 | 3 | 1 | 7 | 3 | 3 | 4 | 2 | 12.0 | 4.3 | 16.9 | 3.6 | 1.9 | 0.8 | 1.81 |
| Rich Hill* | ChN | sp | 26 | 9 | 1 | 3 | 3 | 1 | 0 | 4 | 3 | 7.1 | 3.5 | 10.8 | 8.1 | 1.0 | 2.3 | 1.17 |
| Shawn Hill | Was | sp | 25 | 0 | 1 | 2 | 3 | 2 | 0 | 2 | 0 | 9.8 | 3.9 | 14.4 | 3.9 | 0.5 | 1.0 | 1.51 |
| Jason Hirsh | Hou | sp | 24 | 1 | 1 | 1 | 1 | 4 | 0 | 2 | 3 | 8.2 | 3.8 | 12.2 | 5.7 | 2.1 | 1.5 | 1.34 |
| James Hoey | Bal | mr | 23 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 10.2 | 6.6 | 18.0 | 4.8 | 1.2 | 0.7 | 1.87 |
| Trevor Hoffman | SD | cl | 38 | 1 | 1 | 2 | 0 | 0 | 0 | 1 | 3 | 7.5 | 1.8 | 9.3 | 7.2 | 1.2 | 4.1 | 1.03 |
| J.P. Howell* | Tam | sp | 23 | 3 | 2 | 0 | 3 | 4 | 0 | 2 | 1 | 10.7 | 3.6 | 15.0 | 7.3 | 1.1 | 2.0 | 1.59 |
| Bob Howry | ChN | mr | 32 | 5 | 6 | 1 | 7 | 0 | 0 | 5 | 7 | 8.6 | 1.9 | 11.0 | 7.7 | 0.7 | 4.1 | 1.16 |
| Jon Huber | Sea | mr | 24 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 8.2 | 3.7 | 11.9 | 2.9 | 1.2 | 0.8 | 1.32 |
| Luke Hudson | KC | sp | 29 | 5 | 5 | 0 | 6 | 7 | 0 | 5 | 5 | 12.0 | 3.3 | 15.7 | 5.4 | 0.7 | 1.7 | 1.69 |
| Tim Hudson | Atl | sp | 30 | 19 | 4 | 3 | 4 | 3 | 0 | 9 | 10 | 9.1 | 2.6 | 11.8 | 5.2 | 0.8 | 2.0 | 1.30 |
| Travis Hughes | Was | mr | 28 | 2 | 0 | 0 | 8 | 2 | 0 | 0 | 1 | 21.1 | 6.6 | 32.9 | 3.3 | 3.3 | 0.5 | 3.07 |
| Jason Isringhausen | StL | cl | 33 | 3 | 2 | 2 | 4 | 2 | 0 | 3 | 4 | 10.4 | 8.8 | 19.9 | 7.6 | 2.0 | 0.9 | 2.14 |
| Edwin Jackson | Tam | mr | 22 | 1 | 1 | 0 | 1 | 2 | 2 | 2 | 1 | 10.1 | 5.5 | 15.8 | 7.6 | 0.3 | 1.4 | 1.73 |
| Zach Jackson* | Mil | sp | 23 | 5 | 0 | 0 | 0 | 2 | 0 | 1 | 2 | 10.7 | 3.6 | 14.3 | 6.1 | 1.4 | 1.7 | 1.59 |
| Chuck James* | Atl | sp | 24 | 13 | 5 | 6 | 8 | 1 | 0 | 5 | 5 | 8.8 | 4.7 | 14.1 | 7.2 | 1.8 | 1.5 | 1.50 |
| Casey Janssen | Tor | sp | 24 | 4 | 2 | 2 | 6 | 4 | 2 | 5 | 1 | 10.6 | 2.3 | 13.5 | 3.4 | 2.5 | 1.5 | 1.43 |
| Kevin Jarvis |   | mr | 36 | 2 | 1 | 0 | 3 | 0 | 0 | 2 | 2 | 11.8 | 2.8 | 15.6 | 5.2 | 0.7 | 1.9 | 1.62 |
| Bobby Jenks | ChA | cl | 25 | 9 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 8.3 | 2.1 | 10.6 | 11.2 | 0.4 | 5.2 | 1.16 |
| Jason Jennings | Col | sp | 27 | 14 | 6 | 4 | 3 | 10 | 0 | 8 | 4 | 8.4 | 4.0 | 12.5 | 6.5 | 0.7 | 1.6 | 1.38 |
| Cesar Jimenez* | Sea | mr | 21 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 27.0 | 5.4 | 32.4 | 0.0 | 16.2 | 0.0 | 3.60 |
| Ubaldo Jimenez | Col | sp | 22 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 12.0 | 3.0 | 15.0 | 9.0 | 0.0 | 3.0 | 1.67 |
| Jason Johnson |   | mr | 32 | 8 | 3 | 1 | 2 | 6 | 0 | 2 | 4 | 12.4 | 3.3 | 15.9 | 4.4 | 1.0 | 1.3 | 1.74 |
| Jim Johnson | Bal | sp | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 20.3 | 47.3 | 0.0 | 6.8 | 0.0 | 5.25 |
| Josh Johnson | Flo | sp | 22 | 11 | 2 | 5 | 6 | 3 | 2 | 5 | 2 | 9.6 | 3.5 | 13.5 | 9.2 | 1.1 | 2.6 | 1.46 |
| Randy Johnson* | NYA | sp | 42 | 15 | 4 | 10 | 6 | 4 | 1 | 6 | 4 | 8.0 | 2.9 | 11.2 | 7.8 | 0.9 | 2.7 | 1.21 |
| Tyler Johnson* | StL | mr | 25 | 5 | 0 | 2 | 6 | 4 | 0 | 2 | 1 | 10.2 | 5.9 | 17.6 | 10.4 | 1.2 | 1.8 | 1.79 |
| Greg Jones | LAA | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 4.5 | 31.5 | 0.0 | 0.0 | 0.0 | 3.50 |
| Todd Jones | Det | cl | 38 | 1 | 1 | 2 | 4 | 5 | 0 | 1 | 3 | 10.0 | 1.0 | 11.7 | 4.9 | 0.8 | 5.0 | 1.23 |
| Jorge Julio |   | cl | 27 | 5 | 4 | 0 | 3 | 6 | 0 | 3 | 4 | 7.7 | 5.5 | 13.7 | 11.1 | 1.1 | 2.0 | 1.47 |
| Steve Karsay | Oak | mr | 34 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 7.8 | 2.4 | 10.8 | 2.4 | 2.4 | 1.0 | 1.13 |
| Jeff Karstens | NYA | sp | 23 | 1 | 0 | 3 | 1 | 4 | 1 | 0 | 0 | 8.3 | 2.0 | 10.5 | 4.2 | 1.1 | 2.1 | 1.14 |
| Scott Kazmir* | Tam | sp | 22 | 7 | 4 | 5 | 4 | 4 | 0 | 4 | 0 | 8.0 | 4.4 | 12.6 | 12.0 | 0.8 | 2.7 | 1.37 |
| Randy Keisler* | Oak | mr | 30 | 1 | 1 | 3 | 0 | 1 | 0 | 0 | 0 | 14.3 | 6.4 | 20.6 | 4.0 | 3.2 | 0.6 | 2.29 |
| Joe Kennedy* | Oak | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 10.2 | 2.8 | 13.2 | 7.7 | 0.3 | 2.8 | 1.44 |
| Logan Kensing | Flo | mr | 23 | 3 | 0 | 0 | 3 | 1 | 0 | 1 | 2 | 10.2 | 3.9 | 14.7 | 11.4 | 3.0 | 2.9 | 1.56 |
| Bobby Keppel | KC | sp | 24 | 1 | 0 | 3 | 1 | 1 | 0 | 0 | 1 | 12.3 | 4.0 | 16.6 | 4.6 | 1.8 | 1.2 | 1.81 |
| Byung-Hyun Kim | Col | sp | 27 | 19 | 7 | 14 | 4 | 4 | 0 | 9 | 5 | 10.5 | 3.6 | 14.3 | 6.9 | 0.9 | 1.9 | 1.57 |
| Sun-Woo Kim |   | mr | 28 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 10.4 | 3.7 | 14.1 | 5.5 | 1.8 | 1.5 | 1.57 |
| Ray King* | Col | mr | 32 | 0 | 0 | 8 | 3 | 7 | 0 | 3 | 0 | 12.1 | 5.3 | 17.8 | 5.0 | 0.8 | 1.0 | 1.93 |
| Josh Kinney | StL | mr | 27 | 1 | 0 | 0 | 0 | 1 | 0 | 3 | 0 | 6.4 | 4.1 | 10.5 | 6.7 | 1.0 | 1.6 | 1.16 |
| Steve Kline* | SF | mr | 33 | 2 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 11.4 | 4.7 | 16.1 | 7.2 | 0.4 | 1.5 | 1.79 |
| Dan Kolb | Mil | mr | 31 | 1 | 3 | 2 | 3 | 9 | 0 | 7 | 7 | 10.5 | 3.9 | 14.7 | 5.1 | 0.8 | 1.3 | 1.60 |
| Shane Komine | Oak | sp | 25 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 9.0 | 5.0 | 14.0 | 2.0 | 4.0 | 0.4 | 1.56 |
| John Koronka* | Tex | sp | 25 | 12 | 1 | 1 | 3 | 4 | 2 | 7 | 3 | 11.7 | 2.6 | 14.5 | 5.2 | 1.2 | 2.0 | 1.59 |
| Hong-Chih Kuo* | LAN | mr | 24 | 9 | 2 | 1 | 0 | 0 | 0 | 3 | 2 | 7.6 | 2.8 | 10.5 | 11.1 | 0.5 | 3.9 | 1.16 |
| John Lackey | LAA | sp | 27 | 10 | 4 | 1 | 7 | 11 | 0 | 4 | 4 | 9.0 | 3.2 | 12.5 | 7.8 | 1.1 | 2.4 | 1.36 |
| Juan Lara* | Cle | mr | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 7.7 | 7.7 | 11.6 | 0.0 | 1.5 | 0.86 |
| Brandon League | Tor | mr | 23 | 1 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 5.3 | 1.1 | 7.2 | 7.4 | 1.3 | 6.5 | 0.72 |
| Wilfredo Ledezma* | Det | mr | 25 | 4 | 1 | 1 | 2 | 2 | 0 | 0 | 2 | 11.1 | 2.3 | 13.7 | 5.3 | 1.4 | 2.3 | 1.48 |
| Cliff Lee* | Cle | sp | 27 | 13 | 6 | 8 | 1 | 2 | 0 | 2 | 5 | 11.0 | 2.8 | 13.8 | 5.8 | 1.1 | 2.1 | 1.53 |
| Justin Lehr | Mil | mr | 28 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 12.3 | 2.5 | 14.7 | 4.9 | 0.0 | 2.0 | 1.64 |
| Jon Lester* | Bos | sp | 22 | 3 | 1 | 0 | 1 | 1 | 0 | 3 | 4 | 9.8 | 4.2 | 14.1 | 7.6 | 0.6 | 1.8 | 1.56 |
| Colby Lewis | Det | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 4.5 | 9.0 | 0.0 | 0.0 | 0.0 | 1.00 |
| Brad Lidge | Hou | cl | 29 | 9 | 0 | 6 | 2 | 9 | 0 | 0 | 1 | 7.1 | 4.2 | 11.5 | 14.1 | 1.3 | 3.4 | 1.25 |
| Cory Lidle |   | sp | 34 | 5 | 4 | 7 | 5 | 4 | 0 | 4 | 5 | 9.6 | 3.5 | 13.4 | 6.1 | 1.6 | 1.7 | 1.45 |
| Jon Lieber | Phi | sp | 36 | 1 | 2 | 3 | 2 | 1 | 0 | 10 | 3 | 12.0 | 1.2 | 13.3 | 5.3 | 1.6 | 4.3 | 1.47 |
| Ted Lilly* | Tor | sp | 30 | 19 | 2 | 10 | 3 | 7 | 5 | 4 | 9 | 10.0 | 4.7 | 14.8 | 7.9 | 1.3 | 1.7 | 1.63 |
| Jose Lima | NYN | sp | 33 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 15.3 | 1.5 | 16.8 | 6.6 | 2.2 | 4.5 | 1.86 |
| Scott Linebrink | SD | mr | 29 | 14 | 2 | 1 | 2 | 1 | 0 | 4 | 6 | 10.8 | 2.4 | 13.4 | 6.9 | 1.1 | 2.8 | 1.47 |
| Francisco Liriano* | Min | sp | 22 | 8 | 5 | 3 | 1 | 9 | 0 | 2 | 4 | 5.4 | 3.0 | 8.5 | 11.1 | 0.6 | 3.7 | 0.93 |
| Wes Littleton | Tex | mr | 23 | 2 | 1 | 4 | 5 | 0 | 0 | 1 | 1 | 6.9 | 3.7 | 11.6 | 5.2 | 0.6 | 1.4 | 1.18 |
| Esteban Loaiza | Oak | sp | 34 | 5 | 3 | 10 | 6 | 3 | 0 | 3 | 4 | 8.5 | 2.6 | 11.4 | 5.2 | 0.8 | 2.0 | 1.23 |
| Kameron Loe | Tex | sp | 24 | 4 | 5 | 0 | 1 | 2 | 0 | 1 | 3 | 11.1 | 2.4 | 13.6 | 3.1 | 1.3 | 1.3 | 1.49 |
| Adam Loewen* | Bal | sp | 22 | 4 | 6 | 0 | 5 | 0 | 0 | 5 | 4 | 7.9 | 5.0 | 13.3 | 8.9 | 0.3 | 1.8 | 1.43 |
| Boone Logan* | ChA | mr | 21 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 7.1 | 3.2 | 11.9 | 9.1 | 0.0 | 2.9 | 1.15 |
| Kyle Lohse |   | sp | 27 | 4 | 1 | 1 | 4 | 3 | 1 | 5 | 4 | 11.1 | 2.7 | 14.1 | 7.3 | 1.0 | 2.7 | 1.54 |
| Braden Looper | StL | mr | 31 | 6 | 2 | 3 | 8 | 0 | 0 | 4 | 5 | 9.2 | 2.8 | 12.7 | 4.7 | 0.5 | 1.7 | 1.34 |
| Javier Lopez* | Bos | mr | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4.2 | 3.5 | 7.7 | 7.1 | 0.6 | 2.0 | 0.86 |
| Rodrigo Lopez | Bal | sp | 30 | 11 | 5 | 3 | 4 | 3 | 4 | 7 | 3 | 10.5 | 2.5 | 13.2 | 7.1 | 1.5 | 2.8 | 1.44 |
| Derek Lowe | LAN | sp | 33 | 16 | 7 | 5 | 7 | 3 | 2 | 7 | 4 | 9.6 | 2.6 | 12.5 | 5.5 | 0.8 | 2.1 | 1.35 |
| Mark Lowe | Sea | mr | 23 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6.8 | 2.9 | 9.6 | 9.6 | 0.0 | 3.3 | 1.07 |
| Noah Lowry* | SF | sp | 25 | 10 | 5 | 3 | 4 | 1 | 1 | 13 | 6 | 9.7 | 3.1 | 13.0 | 5.7 | 1.3 | 1.9 | 1.42 |
| Ruddy Lugo | Tam | mr | 26 | 4 | 4 | 2 | 7 | 8 | 0 | 4 | 0 | 8.9 | 3.9 | 13.4 | 4.3 | 0.6 | 1.1 | 1.42 |
| Brandon Lyon | Ari | mr | 26 | 3 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 10.2 | 2.9 | 13.2 | 6.1 | 1.0 | 2.1 | 1.46 |
| Mike MacDougal |   | mr | 29 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 8.7 | 2.7 | 12.2 | 7.2 | 1.1 | 2.7 | 1.27 |
| Greg Maddux |   | sp | 40 | 17 | 5 | 2 | 2 | 0 | 0 | 14 | 2 | 10.2 | 1.7 | 12.0 | 5.8 | 0.9 | 3.3 | 1.32 |
| Ryan Madson | Phi | mr | 25 | 12 | 4 | 3 | 7 | 11 | 0 | 7 | 8 | 12.5 | 3.6 | 16.7 | 7.5 | 1.2 | 2.1 | 1.79 |
| Ron Mahay* | Tex | mr | 35 | 4 | 1 | 0 | 2 | 3 | 1 | 3 | 0 | 8.9 | 4.8 | 14.0 | 8.8 | 0.7 | 1.8 | 1.52 |
| Paul Maholm* | Pit | sp | 24 | 11 | 6 | 5 | 8 | 2 | 3 | 8 | 8 | 10.0 | 4.5 | 15.0 | 6.1 | 1.0 | 1.4 | 1.61 |
| John Maine | NYN | sp | 25 | 3 | 1 | 0 | 1 | 1 | 0 | 3 | 2 | 5.1 | 3.2 | 8.4 | 8.4 | 0.8 | 2.6 | 0.92 |
| Gary Majewski |   | mr | 26 | 3 | 4 | 2 | 3 | 1 | 0 | 3 | 2 | 9.6 | 3.8 | 13.8 | 5.6 | 0.6 | 1.5 | 1.49 |
| Julio Manon | Bal | mr | 32 | 0 | 1 | 3 | 2 | 1 | 0 | 0 | 2 | 12.6 | 5.4 | 18.6 | 6.3 | 2.7 | 1.2 | 2.00 |
| Shaun Marcum | Tor | sp | 24 | 4 | 2 | 2 | 3 | 1 | 0 | 1 | 6 | 10.1 | 4.5 | 15.0 | 6.1 | 2.3 | 1.3 | 1.62 |
| Carlos Marmol | ChN | sp | 23 | 3 | 1 | 2 | 2 | 3 | 1 | 5 | 4 | 7.1 | 7.0 | 14.3 | 7.0 | 1.2 | 1.0 | 1.56 |
| Mike Maroth* | Det | sp | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 9.8 | 2.5 | 12.3 | 4.5 | 1.4 | 1.8 | 1.36 |
| Jason Marquis | StL | sp | 27 | 8 | 2 | 1 | 10 | 2 | 0 | 7 | 4 | 10.4 | 3.2 | 14.2 | 3.8 | 1.8 | 1.2 | 1.52 |
| Sean Marshall* | ChN | sp | 23 | 6 | 3 | 2 | 7 | 3 | 0 | 7 | 4 | 10.0 | 3.3 | 13.8 | 7.5 | 1.2 | 2.3 | 1.48 |
| Damaso Marte* | Pit | mr | 31 | 8 | 3 | 3 | 2 | 2 | 3 | 6 | 3 | 8.0 | 5.8 | 14.0 | 10.1 | 0.9 | 1.7 | 1.53 |
| Tom Martin* | Col | mr | 36 | 0 | 0 | 1 | 3 | 2 | 0 | 3 | 2 | 10.0 | 3.4 | 13.8 | 6.5 | 0.4 | 1.9 | 1.49 |
| Carlos Martinez | Flo | mr | 24 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.0 | 2.4 | 9.0 | 15.0 | 0.0 | 6.3 | 0.93 |
| Pedro Martinez | NYN | sp | 34 | 11 | 1 | 2 | 8 | 0 | 1 | 6 | 4 | 7.8 | 3.0 | 11.3 | 8.9 | 1.8 | 3.0 | 1.19 |
| Tom Mastny | Cle | cl | 25 | 2 | 1 | 0 | 1 | 4 | 0 | 2 | 2 | 15.7 | 3.3 | 19.3 | 7.3 | 0.7 | 2.2 | 2.11 |
| Juan Mateo | ChN | sp | 23 | 2 | 0 | 2 | 2 | 1 | 0 | 5 | 2 | 11.1 | 4.6 | 16.1 | 5.5 | 1.1 | 1.2 | 1.74 |
| Julio Mateo | Sea | mr | 28 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 2 | 11.1 | 3.6 | 14.7 | 6.0 | 1.2 | 1.7 | 1.63 |
| Scott Mathieson | Phi | sp | 22 | 3 | 1 | 0 | 1 | 2 | 0 | 2 | 1 | 15.9 | 2.6 | 18.9 | 7.8 | 2.9 | 3.0 | 2.06 |
| Joe Mays |   | sp | 30 | 2 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 13.9 | 5.3 | 19.2 | 3.3 | 1.8 | 0.6 | 2.13 |
| Macay McBride* | Atl | mr | 23 | 4 | 0 | 6 | 2 | 2 | 1 | 3 | 1 | 10.9 | 8.8 | 20.1 | 9.2 | 0.5 | 1.0 | 2.20 |
| Brandon McCarthy | ChA | mr | 22 | 10 | 1 | 5 | 3 | 9 | 0 | 2 | 5 | 8.9 | 3.5 | 12.6 | 7.3 | 1.4 | 2.1 | 1.38 |
| Seth McClung | Tam | mr | 25 | 10 | 3 | 1 | 2 | 6 | 0 | 2 | 4 | 10.9 | 6.5 | 17.6 | 5.0 | 1.2 | 0.8 | 1.93 |
| Dustin McGowan | Tor | mr | 24 | 2 | 2 | 1 | 1 | 4 | 3 | 0 | 1 | 9.6 | 4.6 | 14.6 | 8.2 | 0.4 | 1.8 | 1.58 |
| Marty McLeary | Pit | mr | 31 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 12.0 | 8.0 | 21.0 | 5.0 | 0.0 | 0.6 | 2.22 |
| Brian Meadows | Tam | mr | 30 | 2 | 2 | 5 | 1 | 3 | 0 | 3 | 3 | 12.1 | 1.7 | 13.9 | 4.3 | 1.7 | 2.6 | 1.53 |
| Gil Meche | Sea | sp | 27 | 10 | 5 | 1 | 3 | 3 | 2 | 3 | 1 | 9.1 | 4.0 | 13.2 | 6.9 | 1.4 | 1.8 | 1.45 |
| Brandon Medders | Ari | mr | 26 | 5 | 4 | 6 | 3 | 2 | 0 | 2 | 5 | 9.4 | 3.9 | 13.7 | 6.7 | 0.6 | 1.7 | 1.48 |
| Kent Mercker* | Cin | mr | 38 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 8.2 | 4.0 | 12.6 | 5.0 | 0.8 | 1.2 | 1.36 |
| Cla Meredith | SD | mr | 23 | 3 | 0 | 4 | 3 | 0 | 1 | 1 | 0 | 6.4 | 1.1 | 8.1 | 5.5 | 1.1 | 5.0 | 0.83 |
| Jose Mesa | Col | mr | 40 | 1 | 0 | 8 | 7 | 5 | 2 | 4 | 1 | 8.4 | 5.7 | 14.8 | 5.7 | 0.8 | 1.0 | 1.56 |
| Randy Messenger | Flo | mr | 24 | 3 | 1 | 2 | 0 | 2 | 0 | 0 | 0 | 10.4 | 2.8 | 13.2 | 5.8 | 2.5 | 2.1 | 1.46 |
| Dan Miceli | Tam | mr | 35 | 1 | 1 | 0 | 1 | 6 | 0 | 0 | 1 | 4.9 | 4.6 | 9.7 | 5.1 | 0.3 | 1.1 | 1.05 |
| Chris Michalak* | Cin | sp | 35 | 3 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 15.7 | 4.7 | 20.7 | 3.9 | 1.2 | 0.8 | 2.26 |
| Andrew Miller* | Det | mr | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 8.3 | 22.8 | 31.2 | 2.1 | 0.0 | 0.1 | 3.46 |
| Matt Miller | Cle | mr | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 6.8 | 20.3 | 13.5 | 6.8 | 2.0 | 2.25 |
| Trever Miller* | Hou | mr | 33 | 1 | 2 | 2 | 3 | 2 | 0 | 6 | 1 | 7.5 | 2.1 | 10.0 | 10.1 | 1.5 | 4.9 | 1.07 |
| Wade Miller | ChN | sp | 29 | 3 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 8.2 | 7.8 | 16.8 | 7.4 | 0.8 | 0.9 | 1.78 |
| Kevin Millwood | Tex | sp | 31 | 9 | 5 | 1 | 7 | 3 | 0 | 6 | 7 | 10.0 | 1.8 | 12.1 | 6.5 | 0.9 | 3.6 | 1.31 |
| Eric Milton* | Cin | sp | 30 | 6 | 8 | 10 | 2 | 0 | 0 | 6 | 7 | 10.0 | 2.5 | 12.6 | 5.6 | 1.1 | 2.3 | 1.39 |
| Zach Miner | Det | sp | 24 | 4 | 0 | 0 | 1 | 0 | 0 | 3 | 4 | 10.9 | 2.6 | 13.5 | 4.7 | 1.3 | 1.8 | 1.49 |
| Sergio Mitre | Flo | sp | 25 | 3 | 1 | 5 | 6 | 1 | 0 | 5 | 1 | 8.7 | 4.2 | 13.8 | 6.9 | 1.6 | 1.7 | 1.42 |
| Brian Moehler | Flo | sp | 34 | 7 | 5 | 4 | 9 | 2 | 0 | 4 | 5 | 11.6 | 2.9 | 15.2 | 5.1 | 1.4 | 1.8 | 1.61 |
| Agustin Montero | ChA | mr | 28 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 6.0 | 0.4 | 6.9 | 3.0 | 2.1 | 7.0 | 0.71 |
| Juan Morillo | Col | sp | 22 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 14.3 | 6.4 | 20.6 | 4.8 | 1.6 | 0.8 | 2.29 |
| Matt Morris | SF | sp | 31 | 16 | 2 | 3 | 14 | 0 | 4 | 8 | 6 | 9.1 | 2.1 | 11.9 | 5.3 | 1.1 | 2.5 | 1.25 |
| Dustin Moseley | LAA | sp | 24 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 14.7 | 1.2 | 16.0 | 4.9 | 1.2 | 4.0 | 1.77 |
| Guillermo Mota |   | mr | 32 | 2 | 2 | 0 | 1 | 3 | 0 | 1 | 2 | 7.9 | 2.4 | 10.3 | 8.7 | 0.9 | 3.7 | 1.14 |
| Jamie Moyer* |   | sp | 43 | 6 | 5 | 11 | 4 | 4 | 1 | 1 | 9 | 10.0 | 3.0 | 13.2 | 4.2 | 1.8 | 1.4 | 1.44 |
| Peter Moylan | Atl | mr | 27 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 10.3 | 1.1 | 11.4 | 11.0 | 1.1 | 10.3 | 1.26 |
| Edward Mujica | Cle | mr | 22 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 11.6 | 0.0 | 12.1 | 6.8 | 0.5 | 99.0 | 1.29 |
| Mark Mulder* | StL | sp | 28 | 10 | 3 | 6 | 1 | 5 | 0 | 6 | 3 | 12.7 | 4.3 | 17.2 | 4.3 | 2.7 | 1.0 | 1.90 |
| Terry Mulholland* | Ari | mr | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 27.0 | 0.0 | 27.0 | 10.8 | 5.4 | 99.0 | 3.00 |
| Scott Munter | SF | mr | 26 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 2 | 13.7 | 6.2 | 20.4 | 4.9 | 0.9 | 0.8 | 2.21 |
| Mike Mussina | NYA | sp | 37 | 18 | 8 | 3 | 3 | 3 | 0 | 0 | 4 | 8.4 | 2.1 | 10.6 | 8.7 | 0.8 | 4.2 | 1.17 |
| Brett Myers | Phi | sp | 25 | 11 | 5 | 1 | 3 | 0 | 0 | 8 | 6 | 8.1 | 2.9 | 11.1 | 8.6 | 1.4 | 3.0 | 1.22 |
| Mike Myers* | NYA | mr | 37 | 1 | 2 | 1 | 6 | 3 | 0 | 0 | 1 | 9.2 | 3.2 | 13.3 | 5.6 | 0.8 | 1.8 | 1.38 |
| Chris Narveson* | StL | mr | 24 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 9.0 | 11.3 | 20.3 | 18.0 | 0.0 | 1.6 | 2.25 |
| Joe Nathan | Min | cl | 31 | 5 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 6.0 | 1.2 | 7.4 | 14.8 | 1.1 | 12.5 | 0.80 |
| Jeff Nelson | ChA | mr | 39 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.6 | 3.9 | 15.4 | 9.6 | 0.0 | 2.5 | 1.71 |
| Joe Nelson | KC | mr | 31 | 1 | 2 | 2 | 0 | 0 | 0 | 2 | 2 | 9.2 | 5.1 | 14.3 | 9.9 | 1.3 | 2.0 | 1.58 |
| Pat Neshek | Min | mr | 25 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 7.1 | 2.1 | 9.2 | 11.7 | 2.1 | 5.5 | 1.03 |
| Fernando Nieve | Hou | mr | 23 | 2 | 3 | 3 | 4 | 0 | 0 | 4 | 4 | 6.4 | 3.0 | 9.8 | 6.4 | 1.4 | 2.1 | 1.04 |
| Dustin Nippert | Ari | sp | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 21.2 | 5.8 | 27.0 | 7.7 | 9.6 | 1.3 | 3.00 |
| Ricky Nolasco | Flo | sp | 23 | 8 | 3 | 14 | 8 | 8 | 0 | 13 | 8 | 10.3 | 2.9 | 13.8 | 5.7 | 1.1 | 2.0 | 1.47 |
| Roberto Novoa | ChN | mr | 26 | 4 | 2 | 4 | 5 | 6 | 0 | 3 | 5 | 9.7 | 3.8 | 14.1 | 6.6 | 1.3 | 1.7 | 1.51 |
| Leo Nunez | KC | mr | 22 | 1 | 0 | 0 | 3 | 1 | 0 | 1 | 0 | 10.2 | 3.6 | 15.3 | 7.6 | 1.0 | 2.1 | 1.53 |
| Mike O'Connor* | Was | sp | 25 | 11 | 7 | 3 | 3 | 6 | 0 | 3 | 2 | 8.2 | 4.3 | 12.8 | 5.0 | 1.1 | 1.2 | 1.39 |
| Eric O'Flaherty* | Sea | mr | 21 | 1 | 0 | 2 | 0 | 3 | 1 | 2 | 2 | 19.9 | 5.6 | 25.4 | 4.0 | 2.4 | 0.7 | 2.82 |
| Ryan O'Malley* | ChN | sp | 26 | 1 | 0 | 2 | 2 | 1 | 0 | 3 | 1 | 4.4 | 9.5 | 15.3 | 5.1 | 1.5 | 0.5 | 1.54 |
| Tomo Ohka | Mil | sp | 30 | 2 | 4 | 0 | 3 | 7 | 0 | 6 | 1 | 8.2 | 4.0 | 12.4 | 4.4 | 0.8 | 1.1 | 1.35 |
| Will Ohman* | ChN | mr | 28 | 7 | 0 | 3 | 5 | 4 | 0 | 4 | 4 | 7.2 | 6.1 | 13.9 | 8.4 | 1.3 | 1.4 | 1.48 |
| Darren Oliver* | NYN | mr | 35 | 2 | 1 | 3 | 3 | 1 | 0 | 6 | 4 | 6.7 | 2.5 | 9.5 | 6.8 | 1.4 | 2.7 | 1.03 |
| Scott Olsen* | Flo | sp | 22 | 11 | 6 | 8 | 6 | 3 | 0 | 5 | 3 | 8.8 | 3.3 | 12.4 | 7.8 | 1.4 | 2.3 | 1.35 |
| Ramon Ortiz | Was | sp | 33 | 7 | 8 | 5 | 16 | 5 | 1 | 9 | 3 | 11.2 | 3.1 | 15.0 | 5.3 | 1.3 | 1.7 | 1.58 |
| Russ Ortiz |   | sp | 32 | 3 | 2 | 5 | 3 | 0 | 0 | 2 | 5 | 13.8 | 5.4 | 19.6 | 7.3 | 4.2 | 1.3 | 2.13 |
| Chad Orvella | Tam | mr | 25 | 2 | 1 | 1 | 1 | 2 | 0 | 0 | 4 | 12.1 | 6.7 | 19.1 | 6.7 | 1.6 | 1.0 | 2.08 |
| Franquelis Osoria | LAN | mr | 24 | 1 | 0 | 2 | 0 | 3 | 0 | 1 | 1 | 14.4 | 6.8 | 21.1 | 4.9 | 2.3 | 0.7 | 2.35 |
| Roy Oswalt | Hou | sp | 28 | 11 | 5 | 2 | 9 | 0 | 0 | 10 | 4 | 9.2 | 2.2 | 11.7 | 6.1 | 0.6 | 2.8 | 1.26 |
| Akinori Otsuka | Tex | cl | 34 | 3 | 3 | 1 | 1 | 5 | 0 | 3 | 1 | 8.6 | 1.7 | 10.4 | 8.2 | 0.6 | 4.8 | 1.14 |
| Vicente Padilla | Tex | sp | 28 | 14 | 7 | 6 | 14 | 2 | 3 | 2 | 6 | 9.8 | 3.2 | 13.7 | 6.3 | 1.1 | 2.0 | 1.45 |
| Jonathan Papelbon | Bos | cl | 25 | 1 | 1 | 1 | 2 | 1 | 0 | 0 | 4 | 6.5 | 1.7 | 8.5 | 9.9 | 0.8 | 5.7 | 0.92 |
| Chan Ho Park | SD | sp | 33 | 13 | 7 | 4 | 3 | 6 | 0 | 3 | 5 | 12.2 | 2.7 | 15.1 | 6.3 | 1.3 | 2.4 | 1.65 |
| Chad Paronto | Atl | mr | 30 | 4 | 1 | 1 | 1 | 3 | 0 | 3 | 4 | 10.1 | 3.4 | 13.7 | 7.3 | 1.1 | 2.1 | 1.51 |
| John Patterson | Was | sp | 28 | 6 | 2 | 2 | 3 | 0 | 0 | 2 | 1 | 7.6 | 3.1 | 11.3 | 10.5 | 1.0 | 3.4 | 1.19 |
| David Pauley | Bos | sp | 23 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.8 | 2.6 | 17.4 | 3.9 | 0.6 | 1.5 | 1.93 |
| Jake Peavy | SD | sp | 25 | 22 | 4 | 12 | 6 | 5 | 0 | 13 | 8 | 8.3 | 2.9 | 11.4 | 9.3 | 0.9 | 3.3 | 1.24 |
| Mike Pelfrey | NYN | sp | 22 | 1 | 2 | 1 | 2 | 1 | 0 | 0 | 0 | 15.6 | 6.6 | 23.4 | 9.0 | 1.2 | 1.4 | 2.47 |
| Tony Pena | Ari | mr | 24 | 1 | 2 | 3 | 0 | 0 | 0 | 1 | 3 | 11.0 | 4.1 | 15.1 | 6.0 | 2.2 | 1.5 | 1.67 |
| Hayden Penn | Bal | sp | 21 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 22.5 | 6.4 | 29.6 | 2.6 | 5.1 | 0.4 | 3.21 |
| Brad Penny | LAN | sp | 28 | 21 | 10 | 1 | 6 | 5 | 0 | 8 | 4 | 10.1 | 2.1 | 12.5 | 7.0 | 0.9 | 3.3 | 1.36 |
| Joel Peralta | KC | mr | 30 | 2 | 1 | 8 | 3 | 4 | 0 | 0 | 3 | 8.7 | 2.7 | 11.8 | 8.0 | 0.8 | 3.0 | 1.27 |
| Beltran Perez | Was | mr | 24 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.4 | 5.8 | 14.1 | 5.1 | 3.2 | 0.9 | 1.57 |
| Juan Perez* | Pit | mr | 27 | 0 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 18.4 | 8.6 | 31.9 | 4.9 | 1.2 | 0.6 | 3.00 |
| Odalis Perez* |   | mr | 29 | 5 | 5 | 1 | 3 | 10 | 4 | 5 | 5 | 11.9 | 2.7 | 14.8 | 5.0 | 1.4 | 1.8 | 1.62 |
| Oliver Perez* |   | sp | 24 | 3 | 4 | 6 | 10 | 1 | 1 | 6 | 0 | 9.7 | 7.5 | 18.1 | 9.3 | 0.7 | 1.2 | 1.90 |
| Rafael Perez* | Cle | mr | 24 | 2 | 0 | 3 | 1 | 3 | 1 | 0 | 2 | 9.6 | 4.6 | 14.5 | 10.4 | 0.8 | 2.3 | 1.57 |
| Yusmeiro Petit | Flo | mr | 21 | 3 | 0 | 1 | 1 | 1 | 0 | 3 | 1 | 15.8 | 1.1 | 17.2 | 7.8 | 2.5 | 6.8 | 1.88 |
| Andy Pettitte* | Hou | sp | 34 | 12 | 7 | 10 | 8 | 1 | 1 | 13 | 2 | 10.4 | 3.6 | 14.4 | 8.0 | 1.7 | 2.2 | 1.56 |
| Joel Pineiro | Sea | sp | 27 | 8 | 5 | 0 | 9 | 2 | 0 | 2 | 2 | 11.2 | 2.9 | 14.7 | 5.0 | 1.7 | 1.7 | 1.57 |
| Renyel Pinto* | Flo | mr | 23 | 1 | 1 | 3 | 2 | 7 | 0 | 0 | 0 | 9.5 | 9.5 | 19.8 | 13.5 | 0.7 | 1.4 | 2.12 |
| Cliff Politte | ChA | mr | 32 | 3 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 13.3 | 2.5 | 16.2 | 4.9 | 2.9 | 2.0 | 1.75 |
| Sidney Ponson |   | sp | 29 | 3 | 3 | 1 | 4 | 0 | 0 | 3 | 1 | 11.3 | 3.3 | 15.0 | 6.1 | 0.8 | 1.9 | 1.62 |
| Mark Prior | ChN | sp | 25 | 7 | 0 | 3 | 8 | 3 | 0 | 3 | 1 | 7.7 | 4.0 | 13.2 | 7.6 | 2.3 | 1.9 | 1.30 |
| Scott Proctor | NYA | mr | 29 | 5 | 2 | 1 | 5 | 0 | 0 | 1 | 4 | 8.3 | 1.9 | 10.7 | 8.2 | 0.8 | 4.3 | 1.14 |
| J.J. Putz | Sea | cl | 29 | 0 | 1 | 2 | 1 | 2 | 0 | 2 | 1 | 6.0 | 1.4 | 7.6 | 10.5 | 0.2 | 7.5 | 0.83 |
| Chad Qualls | Hou | mr | 27 | 5 | 0 | 1 | 4 | 0 | 0 | 6 | 1 | 8.1 | 2.3 | 10.8 | 6.5 | 1.0 | 2.8 | 1.16 |
| Brad Radke | Min | sp | 33 | 11 | 6 | 0 | 3 | 1 | 0 | 5 | 5 | 12.6 | 1.8 | 14.6 | 5.1 | 1.6 | 2.8 | 1.60 |
| Elizardo Ramirez | Cin | sp | 23 | 3 | 4 | 5 | 8 | 0 | 2 | 5 | 3 | 12.4 | 3.1 | 16.3 | 5.6 | 1.4 | 1.8 | 1.72 |
| Horacio Ramirez* | Atl | sp | 26 | 6 | 3 | 0 | 6 | 0 | 1 | 4 | 3 | 10.8 | 3.0 | 14.5 | 4.7 | 0.6 | 1.6 | 1.53 |
| Ramon Ramirez | Col | mr | 24 | 2 | 1 | 9 | 1 | 2 | 0 | 2 | 2 | 8.8 | 4.2 | 13.2 | 8.7 | 0.7 | 2.1 | 1.45 |
| Darrell Rasner | NYA | sp | 25 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 8.8 | 2.9 | 13.5 | 2.9 | 1.8 | 1.0 | 1.30 |
| Jon Rauch | Was | mr | 27 | 11 | 1 | 6 | 1 | 2 | 0 | 5 | 5 | 8.7 | 5.1 | 13.8 | 8.6 | 1.4 | 1.7 | 1.53 |
| Chris Ray | Bal | cl | 24 | 3 | 1 | 0 | 1 | 2 | 0 | 3 | 2 | 7.1 | 4.4 | 11.6 | 7.2 | 1.8 | 1.6 | 1.28 |
| Ken Ray | Atl | mr | 31 | 4 | 2 | 5 | 2 | 0 | 0 | 3 | 4 | 7.5 | 5.4 | 13.1 | 8.5 | 1.1 | 1.6 | 1.43 |
| Britt Reames | Pit | mr | 32 | 2 | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 15.4 | 6.8 | 22.2 | 5.8 | 2.9 | 0.9 | 2.46 |
| Mark Redman* | KC | sp | 32 | 3 | 3 | 16 | 1 | 6 | 0 | 3 | 2 | 10.2 | 3.7 | 13.9 | 3.6 | 1.0 | 1.0 | 1.54 |
| Chris Reitsma | Atl | cl | 28 | 3 | 2 | 2 | 7 | 1 | 0 | 0 | 5 | 14.5 | 1.4 | 17.5 | 3.9 | 3.0 | 2.8 | 1.77 |
| Mike Remlinger* | Atl | mr | 40 | 0 | 0 | 2 | 4 | 3 | 0 | 1 | 1 | 8.9 | 5.0 | 15.4 | 7.3 | 0.0 | 1.5 | 1.54 |
| Chris Resop | Flo | mr | 23 | 2 | 0 | 1 | 2 | 2 | 0 | 3 | 1 | 10.0 | 4.1 | 14.7 | 5.3 | 0.3 | 1.3 | 1.57 |
| Anthony Reyes | StL | sp | 24 | 5 | 0 | 0 | 6 | 2 | 0 | 5 | 3 | 7.2 | 3.1 | 10.8 | 7.8 | 1.7 | 2.5 | 1.14 |
| Dennys Reyes* | Min | mr | 29 | 1 | 2 | 3 | 1 | 3 | 0 | 1 | 1 | 8.0 | 2.4 | 10.6 | 8.2 | 0.3 | 3.4 | 1.16 |
| John Rheinecker* | Tex | sp | 27 | 3 | 2 | 5 | 2 | 0 | 0 | 1 | 1 | 11.5 | 2.9 | 14.7 | 3.1 | 1.0 | 1.0 | 1.60 |
| Arthur Rhodes* | Phi | mr | 36 | 2 | 1 | 1 | 3 | 13 | 0 | 6 | 3 | 12.0 | 3.4 | 15.8 | 9.9 | 0.6 | 2.9 | 1.71 |
| Juan Rincon | Min | mr | 27 | 5 | 3 | 0 | 5 | 4 | 0 | 4 | 2 | 7.6 | 2.3 | 10.3 | 8.0 | 0.3 | 3.5 | 1.09 |
| Ricardo Rincon* | StL | mr | 36 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 9.6 | 7.7 | 23.1 | 5.8 | 1.9 | 0.8 | 1.93 |
| Royce Ring* | NYN | mr | 25 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 8.8 | 6.6 | 15.3 | 2.2 | 2.9 | 0.3 | 1.70 |
| David Riske |   | mr | 29 | 5 | 4 | 9 | 3 | 0 | 0 | 1 | 2 | 9.4 | 3.7 | 13.5 | 6.2 | 0.6 | 1.7 | 1.45 |
| Mariano Rivera | NYA | cl | 36 | 0 | 1 | 3 | 4 | 0 | 0 | 3 | 4 | 6.8 | 1.2 | 8.4 | 7.4 | 0.5 | 6.2 | 0.89 |
| Saul Rivera | Was | mr | 28 | 6 | 1 | 2 | 4 | 3 | 0 | 2 | 3 | 9.0 | 4.9 | 14.5 | 6.1 | 0.4 | 1.2 | 1.55 |
| Sendy Rleal | Bal | mr | 26 | 5 | 1 | 0 | 2 | 2 | 0 | 1 | 3 | 9.4 | 5.8 | 15.6 | 6.0 | 1.9 | 1.0 | 1.69 |
| Nate Robertson* | Det | sp | 28 | 6 | 5 | 4 | 15 | 2 | 0 | 2 | 2 | 9.5 | 2.5 | 12.7 | 5.0 | 1.3 | 2.0 | 1.33 |
| Fernando Rodney | Det | mr | 29 | 4 | 1 | 3 | 10 | 4 | 0 | 3 | 3 | 7.7 | 3.4 | 12.5 | 8.0 | 1.4 | 2.4 | 1.24 |
| Eddy Rodriguez | Bal | mr | 24 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 12.5 | 4.8 | 17.4 | 3.9 | 2.9 | 0.8 | 1.93 |
| Felix Rodriguez | Was | mr | 33 | 2 | 0 | 3 | 3 | 0 | 0 | 2 | 2 | 7.9 | 7.9 | 17.0 | 5.8 | 1.2 | 0.7 | 1.75 |
| Francisco Rodriguez | LAA | cl | 24 | 4 | 2 | 1 | 0 | 7 | 0 | 1 | 1 | 5.6 | 2.0 | 7.6 | 10.2 | 0.6 | 5.1 | 0.84 |
| Wandy Rodriguez* | Hou | sp | 27 | 10 | 1 | 6 | 3 | 5 | 0 | 4 | 3 | 10.8 | 5.8 | 16.9 | 6.9 | 1.8 | 1.2 | 1.85 |
| Brian Rogers | Pit | mr | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 9.8 | 3.0 | 12.8 | 8.3 | 2.3 | 2.8 | 1.42 |
| Kenny Rogers* | Det | sp | 41 | 6 | 0 | 1 | 11 | 1 | 0 | 2 | 3 | 8.4 | 3.0 | 11.9 | 3.9 | 0.6 | 1.3 | 1.27 |
| Davis Romero* | Tor | mr | 23 | 3 | 0 | 3 | 0 | 1 | 0 | 1 | 0 | 14.4 | 6.6 | 21.0 | 6.0 | 1.2 | 0.9 | 2.33 |
| J.C. Romero* | LAA | mr | 30 | 2 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 11.7 | 4.6 | 16.7 | 5.8 | 0.4 | 1.3 | 1.81 |
| Francisco Rosario | Tor | mr | 25 | 6 | 0 | 4 | 1 | 6 | 0 | 0 | 0 | 12.2 | 6.6 | 19.1 | 8.9 | 3.0 | 1.4 | 2.09 |
| Josh Rupe | Tex | mr | 23 | 2 | 0 | 0 | 4 | 5 | 1 | 0 | 1 | 13.1 | 2.7 | 16.7 | 2.3 | 0.2 | 0.8 | 1.76 |
| Glendon Rusch* | ChN | mr | 31 | 2 | 3 | 0 | 1 | 0 | 0 | 3 | 1 | 10.3 | 5.0 | 15.5 | 9.2 | 3.1 | 1.8 | 1.71 |
| B.J. Ryan* | Tor | cl | 30 | 3 | 2 | 1 | 2 | 7 | 1 | 1 | 0 | 4.1 | 3.4 | 7.7 | 11.3 | 0.1 | 3.3 | 0.83 |
| Jae Kuk Ryu | ChN | mr | 23 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 18.0 | 1.8 | 20.7 | 9.9 | 7.2 | 5.5 | 2.20 |
| Kirk Saarloos | Oak | mr | 27 | 9 | 3 | 4 | 3 | 1 | 0 | 3 | 4 | 10.1 | 3.4 | 13.6 | 3.2 | 1.4 | 1.0 | 1.49 |
| C.C. Sabathia* | Cle | sp | 25 | 8 | 5 | 3 | 4 | 2 | 0 | 5 | 3 | 8.3 | 1.6 | 10.1 | 8.4 | 0.9 | 5.1 | 1.10 |
| Takashi Saito | LAN | cl | 36 | 7 | 2 | 1 | 2 | 1 | 0 | 7 | 4 | 5.2 | 3.5 | 8.9 | 12.3 | 0.4 | 3.5 | 0.96 |
| Juan Salas | Tam | mr | 27 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 14.5 | 6.2 | 20.8 | 4.2 | 1.0 | 0.7 | 2.31 |
| Chris Sampson | Hou | mr | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.0 | 0.9 | 4.9 | 4.2 | 0.5 | 4.5 | 0.55 |
| Brian Sanches | Phi | mr | 27 | 1 | 1 | 2 | 0 | 1 | 0 | 0 | 1 | 9.5 | 3.6 | 13.1 | 8.4 | 1.1 | 2.3 | 1.46 |
| Anibal Sanchez | Flo | sp | 22 | 6 | 2 | 1 | 3 | 1 | 0 | 5 | 6 | 8.7 | 3.2 | 12.1 | 7.1 | 0.8 | 2.2 | 1.32 |
| Duaner Sanchez | NYN | mr | 26 | 2 | 3 | 5 | 4 | 0 | 0 | 2 | 0 | 6.2 | 3.2 | 9.9 | 7.8 | 0.3 | 2.5 | 1.04 |
| Jonathan Sanchez* | SF | mr | 23 | 6 | 0 | 3 | 3 | 0 | 0 | 2 | 3 | 6.5 | 4.1 | 11.2 | 9.6 | 1.0 | 2.4 | 1.17 |
| Ervin Santana | LAA | sp | 23 | 6 | 5 | 1 | 14 | 8 | 2 | 8 | 5 | 8.8 | 2.6 | 12.0 | 6.3 | 1.4 | 2.4 | 1.26 |
| Johan Santana* | Min | sp | 27 | 6 | 1 | 0 | 3 | 6 | 1 | 4 | 4 | 7.3 | 2.2 | 9.5 | 10.5 | 0.8 | 4.9 | 1.05 |
| Julio Santana | Phi | mr | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 9.0 | 0.0 | 99.0 | 0.00 |
| Victor Santos | Pit | sp | 29 | 14 | 1 | 1 | 10 | 4 | 0 | 10 | 5 | 11.8 | 2.7 | 15.2 | 5.7 | 1.2 | 2.1 | 1.61 |
| Dennis Sarfate | Mil | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Scott Sauerbeck* |   | mr | 34 | 4 | 1 | 1 | 13 | 1 | 0 | 2 | 2 | 7.9 | 6.7 | 17.8 | 5.9 | 0.7 | 0.9 | 1.62 |
| Joe Saunders* | LAA | sp | 25 | 2 | 0 | 1 | 2 | 2 | 1 | 1 | 0 | 10.2 | 3.8 | 14.3 | 6.4 | 0.5 | 1.7 | 1.56 |
| Curt Schilling | Bos | sp | 39 | 3 | 4 | 0 | 2 | 0 | 0 | 4 | 4 | 10.8 | 1.1 | 11.9 | 8.2 | 1.5 | 7.5 | 1.32 |
| Jason Schmidt | SF | sp | 33 | 18 | 7 | 2 | 2 | 7 | 2 | 6 | 6 | 8.6 | 2.8 | 11.4 | 8.0 | 1.0 | 2.9 | 1.26 |
| Scott Schoeneweis* |   | mr | 32 | 4 | 0 | 1 | 2 | 7 | 0 | 2 | 3 | 10.1 | 3.4 | 13.8 | 4.9 | 1.3 | 1.4 | 1.50 |
| Chris Schroder | Was | mr | 27 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.5 | 3.6 | 11.4 | 12.1 | 3.2 | 3.4 | 1.22 |
| Rudy Seanez |   | mr | 37 | 6 | 2 | 1 | 1 | 4 | 0 | 2 | 3 | 11.1 | 4.4 | 15.7 | 7.3 | 0.7 | 1.7 | 1.73 |
| Bobby Seay* | Det | mr | 28 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 6.4 | 2.4 | 9.7 | 7.7 | 0.0 | 3.2 | 0.99 |
| Aaron Sele | LAN | sp | 36 | 6 | 2 | 2 | 2 | 1 | 0 | 9 | 4 | 10.4 | 2.8 | 13.3 | 4.2 | 0.9 | 1.5 | 1.46 |
| Jae Seo |   | sp | 29 | 5 | 5 | 2 | 4 | 1 | 1 | 1 | 3 | 12.1 | 3.4 | 15.7 | 5.4 | 2.1 | 1.6 | 1.71 |
| Brian Shackelford* | Cin | mr | 29 | 0 | 1 | 3 | 0 | 1 | 0 | 0 | 1 | 10.3 | 4.4 | 14.7 | 6.9 | 3.4 | 1.6 | 1.64 |
| Josh Sharpless | Pit | mr | 25 | 3 | 1 | 0 | 0 | 1 | 0 | 3 | 1 | 4.7 | 8.3 | 13.0 | 8.3 | 0.0 | 1.0 | 1.44 |
| Ben Sheets | Mil | sp | 27 | 6 | 6 | 1 | 6 | 2 | 0 | 7 | 1 | 8.9 | 1.6 | 11.0 | 10.0 | 1.4 | 6.1 | 1.17 |
| George Sherrill* | Sea | mr | 29 | 5 | 4 | 3 | 1 | 4 | 0 | 1 | 1 | 8.9 | 8.0 | 17.1 | 9.6 | 0.3 | 1.2 | 1.88 |
| James Shields | Tam | sp | 24 | 6 | 2 | 1 | 10 | 3 | 0 | 3 | 4 | 11.7 | 2.9 | 15.3 | 6.9 | 1.3 | 2.4 | 1.62 |
| Scot Shields | LAA | mr | 30 | 11 | 2 | 1 | 2 | 4 | 0 | 3 | 1 | 7.5 | 2.0 | 9.7 | 8.5 | 1.2 | 4.2 | 1.05 |
| Jason Shiell | Atl | sp | 29 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 13.0 | 5.4 | 19.4 | 9.7 | 4.3 | 1.8 | 2.04 |
| Brian Shouse* |   | mr | 37 | 1 | 2 | 3 | 5 | 0 | 0 | 3 | 3 | 9.3 | 3.6 | 13.8 | 4.8 | 1.4 | 1.3 | 1.43 |
| Brian Sikorski |   | mr | 31 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 7.0 | 1.2 | 8.6 | 10.2 | 2.9 | 8.3 | 0.91 |
| Carlos Silva | Min | sp | 27 | 10 | 7 | 0 | 7 | 0 | 0 | 3 | 6 | 13.3 | 1.7 | 15.4 | 3.4 | 2.2 | 2.0 | 1.66 |
| Andrew Sisco* | KC | mr | 23 | 2 | 2 | 1 | 2 | 4 | 0 | 2 | 2 | 11.6 | 5.2 | 17.1 | 7.4 | 0.7 | 1.4 | 1.86 |
| Doug Slaten* | Ari | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.1 | 0.0 | 5.1 | 3.4 | 0.0 | 99.0 | 0.56 |
| Brian Slocum | Cle | mr | 25 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 25.5 | 7.5 | 34.5 | 4.5 | 3.0 | 0.6 | 3.67 |
| Aaron Small | NYA | mr | 34 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.8 | 5.6 | 14.4 | 3.3 | 2.3 | 0.6 | 1.60 |
| Matt Smith* |   | mr | 27 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.3 | 3.7 | 9.4 | 11.0 | 0.5 | 2.9 | 1.01 |
| Mike Smith | Min | sp | 28 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 18.0 | 4.5 | 31.5 | 18.0 | 0.0 | 4.0 | 2.50 |
| Travis Smith | Atl | sp | 33 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 27.0 | 27.0 | 54.0 | 0.0 | 0.0 | 0.0 | 6.00 |
| John Smoltz | Atl | sp | 39 | 16 | 9 | 6 | 8 | 3 | 0 | 6 | 5 | 8.6 | 2.6 | 11.5 | 8.9 | 1.0 | 3.4 | 1.24 |
| Ian Snell | Pit | sp | 24 | 16 | 4 | 4 | 3 | 5 | 0 | 9 | 2 | 10.8 | 3.0 | 13.9 | 8.6 | 1.4 | 2.9 | 1.53 |
| Kyle Snyder |   | sp | 28 | 2 | 1 | 2 | 3 | 3 | 0 | 0 | 3 | 13.7 | 2.3 | 16.4 | 6.9 | 1.9 | 3.0 | 1.78 |
| Alay Soler | NYN | sp | 26 | 6 | 1 | 1 | 1 | 1 | 1 | 3 | 0 | 8.9 | 5.0 | 14.0 | 3.9 | 1.3 | 0.8 | 1.54 |
| Rafael Soriano | Sea | mr | 26 | 5 | 1 | 2 | 4 | 0 | 0 | 2 | 5 | 5.4 | 2.9 | 8.8 | 9.0 | 0.4 | 3.1 | 0.93 |
| Jorge Sosa |   | mr | 29 | 1 | 3 | 7 | 2 | 2 | 0 | 7 | 3 | 9.3 | 2.5 | 11.9 | 4.9 | 1.5 | 2.0 | 1.31 |
| Jeremy Sowers* | Cle | sp | 23 | 5 | 5 | 1 | 3 | 0 | 0 | 0 | 1 | 7.2 | 2.1 | 9.5 | 3.9 | 0.4 | 1.9 | 1.02 |
| Justin Speier | Tor | mr | 32 | 13 | 1 | 0 | 4 | 2 | 0 | 1 | 4 | 6.9 | 2.0 | 9.3 | 9.3 | 1.1 | 4.6 | 0.99 |
| Russ Springer | Hou | mr | 37 | 4 | 0 | 6 | 3 | 1 | 0 | 4 | 1 | 6.9 | 3.2 | 10.4 | 6.8 | 1.5 | 2.1 | 1.12 |
| Chris Spurling |   | mr | 29 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 6.3 | 2.9 | 9.8 | 2.9 | 0.6 | 1.0 | 1.02 |
| Jason Standridge | Cin | mr | 27 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 11.8 | 9.5 | 21.7 | 8.4 | 1.1 | 0.9 | 2.37 |
| Mike Stanton* |   | cl | 39 | 6 | 1 | 11 | 2 | 1 | 1 | 10 | 5 | 9.1 | 3.0 | 12.3 | 6.1 | 0.4 | 2.1 | 1.34 |
| Tim Stauffer | SD | sp | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.4 | 1.3 | 7.7 | 6.4 | 0.0 | 5.0 | 0.86 |
| Steve Stemle | KC | mr | 29 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 19.7 | 5.2 | 24.9 | 5.2 | 1.0 | 1.0 | 2.77 |
| Brian Stokes | Tam | sp | 26 | 0 | 1 | 1 | 2 | 1 | 0 | 0 | 1 | 13.2 | 6.0 | 20.4 | 7.2 | 1.8 | 1.2 | 2.13 |
| Huston Street | Oak | cl | 22 | 2 | 3 | 7 | 0 | 7 | 0 | 3 | 2 | 8.3 | 2.2 | 10.5 | 9.0 | 0.2 | 4.0 | 1.16 |
| Eric Stults* | LAN | mr | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 7.8 | 1.8 | 9.6 | 3.0 | 1.2 | 1.7 | 1.07 |
| Tanyon Sturtze | NYA | mr | 35 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 12.4 | 5.6 | 18.0 | 2.3 | 1.1 | 0.4 | 2.00 |
| Jeff Suppan | StL | sp | 31 | 6 | 7 | 1 | 9 | 4 | 0 | 10 | 4 | 9.1 | 2.8 | 12.4 | 5.2 | 0.9 | 1.9 | 1.33 |
| Brian Sweeney | SD | mr | 32 | 6 | 2 | 5 | 2 | 2 | 1 | 4 | 3 | 9.1 | 4.7 | 14.0 | 3.1 | 0.6 | 0.7 | 1.53 |
| Jon Switzer* | Tam | mr | 26 | 1 | 1 | 4 | 2 | 0 | 0 | 1 | 1 | 9.9 | 5.5 | 15.9 | 4.8 | 0.5 | 0.9 | 1.72 |
| Brian Tallet* | Tor | mr | 28 | 3 | 1 | 1 | 2 | 1 | 2 | 0 | 4 | 6.9 | 4.0 | 11.3 | 6.8 | 0.4 | 1.7 | 1.22 |
| Taylor Tankersley* | Flo | mr | 23 | 5 | 1 | 1 | 1 | 7 | 0 | 1 | 1 | 8.0 | 5.9 | 14.0 | 12.2 | 0.5 | 2.1 | 1.54 |
| Jack Taschner* | SF | mr | 28 | 0 | 0 | 2 | 0 | 1 | 0 | 1 | 1 | 20.3 | 4.7 | 25.0 | 2.7 | 3.4 | 0.6 | 2.77 |
| Jordan Tata | Det | mr | 24 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 1 | 7.6 | 4.6 | 12.2 | 2.0 | 0.0 | 0.4 | 1.35 |
| Ty Taubenheim | Tor | sp | 23 | 2 | 1 | 2 | 2 | 0 | 0 | 1 | 3 | 12.5 | 5.5 | 18.6 | 5.5 | 1.7 | 1.0 | 2.00 |
| Julian Tavarez | Bos | mr | 33 | 2 | 3 | 0 | 7 | 3 | 0 | 1 | 2 | 8.9 | 4.0 | 13.4 | 5.1 | 0.9 | 1.3 | 1.43 |
| Robinson Tejeda | Tex | sp | 24 | 10 | 3 | 6 | 2 | 3 | 1 | 4 | 6 | 9.9 | 5.1 | 15.3 | 4.8 | 1.4 | 0.9 | 1.67 |
| Brad Thompson | StL | mr | 24 | 2 | 1 | 1 | 6 | 1 | 0 | 3 | 0 | 9.2 | 2.8 | 13.1 | 6.1 | 0.7 | 2.2 | 1.34 |
| Mike Thompson | SD | sp | 25 | 8 | 2 | 1 | 4 | 1 | 0 | 5 | 2 | 11.2 | 2.3 | 13.9 | 3.6 | 0.9 | 1.6 | 1.50 |
| John Thomson | Atl | sp | 32 | 8 | 1 | 1 | 0 | 3 | 0 | 9 | 5 | 10.8 | 2.7 | 13.5 | 4.8 | 2.1 | 1.7 | 1.50 |
| Matt Thornton* | ChA | mr | 29 | 3 | 2 | 2 | 0 | 0 | 0 | 1 | 2 | 8.5 | 3.2 | 11.7 | 7.2 | 1.2 | 2.3 | 1.30 |
| Mike Timlin | Bos | mr | 40 | 5 | 1 | 1 | 2 | 3 | 0 | 4 | 5 | 11.6 | 1.4 | 13.2 | 4.5 | 0.6 | 3.3 | 1.44 |
| Brett Tomko | LAN | mr | 33 | 6 | 3 | 0 | 2 | 2 | 0 | 5 | 9 | 9.6 | 1.9 | 11.7 | 7.4 | 1.5 | 3.8 | 1.29 |
| Salomon Torres | Pit | mr | 34 | 4 | 2 | 3 | 7 | 3 | 0 | 4 | 4 | 12.5 | 3.3 | 16.6 | 7.4 | 0.5 | 2.2 | 1.76 |
| Josh Towers | Tor | sp | 29 | 6 | 1 | 1 | 2 | 0 | 1 | 0 | 3 | 13.3 | 3.4 | 17.1 | 5.7 | 2.3 | 1.7 | 1.86 |
| Billy Traber* | Was | sp | 26 | 5 | 2 | 4 | 11 | 1 | 0 | 2 | 1 | 12.6 | 3.8 | 18.9 | 5.2 | 1.2 | 1.4 | 1.82 |
| Sean Tracey | ChA | mr | 25 | 0 | 0 | 2 | 3 | 3 | 0 | 1 | 1 | 6.8 | 7.7 | 17.4 | 4.8 | 0.0 | 0.6 | 1.61 |
| Steve Trachsel | NYN | sp | 35 | 12 | 5 | 0 | 11 | 2 | 0 | 8 | 4 | 10.9 | 4.1 | 15.7 | 4.1 | 1.1 | 1.0 | 1.67 |
| Derrick Turnbow | Mil | cl | 28 | 1 | 3 | 1 | 3 | 5 | 3 | 3 | 2 | 10.7 | 6.7 | 17.9 | 11.9 | 1.7 | 1.8 | 1.93 |
| Jose Valverde | Ari | cl | 26 | 2 | 4 | 2 | 0 | 0 | 0 | 4 | 1 | 9.9 | 5.2 | 15.1 | 11.9 | 1.8 | 2.3 | 1.67 |
| Jermaine Van Buren | Bos | mr | 25 | 1 | 0 | 2 | 0 | 0 | 1 | 0 | 1 | 11.7 | 11.0 | 22.7 | 7.4 | 0.0 | 0.7 | 2.52 |
| Claudio Vargas | Ari | sp | 28 | 5 | 2 | 0 | 3 | 6 | 4 | 8 | 5 | 10.3 | 2.9 | 13.4 | 5.6 | 1.6 | 1.9 | 1.47 |
| Jason Vargas* | Flo | mr | 23 | 1 | 2 | 3 | 2 | 3 | 0 | 1 | 1 | 11.1 | 4.5 | 16.1 | 8.1 | 1.9 | 1.8 | 1.74 |
| Javier Vazquez | ChA | sp | 29 | 10 | 4 | 4 | 14 | 8 | 0 | 5 | 2 | 8.7 | 2.4 | 11.6 | 7.1 | 0.8 | 3.0 | 1.23 |
| Mike Venafro* | Col | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.8 | 4.5 | 11.3 | 6.8 | 0.0 | 1.5 | 1.25 |
| Jose Veras | NYA | mr | 25 | 0 | 0 | 2 | 0 | 5 | 0 | 0 | 0 | 6.5 | 4.1 | 10.6 | 3.4 | 0.7 | 0.8 | 1.18 |
| Justin Verlander | Det | sp | 23 | 7 | 3 | 3 | 4 | 2 | 3 | 3 | 5 | 9.8 | 3.1 | 13.2 | 5.8 | 1.3 | 1.8 | 1.44 |
| Carlos Villanueva | Mil | sp | 22 | 4 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 8.8 | 1.7 | 10.9 | 7.1 | 2.4 | 4.3 | 1.16 |
| Oscar Villarreal | Atl | mr | 24 | 5 | 5 | 2 | 6 | 2 | 0 | 7 | 6 | 9.2 | 2.0 | 11.6 | 5.1 | 1.8 | 2.6 | 1.24 |
| Ron Villone* | NYA | mr | 36 | 2 | 2 | 11 | 2 | 5 | 0 | 3 | 1 | 7.0 | 4.8 | 12.1 | 9.2 | 1.0 | 1.9 | 1.32 |
| Luis Vizcaino | Ari | mr | 31 | 7 | 3 | 0 | 5 | 0 | 0 | 3 | 5 | 6.9 | 3.8 | 11.2 | 9.2 | 1.6 | 2.4 | 1.19 |
| Ryan Vogelsong | Pit | mr | 28 | 7 | 2 | 8 | 7 | 9 | 1 | 4 | 3 | 11.5 | 5.3 | 17.9 | 6.2 | 0.5 | 1.2 | 1.86 |
| Edinson Volquez | Tex | sp | 22 | 3 | 1 | 0 | 2 | 1 | 0 | 2 | 1 | 12.5 | 2.5 | 15.5 | 3.8 | 1.3 | 1.5 | 1.67 |
| Doug Waechter | Tam | sp | 25 | 8 | 1 | 0 | 3 | 0 | 0 | 1 | 3 | 11.1 | 2.3 | 13.9 | 3.6 | 0.3 | 1.5 | 1.49 |
| Billy Wagner* | NYN | cl | 34 | 6 | 0 | 8 | 2 | 2 | 0 | 4 | 0 | 8.3 | 3.0 | 11.5 | 13.2 | 0.8 | 4.4 | 1.26 |
| Ryan Wagner | Was | mr | 23 | 5 | 0 | 3 | 2 | 3 | 1 | 1 | 1 | 13.9 | 5.8 | 20.3 | 5.0 | 1.9 | 0.9 | 2.20 |
| Adam Wainwright | StL | mr | 24 | 13 | 5 | 8 | 6 | 4 | 0 | 7 | 2 | 7.9 | 3.5 | 12.0 | 8.2 | 0.5 | 2.4 | 1.26 |
| Tim Wakefield | Bos | sp | 39 | 17 | 4 | 0 | 14 | 7 | 0 | 0 | 4 | 9.5 | 4.0 | 14.5 | 5.9 | 1.1 | 1.5 | 1.50 |
| Jamie Walker* | Det | mr | 34 | 1 | 1 | 4 | 2 | 0 | 0 | 0 | 4 | 6.7 | 2.0 | 9.0 | 5.2 | 1.1 | 2.6 | 0.97 |
| Pete Walker | Tor | mr | 37 | 2 | 0 | 5 | 3 | 1 | 0 | 1 | 2 | 12.3 | 3.7 | 16.6 | 7.8 | 1.7 | 2.1 | 1.78 |
| Tyler Walker |   | mr | 30 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 6.0 | 2.8 | 8.8 | 8.2 | 0.3 | 2.9 | 0.98 |
| Les Walrond* | ChN | mr | 29 | 0 | 2 | 2 | 1 | 1 | 0 | 3 | 2 | 12.2 | 4.4 | 17.0 | 12.2 | 2.6 | 2.8 | 1.84 |
| Chien-Ming Wang | NYA | sp | 26 | 6 | 2 | 9 | 4 | 11 | 2 | 4 | 5 | 9.2 | 2.1 | 11.5 | 2.6 | 0.3 | 1.2 | 1.26 |
| John Wasdin | Tex | sp | 33 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 7.0 | 2.4 | 9.7 | 3.5 | 0.3 | 1.4 | 1.05 |
| Jarrod Washburn* | Sea | sp | 31 | 5 | 6 | 6 | 7 | 2 | 0 | 6 | 6 | 8.8 | 2.7 | 11.9 | 5.0 | 1.4 | 1.8 | 1.28 |
| David Weathers | Cin | mr | 36 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 3 | 7.4 | 2.5 | 10.0 | 5.4 | 1.5 | 2.2 | 1.10 |
| Jeff Weaver |   | sp | 29 | 10 | 6 | 8 | 8 | 2 | 0 | 7 | 7 | 11.0 | 2.7 | 14.2 | 5.8 | 1.8 | 2.1 | 1.53 |
| Jered Weaver | LAA | sp | 23 | 17 | 2 | 7 | 1 | 1 | 0 | 1 | 4 | 7.1 | 3.0 | 10.1 | 7.7 | 1.3 | 2.6 | 1.12 |
| Brandon Webb | Ari | sp | 27 | 27 | 7 | 3 | 9 | 6 | 3 | 5 | 2 | 8.9 | 1.9 | 11.1 | 6.2 | 0.5 | 3.3 | 1.19 |
| Todd Wellemeyer |   | mr | 27 | 3 | 3 | 2 | 7 | 13 | 0 | 3 | 4 | 7.4 | 6.5 | 14.5 | 5.3 | 0.7 | 0.8 | 1.54 |
| David Wells* |   | sp | 43 | 2 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 9.4 | 1.4 | 11.3 | 5.1 | 0.6 | 3.8 | 1.19 |
| Kip Wells |   | sp | 29 | 1 | 3 | 4 | 6 | 2 | 0 | 1 | 1 | 13.9 | 5.0 | 20.6 | 3.9 | 1.4 | 0.8 | 2.10 |
| Jake Westbrook | Cle | sp | 28 | 15 | 8 | 1 | 5 | 7 | 0 | 7 | 3 | 10.4 | 2.6 | 13.2 | 4.4 | 0.5 | 1.7 | 1.44 |
| Dan Wheeler | Hou | mr | 28 | 2 | 0 | 6 | 3 | 0 | 0 | 1 | 3 | 8.1 | 3.3 | 11.8 | 8.8 | 1.0 | 2.6 | 1.27 |
| Rick White |   | mr | 37 | 5 | 0 | 7 | 4 | 6 | 2 | 2 | 1 | 11.5 | 3.6 | 15.5 | 5.7 | 2.0 | 1.6 | 1.67 |
| Bob Wickman |   | cl | 37 | 3 | 1 | 6 | 3 | 5 | 0 | 2 | 2 | 10.0 | 2.6 | 13.0 | 7.9 | 0.4 | 3.1 | 1.40 |
| Dave Williams* |   | sp | 27 | 2 | 0 | 2 | 3 | 1 | 0 | 1 | 1 | 9.4 | 3.1 | 12.9 | 3.8 | 1.3 | 1.2 | 1.39 |
| Jerome Williams | ChN | mr | 24 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 16.4 | 7.7 | 25.1 | 3.9 | 0.0 | 0.5 | 2.68 |
| Todd Williams | Bal | mr | 35 | 4 | 5 | 4 | 1 | 7 | 1 | 3 | 2 | 13.1 | 2.5 | 15.7 | 3.5 | 1.5 | 1.4 | 1.73 |
| Woody Williams | SD | sp | 39 | 13 | 5 | 2 | 5 | 1 | 0 | 4 | 13 | 10.1 | 1.9 | 12.2 | 4.1 | 1.0 | 2.2 | 1.32 |
| Scott Williamson |   | mr | 30 | 8 | 0 | 0 | 2 | 9 | 3 | 3 | 4 | 10.1 | 6.1 | 16.5 | 9.4 | 0.9 | 1.5 | 1.80 |
| Dontrelle Willis* | Flo | sp | 24 | 6 | 2 | 14 | 23 | 4 | 0 | 15 | 8 | 9.2 | 3.7 | 13.9 | 6.7 | 1.0 | 1.8 | 1.44 |
| Brian Wilson | SF | mr | 24 | 0 | 0 | 1 | 0 | 2 | 0 | 2 | 3 | 11.1 | 5.4 | 16.5 | 7.1 | 1.0 | 1.3 | 1.84 |
| C.J. Wilson* | Tex | mr | 25 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 9.4 | 4.1 | 14.1 | 8.3 | 1.7 | 2.0 | 1.50 |
| Kris Wilson | NYA | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 37.8 | 0.0 | 37.8 | 0.0 | 10.8 | 0.0 | 4.20 |
| Jason Windsor | Oak | sp | 23 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 19.1 | 9.0 | 28.1 | 4.5 | 1.1 | 0.5 | 3.13 |
| Joe Winkelsas | Mil | mr | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 13.9 | 7.3 | 21.2 | 3.6 | 2.2 | 0.5 | 2.35 |
| Matt Wise | Mil | mr | 30 | 2 | 0 | 1 | 6 | 2 | 2 | 1 | 0 | 9.2 | 1.6 | 11.8 | 5.3 | 1.2 | 3.3 | 1.20 |
| Jay Witasick | Oak | mr | 33 | 2 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 15.4 | 12.2 | 27.5 | 9.5 | 2.6 | 0.8 | 3.06 |
| Randy Wolf* | Phi | sp | 29 | 9 | 1 | 1 | 1 | 2 | 0 | 1 | 4 | 12.2 | 5.6 | 18.0 | 6.9 | 1.5 | 1.2 | 1.98 |
| Kerry Wood | ChN | sp | 29 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 11.5 | 3.0 | 15.0 | 8.0 | 4.0 | 2.7 | 1.61 |
| Mike Wood | KC | mr | 26 | 0 | 2 | 2 | 11 | 8 | 0 | 0 | 3 | 12.4 | 2.6 | 16.1 | 4.0 | 1.4 | 1.5 | 1.67 |
| Jake Woods* | Sea | mr | 24 | 4 | 4 | 12 | 4 | 4 | 0 | 4 | 6 | 8.1 | 4.2 | 12.6 | 6.1 | 0.5 | 1.5 | 1.37 |
| Tim Worrell | SF | cl | 38 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 2 | 8.2 | 3.9 | 12.5 | 4.7 | 0.8 | 1.2 | 1.35 |
| Jamey Wright | SF | sp | 31 | 6 | 5 | 2 | 5 | 4 | 0 | 6 | 3 | 9.7 | 3.4 | 13.3 | 4.6 | 1.0 | 1.4 | 1.45 |
| Jaret Wright | NYA | sp | 30 | 3 | 5 | 9 | 3 | 4 | 0 | 0 | 3 | 10.3 | 4.1 | 14.6 | 4.9 | 0.8 | 1.2 | 1.60 |
| Michael Wuertz | ChN | mr | 27 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 4.7 | 2.3 | 7.8 | 10.6 | 0.8 | 4.5 | 0.78 |
| Esteban Yan |   | mr | 31 | 1 | 0 | 5 | 2 | 11 | 0 | 3 | 2 | 8.0 | 5.6 | 14.0 | 5.8 | 1.7 | 1.0 | 1.51 |
| Tyler Yates | Atl | mr | 28 | 5 | 2 | 2 | 1 | 1 | 0 | 3 | 2 | 7.6 | 5.4 | 13.2 | 11.5 | 1.3 | 2.1 | 1.45 |
| Shane Youman* | Pit | sp | 26 | 1 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.5 | 4.5 | 10.0 | 2.0 | 1.0 | 0.4 | 1.11 |
| Chris Young | SD | sp | 27 | 21 | 7 | 3 | 3 | 2 | 0 | 7 | 2 | 6.6 | 3.5 | 10.2 | 8.7 | 1.2 | 2.5 | 1.12 |
| Carlos Zambrano | ChN | sp | 25 | 5 | 2 | 10 | 6 | 6 | 1 | 7 | 9 | 6.9 | 4.5 | 11.6 | 9.3 | 1.1 | 2.1 | 1.26 |
| Victor Zambrano | NYN | sp | 30 | 0 | 2 | 2 | 1 | 0 | 0 | 1 | 2 | 7.7 | 7.3 | 15.4 | 7.7 | 0.4 | 1.1 | 1.67 |
| Barry Zito* | Oak | sp | 28 | 7 | 1 | 6 | 8 | 1 | 1 | 4 | 5 | 8.0 | 3.4 | 11.8 | 6.4 | 1.0 | 1.9 | 1.27 |
| Joel Zumaya | Det | mr | 21 | 2 | 1 | 1 | 2 | 3 | 0 | 1 | 5 | 8.8 | 3.1 | 12.1 | 10.6 | 1.4 | 3.4 | 1.32 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| David Aardsma | ChN | mr | 24 | .895 | 119 | .269 | 108 | .565 | 110 | .576 | 32.9 | 7.1 | 6.30 | 6.17 |
| Winston Abreu | Bal | mr | 29 | 1.117 | 57 | .333 | 56 | .675 | 59 | .711 | 21.8 | 12.5 | 11.26 | 10.53 |
| Jeremy Accardo |   | mr | 24 | .562 | 151 | .265 | 76 | .335 | 78 | .344 | 17.3 | 2.8 | 2.55 | 2.32 |
| Jon Adkins | SD | mr | 28 | .674 | 250 | .276 | 129 | .394 | 133 | .407 | 32.1 | 3.6 | 3.30 | 3.25 |
| Jeremy Affeldt* |   | mr | 27 | .791 | 372 | .269 | 247 | .491 | 250 | .497 | 65.0 | 5.0 | 4.54 | 4.71 |
| Matt Albers | Hou | sp | 23 | .603 | 31 | .194 | 20 | .408 | 20 | .408 | 4.1 | 3.1 | 2.79 | 2.36 |
| Antonio Alfonseca | Tex | mr | 34 | .739 | 31 | .290 | 18 | .450 | 18 | .450 | 5.1 | 5.3 | 4.75 | 4.79 |
| Steve Andrade | KC | mr | 28 | .650 | 4 | .250 | 2 | .400 | 2 | .400 | 0.7 | 6.4 | 5.77 | 5.48 |
| Greg Aquino | Ari | mr | 28 | .831 | 241 | .328 | 198 | .514 | 199 | .517 | 56.8 | 5.9 | 5.33 | 5.33 |
| Tony Armas | Was | sp | 28 | .827 | 460 | .317 | 321 | .483 | 340 | .511 | 98.6 | 6.0 | 5.36 | 5.48 |
| Bronson Arroyo | Cin | sp | 29 | .651 | 694 | .241 | 402 | .404 | 409 | .411 | 92.6 | 3.4 | 3.09 | 3.02 |
| Miguel Asencio | Col | mr | 25 | 1.234 | 19 | .421 | 19 | .760 | 19 | .760 | 8.3 | 18.8 | 16.89 | 16.68 |
| Ezequiel Astacio | Hou | mr | 26 | 1.121 | 9 | .444 | 10 | .714 | 10 | .714 | 4.0 | 13.4 | 13.78 | 13.64 |
| Pedro Astacio | Was | sp | 36 | .915 | 329 | .316 | 232 | .560 | 233 | .563 | 76.0 | 7.6 | 6.86 | 6.34 |
| Brandon Backe | Hou | sp | 28 | .838 | 139 | .331 | 87 | .470 | 93 | .503 | 29.8 | 7.1 | 6.41 | 6.17 |
| Cha Seung Baek | Sea | sp | 26 | .864 | 94 | .266 | 73 | .533 | 77 | .562 | 20.9 | 6.1 | 5.65 | 6.07 |
| Danys Baez |   | mr | 28 | .718 | 225 | .284 | 130 | .428 | 135 | .444 | 37.5 | 4.8 | 4.30 | 3.77 |
| Jeff Bajenaru | Ari | mr | 28 | .468 | 9 | .111 | 5 | .357 | 5 | .357 | 0.9 | 2.7 | 2.47 | 3.04 |
| Scott Baker | Min | sp | 24 | .865 | 256 | .332 | 186 | .536 | 188 | .542 | 61.0 | 7.2 | 6.62 | 5.90 |
| Brian Bannister | NYN | sp | 25 | .734 | 86 | .233 | 59 | .465 | 60 | .472 | 17.5 | 5.6 | 5.07 | 4.76 |
| Kevin Barry | Atl | mr | 27 | .860 | 76 | .355 | 49 | .485 | 51 | .505 | 17.7 | 7.9 | 7.19 | 7.22 |
| Miguel Batista | Ari | sp | 35 | .877 | 555 | .335 | 385 | .527 | 390 | .534 | 122.1 | 6.9 | 6.26 | 6.40 |
| Rick Bauer | Tex | mr | 29 | .643 | 313 | .256 | 150 | .381 | 155 | .393 | 36.3 | 3.4 | 3.08 | 2.99 |
| Denny Bautista |   | mr | 23 | .929 | 132 | .326 | 98 | .560 | 102 | .583 | 33.3 | 8.0 | 7.23 | 6.61 |
| Jonah Bayliss | Pit | mr | 25 | .650 | 76 | .342 | 50 | .376 | 53 | .398 | 13.4 | 4.2 | 3.65 | 4.28 |
| T.J. Beam | NYA | mr | 25 | 1.235 | 38 | .368 | 48 | .774 | 51 | .823 | 18.9 | 14.2 | 12.40 | 11.91 |
| Josh Beckett | Bos | sp | 26 | .759 | 566 | .263 | 390 | .476 | 405 | .495 | 99.8 | 4.6 | 4.09 | 3.97 |
| Erik Bedard* | Bal | sp | 27 | .735 | 561 | .328 | 367 | .441 | 373 | .448 | 100.4 | 4.7 | 4.31 | 4.60 |
| Joe Beimel* | LAN | mr | 29 | .940 | 261 | .299 | 206 | .582 | 210 | .593 | 62.3 | 7.3 | 6.61 | 6.96 |
| Matt Belisle | Cin | mr | 26 | .711 | 204 | .270 | 113 | .422 | 115 | .429 | 28.5 | 4.1 | 3.73 | 4.27 |
| Heath Bell | NYN | mr | 28 | 1.091 | 106 | .425 | 95 | .655 | 95 | .655 | 36.3 | 11.3 | 10.02 | 10.68 |
| Armando Benitez | SF | cl | 33 | .837 | 199 | .347 | 146 | .509 | 146 | .509 | 47.0 | 6.9 | 6.21 | 6.43 |
| Joaquin Benoit | Tex | mr | 28 | .701 | 249 | .293 | 170 | .430 | 174 | .441 | 45.4 | 4.5 | 4.07 | 3.97 |
| Kris Benson | Bal | sp | 31 | .773 | 572 | .253 | 362 | .481 | 368 | .489 | 101.0 | 5.2 | 4.80 | 4.50 |
| Jason Bergmann | Was | mr | 24 | .834 | 243 | .284 | 180 | .504 | 190 | .532 | 53.4 | 5.9 | 5.50 | 4.96 |
| Adam Bernero |   | sp | 29 | .779 | 43 | .302 | 31 | .484 | 32 | .500 | 9.2 | 5.7 | 5.10 | 4.70 |
| Rafael Betancourt | Cle | mr | 31 | .546 | 257 | .241 | 111 | .327 | 112 | .330 | 24.5 | 2.5 | 2.28 | 1.72 |
| Chad Billingsley | LAN | sp | 21 | .724 | 274 | .270 | 181 | .448 | 182 | .450 | 47.5 | 4.7 | 4.23 | 4.68 |
| Kurt Birkins* | Bal | mr | 25 | .467 | 109 | .193 | 48 | .284 | 51 | .302 | 8.9 | 1.9 | 1.72 | 1.82 |
| Joe Blanton | Oak | sp | 25 | .682 | 631 | .301 | 325 | .396 | 332 | .404 | 85.2 | 3.9 | 3.59 | 3.58 |
| Jeremy Bonderman | Det | sp | 23 | .700 | 631 | .312 | 380 | .424 | 386 | .430 | 98.9 | 4.1 | 3.76 | 3.49 |
| Boof Bonser | Min | sp | 24 | .900 | 287 | .331 | 232 | .567 | 234 | .572 | 64.4 | 6.0 | 5.42 | 6.04 |
| Chris Booker |   | mr | 29 | .602 | 56 | .196 | 27 | .386 | 27 | .386 | 6.1 | 3.0 | 2.73 | 2.19 |
| Chris Bootcheck | LAA | mr | 27 | 1.073 | 49 | .347 | 59 | .694 | 59 | .694 | 20.5 | 11.3 | 10.17 | 10.28 |
| Dave Borkowski | Hou | mr | 29 | .750 | 331 | .302 | 214 | .469 | 214 | .469 | 57.1 | 4.8 | 4.28 | 3.84 |
| Joe Borowski | Flo | cl | 35 | .687 | 269 | .320 | 156 | .411 | 158 | .416 | 43.6 | 4.5 | 4.19 | 3.94 |
| Micah Bowie* | Was | mr | 31 | .602 | 55 | .236 | 26 | .377 | 26 | .377 | 6.3 | 3.6 | 3.27 | 3.02 |
| Chad Bradford | NYN | mr | 31 | .594 | 196 | .306 | 89 | .338 | 89 | .338 | 18.6 | 2.5 | 2.22 | 2.10 |
| Ryan Braun | KC | mr | 25 | .950 | 25 | .400 | 20 | .556 | 20 | .556 | 7.0 | 8.6 | 7.77 | 8.12 |
| Bill Bray* |   | mr | 23 | .808 | 181 | .343 | 127 | .492 | 128 | .496 | 35.9 | 5.6 | 5.13 | 5.32 |
| Dewon Brazelton | SD | mr | 26 | 1.043 | 53 | .302 | 48 | .649 | 48 | .649 | 16.8 | 9.9 | 8.87 | 9.37 |
| Craig Breslow* | Bos | mr | 25 | .668 | 23 | .261 | 13 | .371 | 15 | .429 | 3.5 | 4.2 | 3.92 | 4.28 |
| Eude Brito* | Phi | mr | 27 | 1.276 | 20 | .500 | 25 | .758 | 26 | .788 | 12.2 | 22.0 | 19.78 | 16.65 |
| Chris Britton | Bal | mr | 23 | .689 | 158 | .297 | 89 | .414 | 89 | .414 | 23.0 | 4.0 | 3.58 | 3.35 |
| Doug Brocail | SD | mr | 39 | .663 | 49 | .306 | 24 | .369 | 25 | .385 | 6.6 | 4.2 | 3.75 | 4.16 |
| Jim Brower |   | mr | 33 | 1.145 | 67 | .418 | 58 | .644 | 61 | .678 | 24.8 | 14.6 | 13.10 | 13.65 |
| Andrew Brown | Cle | mr | 25 | .728 | 62 | .258 | 39 | .448 | 40 | .460 | 10.1 | 4.5 | 3.94 | 4.12 |
| Jonathan Broxton | LAN | mr | 22 | .752 | 194 | .309 | 172 | .485 | 175 | .493 | 44.5 | 4.7 | 4.26 | 3.84 |
| Brian Bruney | NYA | mr | 24 | .877 | 21 | .429 | 24 | .533 | 24 | .533 | 7.0 | 7.3 | 6.58 | 7.57 |
| Taylor Buchholz | Hou | sp | 24 | .892 | 323 | .276 | 247 | .569 | 250 | .576 | 71.8 | 6.5 | 5.84 | 5.57 |
| Mark Buehrle* | ChA | sp | 27 | .906 | 612 | .328 | 438 | .550 | 449 | .563 | 140.6 | 7.3 | 6.53 | 6.44 |
| Ambiorix Burgos | KC | cl | 22 | .923 | 281 | .327 | 260 | .564 | 269 | .584 | 79.1 | 7.1 | 6.29 | 7.10 |
| A.J. Burnett | Tor | sp | 29 | .882 | 361 | .363 | 267 | .528 | 273 | .540 | 84.8 | 6.8 | 6.23 | 6.24 |
| Mike Burns |   | mr | 27 | 1.303 | 78 | .538 | 78 | .772 | 79 | .782 | 37.6 | 21.1 | 18.63 | 18.40 |
| Brian Burres* | Bal | mr | 25 | .580 | 12 | .250 | 4 | .286 | 4 | .286 | 1.2 | 3.1 | 2.80 | 2.02 |
| Dave Bush | Mil | sp | 26 | .732 | 611 | .264 | 398 | .447 | 418 | .470 | 102.2 | 4.2 | 3.85 | 3.62 |
| Paul Byrd | Cle | sp | 35 | .754 | 681 | .280 | 375 | .453 | 381 | .461 | 105.2 | 4.9 | 4.48 | 4.30 |
| Tim Byrdak* | Bal | mr | 32 | 1.370 | 39 | .462 | 52 | .813 | 54 | .844 | 20.7 | 17.5 | 17.96 | 20.66 |
| Daniel Cabrera | Bal | sp | 25 | .718 | 374 | .286 | 284 | .459 | 287 | .464 | 68.6 | 4.3 | 3.92 | 4.11 |
| Fernando Cabrera | Cle | mr | 24 | .928 | 165 | .321 | 178 | .605 | 179 | .609 | 52.2 | 7.2 | 6.34 | 6.27 |
| Matt Cain | SF | sp | 21 | .642 | 517 | .267 | 327 | .407 | 330 | .410 | 76.0 | 3.5 | 3.14 | 2.67 |
| Kiko Calero | Oak | mr | 31 | .793 | 185 | .368 | 151 | .484 | 151 | .484 | 39.6 | 4.9 | 4.43 | 4.72 |
| Shawn Camp | Tam | mr | 30 | 1.005 | 351 | .436 | 260 | .568 | 270 | .590 | 95.5 | 9.1 | 8.44 | 9.11 |
| Jose Capellan | Mil | mr | 25 | .745 | 225 | .258 | 161 | .485 | 161 | .485 | 41.9 | 4.8 | 4.33 | 3.83 |
| Matt Capps | Pit | mr | 22 | .603 | 331 | .275 | 154 | .346 | 160 | .360 | 33.0 | 2.6 | 2.32 | 2.24 |
| Chris Capuano* | Mil | sp | 27 | .771 | 692 | .308 | 447 | .470 | 456 | .479 | 123.4 | 4.9 | 4.49 | 4.12 |
| Fausto Carmona | Cle | mr | 22 | .849 | 237 | .354 | 156 | .489 | 161 | .505 | 49.9 | 6.4 | 5.89 | 5.99 |
| Chris Carpenter | StL | sp | 31 | .748 | 599 | .295 | 389 | .458 | 395 | .465 | 99.6 | 4.3 | 3.93 | 3.82 |
| Giovanni Carrara | LAN | mr | 38 | .971 | 79 | .241 | 78 | .650 | 78 | .650 | 23.9 | 8.0 | 7.17 | 6.44 |
| Hector Carrasco | LAA | mr | 36 | .688 | 381 | .278 | 218 | .417 | 222 | .424 | 53.3 | 3.8 | 3.38 | 3.43 |
| Lance Carter | LAN | mr | 31 | .762 | 13 | .308 | 7 | .467 | 7 | .467 | 2.1 | 5.6 | 5.07 | 3.97 |
| Santiago Casilla | Oak | mr | 26 | .500 | 2 | .500 | 1 | .250 | 1 | .250 | 0.3 | 2.3 | 2.03 | 1.95 |
| Scott Cassidy | SD | mr | 30 | .942 | 102 | .412 | 116 | .611 | 116 | .611 | 35.5 | 7.4 | 6.58 | 6.19 |
| Fabio Castro* |   | mr | 21 | .528 | 147 | .190 | 66 | .324 | 71 | .348 | 13.4 | 2.3 | 2.11 | 1.81 |
| Gustavo Chacin* | Tor | sp | 25 | .839 | 243 | .251 | 199 | .545 | 205 | .562 | 55.5 | 6.0 | 5.46 | 4.91 |
| Shawn Chacon |   | sp | 28 | .918 | 298 | .279 | 255 | .569 | 266 | .594 | 80.7 | 7.7 | 6.95 | 6.83 |
| Bruce Chen* | Bal | mr | 29 | .977 | 341 | .317 | 308 | .625 | 311 | .631 | 101.3 | 8.5 | 7.69 | 7.75 |
| Jason Childers | Tam | mr | 31 | 1.034 | 29 | .414 | 25 | .625 | 25 | .625 | 8.4 | 9.5 | 8.91 | 10.77 |
| Randy Choate* | Ari | mr | 30 | .850 | 84 | .381 | 44 | .415 | 51 | .481 | 15.6 | 6.1 | 5.65 | 6.78 |
| Vinnie Chulk |   | mr | 27 | .760 | 130 | .269 | 102 | .479 | 105 | .493 | 26.8 | 4.9 | 4.41 | 4.72 |
| Brandon Claussen* | Cin | sp | 27 | 1.028 | 190 | .384 | 185 | .613 | 189 | .626 | 68.4 | 10.5 | 9.24 | 9.02 |
| Roger Clemens | Hou | sp | 43 | .556 | 321 | .221 | 169 | .353 | 172 | .359 | 33.1 | 2.4 | 2.17 | 1.91 |
| Matt Clement | Bos | sp | 31 | .759 | 205 | .288 | 139 | .465 | 143 | .478 | 37.1 | 4.9 | 4.44 | 4.83 |
| Todd Coffey | Cin | mr | 25 | .812 | 324 | .315 | 216 | .490 | 222 | .503 | 59.0 | 5.2 | 4.66 | 4.77 |
| Bartolo Colon | LAA | sp | 33 | .826 | 185 | .292 | 128 | .518 | 131 | .530 | 36.2 | 5.6 | 5.03 | 4.43 |
| Roman Colon | Det | mr | 26 | .696 | 133 | .263 | 81 | .435 | 81 | .435 | 19.9 | 4.0 | 3.82 | 3.69 |
| Clay Condrey | Phi | mr | 30 | .869 | 106 | .330 | 70 | .519 | 71 | .526 | 20.4 | 5.9 | 5.50 | 5.80 |
| Jose Contreras | ChA | sp | 34 | .721 | 555 | .294 | 323 | .425 | 338 | .445 | 91.2 | 4.6 | 4.22 | 4.05 |
| Aaron Cook | Col | sp | 27 | .794 | 645 | .315 | 369 | .473 | 371 | .476 | 101.0 | 5.0 | 4.50 | 4.55 |
| Roy Corcoran | Was | mr | 26 | .950 | 25 | .320 | 17 | .607 | 17 | .607 | 5.8 | 8.7 | 7.84 | 6.43 |
| Tim Corcoran | Tam | sp | 28 | .789 | 288 | .288 | 198 | .490 | 202 | .500 | 53.0 | 5.2 | 4.70 | 4.89 |
| Chad Cordero | Was | cl | 24 | .690 | 258 | .252 | 169 | .441 | 170 | .444 | 41.9 | 4.0 | 3.66 | 3.34 |
| Francisco Cordero |   | cl | 31 | .685 | 229 | .293 | 169 | .432 | 174 | .445 | 41.8 | 4.0 | 3.61 | 3.23 |
| Bryan Corey |   | mr | 32 | .757 | 47 | .383 | 27 | .435 | 27 | .435 | 8.3 | 5.6 | 5.02 | 5.18 |
| Lance Cormier | Atl | mr | 25 | .899 | 252 | .329 | 182 | .540 | 184 | .546 | 56.8 | 7.0 | 6.42 | 6.50 |
| Rheal Cormier* |   | mr | 39 | .731 | 222 | .221 | 123 | .452 | 127 | .467 | 31.3 | 4.4 | 4.05 | 4.04 |
| Manuel Corpas | Col | mr | 23 | .878 | 92 | .424 | 62 | .500 | 64 | .516 | 21.6 | 7.3 | 6.65 | 6.05 |
| Kevin Correia | SF | mr | 25 | .681 | 273 | .267 | 171 | .429 | 173 | .434 | 43.7 | 4.2 | 3.82 | 3.15 |
| David Cortes | Col | mr | 32 | .761 | 155 | .355 | 80 | .412 | 82 | .423 | 24.9 | 5.1 | 4.52 | 4.93 |
| Neal Cotts* | ChA | mr | 26 | .742 | 248 | .230 | 181 | .483 | 184 | .491 | 44.0 | 4.5 | 4.09 | 3.92 |
| Jesse Crain | Min | mr | 24 | .572 | 200 | .240 | 95 | .343 | 98 | .354 | 20.7 | 2.7 | 2.42 | 2.13 |
| Francisco Cruceta | Sea | mr | 24 | 1.059 | 16 | .375 | 15 | .652 | 15 | .652 | 5.2 | 9.4 | 8.50 | 7.46 |
| Juan Cruz | Ari | mr | 27 | .632 | 325 | .265 | 185 | .370 | 198 | .396 | 44.9 | 3.4 | 3.13 | 3.24 |
| Casey Daigle | Ari | mr | 25 | .591 | 23 | .304 | 9 | .321 | 9 | .321 | 1.9 | 2.4 | 2.18 | 3.13 |
| Kyle Davies | Atl | sp | 22 | .948 | 166 | .349 | 144 | .574 | 147 | .586 | 48.6 | 8.5 | 7.67 | 7.86 |
| Doug Davis* | Mil | sp | 30 | .770 | 609 | .304 | 428 | .473 | 433 | .478 | 120.9 | 5.4 | 4.85 | 4.81 |
| Jason Davis | Cle | mr | 26 | .701 | 233 | .326 | 124 | .415 | 125 | .418 | 32.7 | 4.1 | 3.77 | 3.55 |
| Zach Day |   | sp | 28 | .814 | 145 | .359 | 79 | .457 | 81 | .468 | 25.9 | 6.1 | 5.24 | 5.73 |
| Jorge De La Rosa* |   | mr | 25 | .955 | 191 | .361 | 178 | .584 | 179 | .587 | 60.5 | 9.1 | 8.12 | 9.02 |
| Manny Delcarmen | Bos | mr | 24 | .756 | 170 | .329 | 105 | .453 | 106 | .457 | 29.5 | 5.0 | 4.59 | 4.46 |
| Chris Demaria | Mil | mr | 25 | .985 | 28 | .286 | 33 | .660 | 33 | .660 | 10.0 | 8.5 | 7.61 | 7.77 |
| Ryan Dempster | ChN | cl | 29 | .672 | 232 | .289 | 132 | .400 | 135 | .409 | 33.3 | 3.8 | 3.40 | 3.40 |
| Elmer Dessens |   | mr | 35 | .619 | 200 | .255 | 96 | .368 | 99 | .379 | 20.9 | 2.8 | 2.61 | 2.73 |
| Joey Devine | Atl | mr | 22 | .657 | 21 | .286 | 16 | .381 | 18 | .429 | 4.6 | 4.8 | 4.33 | 4.31 |
| R.A. Dickey | Tex | sp | 31 | .761 | 20 | .100 | 15 | .556 | 15 | .556 | 2.6 | 3.2 | 3.06 | 3.29 |
| Lenny DiNardo* | Bos | mr | 26 | .865 | 145 | .303 | 101 | .540 | 102 | .545 | 29.4 | 6.4 | 5.95 | 6.21 |
| Scott Dohmann |   | mr | 28 | .882 | 123 | .325 | 107 | .538 | 110 | .553 | 33.2 | 7.2 | 6.56 | 7.13 |
| Brendan Donnelly | LAA | mr | 34 | .575 | 201 | .189 | 109 | .366 | 113 | .379 | 21.2 | 2.5 | 2.30 | 2.33 |
| Octavio Dotel | NYA | mr | 32 | 1.401 | 15 | .533 | 17 | .773 | 18 | .818 | 9.1 | 30.7 | 27.64 | 32.29 |
| Scott Downs* | Tor | mr | 30 | .655 | 278 | .259 | 169 | .410 | 172 | .417 | 38.3 | 3.4 | 3.05 | 2.93 |
| Ryan Drese | Was | sp | 30 | .948 | 20 | .400 | 17 | .531 | 17 | .531 | 5.6 | 8.9 | 7.97 | 11.23 |
| Justin Duchscherer | Oak | mr | 28 | .529 | 164 | .268 | 76 | .313 | 77 | .317 | 16.5 | 2.4 | 2.20 | 1.98 |
| Brandon Duckworth | KC | sp | 30 | .916 | 140 | .357 | 99 | .550 | 101 | .561 | 31.6 | 7.2 | 6.45 | 6.53 |
| Zach Duke* | Pit | sp | 23 | .757 | 650 | .305 | 382 | .451 | 386 | .456 | 103.5 | 4.8 | 4.30 | 4.58 |
| Scott Dunn | Tam | mr | 28 | .752 | 47 | .340 | 21 | .396 | 22 | .415 | 7.4 | 6.0 | 5.61 | 5.84 |
| Chad Durbin | Det | mr | 28 | .545 | 23 | .261 | 9 | .310 | 9 | .310 | 1.9 | 2.4 | 2.14 | 2.09 |
| Adam Eaton | Tex | sp | 28 | .914 | 217 | .364 | 166 | .551 | 169 | .561 | 53.2 | 7.3 | 6.63 | 6.86 |
| Joey Eischen* | Was | mr | 36 | .771 | 48 | .354 | 40 | .476 | 40 | .476 | 10.6 | 5.4 | 4.78 | 5.26 |
| Scott Elarton | KC | sp | 30 | .829 | 340 | .262 | 235 | .506 | 244 | .526 | 67.9 | 5.8 | 5.38 | 5.37 |
| Alan Embree* | SD | mr | 36 | .667 | 162 | .358 | 103 | .387 | 105 | .395 | 24.7 | 3.5 | 3.09 | 3.55 |
| Scott Erickson | NYA | mr | 38 | .750 | 3 | .333 | 2 | .500 | 2 | .500 | 0.5 | 4.5 | 4.05 | 1.95 |
| Kelvim Escobar | LAA | sp | 30 | .668 | 582 | .290 | 312 | .396 | 318 | .404 | 79.0 | 3.7 | 3.40 | 3.29 |
| Shawn Estes* | SD | sp | 33 | .500 | 29 | .276 | 8 | .250 | 8 | .250 | 1.5 | 1.6 | 1.35 | 1.68 |
| Seth Etherton | KC | sp | 29 | 1.137 | 31 | .387 | 30 | .714 | 30 | .714 | 12.2 | 14.4 | 12.92 | 13.42 |
| Dana Eveland* | Mil | sp | 22 | .704 | 69 | .290 | 54 | .450 | 54 | .450 | 14.1 | 4.4 | 3.89 | 3.53 |
| Scott Eyre* | ChN | mr | 34 | .835 | 170 | .324 | 158 | .527 | 159 | .530 | 44.0 | 5.7 | 5.10 | 5.14 |
| Willie Eyre | Min | mr | 27 | .860 | 275 | .305 | 177 | .510 | 184 | .530 | 56.5 | 6.8 | 6.10 | 5.94 |
| Brian Falkenborg | StL | mr | 28 | .688 | 24 | .292 | 12 | .387 | 13 | .419 | 3.4 | 4.4 | 3.94 | 4.03 |
| Kyle Farnsworth | NYA | mr | 30 | .771 | 258 | .314 | 189 | .481 | 190 | .483 | 52.1 | 5.3 | 4.74 | 4.81 |
| Jeff Fassero* | SF | mr | 43 | 1.115 | 41 | .366 | 47 | .712 | 47 | .712 | 14.9 | 9.8 | 8.83 | 11.29 |
| Ryan Feierabend* | Sea | sp | 20 | .552 | 35 | .200 | 19 | .365 | 19 | .365 | 2.8 | 1.8 | 1.59 | 1.89 |
| Scott Feldman | Tex | mr | 23 | .757 | 180 | .317 | 105 | .434 | 111 | .459 | 31.5 | 5.2 | 4.70 | 4.91 |
| Pedro Feliciano* | NYN | mr | 29 | .747 | 231 | .307 | 148 | .442 | 153 | .457 | 41.3 | 5.0 | 4.63 | 5.06 |
| Nate Field | Col | mr | 30 | 1.065 | 18 | .333 | 21 | .724 | 21 | .724 | 6.6 | 9.3 | 8.86 | 5.33 |
| Randy Flores* | StL | mr | 30 | .771 | 179 | .279 | 136 | .472 | 143 | .497 | 36.7 | 4.9 | 4.45 | 4.52 |
| Ron Flores* | Oak | mr | 26 | .700 | 97 | .268 | 61 | .452 | 61 | .452 | 14.0 | 3.8 | 3.43 | 2.88 |
| Gavin Floyd | Phi | sp | 23 | 1.073 | 140 | .314 | 133 | .646 | 138 | .670 | 47.8 | 10.4 | 9.37 | 9.22 |
| Josh Fogg | Col | sp | 29 | .913 | 609 | .327 | 430 | .562 | 431 | .563 | 135.0 | 7.2 | 6.67 | 6.25 |
| Casey Fossum* | Tam | sp | 28 | .814 | 413 | .293 | 279 | .483 | 296 | .512 | 84.2 | 5.9 | 5.34 | 5.35 |
| Keith Foulke | Bos | mr | 33 | .778 | 186 | .253 | 127 | .498 | 131 | .514 | 32.6 | 4.7 | 4.22 | 3.65 |
| Jeff Francis* | Col | sp | 25 | .704 | 612 | .288 | 336 | .416 | 349 | .432 | 89.1 | 4.2 | 3.76 | 3.37 |
| Frank Francisco | Tex | mr | 26 | 1.216 | 16 | .438 | 17 | .773 | 17 | .773 | 7.4 | 16.6 | 14.97 | 15.29 |
| Ryan Franklin |   | mr | 33 | .846 | 286 | .301 | 191 | .509 | 202 | .539 | 58.3 | 6.2 | 5.60 | 4.87 |
| Wayne Franklin* | Atl | mr | 32 | .503 | 10 | .100 | 6 | .353 | 7 | .412 | 1.1 | 2.8 | 2.33 | 3.96 |
| Jason Frasor | Tor | mr | 28 | .773 | 184 | .277 | 151 | .498 | 153 | .505 | 41.2 | 5.3 | 4.91 | 4.93 |
| Emiliano Fruto | Sea | mr | 22 | .842 | 128 | .336 | 112 | .526 | 113 | .531 | 34.3 | 6.9 | 6.18 | 6.31 |
| Brian Fuentes* | Col | cl | 30 | .687 | 207 | .251 | 154 | .430 | 160 | .447 | 38.2 | 4.1 | 3.74 | 3.68 |
| Aaron Fultz* | Phi | mr | 32 | .911 | 229 | .384 | 184 | .549 | 189 | .564 | 60.6 | 7.8 | 6.98 | 6.52 |
| Kason Gabbard* | Bos | sp | 24 | .504 | 83 | .217 | 37 | .319 | 37 | .319 | 6.6 | 2.1 | 1.90 | 2.31 |
| Mike Gallo* | Hou | mr | 28 | 1.111 | 49 | .490 | 43 | .597 | 46 | .639 | 18.0 | 12.8 | 11.23 | 14.29 |
| Freddy Garcia | ChA | sp | 30 | .702 | 672 | .254 | 378 | .431 | 385 | .439 | 95.3 | 4.0 | 3.64 | 3.42 |
| Jose Garcia | Flo | mr | 21 | .414 | 22 | .182 | 6 | .240 | 6 | .240 | 1.1 | 1.5 | 1.46 | 1.51 |
| Jon Garland | ChA | sp | 26 | .849 | 603 | .327 | 390 | .511 | 397 | .520 | 117.9 | 6.1 | 5.47 | 5.33 |
| Matt Garza | Min | sp | 22 | .834 | 145 | .310 | 105 | .515 | 106 | .520 | 30.9 | 6.1 | 5.61 | 5.84 |
| Chad Gaudin | Oak | mr | 23 | .779 | 179 | .274 | 121 | .478 | 124 | .490 | 32.1 | 5.1 | 4.70 | 5.20 |
| Geoff Geary | Phi | mr | 29 | .694 | 293 | .321 | 153 | .385 | 159 | .401 | 40.6 | 3.9 | 3.57 | 3.68 |
| Franklyn German | Flo | mr | 26 | .645 | 69 | .232 | 37 | .398 | 38 | .409 | 9.3 | 3.9 | 3.53 | 2.80 |
| Justin Germano | Cin | sp | 23 | .711 | 11 | .000 | 8 | .421 | 10 | .526 | 1.4 | 2.4 | 2.31 | 2.56 |
| Tom Glavine* | NYN | sp | 40 | .813 | 555 | .333 | 358 | .483 | 366 | .494 | 105.8 | 5.7 | 5.14 | 4.84 |
| Jimmy Gobble* | KC | mr | 24 | .764 | 238 | .294 | 176 | .473 | 180 | .484 | 47.9 | 5.0 | 4.55 | 4.50 |
| Edgar Gonzalez | Ari | mr | 23 | .802 | 186 | .280 | 123 | .502 | 127 | .518 | 35.7 | 5.6 | 5.16 | 4.26 |
| Enrique Gonzalez | Ari | sp | 23 | .637 | 365 | .263 | 185 | .384 | 187 | .388 | 45.4 | 3.5 | 3.16 | 2.96 |
| Geremi Gonzalez |   | mr | 31 | .835 | 218 | .349 | 161 | .511 | 163 | .517 | 50.6 | 6.6 | 5.97 | 5.30 |
| Mike Gonzalez* | Pit | cl | 28 | .596 | 183 | .290 | 114 | .362 | 118 | .375 | 27.4 | 3.4 | 3.04 | 3.15 |
| Tom Gordon | Phi | cl | 38 | .849 | 181 | .287 | 167 | .542 | 171 | .555 | 46.8 | 6.0 | 5.50 | 5.58 |
| Tom Gorzelanny* | Pit | sp | 23 | .670 | 200 | .260 | 114 | .401 | 117 | .412 | 29.7 | 4.0 | 3.69 | 3.40 |
| Mike Gosling* | Cin | mr | 25 | .500 | 4 | .250 | 1 | .250 | 1 | .250 | 0.3 | 2.3 | 2.03 | 1.95 |
| John Grabow* | Pit | mr | 27 | .765 | 216 | .292 | 166 | .488 | 168 | .494 | 42.7 | 4.8 | 4.31 | 3.87 |
| Danny Graves | Cle | mr | 32 | .853 | 30 | .267 | 18 | .529 | 18 | .529 | 4.8 | 5.4 | 5.07 | 5.31 |
| Sean Green | Sea | mr | 27 | .628 | 157 | .242 | 75 | .375 | 77 | .385 | 14.7 | 2.6 | 2.40 | 3.06 |
| Kevin Gregg | LAA | mr | 28 | .875 | 234 | .350 | 198 | .550 | 198 | .550 | 64.3 | 7.3 | 6.62 | 6.21 |
| Jason Grilli | Det | mr | 29 | .797 | 258 | .302 | 156 | .468 | 164 | .492 | 47.0 | 5.9 | 5.29 | 5.03 |
| Jason Grimsley | Ari | mr | 38 | .886 | 123 | .285 | 84 | .528 | 87 | .547 | 26.1 | 6.6 | 5.76 | 5.65 |
| Kevin Gryboski | Was | mr | 32 | 1.338 | 20 | .550 | 25 | .781 | 26 | .813 | 12.1 | 20.5 | 18.45 | 17.23 |
| Eddie Guardado* |   | cl | 35 | .912 | 93 | .333 | 94 | .584 | 95 | .590 | 28.1 | 7.2 | 6.63 | 6.25 |
| Matt Guerrier | Min | mr | 27 | .781 | 326 | .310 | 202 | .476 | 203 | .479 | 57.8 | 5.5 | 4.95 | 4.71 |
| Jeremy Guthrie | Cle | mr | 27 | .916 | 63 | .365 | 48 | .539 | 50 | .562 | 16.6 | 8.3 | 7.46 | 6.71 |
| Angel Guzman | ChN | sp | 24 | 1.035 | 134 | .373 | 144 | .658 | 146 | .667 | 52.8 | 11.0 | 9.80 | 9.02 |
| Charlie Haeger | ChA | mr | 22 | .889 | 41 | .415 | 32 | .516 | 32 | .516 | 11.5 | 9.1 | 8.20 | 8.46 |
| John Halama* | Bal | mr | 34 | .864 | 108 | .278 | 78 | .549 | 79 | .556 | 22.7 | 6.5 | 5.81 | 5.60 |
| Roy Halladay | Tor | sp | 29 | .660 | 700 | .251 | 370 | .407 | 376 | .414 | 90.8 | 3.7 | 3.29 | 3.01 |
| Brad Halsey* | Oak | mr | 25 | .699 | 275 | .291 | 157 | .419 | 160 | .427 | 40.9 | 4.2 | 3.76 | 3.97 |
| Cole Hamels* | Phi | sp | 22 | .701 | 346 | .280 | 258 | .449 | 260 | .452 | 62.8 | 4.1 | 3.73 | 3.22 |
| Jason Hammel | Tam | sp | 23 | .904 | 125 | .360 | 95 | .543 | 97 | .554 | 30.1 | 7.3 | 6.58 | 6.31 |
| Chris Hammond* | Cin | mr | 40 | .649 | 118 | .297 | 67 | .392 | 68 | .398 | 17.3 | 3.9 | 3.71 | 3.52 |
| Justin Hampson* | Col | mr | 26 | .509 | 21 | .190 | 9 | .333 | 9 | .333 | 1.9 | 2.6 | 2.30 | 1.61 |
| Tim Hamulack* | LAN | mr | 29 | .877 | 111 | .360 | 97 | .530 | 100 | .546 | 29.7 | 6.7 | 5.93 | 6.42 |
| Josh Hancock | StL | mr | 28 | .789 | 251 | .287 | 171 | .493 | 175 | .504 | 42.2 | 4.5 | 4.05 | 3.95 |
| Devern Hansack | Bos | sp | 28 | .595 | 26 | .154 | 17 | .415 | 17 | .415 | 2.7 | 2.2 | 2.02 | 2.20 |
| Craig Hansen | Bos | mr | 22 | .815 | 71 | .282 | 53 | .525 | 53 | .525 | 15.1 | 5.9 | 5.32 | 5.32 |
| Aaron Harang | Cin | sp | 28 | .737 | 594 | .306 | 396 | .449 | 404 | .459 | 109.2 | 4.7 | 4.36 | 3.99 |
| Rich Harden | Oak | sp | 24 | .511 | 133 | .233 | 71 | .326 | 72 | .330 | 12.7 | 2.1 | 1.87 | 2.07 |
| Dan Haren | Oak | sp | 25 | .730 | 611 | .272 | 388 | .454 | 399 | .467 | 101.6 | 4.4 | 4.02 | 3.59 |
| Travis Harper | Tam | mr | 30 | .855 | 148 | .345 | 106 | .520 | 108 | .529 | 30.3 | 5.8 | 5.11 | 5.22 |
| Chad Harville | Tam | mr | 29 | .719 | 119 | .277 | 83 | .461 | 83 | .461 | 19.9 | 4.1 | 3.64 | 3.68 |
| LaTroy Hawkins | Bal | mr | 33 | .659 | 283 | .272 | 137 | .389 | 138 | .392 | 33.3 | 3.6 | 3.29 | 3.45 |
| Aaron Heilman | NYN | mr | 27 | .751 | 314 | .306 | 201 | .456 | 203 | .460 | 55.5 | 4.8 | 4.35 | 3.73 |
| Rick Helling | Mil | mr | 35 | .559 | 68 | .235 | 39 | .364 | 40 | .374 | 7.9 | 2.6 | 2.40 | 1.63 |
| Ben Hendrickson | Mil | sp | 25 | .776 | 36 | .278 | 27 | .491 | 27 | .491 | 8.9 | 7.5 | 7.21 | 6.17 |
| Mark Hendrickson* |   | sp | 32 | .694 | 511 | .258 | 285 | .422 | 290 | .430 | 73.3 | 4.1 | 3.74 | 3.54 |
| Sean Henn* | NYA | mr | 25 | 1.041 | 16 | .313 | 15 | .652 | 15 | .652 | 5.5 | 10.6 | 8.93 | 6.67 |
| Brad Hennessey | SF | mr | 26 | .804 | 355 | .268 | 227 | .481 | 238 | .504 | 66.9 | 5.6 | 5.07 | 5.20 |
| Clay Hensley | SD | sp | 26 | .732 | 524 | .296 | 320 | .438 | 327 | .448 | 86.0 | 4.7 | 4.24 | 4.56 |
| Matt Herges | Flo | mr | 36 | .846 | 247 | .368 | 151 | .473 | 158 | .495 | 48.5 | 6.2 | 5.70 | 6.10 |
| Dustin Hermanson | ChA | mr | 33 | .419 | 11 | .000 | 5 | .333 | 5 | .333 | 0.6 | 1.2 | 1.06 | 0.86 |
| Felix Hernandez | Sea | sp | 20 | .749 | 582 | .311 | 394 | .461 | 400 | .468 | 105.7 | 4.7 | 4.20 | 4.10 |
| Livan Hernandez |   | sp | 31 | .775 | 617 | .319 | 381 | .462 | 384 | .466 | 114.1 | 5.5 | 5.01 | 4.61 |
| Orlando Hernandez |   | sp | 36 | .731 | 473 | .268 | 343 | .461 | 351 | .472 | 89.7 | 4.6 | 4.20 | 3.57 |
| Roberto Hernandez |   | mr | 41 | .688 | 262 | .282 | 149 | .417 | 150 | .420 | 38.0 | 4.0 | 3.66 | 3.50 |
| Runelvys Hernandez | KC | sp | 28 | .927 | 373 | .311 | 277 | .562 | 284 | .576 | 90.0 | 7.8 | 7.03 | 7.66 |
| Rich Hill* | ChN | sp | 26 | .640 | 282 | .248 | 172 | .401 | 175 | .408 | 41.8 | 3.6 | 3.29 | 2.97 |
| Shawn Hill | Was | sp | 25 | .760 | 124 | .290 | 71 | .447 | 74 | .465 | 20.4 | 5.2 | 4.72 | 4.54 |
| Jason Hirsh | Hou | sp | 24 | .797 | 130 | .223 | 96 | .516 | 97 | .522 | 25.4 | 5.2 | 4.82 | 4.58 |
| James Hoey | Bal | mr | 23 | .839 | 53 | .283 | 39 | .513 | 41 | .539 | 11.9 | 6.8 | 6.41 | 6.69 |
| Trevor Hoffman | SD | cl | 38 | .620 | 243 | .251 | 131 | .385 | 131 | .385 | 29.1 | 3.0 | 2.74 | 2.61 |
| J.P. Howell* | Tam | sp | 23 | .835 | 121 | .347 | 87 | .492 | 90 | .508 | 24.6 | 5.4 | 5.02 | 5.82 |
| Bob Howry | ChN | mr | 32 | .692 | 319 | .298 | 184 | .407 | 191 | .423 | 47.9 | 3.9 | 3.55 | 3.21 |
| Jon Huber | Sea | mr | 24 | .744 | 75 | .227 | 46 | .489 | 46 | .489 | 11.3 | 4.6 | 4.16 | 3.82 |
| Luke Hudson | KC | sp | 29 | .846 | 373 | .362 | 239 | .487 | 245 | .499 | 74.7 | 6.2 | 5.62 | 5.98 |
| Tim Hudson | Atl | sp | 30 | .737 | 705 | .285 | 413 | .450 | 417 | .454 | 108.8 | 4.5 | 4.04 | 3.71 |
| Travis Hughes | Was | mr | 28 | 1.319 | 61 | .443 | 63 | .708 | 71 | .798 | 32.6 | 22.0 | 19.33 | 20.91 |
| Jason Isringhausen | StL | cl | 33 | .922 | 176 | .307 | 170 | .569 | 174 | .582 | 54.5 | 8.3 | 7.61 | 8.72 |
| Edwin Jackson | Tam | mr | 22 | .793 | 102 | .353 | 72 | .474 | 73 | .480 | 21.2 | 5.8 | 5.19 | 5.22 |
| Zach Jackson* | Mil | sp | 23 | .822 | 112 | .304 | 78 | .513 | 78 | .513 | 23.9 | 6.3 | 5.92 | 5.38 |
| Chuck James* | Atl | sp | 24 | .825 | 323 | .269 | 259 | .515 | 267 | .531 | 74.7 | 6.0 | 5.37 | 5.43 |
| Casey Janssen | Tor | sp | 24 | .902 | 332 | .271 | 240 | .562 | 246 | .576 | 72.5 | 6.7 | 5.93 | 6.15 |
| Kevin Jarvis |   | mr | 36 | .850 | 93 | .344 | 58 | .479 | 61 | .504 | 19.9 | 6.9 | 6.20 | 5.75 |
| Bobby Jenks | ChA | cl | 25 | .650 | 223 | .363 | 142 | .388 | 144 | .393 | 34.0 | 3.4 | 2.99 | 2.85 |
| Jason Jennings | Col | sp | 27 | .691 | 619 | .281 | 371 | .424 | 374 | .427 | 94.1 | 4.1 | 3.74 | 3.76 |
| Cesar Jimenez* | Sea | mr | 21 | 2.145 | 7 | .286 | 17 | 1.545 | 17 | 1.545 | 7.4 | 33.3 | 35.92 | 39.13 |
| Ubaldo Jimenez | Col | sp | 22 | .926 | 20 | .400 | 15 | .536 | 15 | .536 | 5.4 | 8.1 | 7.27 | 4.83 |
| Jason Johnson |   | mr | 32 | .896 | 332 | .355 | 226 | .534 | 228 | .539 | 70.1 | 6.8 | 6.11 | 6.46 |
| Jim Johnson | Bal | sp | 23 | 1.511 | 7 | .429 | 10 | .909 | 10 | .909 | 5.3 | 35.7 | 32.09 | 36.34 |
| Josh Johnson | Flo | sp | 22 | .778 | 407 | .327 | 301 | .479 | 307 | .488 | 86.4 | 5.5 | 4.99 | 4.61 |
| Randy Johnson* | NYA | sp | 42 | .664 | 577 | .276 | 343 | .406 | 349 | .414 | 86.2 | 3.8 | 3.46 | 3.24 |
| Tyler Johnson* | StL | mr | 25 | .841 | 103 | .350 | 89 | .494 | 95 | .528 | 29.3 | 7.1 | 6.53 | 6.64 |
| Greg Jones | LAA | mr | 29 | .967 | 14 | .429 | 8 | .533 | 8 | .533 | 3.4 | 11.4 | 13.72 | 14.69 |
| Todd Jones | Det | cl | 38 | .711 | 184 | .304 | 92 | .402 | 96 | .419 | 25.7 | 4.2 | 3.81 | 3.77 |
| Jorge Julio |   | cl | 27 | .747 | 144 | .306 | 123 | .468 | 126 | .479 | 33.0 | 5.0 | 4.51 | 4.42 |
| Steve Karsay | Oak | mr | 34 | .787 | 47 | .191 | 30 | .500 | 31 | .517 | 6.4 | 3.8 | 3.47 | 4.22 |
| Jeff Karstens | NYA | sp | 23 | .693 | 138 | .232 | 77 | .448 | 78 | .453 | 19.2 | 4.2 | 3.86 | 2.94 |
| Scott Kazmir* | Tam | sp | 22 | .687 | 330 | .327 | 255 | .430 | 259 | .437 | 64.9 | 4.3 | 3.88 | 3.69 |
| Randy Keisler* | Oak | mr | 30 | 1.173 | 39 | .359 | 42 | .750 | 42 | .750 | 14.7 | 12.0 | 10.51 | 11.49 |
| Joe Kennedy* | Oak | mr | 27 | .684 | 105 | .343 | 57 | .393 | 58 | .400 | 15.6 | 4.2 | 3.88 | 3.99 |
| Logan Kensing | Flo | mr | 23 | .959 | 107 | .308 | 122 | .626 | 125 | .641 | 38.1 | 8.0 | 7.41 | 6.86 |
| Bobby Keppel | KC | sp | 24 | .876 | 108 | .315 | 76 | .531 | 77 | .538 | 24.5 | 7.3 | 6.76 | 7.03 |
| Byung-Hyun Kim | Col | sp | 27 | .829 | 475 | .335 | 336 | .503 | 340 | .509 | 101.3 | 6.1 | 5.49 | 5.00 |
| Sun-Woo Kim |   | mr | 28 | .819 | 49 | .286 | 35 | .522 | 35 | .522 | 10.0 | 6.0 | 5.54 | 5.69 |
| Ray King* | Col | mr | 32 | .855 | 247 | .368 | 167 | .494 | 170 | .503 | 48.3 | 6.0 | 5.44 | 6.99 |
| Josh Kinney | StL | mr | 27 | .626 | 80 | .213 | 47 | .402 | 47 | .402 | 10.8 | 3.4 | 3.09 | 2.75 |
| Steve Kline* | SF | mr | 33 | .798 | 222 | .365 | 150 | .479 | 150 | .479 | 43.8 | 5.8 | 5.34 | 5.61 |
| Dan Kolb | Mil | mr | 31 | .808 | 322 | .320 | 204 | .474 | 207 | .481 | 59.8 | 5.6 | 5.04 | 5.30 |
| Shane Komine | Oak | sp | 25 | .979 | 29 | .172 | 27 | .675 | 27 | .675 | 7.1 | 6.9 | 6.43 | 7.36 |
| John Koronka* | Tex | sp | 25 | .863 | 395 | .329 | 267 | .524 | 270 | .529 | 86.6 | 6.9 | 6.28 | 5.63 |
| Hong-Chih Kuo* | LAN | mr | 24 | .626 | 174 | .316 | 110 | .385 | 110 | .385 | 26.4 | 3.4 | 3.07 | 2.64 |
| John Lackey | LAA | sp | 27 | .749 | 572 | .301 | 390 | .463 | 397 | .471 | 104.3 | 4.8 | 4.31 | 4.25 |
| Juan Lara* | Cle | mr | 25 | .222 | 4 | .000 | 2 | .222 | 2 | .222 | 0.1 | 0.2 | 0.20 | 0.72 |
| Brandon League | Tor | mr | 23 | .520 | 122 | .172 | 57 | .320 | 61 | .343 | 10.9 | 2.1 | 1.87 | 1.61 |
| Wilfredo Ledezma* | Det | mr | 25 | .818 | 207 | .309 | 135 | .504 | 137 | .511 | 41.8 | 6.3 | 5.71 | 5.17 |
| Cliff Lee* | Cle | sp | 27 | .785 | 598 | .324 | 374 | .475 | 375 | .476 | 110.2 | 5.6 | 5.05 | 5.02 |
| Justin Lehr | Mil | mr | 28 | .797 | 29 | .345 | 17 | .486 | 17 | .486 | 5.5 | 6.5 | 6.07 | 4.61 |
| Jon Lester* | Bos | sp | 22 | .753 | 232 | .341 | 152 | .448 | 153 | .451 | 42.8 | 5.1 | 4.51 | 4.73 |
| Colby Lewis | Det | mr | 26 | .619 | 6 | .167 | 3 | .429 | 3 | .429 | 0.0 | 0.0 | 0.00 | 1.62 |
| Brad Lidge | Hou | cl | 29 | .674 | 156 | .321 | 143 | .437 | 145 | .443 | 35.0 | 4.1 | 3.65 | 3.40 |
| Cory Lidle |   | sp | 34 | .817 | 497 | .290 | 359 | .511 | 364 | .519 | 96.4 | 5.3 | 4.83 | 5.05 |
| Jon Lieber | Phi | sp | 36 | .859 | 539 | .325 | 357 | .526 | 359 | .529 | 108.3 | 6.2 | 5.77 | 5.38 |
| Ted Lilly* | Tor | sp | 30 | .834 | 492 | .321 | 389 | .521 | 392 | .525 | 116.5 | 6.4 | 5.77 | 5.43 |
| Jose Lima | NYN | sp | 33 | .962 | 46 | .391 | 35 | .583 | 35 | .583 | 12.6 | 8.9 | 8.26 | 8.21 |
| Scott Linebrink | SD | mr | 29 | .785 | 288 | .330 | 183 | .466 | 185 | .471 | 58.0 | 5.9 | 5.30 | 4.87 |
| Francisco Liriano* | Min | sp | 22 | .508 | 310 | .245 | 174 | .322 | 175 | .323 | 30.5 | 1.9 | 1.75 | 1.67 |
| Wes Littleton | Tex | mr | 23 | .607 | 137 | .241 | 67 | .351 | 72 | .377 | 14.8 | 2.8 | 2.56 | 3.00 |
| Esteban Loaiza | Oak | sp | 34 | .683 | 535 | .267 | 290 | .414 | 296 | .423 | 72.7 | 3.9 | 3.53 | 3.32 |
| Kameron Loe | Tex | sp | 24 | .827 | 291 | .299 | 179 | .507 | 180 | .510 | 50.4 | 5.5 | 5.08 | 5.29 |
| Adam Loewen* | Bal | sp | 22 | .642 | 294 | .310 | 178 | .379 | 183 | .389 | 42.8 | 3.5 | 3.19 | 3.73 |
| Boone Logan* | ChA | mr | 21 | .626 | 61 | .295 | 34 | .354 | 38 | .396 | 8.6 | 3.4 | 3.09 | 2.77 |
| Kyle Lohse |   | sp | 27 | .810 | 394 | .350 | 264 | .481 | 268 | .488 | 79.2 | 5.8 | 5.21 | 5.26 |
| Braden Looper | StL | mr | 31 | .701 | 363 | .292 | 188 | .402 | 196 | .419 | 50.7 | 4.1 | 3.76 | 3.82 |
| Javier Lopez* | Bos | mr | 28 | .461 | 68 | .162 | 32 | .311 | 32 | .311 | 4.4 | 1.4 | 1.27 | 1.44 |
| Rodrigo Lopez | Bal | sp | 30 | .810 | 484 | .316 | 337 | .497 | 341 | .503 | 97.5 | 5.6 | 5.13 | 5.05 |
| Derek Lowe | LAN | sp | 33 | .714 | 681 | .295 | 379 | .424 | 386 | .432 | 100.9 | 4.3 | 3.97 | 3.96 |
| Mark Lowe | Sea | mr | 23 | .606 | 25 | .280 | 15 | .395 | 15 | .395 | 3.4 | 3.2 | 2.92 | 1.85 |
| Noah Lowry* | SF | sp | 25 | .800 | 477 | .289 | 315 | .488 | 319 | .495 | 88.7 | 5.3 | 4.89 | 4.65 |
| Ruddy Lugo | Tam | mr | 26 | .716 | 373 | .276 | 210 | .428 | 217 | .442 | 55.8 | 4.5 | 4.03 | 4.18 |
| Brandon Lyon | Ari | mr | 26 | .806 | 168 | .315 | 114 | .504 | 114 | .504 | 31.8 | 5.5 | 4.95 | 4.68 |
| Mike MacDougal |   | mr | 29 | .697 | 70 | .286 | 42 | .416 | 44 | .436 | 10.7 | 4.0 | 3.67 | 4.03 |
| Greg Maddux |   | sp | 40 | .761 | 660 | .314 | 389 | .457 | 391 | .459 | 105.4 | 4.6 | 4.23 | 4.05 |
| Ryan Madson | Phi | mr | 25 | .901 | 393 | .377 | 296 | .530 | 303 | .542 | 101.3 | 7.7 | 7.01 | 6.82 |
| Ron Mahay* | Tex | mr | 35 | .710 | 174 | .322 | 117 | .427 | 119 | .434 | 30.4 | 4.4 | 3.99 | 4.55 |
| Paul Maholm* | Pit | sp | 24 | .818 | 461 | .317 | 321 | .489 | 329 | .502 | 93.5 | 5.7 | 5.21 | 5.43 |
| John Maine | NYN | sp | 25 | .518 | 241 | .187 | 127 | .340 | 128 | .342 | 23.6 | 2.2 | 2.00 | 1.72 |
| Gary Majewski |   | mr | 26 | .775 | 224 | .308 | 142 | .467 | 145 | .477 | 39.0 | 5.0 | 4.56 | 4.49 |
| Julio Manon | Bal | mr | 32 | 1.008 | 103 | .320 | 97 | .634 | 99 | .647 | 33.7 | 9.9 | 9.09 | 8.97 |
| Shaun Marcum | Tor | sp | 24 | .901 | 223 | .269 | 188 | .577 | 191 | .586 | 56.2 | 7.0 | 6.53 | 6.39 |
| Carlos Marmol | ChN | sp | 23 | .760 | 222 | .225 | 175 | .497 | 177 | .503 | 45.7 | 5.3 | 4.85 | 4.49 |
| Mike Maroth* | Det | sp | 28 | .766 | 214 | .271 | 130 | .478 | 130 | .478 | 36.1 | 5.1 | 4.69 | 4.37 |
| Jason Marquis | StL | sp | 27 | .867 | 552 | .281 | 385 | .533 | 395 | .547 | 117.8 | 6.6 | 5.89 | 5.90 |
| Sean Marshall* | ChN | sp | 23 | .795 | 380 | .324 | 263 | .476 | 270 | .488 | 78.3 | 5.7 | 5.07 | 5.01 |
| Damaso Marte* | Pit | mr | 31 | .731 | 169 | .308 | 133 | .449 | 135 | .456 | 35.6 | 4.8 | 4.33 | 4.49 |
| Tom Martin* | Col | mr | 36 | .707 | 234 | .329 | 129 | .404 | 132 | .414 | 35.5 | 4.4 | 4.01 | 4.33 |
| Carlos Martinez | Flo | mr | 24 | .458 | 29 | .345 | 15 | .254 | 16 | .271 | 3.2 | 1.9 | 1.71 | 1.60 |
| Pedro Martinez | NYN | sp | 34 | .738 | 354 | .251 | 264 | .467 | 272 | .481 | 69.9 | 4.7 | 4.23 | 3.90 |
| Tom Mastny | Cle | cl | 25 | .927 | 94 | .436 | 65 | .516 | 66 | .524 | 25.0 | 9.0 | 8.20 | 8.42 |
| Juan Mateo | ChN | sp | 23 | .907 | 168 | .327 | 127 | .550 | 129 | .558 | 40.7 | 7.4 | 6.68 | 6.17 |
| Julio Mateo | Sea | mr | 28 | .817 | 153 | .327 | 104 | .502 | 104 | .502 | 30.9 | 6.1 | 5.53 | 5.44 |
| Scott Mathieson | Phi | sp | 22 | 1.170 | 98 | .408 | 104 | .743 | 105 | .750 | 40.6 | 13.0 | 11.88 | 10.46 |
| Joe Mays |   | sp | 30 | 1.007 | 137 | .350 | 109 | .612 | 109 | .612 | 37.3 | 9.2 | 8.48 | 9.11 |
| Macay McBride* | Atl | mr | 23 | .873 | 165 | .394 | 149 | .528 | 151 | .535 | 46.2 | 7.6 | 6.69 | 7.41 |
| Brandon McCarthy | ChA | mr | 22 | .749 | 333 | .282 | 228 | .467 | 231 | .473 | 62.2 | 5.0 | 4.47 | 4.33 |
| Seth McClung | Tam | mr | 25 | .860 | 273 | .319 | 204 | .524 | 206 | .530 | 65.0 | 7.3 | 6.53 | 7.12 |
| Dustin McGowan | Tor | mr | 24 | .751 | 75 | .347 | 51 | .451 | 52 | .460 | 14.1 | 5.0 | 4.50 | 4.58 |
| Marty McLeary | Pit | mr | 31 | .832 | 34 | .353 | 23 | .479 | 24 | .500 | 8.0 | 8.0 | 7.24 | 7.51 |
| Brian Meadows | Tam | mr | 30 | .874 | 411 | .321 | 274 | .538 | 275 | .540 | 82.7 | 6.4 | 5.86 | 5.84 |
| Gil Meche | Sea | sp | 27 | .769 | 526 | .283 | 374 | .487 | 377 | .491 | 99.8 | 5.1 | 4.62 | 4.70 |
| Brandon Medders | Ari | mr | 26 | .724 | 273 | .311 | 166 | .431 | 169 | .439 | 45.4 | 4.7 | 4.23 | 4.26 |
| Kent Mercker* | Cin | mr | 38 | .696 | 150 | .260 | 86 | .424 | 88 | .433 | 21.6 | 4.1 | 3.72 | 3.77 |
| Cla Meredith | SD | mr | 23 | .544 | 120 | .200 | 51 | .323 | 54 | .342 | 9.9 | 2.1 | 1.97 | 1.85 |
| Jose Mesa | Col | mr | 40 | .731 | 271 | .277 | 175 | .440 | 182 | .457 | 44.9 | 4.5 | 4.09 | 4.75 |
| Randy Messenger | Flo | mr | 24 | .844 | 124 | .274 | 94 | .547 | 94 | .547 | 26.0 | 5.9 | 5.41 | 5.77 |
| Dan Miceli | Tam | mr | 35 | .468 | 103 | .165 | 43 | .305 | 44 | .312 | 7.6 | 1.9 | 1.86 | 1.69 |
| Chris Michalak* | Cin | sp | 35 | .998 | 96 | .385 | 71 | .582 | 72 | .590 | 27.7 | 10.7 | 9.75 | 9.33 |
| Andrew Miller* | Det | mr | 21 | .763 | 18 | .222 | 16 | .533 | 16 | .533 | 3.9 | 7.1 | 7.35 | 10.48 |
| Matt Miller | Cle | mr | 34 | 1.345 | 6 | .333 | 13 | .929 | 13 | .929 | 4.9 | 16.7 | 15.00 | 14.59 |
| Trever Miller* | Hou | mr | 33 | .674 | 168 | .262 | 113 | .417 | 116 | .428 | 27.1 | 3.6 | 3.34 | 3.03 |
| Wade Miller | ChN | sp | 29 | .710 | 70 | .271 | 49 | .434 | 51 | .451 | 13.8 | 5.2 | 4.85 | 5.41 |
| Kevin Millwood | Tex | sp | 31 | .741 | 630 | .322 | 367 | .436 | 374 | .445 | 102.5 | 4.7 | 4.16 | 4.06 |
| Eric Milton* | Cin | sp | 30 | .751 | 515 | .297 | 306 | .455 | 308 | .458 | 85.7 | 4.9 | 4.53 | 4.20 |
| Zach Miner | Det | sp | 24 | .837 | 313 | .307 | 207 | .517 | 208 | .520 | 60.1 | 5.9 | 5.39 | 5.15 |
| Sergio Mitre | Flo | sp | 25 | .793 | 154 | .266 | 111 | .476 | 117 | .502 | 30.3 | 5.1 | 4.73 | 4.90 |
| Brian Moehler | Flo | sp | 34 | .877 | 411 | .326 | 285 | .524 | 294 | .540 | 89.6 | 6.7 | 6.12 | 6.17 |
| Agustin Montero | ChA | mr | 28 | .629 | 62 | .145 | 32 | .421 | 33 | .434 | 5.4 | 2.3 | 2.08 | 2.05 |
| Juan Morillo | Col | sp | 22 | 1.049 | 22 | .364 | 20 | .667 | 20 | .667 | 7.2 | 11.4 | 10.23 | 8.81 |
| Matt Morris | SF | sp | 31 | .734 | 612 | .271 | 353 | .440 | 367 | .458 | 99.7 | 4.8 | 4.33 | 3.87 |
| Dustin Moseley | LAA | sp | 24 | .901 | 29 | .379 | 19 | .543 | 19 | .543 | 6.3 | 7.5 | 7.01 | 6.66 |
| Guillermo Mota |   | mr | 32 | .675 | 228 | .285 | 145 | .426 | 146 | .429 | 34.8 | 3.8 | 3.37 | 2.90 |
| Jamie Moyer* |   | sp | 43 | .847 | 651 | .275 | 457 | .539 | 461 | .544 | 129.6 | 6.0 | 5.39 | 5.14 |
| Peter Moylan | Atl | mr | 27 | .782 | 69 | .377 | 52 | .491 | 52 | .491 | 14.2 | 5.1 | 4.55 | 3.88 |
| Edward Mujica | Cle | mr | 22 | .689 | 62 | .371 | 28 | .359 | 29 | .372 | 8.3 | 4.0 | 3.59 | 4.05 |
| Mark Mulder* | StL | sp | 28 | 1.029 | 269 | .320 | 236 | .643 | 237 | .646 | 80.5 | 9.4 | 8.47 | 8.61 |
| Terry Mulholland* | Ari | mr | 43 | 1.300 | 8 | .500 | 8 | .727 | 8 | .727 | 3.9 | 17.4 | 18.82 | 19.14 |
| Scott Munter | SF | mr | 26 | 1.006 | 76 | .382 | 63 | .606 | 64 | .615 | 22.2 | 9.8 | 8.84 | 8.71 |
| Mike Mussina | NYA | sp | 37 | .655 | 588 | .306 | 343 | .398 | 346 | .401 | 81.6 | 3.4 | 3.13 | 3.05 |
| Brett Myers | Phi | sp | 25 | .739 | 517 | .280 | 375 | .469 | 378 | .473 | 90.9 | 4.2 | 3.78 | 3.74 |
| Mike Myers* | NYA | mr | 37 | .724 | 186 | .285 | 108 | .429 | 114 | .452 | 28.4 | 4.3 | 4.06 | 4.26 |
| Chris Narveson* | StL | mr | 24 | .679 | 8 | .500 | 9 | .429 | 9 | .429 | 2.3 | 5.1 | 4.60 | 6.45 |
| Joe Nathan | Min | cl | 31 | .541 | 158 | .291 | 110 | .345 | 112 | .351 | 21.8 | 2.3 | 2.11 | 1.64 |
| Jeff Nelson | ChA | mr | 39 | .664 | 15 | .400 | 8 | .364 | 8 | .364 | 2.6 | 4.9 | 4.44 | 4.93 |
| Joe Nelson | KC | mr | 31 | .816 | 95 | .326 | 82 | .516 | 82 | .516 | 23.1 | 5.9 | 5.29 | 5.05 |
| Pat Neshek | Min | mr | 25 | .672 | 56 | .250 | 45 | .446 | 45 | .446 | 9.7 | 3.4 | 3.10 | 3.08 |
| Fernando Nieve | Hou | mr | 23 | .674 | 245 | .204 | 155 | .434 | 159 | .445 | 33.3 | 3.3 | 3.00 | 2.82 |
| Dustin Nippert | Ari | sp | 25 | 1.602 | 15 | .400 | 29 | 1.074 | 29 | 1.074 | 12.9 | 24.9 | 22.38 | 25.62 |
| Ricky Nolasco | Flo | sp | 23 | .791 | 459 | .307 | 284 | .463 | 292 | .476 | 83.7 | 5.4 | 4.96 | 4.72 |
| Roberto Novoa | ChN | mr | 26 | .806 | 254 | .295 | 179 | .492 | 184 | .505 | 53.3 | 5.9 | 5.37 | 5.11 |
| Leo Nunez | KC | mr | 22 | .822 | 51 | .353 | 36 | .462 | 39 | .500 | 10.5 | 5.3 | 4.80 | 5.87 |
| Mike O'Connor* | Was | sp | 25 | .734 | 345 | .252 | 220 | .462 | 223 | .468 | 57.2 | 4.7 | 4.19 | 4.18 |
| Eric O'Flaherty* | Sea | mr | 21 | 1.209 | 51 | .431 | 46 | .697 | 46 | .697 | 20.8 | 16.5 | 14.87 | 14.09 |
| Ryan O'Malley* | ChN | sp | 26 | .675 | 35 | .114 | 25 | .424 | 27 | .458 | 6.4 | 4.5 | 4.20 | 4.34 |
| Tomo Ohka | Mil | sp | 30 | .710 | 358 | .254 | 208 | .439 | 211 | .445 | 53.1 | 4.3 | 3.87 | 3.79 |
| Will Ohman* | ChN | mr | 28 | .731 | 227 | .247 | 177 | .465 | 182 | .478 | 46.7 | 4.9 | 4.45 | 4.50 |
| Darren Oliver* | NYN | mr | 35 | .629 | 279 | .211 | 158 | .395 | 161 | .403 | 34.1 | 3.0 | 2.78 | 2.65 |
| Scott Olsen* | Flo | sp | 22 | .776 | 522 | .289 | 384 | .490 | 390 | .497 | 100.2 | 4.9 | 4.42 | 4.34 |
| Ramon Ortiz | Was | sp | 33 | .839 | 618 | .320 | 409 | .493 | 425 | .513 | 128.3 | 6.3 | 5.73 | 5.94 |
| Russ Ortiz |   | sp | 32 | 1.168 | 225 | .338 | 271 | .749 | 274 | .757 | 97.7 | 12.2 | 11.09 | 11.61 |
| Chad Orvella | Tam | mr | 25 | 1.018 | 95 | .347 | 91 | .636 | 92 | .643 | 31.3 | 9.8 | 8.95 | 8.29 |
| Franquelis Osoria | LAN | mr | 24 | 1.042 | 71 | .380 | 64 | .627 | 64 | .627 | 21.7 | 9.6 | 8.78 | 10.89 |
| Roy Oswalt | Hou | sp | 28 | .711 | 616 | .307 | 341 | .416 | 350 | .427 | 87.9 | 4.0 | 3.58 | 3.56 |
| Akinori Otsuka | Tex | cl | 34 | .640 | 251 | .319 | 133 | .373 | 134 | .375 | 30.9 | 3.1 | 2.77 | 2.93 |
| Vicente Padilla | Tex | sp | 28 | .795 | 618 | .307 | 415 | .483 | 429 | .499 | 118.5 | 5.4 | 4.92 | 4.80 |
| Jonathan Papelbon | Bos | cl | 25 | .572 | 196 | .255 | 109 | .356 | 111 | .363 | 23.0 | 2.6 | 2.38 | 1.93 |
| Chan Ho Park | SD | sp | 33 | .907 | 355 | .358 | 264 | .553 | 267 | .560 | 85.5 | 7.3 | 6.62 | 6.17 |
| Chad Paronto | Atl | mr | 30 | .750 | 182 | .319 | 115 | .444 | 116 | .448 | 33.5 | 5.1 | 4.70 | 4.85 |
| John Patterson | Was | sp | 28 | .668 | 113 | .301 | 77 | .403 | 80 | .419 | 20.2 | 4.0 | 3.53 | 3.29 |
| David Pauley | Bos | sp | 23 | .940 | 54 | .407 | 36 | .554 | 36 | .554 | 11.5 | 7.2 | 6.67 | 7.55 |
| Jake Peavy | SD | sp | 25 | .722 | 564 | .301 | 390 | .447 | 396 | .454 | 102.1 | 4.4 | 3.98 | 3.33 |
| Mike Pelfrey | NYN | sp | 22 | 1.054 | 48 | .500 | 47 | .603 | 49 | .628 | 16.8 | 10.1 | 9.06 | 11.63 |
| Tony Pena | Ari | mr | 24 | .955 | 90 | .311 | 78 | .605 | 78 | .605 | 23.4 | 7.3 | 6.61 | 6.66 |
| Hayden Penn | Bal | sp | 21 | 1.409 | 64 | .422 | 76 | .874 | 77 | .885 | 35.6 | 22.4 | 20.61 | 21.46 |
| Brad Penny | LAN | sp | 28 | .763 | 568 | .329 | 353 | .454 | 359 | .461 | 98.8 | 4.8 | 4.37 | 4.25 |
| Joel Peralta | KC | mr | 30 | .713 | 201 | .303 | 128 | .437 | 131 | .447 | 33.4 | 4.4 | 3.90 | 3.41 |
| Beltran Perez | Was | mr | 24 | .856 | 43 | .186 | 38 | .585 | 38 | .585 | 10.2 | 6.3 | 5.91 | 6.23 |
| Juan Perez* | Pit | mr | 27 | 1.222 | 30 | .467 | 30 | .652 | 34 | .739 | 13.2 | 16.2 | 14.60 | 16.25 |
| Odalis Perez* |   | mr | 29 | .886 | 384 | .323 | 269 | .543 | 272 | .549 | 85.6 | 7.0 | 6.50 | 5.98 |
| Oliver Perez* |   | sp | 24 | .807 | 265 | .355 | 219 | .479 | 229 | .501 | 65.0 | 6.3 | 5.61 | 6.40 |
| Rafael Perez* | Cle | mr | 24 | .684 | 63 | .333 | 41 | .402 | 42 | .412 | 11.8 | 4.8 | 4.42 | 4.52 |
| Yusmeiro Petit | Flo | mr | 21 | 1.073 | 141 | .411 | 128 | .667 | 129 | .672 | 48.0 | 10.8 | 9.88 | 8.98 |
| Andy Pettitte* | Hou | sp | 34 | .877 | 542 | .334 | 447 | .540 | 455 | .550 | 128.9 | 6.2 | 5.56 | 5.84 |
| Joel Pineiro | Sea | sp | 27 | .889 | 482 | .317 | 353 | .546 | 362 | .560 | 108.3 | 6.8 | 6.06 | 6.22 |
| Renyel Pinto* | Flo | mr | 23 | .851 | 62 | .435 | 72 | .529 | 74 | .544 | 20.2 | 6.6 | 5.98 | 7.13 |
| Cliff Politte | ChA | mr | 32 | 1.098 | 62 | .339 | 60 | .714 | 61 | .726 | 21.2 | 10.8 | 9.35 | 8.41 |
| Sidney Ponson |   | sp | 29 | .837 | 261 | .356 | 175 | .493 | 179 | .504 | 52.1 | 5.9 | 5.29 | 5.65 |
| Mark Prior | ChN | sp | 25 | .817 | 132 | .220 | 108 | .507 | 116 | .545 | 31.8 | 5.9 | 5.40 | 5.00 |
| Scott Proctor | NYA | mr | 29 | .656 | 282 | .294 | 159 | .390 | 164 | .402 | 40.4 | 3.7 | 3.29 | 3.08 |
| J.J. Putz | Sea | cl | 29 | .471 | 196 | .276 | 84 | .272 | 85 | .275 | 14.5 | 1.6 | 1.40 | 1.36 |
| Chad Qualls | Hou | mr | 27 | .692 | 283 | .279 | 164 | .414 | 168 | .424 | 37.2 | 3.4 | 3.00 | 3.34 |
| Brad Radke | Min | sp | 33 | .909 | 536 | .351 | 378 | .553 | 381 | .557 | 121.2 | 7.1 | 6.39 | 6.37 |
| Elizardo Ramirez | Cin | sp | 23 | .900 | 297 | .350 | 210 | .525 | 218 | .545 | 69.2 | 7.2 | 6.60 | 6.79 |
| Horacio Ramirez* | Atl | sp | 26 | .760 | 269 | .331 | 147 | .424 | 153 | .441 | 44.7 | 5.2 | 4.62 | 5.08 |
| Ramon Ramirez | Col | mr | 24 | .745 | 208 | .313 | 149 | .467 | 150 | .470 | 39.5 | 4.9 | 4.43 | 3.93 |
| Darrell Rasner | NYA | sp | 25 | .842 | 53 | .226 | 36 | .522 | 39 | .565 | 10.7 | 6.2 | 5.66 | 5.03 |
| Jon Rauch | Was | mr | 27 | .765 | 272 | .283 | 209 | .483 | 210 | .485 | 58.6 | 5.4 | 4.96 | 4.77 |
| Chris Ray | Bal | cl | 24 | .718 | 232 | .216 | 170 | .472 | 171 | .475 | 41.0 | 4.3 | 3.91 | 3.98 |
| Ken Ray | Atl | mr | 31 | .715 | 217 | .258 | 161 | .457 | 163 | .463 | 41.1 | 4.6 | 4.18 | 4.03 |
| Britt Reames | Pit | mr | 32 | 1.284 | 32 | .406 | 38 | .792 | 38 | .792 | 15.3 | 15.3 | 13.25 | 12.90 |
| Mark Redman* | KC | sp | 32 | .787 | 547 | .291 | 335 | .486 | 336 | .487 | 91.6 | 5.3 | 4.78 | 4.78 |
| Chris Reitsma | Atl | cl | 28 | 1.062 | 151 | .331 | 124 | .639 | 131 | .675 | 47.0 | 10.5 | 9.77 | 9.23 |
| Mike Remlinger* | Atl | mr | 40 | .661 | 71 | .324 | 38 | .355 | 42 | .393 | 10.1 | 3.8 | 3.50 | 4.36 |
| Chris Resop | Flo | mr | 23 | .773 | 105 | .314 | 63 | .450 | 65 | .464 | 18.4 | 5.3 | 4.86 | 4.56 |
| Anthony Reyes | StL | sp | 24 | .720 | 262 | .225 | 185 | .460 | 191 | .475 | 46.6 | 4.3 | 3.92 | 3.53 |
| Dennys Reyes* | Min | mr | 29 | .600 | 147 | .299 | 74 | .351 | 75 | .355 | 16.2 | 2.8 | 2.55 | 2.61 |
| John Rheinecker* | Tex | sp | 27 | .841 | 276 | .312 | 172 | .513 | 174 | .519 | 51.7 | 6.2 | 5.69 | 5.40 |
| Arthur Rhodes* | Phi | mr | 36 | .875 | 219 | .416 | 171 | .514 | 174 | .523 | 57.6 | 7.4 | 6.48 | 5.86 |
| Juan Rincon | Min | mr | 27 | .594 | 268 | .291 | 131 | .340 | 136 | .353 | 30.0 | 2.8 | 2.53 | 2.49 |
| Ricardo Rincon* | StL | mr | 36 | .980 | 14 | .286 | 13 | .520 | 16 | .640 | 4.8 | 9.2 | 8.26 | 10.50 |
| Royce Ring* | NYN | mr | 25 | .931 | 41 | .195 | 36 | .632 | 36 | .632 | 10.4 | 7.6 | 6.82 | 6.88 |
| David Riske |   | mr | 29 | .717 | 202 | .317 | 118 | .420 | 121 | .431 | 31.2 | 4.3 | 3.86 | 4.12 |
| Mariano Rivera | NYA | cl | 36 | .543 | 220 | .259 | 94 | .305 | 98 | .318 | 18.4 | 2.0 | 1.81 | 1.85 |
| Saul Rivera | Was | mr | 28 | .678 | 231 | .294 | 129 | .397 | 133 | .409 | 35.7 | 4.5 | 4.07 | 4.31 |
| Sendy Rleal | Bal | mr | 26 | .895 | 145 | .269 | 125 | .573 | 127 | .583 | 37.7 | 7.2 | 6.54 | 6.40 |
| Nate Robertson* | Det | sp | 28 | .763 | 654 | .283 | 400 | .461 | 415 | .478 | 104.5 | 4.6 | 4.16 | 4.51 |
| Fernando Rodney | Det | mr | 29 | .743 | 183 | .257 | 128 | .446 | 138 | .481 | 34.1 | 4.5 | 4.16 | 4.05 |
| Eddy Rodriguez | Bal | mr | 24 | .966 | 34 | .294 | 28 | .609 | 28 | .609 | 9.7 | 9.4 | 8.43 | 8.74 |
| Felix Rodriguez | Was | mr | 33 | .832 | 67 | .239 | 54 | .509 | 57 | .538 | 16.7 | 6.9 | 6.23 | 5.74 |
| Francisco Rodriguez | LAA | cl | 24 | .507 | 174 | .230 | 90 | .325 | 90 | .325 | 17.0 | 2.1 | 1.89 | 1.45 |
| Wandy Rodriguez* | Hou | sp | 27 | .939 | 324 | .324 | 293 | .591 | 296 | .597 | 92.5 | 8.0 | 7.16 | 7.24 |
| Brian Rogers | Pit | mr | 23 | .870 | 35 | .286 | 29 | .547 | 29 | .547 | 8.5 | 6.2 | 5.73 | 5.24 |
| Kenny Rogers* | Det | sp | 41 | .678 | 728 | .261 | 375 | .408 | 386 | .420 | 93.6 | 3.8 | 3.47 | 3.45 |
| Davis Romero* | Tor | mr | 23 | 1.044 | 52 | .423 | 47 | .627 | 47 | .627 | 16.6 | 10.2 | 8.96 | 9.57 |
| J.C. Romero* | LAA | mr | 30 | .813 | 166 | .337 | 109 | .491 | 111 | .500 | 34.0 | 6.5 | 6.17 | 5.62 |
| Francisco Rosario | Tor | mr | 25 | 1.018 | 80 | .350 | 89 | .650 | 90 | .657 | 31.3 | 10.4 | 9.27 | 9.59 |
| Josh Rupe | Tex | mr | 23 | .829 | 166 | .367 | 88 | .451 | 92 | .472 | 27.4 | 5.7 | 5.20 | 6.38 |
| Glendon Rusch* | ChN | mr | 31 | .988 | 146 | .308 | 163 | .642 | 164 | .646 | 48.6 | 7.8 | 7.07 | 7.74 |
| B.J. Ryan* | Tor | cl | 30 | .382 | 173 | .208 | 74 | .239 | 76 | .245 | 10.7 | 1.2 | 1.05 | 1.15 |
| Jae Kuk Ryu | ChN | mr | 23 | 1.373 | 31 | .387 | 48 | .906 | 49 | .925 | 20.8 | 18.7 | 16.81 | 16.45 |
| Kirk Saarloos | Oak | mr | 27 | .814 | 441 | .277 | 280 | .505 | 283 | .510 | 81.2 | 5.8 | 5.22 | 5.09 |
| C.C. Sabathia* | Cle | sp | 25 | .655 | 526 | .291 | 301 | .399 | 305 | .404 | 72.0 | 3.4 | 3.13 | 2.84 |
| Takashi Saito | LAN | cl | 36 | .508 | 174 | .259 | 103 | .313 | 105 | .319 | 19.6 | 2.1 | 1.86 | 1.70 |
| Juan Salas | Tam | mr | 27 | 1.050 | 35 | .371 | 30 | .652 | 30 | .652 | 11.3 | 11.8 | 10.60 | 9.12 |
| Chris Sampson | Hou | mr | 28 | .366 | 112 | .134 | 31 | .228 | 31 | .228 | 4.5 | 1.0 | 0.95 | 0.71 |
| Brian Sanches | Phi | mr | 27 | .822 | 69 | .333 | 55 | .524 | 55 | .524 | 15.1 | 5.7 | 4.97 | 4.55 |
| Anibal Sanchez | Flo | sp | 22 | .693 | 325 | .286 | 191 | .418 | 194 | .425 | 50.7 | 4.2 | 3.89 | 3.62 |
| Duaner Sanchez | NYN | mr | 26 | .565 | 163 | .252 | 83 | .339 | 87 | .355 | 15.7 | 2.2 | 2.02 | 2.06 |
| Jonathan Sanchez* | SF | mr | 23 | .629 | 93 | .247 | 60 | .382 | 63 | .401 | 15.2 | 3.7 | 3.28 | 2.98 |
| Ervin Santana | LAA | sp | 23 | .760 | 601 | .268 | 393 | .467 | 407 | .484 | 105.6 | 4.8 | 4.34 | 4.15 |
| Johan Santana* | Min | sp | 27 | .618 | 571 | .284 | 353 | .388 | 356 | .391 | 80.8 | 3.2 | 2.90 | 2.42 |
| Julio Santana | Phi | mr | 33 | .000 | 2 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Victor Santos | Pit | sp | 29 | .894 | 440 | .348 | 310 | .526 | 320 | .543 | 99.4 | 6.8 | 6.19 | 6.09 |
| Dennis Sarfate | Mil | mr | 25 | 1.000 | 2 | .500 | 1 | .500 | 1 | .500 | 0.5 | 13.5 | 12.15 | 14.52 |
| Scott Sauerbeck* |   | mr | 34 | .857 | 111 | .261 | 87 | .489 | 100 | .562 | 27.5 | 6.6 | 6.14 | 5.94 |
| Joe Saunders* | LAA | sp | 25 | .753 | 231 | .333 | 143 | .450 | 145 | .456 | 37.8 | 4.6 | 4.29 | 4.71 |
| Curt Schilling | Bos | sp | 39 | .820 | 550 | .335 | 396 | .515 | 398 | .518 | 111.4 | 5.5 | 5.01 | 4.56 |
| Jason Schmidt | SF | sp | 33 | .711 | 584 | .295 | 378 | .441 | 380 | .443 | 97.0 | 4.2 | 3.81 | 3.63 |
| Scott Schoeneweis* |   | mr | 32 | .792 | 184 | .293 | 117 | .478 | 119 | .486 | 33.4 | 5.4 | 4.90 | 5.15 |
| Chris Schroder | Was | mr | 27 | .853 | 54 | .222 | 64 | .593 | 65 | .602 | 16.8 | 6.0 | 5.39 | 4.87 |
| Rudy Seanez |   | mr | 37 | .799 | 169 | .361 | 114 | .469 | 115 | .473 | 36.4 | 6.3 | 5.60 | 5.71 |
| Bobby Seay* | Det | mr | 28 | .535 | 61 | .262 | 27 | .307 | 29 | .330 | 5.9 | 2.4 | 2.14 | 1.90 |
| Aaron Sele | LAN | sp | 36 | .802 | 384 | .297 | 234 | .485 | 236 | .490 | 70.3 | 5.8 | 5.24 | 4.57 |
| Jae Seo |   | sp | 29 | .935 | 441 | .322 | 353 | .588 | 357 | .595 | 113.5 | 7.9 | 7.16 | 7.12 |
| Brian Shackelford* | Cin | mr | 29 | .954 | 56 | .250 | 55 | .640 | 55 | .640 | 15.7 | 7.3 | 6.92 | 6.96 |
| Josh Sharpless | Pit | mr | 25 | .548 | 45 | .200 | 28 | .364 | 28 | .364 | 6.2 | 3.1 | 2.88 | 2.65 |
| Ben Sheets | Mil | sp | 27 | .754 | 296 | .311 | 215 | .466 | 221 | .479 | 56.6 | 4.5 | 4.16 | 3.67 |
| George Sherrill* | Sea | mr | 29 | .736 | 150 | .347 | 118 | .456 | 119 | .459 | 32.1 | 5.3 | 4.78 | 5.43 |
| James Shields | Tam | sp | 24 | .852 | 370 | .351 | 259 | .500 | 269 | .519 | 83.0 | 6.6 | 5.97 | 6.17 |
| Scot Shields | LAA | mr | 30 | .643 | 262 | .263 | 157 | .401 | 159 | .406 | 36.1 | 3.3 | 2.96 | 2.80 |
| Jason Shiell | Atl | sp | 29 | 1.263 | 24 | .333 | 33 | .767 | 34 | .791 | 13.2 | 14.3 | 12.87 | 11.44 |
| Brian Shouse* |   | mr | 37 | .785 | 171 | .275 | 108 | .464 | 113 | .485 | 29.4 | 4.9 | 4.50 | 4.98 |
| Brian Sikorski |   | mr | 31 | .729 | 51 | .196 | 43 | .494 | 44 | .506 | 9.7 | 3.9 | 3.56 | 3.22 |
| Carlos Silva | Min | sp | 27 | .952 | 590 | .332 | 420 | .581 | 427 | .591 | 139.0 | 7.9 | 7.13 | 7.40 |
| Andrew Sisco* | KC | mr | 23 | .847 | 195 | .374 | 144 | .502 | 146 | .509 | 46.6 | 7.1 | 6.22 | 6.54 |
| Doug Slaten* | Ari | mr | 26 | .316 | 17 | .176 | 3 | .158 | 3 | .158 | 0.5 | 0.8 | 0.72 | 0.67 |
| Brian Slocum | Cle | mr | 25 | 1.385 | 30 | .500 | 33 | .805 | 34 | .829 | 17.2 | 25.7 | 23.17 | 22.36 |
| Aaron Small | NYA | mr | 34 | .876 | 63 | .222 | 51 | .586 | 51 | .586 | 14.1 | 6.6 | 5.92 | 6.01 |
| Matt Smith* |   | mr | 27 | .517 | 76 | .237 | 44 | .328 | 45 | .336 | 8.3 | 2.2 | 2.01 | 1.93 |
| Mike Smith | Min | sp | 28 | 1.361 | 5 | .800 | 8 | .667 | 10 | .833 | 4.5 | 24.5 | 18.38 | 15.58 |
| Travis Smith | Atl | sp | 33 | 1.417 | 8 | .500 | 10 | .833 | 10 | .833 | 4.9 | 32.8 | 29.57 | 27.11 |
| John Smoltz | Atl | sp | 39 | .708 | 614 | .305 | 402 | .433 | 410 | .442 | 103.2 | 4.2 | 3.78 | 3.55 |
| Ian Snell | Pit | sp | 24 | .829 | 494 | .344 | 374 | .509 | 377 | .513 | 114.3 | 6.3 | 5.64 | 5.37 |
| Kyle Snyder |   | sp | 28 | .979 | 225 | .387 | 186 | .600 | 189 | .610 | 64.8 | 8.9 | 7.92 | 7.76 |
| Alay Soler | NYN | sp | 26 | .742 | 143 | .245 | 88 | .461 | 89 | .466 | 25.4 | 5.4 | 4.93 | 4.83 |
| Rafael Soriano | Sea | mr | 26 | .495 | 190 | .221 | 88 | .298 | 92 | .312 | 18.5 | 2.2 | 2.02 | 1.62 |
| Jorge Sosa |   | mr | 29 | .769 | 416 | .264 | 261 | .481 | 263 | .484 | 69.3 | 4.8 | 4.43 | 4.15 |
| Jeremy Sowers* | Cle | sp | 23 | .552 | 325 | .231 | 130 | .325 | 133 | .333 | 27.1 | 2.4 | 2.18 | 2.18 |
| Justin Speier | Tor | mr | 32 | .623 | 230 | .243 | 140 | .393 | 144 | .404 | 33.5 | 3.4 | 3.09 | 2.45 |
| Russ Springer | Hou | mr | 37 | .659 | 232 | .211 | 143 | .421 | 146 | .429 | 33.2 | 3.6 | 3.27 | 3.08 |
| Chris Spurling |   | mr | 29 | .551 | 51 | .196 | 21 | .333 | 22 | .349 | 4.2 | 2.4 | 2.16 | 2.24 |
| Jason Standridge | Cin | mr | 27 | .890 | 74 | .378 | 68 | .544 | 69 | .552 | 22.2 | 8.4 | 7.59 | 9.24 |
| Mike Stanton* |   | cl | 39 | .693 | 282 | .301 | 150 | .398 | 152 | .403 | 41.5 | 4.3 | 3.82 | 3.36 |
| Tim Stauffer | SD | sp | 24 | .471 | 21 | .238 | 7 | .259 | 7 | .259 | 1.3 | 1.5 | 1.45 | 1.32 |
| Steve Stemle | KC | mr | 29 | 1.169 | 39 | .462 | 36 | .720 | 36 | .720 | 15.8 | 16.4 | 14.72 | 12.63 |
| Brian Stokes | Tam | sp | 26 | 1.051 | 49 | .388 | 48 | .632 | 50 | .658 | 17.4 | 10.7 | 9.41 | 9.66 |
| Huston Street | Oak | cl | 22 | .606 | 242 | .314 | 125 | .357 | 125 | .357 | 29.6 | 3.1 | 2.82 | 2.43 |
| Eric Stults* | LAN | mr | 26 | .735 | 50 | .220 | 29 | .483 | 29 | .483 | 6.8 | 4.1 | 3.69 | 2.81 |
| Tanyon Sturtze | NYA | mr | 35 | .807 | 33 | .303 | 20 | .488 | 20 | .488 | 6.8 | 7.3 | 6.85 | 7.14 |
| Jeff Suppan | StL | sp | 31 | .769 | 593 | .285 | 369 | .469 | 378 | .480 | 97.7 | 4.7 | 4.27 | 4.06 |
| Brian Sweeney | SD | mr | 32 | .727 | 201 | .269 | 111 | .432 | 113 | .440 | 31.0 | 4.8 | 4.35 | 4.34 |
| Jon Switzer* | Tam | mr | 26 | .747 | 134 | .306 | 81 | .443 | 83 | .454 | 22.5 | 5.1 | 4.67 | 5.12 |
| Brian Tallet* | Tor | mr | 28 | .651 | 141 | .255 | 83 | .407 | 85 | .417 | 20.1 | 3.7 | 3.30 | 2.78 |
| Taylor Tankersley* | Flo | mr | 23 | .681 | 129 | .357 | 103 | .422 | 104 | .426 | 25.6 | 4.2 | 3.74 | 4.15 |
| Jack Taschner* | SF | mr | 28 | 1.258 | 59 | .424 | 57 | .760 | 57 | .760 | 24.4 | 16.5 | 14.84 | 15.60 |
| Jordan Tata | Det | mr | 24 | .552 | 97 | .237 | 38 | .325 | 38 | .325 | 7.9 | 2.5 | 2.33 | 2.87 |
| Ty Taubenheim | Tor | sp | 23 | 1.008 | 110 | .336 | 97 | .622 | 99 | .635 | 34.2 | 9.8 | 8.94 | 8.17 |
| Julian Tavarez | Bos | mr | 33 | .768 | 383 | .290 | 248 | .470 | 255 | .483 | 63.8 | 4.7 | 4.15 | 4.55 |
| Robinson Tejeda | Tex | sp | 24 | .821 | 231 | .286 | 160 | .498 | 162 | .505 | 48.8 | 6.3 | 5.64 | 5.78 |
| Brad Thompson | StL | mr | 24 | .763 | 145 | .317 | 88 | .433 | 94 | .463 | 22.7 | 4.2 | 3.78 | 4.41 |
| Mike Thompson | SD | sp | 25 | .822 | 324 | .318 | 192 | .485 | 196 | .495 | 58.4 | 5.8 | 5.26 | 5.11 |
| John Thomson | Atl | sp | 32 | .869 | 304 | .280 | 216 | .541 | 216 | .541 | 67.0 | 6.7 | 6.12 | 5.67 |
| Matt Thornton* | ChA | mr | 29 | .722 | 193 | .275 | 127 | .458 | 127 | .458 | 32.1 | 4.4 | 3.98 | 3.79 |
| Mike Timlin | Bos | mr | 40 | .771 | 349 | .341 | 185 | .439 | 187 | .444 | 57.3 | 5.4 | 4.79 | 4.55 |
| Brett Tomko | LAN | mr | 33 | .801 | 376 | .303 | 264 | .499 | 266 | .503 | 73.7 | 5.3 | 4.74 | 4.27 |
| Salomon Torres | Pit | mr | 34 | .842 | 278 | .392 | 183 | .473 | 190 | .491 | 59.5 | 6.4 | 5.88 | 6.23 |
| Josh Towers | Tor | sp | 29 | .965 | 166 | .349 | 135 | .592 | 137 | .601 | 47.8 | 9.1 | 8.17 | 8.31 |
| Billy Traber* | Was | sp | 26 | .916 | 139 | .345 | 97 | .503 | 108 | .560 | 35.4 | 8.1 | 7.55 | 7.72 |
| Sean Tracey | ChA | mr | 25 | .677 | 28 | .250 | 16 | .364 | 19 | .432 | 4.1 | 4.0 | 3.59 | 4.51 |
| Steve Trachsel | NYN | sp | 35 | .847 | 493 | .306 | 326 | .502 | 337 | .519 | 102.1 | 6.5 | 5.95 | 6.01 |
| Derrick Turnbow | Mil | cl | 28 | .939 | 130 | .400 | 145 | .578 | 148 | .590 | 46.3 | 8.1 | 7.16 | 7.75 |
| Jose Valverde | Ari | cl | 26 | .852 | 86 | .360 | 84 | .528 | 84 | .528 | 24.6 | 6.3 | 5.74 | 6.03 |
| Jermaine Van Buren | Bos | mr | 25 | .848 | 52 | .365 | 43 | .524 | 43 | .524 | 13.3 | 7.8 | 7.32 | 7.80 |
| Claudio Vargas | Ari | sp | 28 | .828 | 534 | .290 | 371 | .518 | 374 | .522 | 110.1 | 6.1 | 5.56 | 5.10 |
| Jason Vargas* | Flo | mr | 23 | .942 | 120 | .325 | 110 | .601 | 112 | .612 | 34.5 | 7.9 | 7.36 | 6.67 |
| Javier Vazquez | ChA | sp | 29 | .707 | 627 | .303 | 373 | .421 | 387 | .436 | 96.5 | 4.1 | 3.62 | 3.56 |
| Mike Venafro* | Col | mr | 32 | .543 | 11 | .273 | 5 | .313 | 5 | .313 | 1.0 | 2.3 | 2.05 | 2.58 |
| Jose Veras | NYA | mr | 25 | .558 | 84 | .202 | 38 | .352 | 38 | .352 | 7.2 | 2.4 | 2.20 | 2.55 |
| Justin Verlander | Det | sp | 23 | .764 | 578 | .292 | 367 | .469 | 371 | .474 | 101.7 | 5.1 | 4.64 | 4.71 |
| Carlos Villanueva | Mil | sp | 22 | .811 | 110 | .245 | 84 | .528 | 86 | .541 | 22.8 | 5.4 | 4.86 | 4.29 |
| Oscar Villarreal | Atl | mr | 24 | .804 | 381 | .260 | 254 | .501 | 260 | .513 | 68.9 | 5.1 | 4.63 | 4.34 |
| Ron Villone* | NYA | mr | 36 | .693 | 203 | .256 | 150 | .446 | 152 | .452 | 36.8 | 4.3 | 3.82 | 3.36 |
| Luis Vizcaino | Ari | mr | 31 | .734 | 218 | .234 | 174 | .475 | 179 | .489 | 41.3 | 4.1 | 3.81 | 3.64 |
| Ryan Vogelsong | Pit | mr | 28 | .828 | 191 | .361 | 126 | .462 | 133 | .487 | 41.0 | 6.5 | 5.89 | 6.37 |
| Edinson Volquez | Tex | sp | 22 | .900 | 133 | .338 | 88 | .533 | 90 | .545 | 29.6 | 7.5 | 6.66 | 6.47 |
| Doug Waechter | Tam | sp | 25 | .734 | 213 | .324 | 105 | .410 | 108 | .422 | 31.9 | 4.9 | 4.49 | 4.55 |
| Billy Wagner* | NYN | cl | 34 | .635 | 204 | .363 | 141 | .376 | 143 | .381 | 34.9 | 3.5 | 3.18 | 3.27 |
| Ryan Wagner | Was | mr | 23 | .996 | 119 | .361 | 100 | .599 | 102 | .611 | 36.3 | 10.0 | 9.09 | 9.68 |
| Adam Wainwright | StL | mr | 24 | .678 | 236 | .297 | 142 | .397 | 148 | .413 | 36.7 | 3.9 | 3.47 | 3.23 |
| Tim Wakefield | Bos | sp | 39 | .781 | 398 | .296 | 263 | .465 | 277 | .490 | 79.4 | 5.7 | 5.12 | 5.21 |
| Jamie Walker* | Det | mr | 34 | .639 | 173 | .214 | 93 | .406 | 95 | .415 | 18.3 | 2.7 | 2.51 | 2.29 |
| Pete Walker | Tor | mr | 37 | .952 | 155 | .368 | 134 | .585 | 137 | .598 | 45.0 | 8.4 | 7.54 | 7.10 |
| Tyler Walker |   | mr | 30 | .485 | 88 | .227 | 38 | .297 | 38 | .297 | 6.7 | 1.8 | 1.71 | 1.63 |
| Les Walrond* | ChN | mr | 29 | .986 | 56 | .393 | 60 | .594 | 61 | .604 | 20.1 | 8.5 | 7.89 | 8.01 |
| Chien-Ming Wang | NYA | sp | 26 | .662 | 798 | .276 | 358 | .386 | 362 | .390 | 86.9 | 3.5 | 3.15 | 3.16 |
| John Wasdin | Tex | sp | 33 | .550 | 112 | .223 | 45 | .331 | 46 | .338 | 9.4 | 2.5 | 2.29 | 2.05 |
| Jarrod Washburn* | Sea | sp | 31 | .766 | 581 | .258 | 370 | .479 | 377 | .488 | 94.7 | 4.6 | 4.21 | 4.09 |
| David Weathers | Cin | mr | 36 | .645 | 243 | .214 | 135 | .413 | 136 | .416 | 29.1 | 3.2 | 2.97 | 3.02 |
| Jeff Weaver |   | sp | 29 | .872 | 529 | .308 | 386 | .536 | 394 | .547 | 118.5 | 6.6 | 6.02 | 5.80 |
| Jered Weaver | LAA | sp | 23 | .663 | 338 | .234 | 217 | .431 | 218 | .433 | 51.2 | 3.7 | 3.36 | 2.91 |
| Brandon Webb | Ari | sp | 27 | .675 | 720 | .294 | 379 | .400 | 388 | .409 | 97.2 | 3.8 | 3.43 | 3.15 |
| Todd Wellemeyer |   | mr | 27 | .728 | 304 | .250 | 206 | .455 | 213 | .470 | 49.4 | 4.3 | 3.90 | 4.47 |
| David Wells* |   | sp | 43 | .692 | 259 | .301 | 131 | .402 | 136 | .417 | 34.1 | 3.9 | 3.47 | 3.35 |
| Kip Wells |   | sp | 29 | 1.055 | 120 | .375 | 100 | .613 | 106 | .650 | 34.9 | 9.5 | 8.73 | 9.46 |
| Jake Westbrook | Cle | sp | 28 | .720 | 692 | .319 | 356 | .412 | 361 | .417 | 95.7 | 4.2 | 3.85 | 4.33 |
| Dan Wheeler | Hou | mr | 28 | .696 | 210 | .286 | 140 | .433 | 143 | .443 | 36.1 | 4.3 | 3.87 | 3.43 |
| Rick White |   | mr | 37 | .896 | 267 | .307 | 205 | .557 | 209 | .568 | 65.7 | 7.5 | 6.85 | 6.52 |
| Bob Wickman |   | cl | 37 | .698 | 211 | .336 | 118 | .401 | 121 | .412 | 32.0 | 4.2 | 3.90 | 3.82 |
| Dave Williams* |   | sp | 27 | .741 | 248 | .266 | 143 | .450 | 146 | .459 | 37.1 | 4.5 | 4.10 | 4.60 |
| Jerome Williams | ChN | mr | 24 | .929 | 40 | .425 | 26 | .491 | 27 | .509 | 9.6 | 8.9 | 8.30 | 10.54 |
| Todd Williams | Bal | mr | 35 | .922 | 306 | .350 | 208 | .553 | 209 | .556 | 65.3 | 7.1 | 6.35 | 6.96 |
| Woody Williams | SD | sp | 39 | .791 | 475 | .288 | 281 | .480 | 286 | .489 | 82.3 | 5.4 | 4.90 | 4.12 |
| Scott Williamson |   | mr | 30 | .822 | 150 | .353 | 122 | .496 | 124 | .504 | 36.9 | 6.3 | 5.79 | 6.01 |
| Dontrelle Willis* | Flo | sp | 24 | .748 | 669 | .296 | 421 | .434 | 444 | .457 | 116.9 | 4.7 | 4.33 | 4.67 |
| Brian Wilson | SF | mr | 24 | .836 | 139 | .345 | 103 | .505 | 103 | .505 | 32.5 | 6.9 | 6.12 | 6.36 |
| C.J. Wilson* | Tex | mr | 25 | .813 | 92 | .304 | 74 | .510 | 76 | .524 | 20.3 | 5.5 | 5.03 | 5.46 |
| Kris Wilson | NYA | mr | 29 | 1.750 | 10 | .500 | 14 | 1.167 | 14 | 1.167 | 8.5 | 45.7 | 41.16 | 39.46 |
| Jason Windsor | Oak | sp | 23 | 1.204 | 33 | .485 | 32 | .696 | 32 | .696 | 13.2 | 15.5 | 13.33 | 14.94 |
| Joe Winkelsas | Mil | mr | 32 | 1.185 | 42 | .381 | 44 | .733 | 44 | .733 | 15.5 | 11.9 | 10.16 | 11.49 |
| Matt Wise | Mil | mr | 30 | .712 | 171 | .263 | 94 | .422 | 100 | .448 | 25.5 | 4.3 | 4.05 | 3.84 |
| Jay Witasick | Oak | mr | 33 | 1.186 | 55 | .436 | 74 | .733 | 74 | .733 | 29.2 | 15.5 | 13.93 | 15.11 |
| Randy Wolf* | Phi | sp | 29 | .945 | 141 | .355 | 120 | .580 | 121 | .585 | 41.8 | 8.9 | 8.05 | 7.73 |
| Kerry Wood | ChN | sp | 29 | 1.072 | 52 | .288 | 60 | .723 | 61 | .735 | 19.9 | 9.9 | 8.94 | 8.32 |
| Mike Wood | KC | mr | 26 | .901 | 333 | .330 | 226 | .533 | 237 | .559 | 74.0 | 7.3 | 6.66 | 6.74 |
| Jake Woods* | Sea | mr | 24 | .696 | 392 | .281 | 234 | .425 | 238 | .432 | 56.2 | 3.9 | 3.51 | 3.47 |
| Tim Worrell | SF | cl | 38 | .703 | 73 | .260 | 42 | .429 | 43 | .439 | 10.8 | 4.2 | 3.80 | 3.85 |
| Jamey Wright | SF | sp | 31 | .782 | 446 | .296 | 277 | .472 | 282 | .480 | 73.5 | 4.8 | 4.34 | 4.69 |
| Jaret Wright | NYA | sp | 30 | .778 | 474 | .312 | 297 | .472 | 300 | .477 | 82.3 | 5.3 | 4.77 | 5.03 |
| Michael Wuertz | ChN | mr | 27 | .473 | 55 | .182 | 27 | .293 | 29 | .315 | 5.2 | 2.0 | 1.85 | 1.45 |
| Esteban Yan |   | mr | 31 | .812 | 141 | .241 | 110 | .516 | 112 | .526 | 28.8 | 5.4 | 4.82 | 5.02 |
| Tyler Yates | Atl | mr | 28 | .793 | 110 | .309 | 107 | .512 | 108 | .517 | 28.1 | 5.3 | 4.72 | 4.41 |
| Shane Youman* | Pit | sp | 26 | .630 | 57 | .158 | 30 | .417 | 30 | .417 | 5.5 | 2.6 | 2.46 | 2.45 |
| Chris Young | SD | sp | 27 | .644 | 468 | .233 | 309 | .418 | 312 | .422 | 71.1 | 3.5 | 3.17 | 2.83 |
| Carlos Zambrano | ChN | sp | 25 | .693 | 545 | .250 | 406 | .449 | 412 | .456 | 97.1 | 4.1 | 3.70 | 3.37 |
| Victor Zambrano | NYN | sp | 30 | .673 | 68 | .279 | 45 | .413 | 46 | .422 | 10.9 | 4.1 | 3.80 | 4.37 |
| Barry Zito* | Oak | sp | 28 | .690 | 636 | .267 | 384 | .425 | 392 | .434 | 94.4 | 3.9 | 3.54 | 3.59 |
| Joel Zumaya | Det | mr | 21 | .727 | 185 | .319 | 138 | .448 | 140 | .455 | 37.4 | 4.7 | 4.21 | 4.15 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | PCH/G | STR% |
| David Aardsma | ChN | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 24.4 | .596 |
| Winston Abreu | Bal | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 37.3 | .557 |
| Jeremy Accardo |   | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 23.2 | .630 |
| Jon Adkins | SD | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 23.5 | .621 |
| Jeremy Affeldt* |   | mr | 27 | 9 | 0 | .000 | 0 | 5 | .556 | 48 | 5.3 | 18 | 8 | .444 | 33.7 | .593 |
| Matt Albers | Hou | sp | 23 | 2 | 0 | .000 | 0 | 2 | 1.000 | 1 | 0.5 | 1 | 0 | .000 | 92.5 | .611 |
| Antonio Alfonseca | Tex | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 19.7 | .587 |
| Steve Andrade | KC | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 19.0 | .421 |
| Greg Aquino | Ari | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 9 | .310 | 32.1 | .594 |
| Tony Armas | Was | sp | 28 | 30 | 0 | .000 | 0 | 13 | .433 | 163 | 5.4 | 27 | 9 | .333 | 78.2 | .614 |
| Bronson Arroyo | Cin | sp | 29 | 35 | 6 | .171 | 0 | 22 | .629 | 189 | 5.4 | 21 | 7 | .333 | 97.8 | .627 |
| Miguel Asencio | Col | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 1 | 1 | 1.000 | 88.0 | .545 |
| Ezequiel Astacio | Hou | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 28.0 | .625 |
| Pedro Astacio | Was | sp | 36 | 17 | 0 | .000 | 0 | 7 | .412 | 94 | 5.5 | 15 | 5 | .333 | 79.6 | .621 |
| Brandon Backe | Hou | sp | 28 | 8 | 0 | .000 | 0 | 2 | .250 | 28 | 3.5 | 5 | 3 | .600 | 81.3 | .597 |
| Cha Seung Baek | Sea | sp | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 36 | 6.0 | 3 | 0 | .000 | 89.2 | .587 |
| Danys Baez |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 18.4 | .640 |
| Jeff Bajenaru | Ari | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 26.5 | .528 |
| Scott Baker | Min | sp | 24 | 16 | 0 | .000 | 0 | 7 | .438 | 67 | 4.2 | 15 | 2 | .133 | 75.4 | .666 |
| Brian Bannister | NYN | sp | 25 | 6 | 0 | .000 | 0 | 0 | .000 | 26 | 4.3 | 6 | 3 | .500 | 85.2 | .571 |
| Kevin Barry | Atl | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 6 | 4 | .667 | 26.1 | .579 |
| Miguel Batista | Ari | sp | 35 | 33 | 1 | .030 | 0 | 9 | .273 | 154 | 4.7 | 27 | 5 | .185 | 76.9 | .595 |
| Rick Bauer | Tex | mr | 29 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 16 | 3 | .188 | 24.7 | .611 |
| Denny Bautista |   | mr | 23 | 8 | 0 | .000 | 0 | 2 | .250 | 39 | 4.9 | 2 | 1 | .500 | 68.0 | .609 |
| Jonah Bayliss | Pit | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 27.6 | .569 |
| T.J. Beam | NYA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 20.3 | .596 |
| Josh Beckett | Bos | sp | 26 | 33 | 2 | .061 | 1 | 20 | .606 | 169 | 5.1 | 19 | 8 | .421 | 93.6 | .619 |
| Erik Bedard* | Bal | sp | 27 | 33 | 1 | .030 | 0 | 15 | .455 | 179 | 5.4 | 28 | 10 | .357 | 94.0 | .614 |
| Joe Beimel* | LAN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 13 | .325 | 16.9 | .579 |
| Matt Belisle | Cin | mr | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 7 | 3.5 | 13 | 1 | .077 | 26.9 | .600 |
| Heath Bell | NYN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 | 25.3 | .632 |
| Armando Benitez | SF | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 7 | .292 | 19.5 | .600 |
| Joaquin Benoit | Tex | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 28.8 | .600 |
| Kris Benson | Bal | sp | 31 | 30 | 1 | .033 | 0 | 11 | .367 | 127 | 4.2 | 19 | 11 | .579 | 91.9 | .611 |
| Jason Bergmann | Was | mr | 24 | 6 | 0 | .000 | 0 | 1 | .167 | 29 | 4.8 | 13 | 6 | .462 | 38.3 | .623 |
| Adam Bernero |   | sp | 29 | 3 | 0 | .000 | 0 | 2 | .667 | 14 | 4.7 | 2 | 0 | .000 | 74.7 | .688 |
| Rafael Betancourt | Cle | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 | 18.9 | .709 |
| Chad Billingsley | LAN | sp | 21 | 16 | 0 | .000 | 0 | 9 | .563 | 64 | 4.0 | 12 | 3 | .250 | 96.8 | .566 |
| Kurt Birkins* | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 20.8 | .573 |
| Joe Blanton | Oak | sp | 25 | 31 | 3 | .097 | 2 | 20 | .645 | 146 | 4.7 | 29 | 9 | .310 | 93.8 | .639 |
| Jeremy Bonderman | Det | sp | 23 | 34 | 5 | .147 | 2 | 19 | .559 | 183 | 5.4 | 29 | 10 | .345 | 96.5 | .642 |
| Boof Bonser | Min | sp | 24 | 18 | 0 | .000 | 0 | 9 | .500 | 74 | 4.1 | 8 | 3 | .375 | 82.1 | .639 |
| Chris Booker |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 19.2 | .667 |
| Chris Bootcheck | LAA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 | 60.5 | .526 |
| Dave Borkowski | Hou | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 | 30.0 | .655 |
| Joe Borowski | Flo | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 19.5 | .626 |
| Micah Bowie* | Was | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 23.5 | .583 |
| Chad Bradford | NYN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 | 23.2 | .676 |
| Ryan Braun | KC | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 28.6 | .643 |
| Bill Bray* |   | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 12 | .429 | 18.2 | .602 |
| Dewon Brazelton | SD | mr | 26 | 2 | 0 | .000 | 0 | 2 | 1.000 | 15 | 7.5 | 5 | 3 | .600 | 52.2 | .605 |
| Craig Breslow* | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 20.3 | .557 |
| Eude Brito* | Phi | mr | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 15 | 7.5 | 2 | 0 | .000 | 57.5 | .530 |
| Chris Britton | Bal | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 21.5 | .640 |
| Doug Brocail | SD | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 20.9 | .626 |
| Jim Brower |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 7 | .700 | 31.4 | .535 |
| Andrew Brown | Cle | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 14.9 | .575 |
| Jonathan Broxton | LAN | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 6 | .273 | 19.5 | .624 |
| Brian Bruney | NYA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 29.7 | .505 |
| Taylor Buchholz | Hou | sp | 24 | 19 | 0 | .000 | 0 | 8 | .421 | 66 | 3.5 | 15 | 6 | .400 | 78.8 | .629 |
| Mark Buehrle* | ChA | sp | 27 | 32 | 0 | .000 | 0 | 12 | .375 | 138 | 4.3 | 27 | 6 | .222 | 86.1 | .636 |
| Ambiorix Burgos | KC | cl | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 37 | 15 | .405 | 22.0 | .594 |
| A.J. Burnett | Tor | sp | 29 | 21 | 0 | .000 | 0 | 8 | .381 | 115 | 5.5 | 25 | 5 | .200 | 88.2 | .626 |
| Mike Burns |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 24.0 | .610 |
| Brian Burres* | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 11.3 | .622 |
| Dave Bush | Mil | sp | 26 | 32 | 5 | .156 | 1 | 16 | .500 | 158 | 4.9 | 18 | 6 | .333 | 98.7 | .665 |
| Paul Byrd | Cle | sp | 35 | 31 | 3 | .097 | 1 | 20 | .645 | 195 | 6.3 | 24 | 8 | .333 | 87.0 | .670 |
| Tim Byrdak* | Bal | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 26.0 | .474 |
| Daniel Cabrera | Bal | sp | 25 | 26 | 1 | .038 | 1 | 13 | .500 | 137 | 5.3 | 22 | 12 | .545 | 94.6 | .565 |
| Fernando Cabrera | Cle | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 | 26.7 | .575 |
| Matt Cain | SF | sp | 21 | 31 | 1 | .032 | 1 | 21 | .677 | 131 | 4.2 | 19 | 8 | .421 | 92.8 | .611 |
| Kiko Calero | Oak | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 10 | .286 | 17.9 | .601 |
| Shawn Camp | Tam | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 48 | 28 | .583 | 25.6 | .637 |
| Jose Capellan | Mil | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 26.1 | .613 |
| Matt Capps | Pit | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 7 | .368 | 20.4 | .691 |
| Chris Capuano* | Mil | sp | 27 | 34 | 1 | .029 | 0 | 19 | .559 | 167 | 4.9 | 13 | 4 | .308 | 96.9 | .660 |
| Fausto Carmona | Cle | mr | 22 | 7 | 0 | .000 | 0 | 0 | .000 | 35 | 5.0 | 19 | 4 | .211 | 32.6 | .625 |
| Chris Carpenter | StL | sp | 31 | 32 | 6 | .188 | 4 | 17 | .531 | 162 | 5.1 | 15 | 7 | .467 | 96.0 | .664 |
| Giovanni Carrara | LAN | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 28.3 | .651 |
| Hector Carrasco | LAA | mr | 36 | 3 | 1 | .333 | 0 | 1 | .333 | 13 | 4.3 | 23 | 6 | .261 | 33.1 | .625 |
| Lance Carter | LAN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 12.0 | .604 |
| Santiago Casilla | Oak | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .600 |
| Scott Cassidy | SD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 18.2 | .633 |
| Fabio Castro* |   | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 7 | .778 | 25.8 | .585 |
| Gustavo Chacin* | Tor | sp | 25 | 17 | 0 | .000 | 0 | 4 | .235 | 75 | 4.4 | 19 | 6 | .316 | 80.4 | .597 |
| Shawn Chacon |   | sp | 28 | 20 | 0 | .000 | 0 | 2 | .100 | 81 | 4.1 | 20 | 11 | .550 | 61.9 | .576 |
| Bruce Chen* | Bal | mr | 29 | 12 | 0 | .000 | 0 | 3 | .250 | 57 | 4.8 | 30 | 10 | .333 | 36.5 | .618 |
| Jason Childers | Tam | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 40.0 | .606 |
| Randy Choate* | Ari | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 15.4 | .676 |
| Vinnie Chulk |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 21.4 | .615 |
| Brandon Claussen* | Cin | sp | 27 | 14 | 0 | .000 | 0 | 3 | .214 | 70 | 5.0 | 12 | 4 | .333 | 79.5 | .588 |
| Roger Clemens | Hou | sp | 43 | 19 | 1 | .053 | 1 | 14 | .737 | 92 | 4.8 | 4 | 0 | .000 | 95.2 | .648 |
| Matt Clement | Bos | sp | 31 | 12 | 0 | .000 | 0 | 4 | .333 | 69 | 5.8 | 16 | 9 | .563 | 90.8 | .562 |
| Todd Coffey | Cin | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 9 | .265 | 17.9 | .612 |
| Bartolo Colon | LAA | sp | 33 | 10 | 0 | .000 | 0 | 7 | .700 | 55 | 5.5 | 9 | 2 | .222 | 87.9 | .659 |
| Roman Colon | Det | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 8 | 0 | .000 | 35.1 | .632 |
| Clay Condrey | Phi | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 24.9 | .637 |
| Jose Contreras | ChA | sp | 34 | 30 | 0 | .000 | 0 | 14 | .467 | 144 | 4.8 | 29 | 5 | .172 | 90.2 | .642 |
| Aaron Cook | Col | sp | 27 | 32 | 2 | .063 | 2 | 16 | .500 | 155 | 4.8 | 22 | 7 | .318 | 81.8 | .645 |
| Roy Corcoran | Was | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.2 | .653 |
| Tim Corcoran | Tam | sp | 28 | 16 | 0 | .000 | 0 | 7 | .438 | 66 | 4.1 | 19 | 10 | .526 | 64.2 | .580 |
| Chad Cordero | Was | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 19.0 | .645 |
| Francisco Cordero |   | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 9 | .310 | 18.9 | .623 |
| Bryan Corey |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 31.6 | .629 |
| Lance Cormier | Atl | mr | 25 | 9 | 0 | .000 | 0 | 3 | .333 | 58 | 6.4 | 30 | 16 | .533 | 38.8 | .589 |
| Rheal Cormier* |   | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 9 | .391 | 17.8 | .598 |
| Manuel Corpas | Col | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 23.7 | .688 |
| Kevin Correia | SF | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 26.1 | .636 |
| David Cortes | Col | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 21.3 | .652 |
| Neal Cotts* | ChA | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 11 | .275 | 20.0 | .599 |
| Jesse Crain | Min | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 18.2 | .665 |
| Francisco Cruceta | Sea | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 0 | 0 | .000 | 74.0 | .622 |
| Juan Cruz | Ari | mr | 27 | 15 | 0 | .000 | 0 | 9 | .600 | 70 | 4.7 | 21 | 9 | .429 | 52.1 | .591 |
| Casey Daigle | Ari | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 18.0 | .611 |
| Kyle Davies | Atl | sp | 22 | 14 | 0 | .000 | 0 | 2 | .143 | 95 | 6.8 | 12 | 2 | .167 | 67.4 | .591 |
| Doug Davis* | Mil | sp | 30 | 34 | 1 | .029 | 0 | 18 | .529 | 143 | 4.2 | 24 | 12 | .500 | 103.2 | .594 |
| Jason Davis | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 9 | .643 | 31.9 | .657 |
| Zach Day |   | sp | 28 | 8 | 0 | .000 | 0 | 3 | .375 | 27 | 3.4 | 8 | 1 | .125 | 71.8 | .599 |
| Jorge De La Rosa* |   | mr | 25 | 13 | 0 | .000 | 0 | 1 | .077 | 74 | 5.7 | 17 | 5 | .294 | 65.3 | .554 |
| Manny Delcarmen | Bos | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 25.9 | .640 |
| Chris Demaria | Mil | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 30.2 | .597 |
| Ryan Dempster | ChN | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 19.6 | .596 |
| Elmer Dessens |   | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 20.6 | .664 |
| Joey Devine | Atl | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 21.8 | .500 |
| R.A. Dickey | Tex | sp | 31 | 1 | 0 | .000 | 0 | 1 | 1.000 | 0 | 0.0 | 0 | 0 | .000 | 87.0 | .701 |
| Lenny DiNardo* | Bos | mr | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 16 | 2.7 | 8 | 1 | .125 | 52.3 | .585 |
| Scott Dohmann |   | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 22.9 | .559 |
| Brendan Donnelly | LAA | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 19.7 | .618 |
| Octavio Dotel | NYA | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 33.3 | .530 |
| Scott Downs* | Tor | mr | 30 | 5 | 0 | .000 | 0 | 4 | .800 | 34 | 6.8 | 23 | 7 | .304 | 32.0 | .600 |
| Ryan Drese | Was | sp | 30 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 4 | 4 | 1.000 | 60.0 | .483 |
| Justin Duchscherer | Oak | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 20.0 | .646 |
| Brandon Duckworth | KC | sp | 30 | 8 | 0 | .000 | 0 | 2 | .250 | 37 | 4.6 | 5 | 5 | 1.000 | 67.8 | .620 |
| Zach Duke* | Pit | sp | 23 | 34 | 2 | .059 | 1 | 19 | .559 | 172 | 5.1 | 26 | 8 | .308 | 84.1 | .627 |
| Scott Dunn | Tam | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 30.0 | .583 |
| Chad Durbin | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 17.7 | .613 |
| Adam Eaton | Tex | sp | 28 | 13 | 0 | .000 | 0 | 5 | .385 | 52 | 4.0 | 15 | 7 | .467 | 79.5 | .618 |
| Joey Eischen* | Was | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 23.8 | .538 |
| Scott Elarton | KC | sp | 30 | 20 | 0 | .000 | 0 | 7 | .350 | 116 | 5.8 | 17 | 3 | .176 | 81.8 | .603 |
| Alan Embree* | SD | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 11 | .324 | 14.4 | .630 |
| Scott Erickson | NYA | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 11.0 | .636 |
| Kelvim Escobar | LAA | sp | 30 | 30 | 2 | .067 | 1 | 19 | .633 | 140 | 4.7 | 28 | 12 | .429 | 92.9 | .645 |
| Shawn Estes* | SD | sp | 33 | 1 | 1 | 1.000 | 1 | 1 | 1.000 | 16 | 16.0 | 0 | 0 | .000 | 103.0 | .680 |
| Seth Etherton | KC | sp | 29 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 2 | 1 | .500 | 69.0 | .536 |
| Dana Eveland* | Mil | sp | 22 | 5 | 0 | .000 | 0 | 2 | .400 | 18 | 3.6 | 6 | 4 | .667 | 100.8 | .597 |
| Scott Eyre* | ChN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 19.6 | .617 |
| Willie Eyre | Min | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 | 27.9 | .607 |
| Brian Falkenborg | StL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 17.4 | .586 |
| Kyle Farnsworth | NYA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 10 | .278 | 18.7 | .612 |
| Jeff Fassero* | SF | mr | 43 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 9 | 1 | .111 | 28.3 | .580 |
| Ryan Feierabend* | Sea | sp | 20 | 2 | 0 | .000 | 0 | 1 | .500 | 20 | 10.0 | 0 | 0 | .000 | 102.0 | .578 |
| Scott Feldman | Tex | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 9 | .429 | 19.7 | .641 |
| Pedro Feliciano* | NYN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 17 | .370 | 16.7 | .591 |
| Nate Field | Col | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 17.0 | .571 |
| Randy Flores* | StL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 14.4 | .577 |
| Ron Flores* | Oak | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 25.0 | .641 |
| Gavin Floyd | Phi | sp | 23 | 11 | 0 | .000 | 0 | 2 | .182 | 78 | 7.1 | 8 | 5 | .625 | 67.9 | .565 |
| Josh Fogg | Col | sp | 29 | 31 | 1 | .032 | 0 | 12 | .387 | 128 | 4.1 | 26 | 10 | .385 | 85.1 | .631 |
| Casey Fossum* | Tam | sp | 28 | 25 | 0 | .000 | 0 | 11 | .440 | 122 | 4.9 | 24 | 10 | .417 | 83.8 | .609 |
| Keith Foulke | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 19.0 | .658 |
| Jeff Francis* | Col | sp | 25 | 32 | 2 | .063 | 2 | 18 | .563 | 154 | 4.8 | 12 | 5 | .417 | 87.2 | .619 |
| Frank Francisco | Tex | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 29.0 | .644 |
| Ryan Franklin |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 10 | .323 | 17.6 | .645 |
| Wayne Franklin* | Atl | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 18.3 | .452 |
| Jason Frasor | Tor | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 | 21.9 | .625 |
| Emiliano Fruto | Sea | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 40.8 | .564 |
| Brian Fuentes* | Col | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 19.1 | .595 |
| Aaron Fultz* | Phi | mr | 32 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 27 | 4 | .148 | 22.5 | .608 |
| Kason Gabbard* | Bos | sp | 24 | 4 | 1 | .250 | 1 | 3 | .750 | 17 | 4.3 | 0 | 0 | .000 | 100.5 | .535 |
| Mike Gallo* | Hou | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 21.4 | .572 |
| Freddy Garcia | ChA | sp | 30 | 33 | 2 | .061 | 1 | 17 | .515 | 153 | 4.6 | 11 | 4 | .364 | 93.7 | .661 |
| Jose Garcia | Flo | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 36.3 | .596 |
| Jon Garland | ChA | sp | 26 | 32 | 4 | .125 | 2 | 15 | .469 | 175 | 5.5 | 29 | 12 | .414 | 80.3 | .667 |
| Matt Garza | Min | sp | 22 | 9 | 0 | .000 | 0 | 3 | .333 | 37 | 4.1 | 8 | 1 | .125 | 85.6 | .606 |
| Chad Gaudin | Oak | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 8 | .364 | 27.3 | .553 |
| Geoff Geary | Phi | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 | 21.7 | .664 |
| Franklyn German | Flo | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 20.5 | .553 |
| Justin Germano | Cin | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 0 | 0 | .000 | 64.0 | .672 |
| Tom Glavine* | NYN | sp | 40 | 32 | 0 | .000 | 0 | 12 | .375 | 159 | 5.0 | 28 | 9 | .321 | 81.9 | .639 |
| Jimmy Gobble* | KC | mr | 24 | 6 | 0 | .000 | 0 | 1 | .167 | 30 | 5.0 | 29 | 12 | .414 | 30.1 | .611 |
| Edgar Gonzalez | Ari | mr | 23 | 5 | 1 | .200 | 0 | 4 | .800 | 26 | 5.2 | 3 | 1 | .333 | 43.6 | .665 |
| Enrique Gonzalez | Ari | sp | 23 | 18 | 1 | .056 | 1 | 11 | .611 | 95 | 5.3 | 6 | 3 | .500 | 84.6 | .640 |
| Geremi Gonzalez |   | mr | 31 | 4 | 0 | .000 | 0 | 0 | .000 | 13 | 3.3 | 16 | 6 | .375 | 35.2 | .632 |
| Mike Gonzalez* | Pit | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 9 | .429 | 21.6 | .591 |
| Tom Gordon | Phi | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 19.4 | .610 |
| Tom Gorzelanny* | Pit | sp | 23 | 11 | 0 | .000 | 0 | 6 | .545 | 38 | 3.5 | 6 | 4 | .667 | 97.7 | .593 |
| Mike Gosling* | Cin | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 13.0 | .615 |
| John Grabow* | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 23.6 | .614 |
| Danny Graves | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 28.5 | .561 |
| Sean Green | Sea | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 27.0 | .575 |
| Kevin Gregg | LAA | mr | 28 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 16 | 8 | .500 | 35.9 | .639 |
| Jason Grilli | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 16 | .390 | 20.7 | .600 |
| Jason Grimsley | Ari | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 21.8 | .615 |
| Kevin Gryboski | Was | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 37.3 | .643 |
| Eddie Guardado* |   | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 1 | .059 | 15.6 | .632 |
| Matt Guerrier | Min | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 21 | 7 | .333 | 36.4 | .616 |
| Jeremy Guthrie | Cle | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 11 | 11.0 | 5 | 5 | 1.000 | 39.1 | .548 |
| Angel Guzman | ChN | sp | 24 | 10 | 0 | .000 | 0 | 0 | .000 | 54 | 5.4 | 10 | 5 | .500 | 53.3 | .593 |
| Charlie Haeger | ChA | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 6 | 1 | .167 | 57.3 | .546 |
| John Halama* | Bal | mr | 34 | 1 | 0 | .000 | 0 | 1 | 1.000 | 5 | 5.0 | 6 | 4 | .667 | 39.5 | .627 |
| Roy Halladay | Tor | sp | 29 | 32 | 5 | .156 | 2 | 24 | .750 | 153 | 4.8 | 11 | 3 | .273 | 93.3 | .673 |
| Brad Halsey* | Oak | mr | 25 | 7 | 0 | .000 | 0 | 3 | .429 | 43 | 6.1 | 19 | 7 | .368 | 39.7 | .601 |
| Cole Hamels* | Phi | sp | 22 | 23 | 1 | .043 | 0 | 12 | .522 | 121 | 5.3 | 17 | 7 | .412 | 96.8 | .612 |
| Jason Hammel | Tam | sp | 23 | 9 | 0 | .000 | 0 | 3 | .333 | 36 | 4.0 | 11 | 5 | .455 | 70.6 | .600 |
| Chris Hammond* | Cin | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 23.0 | .634 |
| Justin Hampson* | Col | mr | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 6 | 6.0 | 1 | 1 | 1.000 | 100.0 | .640 |
| Tim Hamulack* | LAN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 20.2 | .595 |
| Josh Hancock | StL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 23.6 | .621 |
| Devern Hansack | Bos | sp | 28 | 2 | 0 | .000 | 0 | 1 | .500 | 16 | 8.0 | 0 | 0 | .000 | 85.0 | .594 |
| Craig Hansen | Bos | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 24.1 | .651 |
| Aaron Harang | Cin | sp | 28 | 35 | 3 | .086 | 3 | 13 | .371 | 162 | 4.6 | 26 | 11 | .423 | 91.7 | .663 |
| Rich Harden | Oak | sp | 24 | 9 | 0 | .000 | 0 | 6 | .667 | 58 | 6.4 | 5 | 3 | .600 | 97.1 | .573 |
| Dan Haren | Oak | sp | 25 | 34 | 0 | .000 | 0 | 19 | .559 | 155 | 4.6 | 16 | 8 | .500 | 88.9 | .663 |
| Travis Harper | Tam | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 8 | .571 | 25.3 | .632 |
| Chad Harville | Tam | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 24.4 | .591 |
| LaTroy Hawkins | Bal | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 7 | .219 | 20.0 | .650 |
| Aaron Heilman | NYN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 13 | .333 | 16.9 | .629 |
| Rick Helling | Mil | mr | 35 | 2 | 0 | .000 | 0 | 2 | 1.000 | 8 | 4.0 | 2 | 0 | .000 | 39.6 | .631 |
| Ben Hendrickson | Mil | sp | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 6 | 2.0 | 4 | 3 | .750 | 75.0 | .529 |
| Mark Hendrickson* |   | sp | 32 | 25 | 2 | .080 | 0 | 14 | .560 | 157 | 6.3 | 25 | 8 | .320 | 95.3 | .598 |
| Sean Henn* | NYA | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 0 | 0 | .000 | 80.0 | .575 |
| Brad Hennessey | SF | mr | 26 | 12 | 0 | .000 | 0 | 3 | .250 | 58 | 4.8 | 15 | 6 | .400 | 49.1 | .598 |
| Clay Hensley | SD | sp | 26 | 29 | 0 | .000 | 0 | 12 | .414 | 164 | 5.7 | 28 | 14 | .500 | 75.7 | .601 |
| Matt Herges | Flo | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 8 | .333 | 23.0 | .618 |
| Dustin Hermanson | ChA | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 29.5 | .559 |
| Felix Hernandez | Sea | sp | 20 | 31 | 2 | .065 | 1 | 18 | .581 | 121 | 3.9 | 24 | 10 | .417 | 104.0 | .632 |
| Livan Hernandez |   | sp | 31 | 34 | 0 | .000 | 0 | 15 | .441 | 166 | 4.9 | 30 | 12 | .400 | 84.5 | .620 |
| Orlando Hernandez |   | sp | 36 | 29 | 1 | .034 | 0 | 13 | .448 | 181 | 6.2 | 17 | 8 | .471 | 93.6 | .618 |
| Roberto Hernandez |   | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 9 | .321 | 21.7 | .620 |
| Runelvys Hernandez | KC | sp | 28 | 21 | 0 | .000 | 0 | 5 | .238 | 86 | 4.1 | 24 | 13 | .542 | 84.7 | .596 |
| Rich Hill* | ChN | sp | 26 | 16 | 0 | .000 | 0 | 11 | .688 | 108 | 6.8 | 6 | 1 | .167 | 101.5 | .620 |
| Shawn Hill | Was | sp | 25 | 6 | 0 | .000 | 0 | 3 | .500 | 21 | 3.5 | 5 | 1 | .200 | 95.3 | .589 |
| Jason Hirsh | Hou | sp | 24 | 9 | 1 | .111 | 1 | 2 | .222 | 57 | 6.3 | 3 | 1 | .333 | 75.1 | .618 |
| James Hoey | Bal | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 28.7 | .540 |
| Trevor Hoffman | SD | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 16.3 | .654 |
| J.P. Howell* | Tam | sp | 23 | 8 | 0 | .000 | 0 | 2 | .250 | 43 | 5.4 | 6 | 6 | 1.000 | 83.3 | .616 |
| Bob Howry | ChN | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 8 | .276 | 18.7 | .654 |
| Jon Huber | Sea | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 23.9 | .609 |
| Luke Hudson | KC | sp | 29 | 15 | 0 | .000 | 0 | 5 | .333 | 57 | 3.8 | 23 | 13 | .565 | 54.8 | .616 |
| Tim Hudson | Atl | sp | 30 | 35 | 2 | .057 | 2 | 17 | .486 | 157 | 4.5 | 25 | 14 | .560 | 92.5 | .628 |
| Travis Hughes | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 31.1 | .576 |
| Jason Isringhausen | StL | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 10 | .345 | 21.8 | .546 |
| Edwin Jackson | Tam | mr | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 12 | 2 | .167 | 31.3 | .573 |
| Zach Jackson* | Mil | sp | 23 | 7 | 0 | .000 | 0 | 1 | .143 | 35 | 5.0 | 7 | 3 | .429 | 76.1 | .629 |
| Chuck James* | Atl | sp | 24 | 18 | 0 | .000 | 0 | 3 | .167 | 83 | 4.6 | 19 | 3 | .158 | 62.0 | .583 |
| Casey Janssen | Tor | sp | 24 | 17 | 2 | .118 | 0 | 8 | .471 | 103 | 6.1 | 12 | 6 | .500 | 83.2 | .649 |
| Kevin Jarvis |   | mr | 36 | 4 | 0 | .000 | 0 | 2 | .500 | 10 | 2.5 | 4 | 1 | .250 | 48.3 | .637 |
| Bobby Jenks | ChA | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 17.8 | .645 |
| Jason Jennings | Col | sp | 27 | 32 | 3 | .094 | 1 | 20 | .625 | 126 | 3.9 | 22 | 6 | .273 | 99.1 | .605 |
| Cesar Jimenez* | Sea | mr | 21 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 0 | 0 | .000 | 37.0 | .595 |
| Ubaldo Jimenez | Col | sp | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 0 | 0 | .000 | 108.0 | .602 |
| Jason Johnson |   | mr | 32 | 20 | 0 | .000 | 0 | 7 | .350 | 114 | 5.7 | 27 | 5 | .185 | 72.3 | .629 |
| Jim Johnson | Bal | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 3 | 1 | .333 | 45.0 | .489 |
| Josh Johnson | Flo | sp | 22 | 24 | 0 | .000 | 0 | 15 | .625 | 134 | 5.6 | 20 | 4 | .200 | 81.3 | .621 |
| Randy Johnson* | NYA | sp | 42 | 33 | 1 | .030 | 1 | 22 | .667 | 224 | 6.8 | 18 | 9 | .500 | 92.7 | .630 |
| Tyler Johnson* | StL | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 12 | .522 | 14.3 | .569 |
| Greg Jones | LAA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 10.3 | .634 |
| Todd Jones | Det | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 | 12.3 | .667 |
| Jorge Julio |   | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 20.5 | .590 |
| Steve Karsay | Oak | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 26.6 | .601 |
| Jeff Karstens | NYA | sp | 23 | 6 | 2 | .333 | 1 | 2 | .333 | 34 | 5.7 | 3 | 0 | .000 | 95.7 | .631 |
| Scott Kazmir* | Tam | sp | 22 | 24 | 0 | .000 | 0 | 10 | .417 | 104 | 4.3 | 25 | 20 | .800 | 97.8 | .606 |
| Randy Keisler* | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 22.3 | .572 |
| Joe Kennedy* | Oak | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 17.7 | .640 |
| Logan Kensing | Flo | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 10 | .385 | 19.3 | .590 |
| Bobby Keppel | KC | sp | 24 | 6 | 0 | .000 | 0 | 2 | .333 | 25 | 4.2 | 10 | 4 | .400 | 82.2 | .613 |
| Byung-Hyun Kim | Col | sp | 27 | 27 | 1 | .037 | 0 | 13 | .481 | 136 | 5.0 | 18 | 11 | .611 | 87.5 | .615 |
| Sun-Woo Kim |   | mr | 28 | 1 | 0 | .000 | 0 | 1 | 1.000 | 1 | 1.0 | 1 | 0 | .000 | 40.7 | .590 |
| Ray King* | Col | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 52 | 18 | .346 | 16.1 | .575 |
| Josh Kinney | StL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 24.4 | .620 |
| Steve Kline* | SF | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 57 | 16 | .281 | 14.8 | .590 |
| Dan Kolb | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 45 | 14 | .311 | 16.8 | .598 |
| Shane Komine | Oak | sp | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 1 | 0 | .000 | 72.0 | .563 |
| John Koronka* | Tex | sp | 25 | 23 | 0 | .000 | 0 | 10 | .435 | 109 | 4.7 | 16 | 4 | .250 | 79.6 | .631 |
| Hong-Chih Kuo* | LAN | mr | 24 | 5 | 0 | .000 | 0 | 4 | .800 | 22 | 4.4 | 12 | 5 | .417 | 38.9 | .620 |
| John Lackey | LAA | sp | 27 | 33 | 5 | .152 | 3 | 18 | .545 | 132 | 4.0 | 34 | 11 | .324 | 93.5 | .620 |
| Juan Lara* | Cle | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 10.8 | .558 |
| Brandon League | Tor | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 20.3 | .680 |
| Wilfredo Ledezma* | Det | mr | 25 | 7 | 0 | .000 | 0 | 1 | .143 | 34 | 4.9 | 12 | 4 | .333 | 36.5 | .631 |
| Cliff Lee* | Cle | sp | 27 | 33 | 1 | .030 | 1 | 15 | .455 | 142 | 4.3 | 30 | 14 | .467 | 86.3 | .636 |
| Justin Lehr | Mil | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 24.2 | .648 |
| Jon Lester* | Bos | sp | 22 | 15 | 0 | .000 | 0 | 6 | .400 | 85 | 5.7 | 15 | 5 | .333 | 87.2 | .589 |
| Colby Lewis | Det | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 31.0 | .548 |
| Brad Lidge | Hou | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 18.8 | .603 |
| Cory Lidle |   | sp | 34 | 30 | 0 | .000 | 0 | 12 | .400 | 170 | 5.7 | 24 | 8 | .333 | 85.2 | .615 |
| Jon Lieber | Phi | sp | 36 | 27 | 1 | .037 | 0 | 11 | .407 | 183 | 6.8 | 22 | 6 | .273 | 82.3 | .693 |
| Ted Lilly* | Tor | sp | 30 | 32 | 0 | .000 | 0 | 15 | .469 | 154 | 4.8 | 23 | 8 | .348 | 88.9 | .592 |
| Jose Lima | NYN | sp | 33 | 4 | 0 | .000 | 0 | 1 | .250 | 16 | 4.0 | 4 | 1 | .250 | 52.3 | .622 |
| Scott Linebrink | SD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 9 | .281 | 17.8 | .638 |
| Francisco Liriano* | Min | sp | 22 | 16 | 3 | .188 | 2 | 10 | .625 | 75 | 4.7 | 14 | 5 | .357 | 65.4 | .643 |
| Wes Littleton | Tex | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 24.1 | .597 |
| Esteban Loaiza | Oak | sp | 34 | 26 | 3 | .115 | 1 | 16 | .615 | 143 | 5.5 | 23 | 9 | .391 | 94.6 | .636 |
| Kameron Loe | Tex | sp | 24 | 15 | 0 | .000 | 0 | 7 | .467 | 51 | 3.4 | 13 | 6 | .462 | 80.9 | .635 |
| Adam Loewen* | Bal | sp | 22 | 19 | 1 | .053 | 0 | 8 | .421 | 98 | 5.2 | 21 | 7 | .333 | 101.9 | .570 |
| Boone Logan* | ChA | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 28.8 | .595 |
| Kyle Lohse |   | sp | 27 | 19 | 0 | .000 | 0 | 10 | .526 | 82 | 4.3 | 17 | 6 | .353 | 65.0 | .634 |
| Braden Looper | StL | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 56 | 18 | .321 | 16.9 | .645 |
| Javier Lopez* | Bos | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 19.0 | .584 |
| Rodrigo Lopez | Bal | sp | 30 | 29 | 1 | .034 | 0 | 12 | .414 | 137 | 4.7 | 26 | 13 | .500 | 81.3 | .629 |
| Derek Lowe | LAN | sp | 33 | 34 | 2 | .059 | 1 | 20 | .588 | 183 | 5.4 | 26 | 9 | .346 | 96.0 | .636 |
| Mark Lowe | Sea | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 37.8 | .596 |
| Noah Lowry* | SF | sp | 25 | 27 | 1 | .037 | 1 | 13 | .481 | 119 | 4.4 | 16 | 5 | .313 | 87.1 | .614 |
| Ruddy Lugo | Tam | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 15 | .455 | 21.8 | .596 |
| Brandon Lyon | Ari | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 17.4 | .658 |
| Mike MacDougal |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 21.2 | .636 |
| Greg Maddux |   | sp | 40 | 34 | 1 | .029 | 1 | 19 | .559 | 124 | 3.6 | 14 | 7 | .500 | 86.4 | .664 |
| Ryan Madson | Phi | mr | 25 | 17 | 0 | .000 | 0 | 4 | .235 | 127 | 7.5 | 31 | 10 | .323 | 44.4 | .637 |
| Ron Mahay* | Tex | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 5 | .172 | 19.9 | .582 |
| Paul Maholm* | Pit | sp | 24 | 30 | 0 | .000 | 0 | 11 | .367 | 159 | 5.3 | 31 | 13 | .419 | 82.0 | .591 |
| John Maine | NYN | sp | 25 | 15 | 0 | .000 | 0 | 13 | .867 | 80 | 5.3 | 9 | 0 | .000 | 96.1 | .612 |
| Gary Majewski |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 9 | .346 | 19.0 | .615 |
| Julio Manon | Bal | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 8 | .444 | 26.7 | .546 |
| Shaun Marcum | Tor | sp | 24 | 14 | 0 | .000 | 0 | 5 | .357 | 87 | 6.2 | 17 | 5 | .294 | 77.4 | .606 |
| Carlos Marmol | ChN | sp | 23 | 13 | 0 | .000 | 0 | 5 | .385 | 53 | 4.1 | 20 | 9 | .450 | 61.0 | .545 |
| Mike Maroth* | Det | sp | 28 | 9 | 1 | .111 | 1 | 7 | .778 | 35 | 3.9 | 18 | 2 | .111 | 60.3 | .664 |
| Jason Marquis | StL | sp | 27 | 33 | 2 | .061 | 1 | 12 | .364 | 141 | 4.3 | 25 | 9 | .360 | 73.6 | .619 |
| Sean Marshall* | ChN | sp | 23 | 24 | 0 | .000 | 0 | 13 | .542 | 116 | 4.8 | 22 | 11 | .500 | 86.0 | .604 |
| Damaso Marte* | Pit | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 2 | .083 | 18.4 | .573 |
| Tom Martin* | Col | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 25.1 | .613 |
| Carlos Martinez | Flo | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 23.2 | .627 |
| Pedro Martinez | NYN | sp | 34 | 23 | 0 | .000 | 0 | 13 | .565 | 124 | 5.4 | 10 | 4 | .400 | 90.3 | .637 |
| Tom Mastny | Cle | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 11 | .611 | 18.0 | .623 |
| Juan Mateo | ChN | sp | 23 | 10 | 0 | .000 | 0 | 4 | .400 | 41 | 4.1 | 8 | 4 | .500 | 81.5 | .590 |
| Julio Mateo | Sea | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 19.8 | .624 |
| Scott Mathieson | Phi | sp | 22 | 8 | 0 | .000 | 0 | 0 | .000 | 40 | 5.0 | 3 | 1 | .333 | 58.8 | .618 |
| Joe Mays |   | sp | 30 | 10 | 0 | .000 | 0 | 1 | .100 | 49 | 4.9 | 15 | 6 | .400 | 62.8 | .578 |
| Macay McBride* | Atl | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 51 | 21 | .412 | 19.6 | .540 |
| Brandon McCarthy | ChA | mr | 22 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 24 | 7 | .292 | 31.6 | .608 |
| Seth McClung | Tam | mr | 25 | 15 | 1 | .067 | 1 | 3 | .200 | 100 | 6.7 | 26 | 19 | .731 | 45.5 | .550 |
| Dustin McGowan | Tor | mr | 24 | 3 | 0 | .000 | 0 | 2 | .667 | 10 | 3.3 | 1 | 0 | .000 | 62.3 | .571 |
| Marty McLeary | Pit | mr | 31 | 2 | 0 | .000 | 0 | 0 | .000 | 4 | 2.0 | 2 | 2 | 1.000 | 83.5 | .557 |
| Brian Meadows | Tam | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 11 | .355 | 26.0 | .668 |
| Gil Meche | Sea | sp | 27 | 32 | 0 | .000 | 0 | 13 | .406 | 158 | 4.9 | 23 | 5 | .217 | 89.0 | .607 |
| Brandon Medders | Ari | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 3 | .115 | 21.3 | .620 |
| Kent Mercker* | Cin | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 9 | .529 | 17.1 | .592 |
| Cla Meredith | SD | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.3 | .703 |
| Jose Mesa | Col | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 44 | 14 | .318 | 17.7 | .567 |
| Randy Messenger | Flo | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 22.4 | .639 |
| Dan Miceli | Tam | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 25.6 | .591 |
| Chris Michalak* | Cin | sp | 35 | 6 | 0 | .000 | 0 | 0 | .000 | 25 | 4.2 | 7 | 4 | .571 | 61.9 | .582 |
| Andrew Miller* | Det | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 12.1 | .459 |
| Matt Miller | Cle | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 27.0 | .537 |
| Trever Miller* | Hou | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 10 | .476 | 16.1 | .663 |
| Wade Miller | ChN | sp | 29 | 5 | 0 | .000 | 0 | 2 | .400 | 29 | 5.8 | 4 | 0 | .000 | 89.6 | .551 |
| Kevin Millwood | Tex | sp | 31 | 34 | 1 | .029 | 0 | 18 | .529 | 164 | 4.8 | 34 | 11 | .324 | 87.8 | .657 |
| Eric Milton* | Cin | sp | 30 | 26 | 0 | .000 | 0 | 16 | .615 | 130 | 5.0 | 17 | 3 | .176 | 89.8 | .636 |
| Zach Miner | Det | sp | 24 | 16 | 0 | .000 | 0 | 8 | .500 | 71 | 4.4 | 16 | 7 | .438 | 57.2 | .632 |
| Sergio Mitre | Flo | sp | 25 | 7 | 0 | .000 | 0 | 4 | .571 | 45 | 6.4 | 7 | 1 | .143 | 60.1 | .591 |
| Brian Moehler | Flo | sp | 34 | 21 | 0 | .000 | 0 | 8 | .381 | 91 | 4.3 | 16 | 7 | .438 | 66.9 | .622 |
| Agustin Montero | ChA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 26.6 | .632 |
| Juan Morillo | Col | sp | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 3 | 1 | .333 | 94.0 | .532 |
| Matt Morris | SF | sp | 31 | 33 | 1 | .030 | 1 | 19 | .576 | 141 | 4.3 | 19 | 9 | .474 | 84.2 | .638 |
| Dustin Moseley | LAA | sp | 24 | 2 | 0 | .000 | 0 | 1 | .500 | 1 | 0.5 | 2 | 2 | 1.000 | 53.5 | .626 |
| Guillermo Mota |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 1 | .063 | 19.6 | .635 |
| Jamie Moyer* |   | sp | 43 | 33 | 2 | .061 | 0 | 15 | .455 | 164 | 5.0 | 25 | 9 | .360 | 87.5 | .638 |
| Peter Moylan | Atl | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 25.2 | .677 |
| Edward Mujica | Cle | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 31.1 | .791 |
| Mark Mulder* | StL | sp | 28 | 17 | 0 | .000 | 0 | 1 | .059 | 104 | 6.1 | 15 | 8 | .533 | 75.9 | .597 |
| Terry Mulholland* | Ari | mr | 43 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 37.0 | .703 |
| Scott Munter | SF | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 20.9 | .549 |
| Mike Mussina | NYA | sp | 37 | 32 | 1 | .031 | 1 | 23 | .719 | 233 | 7.3 | 17 | 2 | .118 | 98.3 | .666 |
| Brett Myers | Phi | sp | 25 | 31 | 5 | .161 | 3 | 16 | .516 | 181 | 5.8 | 13 | 6 | .462 | 95.5 | .641 |
| Mike Myers* | NYA | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 7 | .259 | 14.7 | .636 |
| Chris Narveson* | StL | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 0 | 0 | .000 | 95.0 | .526 |
| Joe Nathan | Min | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 20.5 | .689 |
| Jeff Nelson | ChA | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 19.0 | .558 |
| Joe Nelson | KC | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 16.2 | .596 |
| Pat Neshek | Min | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 23.8 | .686 |
| Fernando Nieve | Hou | mr | 23 | 11 | 0 | .000 | 0 | 6 | .545 | 62 | 5.6 | 6 | 2 | .333 | 56.2 | .603 |
| Dustin Nippert | Ari | sp | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 5 | 3 | .600 | 50.0 | .600 |
| Ricky Nolasco | Flo | sp | 23 | 22 | 0 | .000 | 0 | 13 | .591 | 92 | 4.2 | 17 | 13 | .765 | 86.4 | .624 |
| Roberto Novoa | ChN | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 11 | .500 | 23.5 | .594 |
| Leo Nunez | KC | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 25.0 | .590 |
| Mike O'Connor* | Was | sp | 25 | 20 | 0 | .000 | 0 | 10 | .500 | 84 | 4.2 | 10 | 7 | .700 | 86.3 | .593 |
| Eric O'Flaherty* | Sea | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 22.2 | .608 |
| Ryan O'Malley* | ChN | sp | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 6 | 3.0 | 0 | 0 | .000 | 109.0 | .514 |
| Tomo Ohka | Mil | sp | 30 | 18 | 0 | .000 | 0 | 8 | .444 | 96 | 5.3 | 15 | 5 | .333 | 95.7 | .599 |
| Will Ohman* | ChN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 11 | .344 | 19.0 | .573 |
| Darren Oliver* | NYN | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 26.5 | .629 |
| Scott Olsen* | Flo | sp | 22 | 31 | 0 | .000 | 0 | 18 | .581 | 150 | 4.8 | 10 | 1 | .100 | 94.8 | .611 |
| Ramon Ortiz | Was | sp | 33 | 33 | 1 | .030 | 0 | 12 | .364 | 142 | 4.3 | 24 | 9 | .375 | 85.1 | .640 |
| Russ Ortiz |   | sp | 32 | 11 | 0 | .000 | 0 | 0 | .000 | 58 | 5.3 | 22 | 15 | .682 | 33.9 | .586 |
| Chad Orvella | Tam | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 7 | .778 | 34.4 | .539 |
| Franquelis Osoria | LAN | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 24.5 | .572 |
| Roy Oswalt | Hou | sp | 28 | 32 | 1 | .031 | 0 | 15 | .469 | 135 | 4.2 | 19 | 6 | .316 | 89.5 | .662 |
| Akinori Otsuka | Tex | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 18.8 | .670 |
| Vicente Padilla | Tex | sp | 28 | 33 | 1 | .030 | 0 | 15 | .455 | 148 | 4.5 | 36 | 14 | .389 | 93.0 | .621 |
| Jonathan Papelbon | Bos | cl | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 18.1 | .660 |
| Chan Ho Park | SD | sp | 33 | 21 | 2 | .095 | 0 | 7 | .333 | 82 | 3.9 | 21 | 11 | .524 | 81.2 | .629 |
| Chad Paronto | Atl | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 13 | .433 | 18.5 | .634 |
| John Patterson | Was | sp | 28 | 8 | 0 | .000 | 0 | 4 | .500 | 33 | 4.1 | 9 | 3 | .333 | 92.8 | .635 |
| David Pauley | Bos | sp | 23 | 3 | 0 | .000 | 0 | 1 | .333 | 13 | 4.3 | 4 | 1 | .250 | 68.7 | .617 |
| Jake Peavy | SD | sp | 25 | 32 | 5 | .156 | 1 | 18 | .563 | 187 | 5.8 | 18 | 6 | .333 | 99.8 | .638 |
| Mike Pelfrey | NYN | sp | 22 | 4 | 0 | .000 | 0 | 0 | .000 | 16 | 4.0 | 8 | 2 | .250 | 73.8 | .580 |
| Tony Pena | Ari | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 25.9 | .604 |
| Hayden Penn | Bal | sp | 21 | 6 | 0 | .000 | 0 | 0 | .000 | 22 | 3.7 | 5 | 5 | 1.000 | 49.7 | .547 |
| Brad Penny | LAN | sp | 28 | 33 | 1 | .030 | 0 | 17 | .515 | 168 | 5.1 | 28 | 9 | .321 | 82.8 | .634 |
| Joel Peralta | KC | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 8 | .276 | 19.4 | .639 |
| Beltran Perez | Was | mr | 24 | 3 | 0 | .000 | 0 | 2 | .667 | 8 | 2.7 | 2 | 1 | .500 | 87.3 | .565 |
| Juan Perez* | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 | 24.7 | .526 |
| Odalis Perez* |   | mr | 29 | 20 | 1 | .050 | 0 | 6 | .300 | 93 | 4.7 | 23 | 9 | .391 | 58.6 | .625 |
| Oliver Perez* |   | sp | 24 | 22 | 0 | .000 | 0 | 5 | .227 | 111 | 5.0 | 25 | 10 | .400 | 85.3 | .550 |
| Rafael Perez* | Cle | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 2 | .100 | 15.5 | .602 |
| Yusmeiro Petit | Flo | mr | 21 | 1 | 0 | .000 | 0 | 1 | 1.000 | 7 | 7.0 | 3 | 1 | .333 | 36.1 | .654 |
| Andy Pettitte* | Hou | sp | 34 | 35 | 0 | .000 | 0 | 16 | .457 | 152 | 4.3 | 23 | 12 | .522 | 88.3 | .624 |
| Joel Pineiro | Sea | sp | 27 | 25 | 0 | .000 | 0 | 9 | .360 | 112 | 4.5 | 26 | 7 | .269 | 66.2 | .622 |
| Renyel Pinto* | Flo | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 8 | .364 | 21.2 | .539 |
| Cliff Politte | ChA | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 22.0 | .668 |
| Sidney Ponson |   | sp | 29 | 16 | 0 | .000 | 0 | 5 | .313 | 77 | 4.8 | 19 | 10 | .526 | 81.6 | .623 |
| Mark Prior | ChN | sp | 25 | 9 | 0 | .000 | 0 | 3 | .333 | 28 | 3.1 | 6 | 4 | .667 | 88.0 | .588 |
| Scott Proctor | NYA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 6 | .207 | 21.4 | .645 |
| J.J. Putz | Sea | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 18.3 | .684 |
| Chad Qualls | Hou | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 5 | .152 | 16.5 | .621 |
| Brad Radke | Min | sp | 33 | 28 | 1 | .036 | 0 | 9 | .321 | 135 | 4.8 | 26 | 9 | .346 | 80.5 | .670 |
| Elizardo Ramirez | Cin | sp | 23 | 19 | 0 | .000 | 0 | 5 | .263 | 96 | 5.1 | 24 | 10 | .417 | 75.6 | .638 |
| Horacio Ramirez* | Atl | sp | 26 | 14 | 0 | .000 | 0 | 6 | .429 | 80 | 5.7 | 18 | 5 | .278 | 91.1 | .613 |
| Ramon Ramirez | Col | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 24.8 | .600 |
| Darrell Rasner | NYA | sp | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 23 | 7.7 | 0 | 0 | .000 | 73.0 | .648 |
| Jon Rauch | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 10 | .333 | 21.2 | .589 |
| Chris Ray | Bal | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 19.5 | .596 |
| Ken Ray | Atl | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 | 19.5 | .592 |
| Britt Reames | Pit | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 17.8 | .544 |
| Mark Redman* | KC | sp | 32 | 29 | 1 | .034 | 0 | 12 | .414 | 138 | 4.8 | 25 | 10 | .400 | 83.7 | .600 |
| Chris Reitsma | Atl | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 15.0 | .696 |
| Mike Remlinger* | Atl | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 16.4 | .564 |
| Chris Resop | Flo | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 7 | .269 | 18.5 | .598 |
| Anthony Reyes | StL | sp | 24 | 17 | 0 | .000 | 0 | 8 | .471 | 88 | 5.2 | 8 | 6 | .750 | 88.8 | .623 |
| Dennys Reyes* | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 3 | .120 | 14.6 | .618 |
| John Rheinecker* | Tex | sp | 27 | 13 | 0 | .000 | 0 | 5 | .385 | 53 | 4.1 | 14 | 4 | .286 | 79.2 | .625 |
| Arthur Rhodes* | Phi | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 45 | 10 | .222 | 18.8 | .602 |
| Juan Rincon | Min | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 18.4 | .645 |
| Ricardo Rincon* | StL | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 23.0 | .557 |
| Royce Ring* | NYN | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 6 | .857 | 17.1 | .572 |
| David Riske |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 | 19.0 | .601 |
| Mariano Rivera | NYA | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 16.1 | .686 |
| Saul Rivera | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 15 | .577 | 21.9 | .591 |
| Sendy Rleal | Bal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 23.2 | .567 |
| Nate Robertson* | Det | sp | 28 | 32 | 1 | .031 | 0 | 19 | .594 | 155 | 4.8 | 22 | 6 | .273 | 97.8 | .639 |
| Fernando Rodney | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 | 17.5 | .585 |
| Eddy Rodriguez | Bal | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 32.8 | .579 |
| Felix Rodriguez | Was | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 25.3 | .562 |
| Francisco Rodriguez | LAA | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 19.5 | .639 |
| Wandy Rodriguez* | Hou | sp | 27 | 24 | 0 | .000 | 0 | 6 | .250 | 132 | 5.5 | 16 | 6 | .375 | 77.3 | .573 |
| Brian Rogers | Pit | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 30.0 | .614 |
| Kenny Rogers* | Det | sp | 41 | 33 | 3 | .091 | 0 | 22 | .667 | 202 | 6.1 | 20 | 8 | .400 | 98.4 | .620 |
| Davis Romero* | Tor | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 38.1 | .577 |
| J.C. Romero* | LAA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 4 | .121 | 19.4 | .600 |
| Francisco Rosario | Tor | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 7 | 3 | .429 | 40.8 | .562 |
| Josh Rupe | Tex | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 34.6 | .635 |
| Glendon Rusch* | ChN | mr | 31 | 9 | 0 | .000 | 0 | 1 | .111 | 47 | 5.2 | 7 | 5 | .714 | 37.5 | .585 |
| B.J. Ryan* | Tor | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 19.7 | .607 |
| Jae Kuk Ryu | ChN | mr | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 0 | 0 | .000 | 28.2 | .698 |
| Kirk Saarloos | Oak | mr | 27 | 16 | 1 | .063 | 1 | 7 | .438 | 63 | 3.9 | 22 | 5 | .227 | 55.7 | .593 |
| C.C. Sabathia* | Cle | sp | 25 | 28 | 2 | .071 | 2 | 19 | .679 | 180 | 6.4 | 14 | 5 | .357 | 97.3 | .670 |
| Takashi Saito | LAN | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 20.2 | .626 |
| Juan Salas | Tam | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 45.0 | .600 |
| Chris Sampson | Hou | mr | 28 | 3 | 0 | .000 | 0 | 2 | .667 | 13 | 4.3 | 0 | 0 | .000 | 32.6 | .702 |
| Brian Sanches | Phi | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 24.5 | .627 |
| Anibal Sanchez | Flo | sp | 22 | 17 | 1 | .059 | 0 | 10 | .588 | 102 | 6.0 | 13 | 4 | .308 | 99.5 | .620 |
| Duaner Sanchez | NYN | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 25.5 | .600 |
| Jonathan Sanchez* | SF | mr | 23 | 4 | 0 | .000 | 0 | 3 | .750 | 15 | 3.8 | 7 | 1 | .143 | 46.5 | .594 |
| Ervin Santana | LAA | sp | 23 | 33 | 0 | .000 | 0 | 15 | .455 | 172 | 5.2 | 24 | 10 | .417 | 91.9 | .631 |
| Johan Santana* | Min | sp | 27 | 34 | 6 | .176 | 4 | 22 | .647 | 150 | 4.4 | 16 | 5 | .313 | 99.8 | .667 |
| Julio Santana | Phi | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .533 |
| Victor Santos | Pit | sp | 29 | 19 | 1 | .053 | 0 | 7 | .368 | 78 | 4.1 | 24 | 6 | .250 | 47.0 | .631 |
| Dennis Sarfate | Mil | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 4.0 | .750 |
| Scott Sauerbeck* |   | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 7 | .241 | 19.1 | .543 |
| Joe Saunders* | LAA | sp | 25 | 13 | 0 | .000 | 0 | 7 | .538 | 72 | 5.5 | 8 | 2 | .250 | 88.2 | .613 |
| Curt Schilling | Bos | sp | 39 | 31 | 1 | .032 | 1 | 13 | .419 | 177 | 5.7 | 13 | 3 | .231 | 86.4 | .686 |
| Jason Schmidt | SF | sp | 33 | 32 | 1 | .031 | 1 | 21 | .656 | 118 | 3.7 | 18 | 7 | .389 | 103.2 | .630 |
| Scott Schoeneweis* |   | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 19.2 | .617 |
| Chris Schroder | Was | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 22.9 | .632 |
| Rudy Seanez |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 10 | .455 | 25.0 | .613 |
| Bobby Seay* | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 18.0 | .633 |
| Aaron Sele | LAN | sp | 36 | 15 | 0 | .000 | 0 | 7 | .467 | 64 | 4.3 | 14 | 4 | .286 | 58.2 | .624 |
| Jae Seo |   | sp | 29 | 26 | 0 | .000 | 0 | 7 | .269 | 105 | 4.0 | 19 | 9 | .474 | 72.4 | .618 |
| Brian Shackelford* | Cin | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 22.1 | .569 |
| Josh Sharpless | Pit | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 26.2 | .543 |
| Ben Sheets | Mil | sp | 27 | 17 | 0 | .000 | 0 | 10 | .588 | 75 | 4.4 | 9 | 7 | .778 | 96.3 | .693 |
| George Sherrill* | Sea | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 9 | .214 | 17.8 | .557 |
| James Shields | Tam | sp | 24 | 21 | 0 | .000 | 0 | 6 | .286 | 76 | 3.6 | 27 | 11 | .407 | 88.0 | .623 |
| Scot Shields | LAA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 2 | .100 | 20.7 | .649 |
| Jason Shiell | Atl | sp | 29 | 3 | 0 | .000 | 0 | 0 | .000 | 12 | 4.0 | 4 | 0 | .000 | 54.7 | .585 |
| Brian Shouse* |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 3 | .125 | 14.3 | .614 |
| Brian Sikorski |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 30.2 | .666 |
| Carlos Silva | Min | sp | 27 | 31 | 0 | .000 | 0 | 8 | .258 | 142 | 4.6 | 29 | 10 | .345 | 62.3 | .674 |
| Andrew Sisco* | KC | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 10 | .323 | 19.5 | .589 |
| Doug Slaten* | Ari | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.0 | .683 |
| Brian Slocum | Cle | mr | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 18 | 9.0 | 6 | 3 | .500 | 55.0 | .576 |
| Aaron Small | NYA | mr | 34 | 3 | 0 | .000 | 0 | 0 | .000 | 12 | 4.0 | 7 | 1 | .143 | 29.6 | .588 |
| Matt Smith* |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 24.4 | .629 |
| Mike Smith | Min | sp | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 1 | 1 | 1.000 | 50.0 | .560 |
| Travis Smith | Atl | sp | 33 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 2 | 2 | 1.000 | 39.0 | .436 |
| John Smoltz | Atl | sp | 39 | 35 | 1 | .029 | 0 | 21 | .600 | 190 | 5.4 | 26 | 9 | .346 | 96.9 | .652 |
| Ian Snell | Pit | sp | 24 | 32 | 1 | .031 | 1 | 10 | .313 | 128 | 4.0 | 28 | 14 | .500 | 85.8 | .623 |
| Kyle Snyder |   | sp | 28 | 11 | 0 | .000 | 0 | 4 | .364 | 61 | 5.5 | 12 | 4 | .333 | 67.7 | .626 |
| Alay Soler | NYN | sp | 26 | 8 | 0 | .000 | 0 | 3 | .375 | 49 | 6.1 | 8 | 2 | .250 | 84.9 | .585 |
| Rafael Soriano | Sea | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 18.1 | .611 |
| Jorge Sosa |   | mr | 29 | 13 | 1 | .077 | 0 | 7 | .538 | 44 | 3.4 | 15 | 4 | .267 | 42.8 | .628 |
| Jeremy Sowers* | Cle | sp | 23 | 14 | 2 | .143 | 2 | 12 | .857 | 65 | 4.6 | 8 | 2 | .250 | 96.8 | .658 |
| Justin Speier | Tor | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 6 | .231 | 19.6 | .644 |
| Russ Springer | Hou | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 | 23.4 | .625 |
| Chris Spurling |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 17.0 | .623 |
| Jason Standridge | Cin | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 7 | .412 | 21.4 | .542 |
| Mike Stanton* |   | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 17.8 | .627 |
| Tim Stauffer | SD | sp | 24 | 1 | 0 | .000 | 0 | 1 | 1.000 | 3 | 3.0 | 0 | 0 | .000 | 101.0 | .653 |
| Steve Stemle | KC | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 49.0 | .546 |
| Brian Stokes | Tam | sp | 26 | 4 | 0 | .000 | 0 | 0 | .000 | 18 | 4.5 | 6 | 2 | .333 | 72.0 | .608 |
| Huston Street | Oak | cl | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 18.3 | .675 |
| Eric Stults* | LAN | mr | 26 | 2 | 1 | .500 | 0 | 2 | 1.000 | 11 | 5.5 | 0 | 0 | .000 | 91.0 | .643 |
| Tanyon Sturtze | NYA | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 22.3 | .583 |
| Jeff Suppan | StL | sp | 31 | 32 | 1 | .031 | 0 | 16 | .500 | 207 | 6.5 | 27 | 10 | .370 | 88.0 | .625 |
| Brian Sweeney | SD | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 7 | .500 | 24.5 | .598 |
| Jon Switzer* | Tam | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 | 19.1 | .583 |
| Brian Tallet* | Tor | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 12 | 12.0 | 16 | 6 | .375 | 27.9 | .595 |
| Taylor Tankersley* | Flo | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 10 | .417 | 18.9 | .568 |
| Jack Taschner* | SF | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 24.0 | .625 |
| Jordan Tata | Det | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 23.4 | .600 |
| Ty Taubenheim | Tor | sp | 23 | 7 | 0 | .000 | 0 | 1 | .143 | 38 | 5.4 | 9 | 8 | .889 | 61.9 | .591 |
| Julian Tavarez | Bos | mr | 33 | 6 | 0 | .000 | 0 | 3 | .500 | 22 | 3.7 | 35 | 11 | .314 | 33.0 | .598 |
| Robinson Tejeda | Tex | sp | 24 | 14 | 0 | .000 | 0 | 7 | .500 | 72 | 5.1 | 10 | 4 | .400 | 85.1 | .593 |
| Brad Thompson | StL | mr | 24 | 1 | 1 | 1.000 | 1 | 1 | 1.000 | 7 | 7.0 | 8 | 2 | .250 | 28.2 | .593 |
| Mike Thompson | SD | sp | 25 | 16 | 1 | .063 | 1 | 8 | .500 | 78 | 4.9 | 15 | 10 | .667 | 81.5 | .625 |
| John Thomson | Atl | sp | 32 | 15 | 0 | .000 | 0 | 7 | .467 | 66 | 4.4 | 11 | 3 | .273 | 83.9 | .631 |
| Matt Thornton* | ChA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 19.3 | .631 |
| Mike Timlin | Bos | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 45 | 15 | .333 | 17.4 | .683 |
| Brett Tomko | LAN | mr | 33 | 15 | 1 | .067 | 1 | 10 | .667 | 101 | 6.7 | 18 | 6 | .333 | 53.3 | .652 |
| Salomon Torres | Pit | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 44 | 19 | .432 | 17.6 | .619 |
| Josh Towers | Tor | sp | 29 | 12 | 0 | .000 | 0 | 3 | .250 | 65 | 5.4 | 10 | 8 | .800 | 66.1 | .654 |
| Billy Traber* | Was | sp | 26 | 8 | 0 | .000 | 0 | 3 | .375 | 47 | 5.9 | 14 | 6 | .429 | 46.1 | .614 |
| Sean Tracey | ChA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 22.9 | .544 |
| Steve Trachsel | NYN | sp | 35 | 30 | 0 | .000 | 0 | 7 | .233 | 160 | 5.3 | 34 | 13 | .382 | 76.9 | .599 |
| Derrick Turnbow | Mil | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 10 | .385 | 19.0 | .575 |
| Jose Valverde | Ari | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 21.6 | .594 |
| Jermaine Van Buren | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 32.3 | .502 |
| Claudio Vargas | Ari | sp | 28 | 30 | 0 | .000 | 0 | 13 | .433 | 128 | 4.3 | 24 | 8 | .333 | 84.6 | .626 |
| Jason Vargas* | Flo | mr | 23 | 5 | 0 | .000 | 0 | 2 | .400 | 20 | 4.0 | 5 | 3 | .600 | 48.0 | .580 |
| Javier Vazquez | ChA | sp | 29 | 32 | 3 | .094 | 0 | 21 | .656 | 171 | 5.3 | 21 | 7 | .333 | 99.0 | .638 |
| Mike Venafro* | Col | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 21.3 | .578 |
| Jose Veras | NYA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 20.6 | .559 |
| Justin Verlander | Det | sp | 23 | 30 | 0 | .000 | 0 | 16 | .533 | 134 | 4.5 | 28 | 11 | .393 | 94.8 | .626 |
| Carlos Villanueva | Mil | sp | 22 | 6 | 0 | .000 | 0 | 3 | .500 | 32 | 5.3 | 4 | 2 | .500 | 86.2 | .681 |
| Oscar Villarreal | Atl | mr | 24 | 4 | 0 | .000 | 0 | 2 | .500 | 25 | 6.3 | 8 | 2 | .250 | 31.3 | .648 |
| Ron Villone* | NYA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 28.9 | .585 |
| Luis Vizcaino | Ari | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 0 | .000 | 20.9 | .623 |
| Ryan Vogelsong | Pit | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 35.4 | .563 |
| Edinson Volquez | Tex | sp | 22 | 8 | 0 | .000 | 0 | 1 | .125 | 25 | 3.1 | 3 | 0 | .000 | 74.3 | .618 |
| Doug Waechter | Tam | sp | 25 | 10 | 0 | .000 | 0 | 6 | .600 | 32 | 3.2 | 11 | 3 | .273 | 87.5 | .633 |
| Billy Wagner* | NYN | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 19.5 | .634 |
| Ryan Wagner | Was | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 25.7 | .584 |
| Adam Wainwright | StL | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 4 | .190 | 25.4 | .629 |
| Tim Wakefield | Bos | sp | 39 | 23 | 0 | .000 | 0 | 10 | .435 | 106 | 4.6 | 20 | 7 | .350 | 85.0 | .606 |
| Jamie Walker* | Det | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 4 | .125 | 11.5 | .665 |
| Pete Walker | Tor | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 | 30.5 | .606 |
| Tyler Walker |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 19.1 | .625 |
| Les Walrond* | ChN | mr | 29 | 2 | 0 | .000 | 0 | 1 | .500 | 13 | 6.5 | 7 | 2 | .286 | 38.4 | .594 |
| Chien-Ming Wang | NYA | sp | 26 | 33 | 4 | .121 | 0 | 22 | .667 | 191 | 5.8 | 17 | 6 | .353 | 94.8 | .632 |
| John Wasdin | Tex | sp | 33 | 5 | 1 | .200 | 1 | 3 | .600 | 22 | 4.4 | 3 | 1 | .333 | 98.6 | .617 |
| Jarrod Washburn* | Sea | sp | 31 | 31 | 2 | .065 | 1 | 20 | .645 | 123 | 4.0 | 20 | 3 | .150 | 88.1 | .625 |
| David Weathers | Cin | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 16.5 | .627 |
| Jeff Weaver |   | sp | 29 | 31 | 2 | .065 | 0 | 11 | .355 | 124 | 4.0 | 23 | 6 | .261 | 82.1 | .642 |
| Jered Weaver | LAA | sp | 23 | 19 | 2 | .105 | 2 | 12 | .632 | 90 | 4.7 | 5 | 2 | .400 | 94.7 | .621 |
| Brandon Webb | Ari | sp | 27 | 33 | 5 | .152 | 0 | 20 | .606 | 183 | 5.5 | 16 | 8 | .500 | 98.7 | .658 |
| Todd Wellemeyer |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 9 | .321 | 33.0 | .546 |
| David Wells* |   | sp | 43 | 13 | 1 | .077 | 1 | 9 | .692 | 67 | 5.2 | 7 | 1 | .143 | 85.7 | .675 |
| Kip Wells |   | sp | 29 | 9 | 0 | .000 | 0 | 1 | .111 | 25 | 2.8 | 12 | 4 | .333 | 57.2 | .614 |
| Jake Westbrook | Cle | sp | 28 | 32 | 4 | .125 | 1 | 21 | .656 | 217 | 6.8 | 35 | 8 | .229 | 95.3 | .646 |
| Dan Wheeler | Hou | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 18.6 | .619 |
| Rick White |   | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 11 | .344 | 19.5 | .622 |
| Bob Wickman |   | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 16.4 | .655 |
| Dave Williams* |   | sp | 27 | 13 | 1 | .077 | 0 | 6 | .462 | 68 | 5.2 | 12 | 4 | .333 | 82.7 | .631 |
| Jerome Williams | ChN | mr | 24 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 4 | 1 | .250 | 72.0 | .579 |
| Todd Williams | Bal | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 9 | .225 | 17.1 | .634 |
| Woody Williams | SD | sp | 39 | 24 | 0 | .000 | 0 | 12 | .500 | 117 | 4.9 | 19 | 7 | .368 | 85.8 | .650 |
| Scott Williamson |   | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 5 | .200 | 21.7 | .595 |
| Dontrelle Willis* | Flo | sp | 24 | 34 | 1 | .029 | 0 | 21 | .618 | 180 | 5.3 | 21 | 13 | .619 | 102.8 | .603 |
| Brian Wilson | SF | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 9 | .409 | 17.9 | .577 |
| C.J. Wilson* | Tex | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 10 | .588 | 18.0 | .614 |
| Kris Wilson | NYA | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 1 | 0 | .000 | 34.0 | .618 |
| Jason Windsor | Oak | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 5 | 2 | .400 | 58.7 | .591 |
| Joe Winkelsas | Mil | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 24.8 | .535 |
| Matt Wise | Mil | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 8 | .400 | 18.2 | .630 |
| Jay Witasick | Oak | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 0 | .000 | 40.5 | .519 |
| Randy Wolf* | Phi | sp | 29 | 12 | 0 | .000 | 0 | 2 | .167 | 73 | 6.1 | 11 | 4 | .364 | 64.7 | .590 |
| Kerry Wood | ChN | sp | 29 | 4 | 0 | .000 | 0 | 1 | .250 | 18 | 4.5 | 1 | 1 | 1.000 | 70.8 | .611 |
| Mike Wood | KC | mr | 26 | 7 | 0 | .000 | 0 | 3 | .429 | 35 | 5.0 | 20 | 9 | .450 | 41.1 | .642 |
| Jake Woods* | Sea | mr | 24 | 8 | 0 | .000 | 0 | 4 | .500 | 20 | 2.5 | 15 | 7 | .467 | 43.8 | .593 |
| Tim Worrell | SF | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 14.8 | .617 |
| Jamey Wright | SF | sp | 31 | 21 | 3 | .143 | 1 | 10 | .476 | 95 | 4.5 | 14 | 7 | .500 | 63.3 | .614 |
| Jaret Wright | NYA | sp | 30 | 27 | 1 | .037 | 1 | 10 | .370 | 163 | 6.0 | 29 | 9 | .310 | 80.7 | .610 |
| Michael Wuertz | ChN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 22.4 | .630 |
| Esteban Yan |   | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 27.9 | .580 |
| Tyler Yates | Atl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 23.1 | .606 |
| Shane Youman* | Pit | sp | 26 | 3 | 0 | .000 | 0 | 1 | .333 | 6 | 2.0 | 1 | 1 | 1.000 | 90.3 | .550 |
| Chris Young | SD | sp | 27 | 31 | 2 | .065 | 2 | 18 | .581 | 129 | 4.2 | 19 | 7 | .368 | 93.2 | .618 |
| Carlos Zambrano | ChN | sp | 25 | 33 | 1 | .030 | 1 | 19 | .576 | 178 | 5.4 | 26 | 12 | .462 | 106.3 | .587 |
| Victor Zambrano | NYN | sp | 30 | 5 | 0 | .000 | 0 | 1 | .200 | 28 | 5.6 | 3 | 0 | .000 | 81.8 | .548 |
| Barry Zito* | Oak | sp | 28 | 34 | 0 | .000 | 0 | 22 | .647 | 145 | 4.3 | 32 | 8 | .250 | 101.0 | .607 |
| Joel Zumaya | Det | mr | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 5 | .238 | 17.6 | .607 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | PCH/G | STR% |
| David Aardsma | ChN | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 19 | 8 | .421 | 30 | 30 | 7 | 24.4 | .596 |
| Winston Abreu | Bal | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 3 | .750 | 8 | 8 | 3 | 37.3 | .557 |
| Jeremy Accardo |   | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 42 | 17 | .405 | 35 | 35 | 11 | 23.2 | .630 |
| Jon Adkins | SD | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 50 | 19 | .380 | 49 | 49 | 8 | 23.5 | .621 |
| Jeremy Affeldt* |   | mr | 27 | 3 | 0 | .000 | 3 | 1.000 | 5 | 46 | 17 | .370 | 56 | 47 | 17 | 33.7 | .593 |
| Matt Albers | Hou | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 92.5 | .611 |
| Antonio Alfonseca | Tex | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 7 | 7 | 2 | 19.7 | .587 |
| Steve Andrade | KC | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 0 | 19.0 | .421 |
| Greg Aquino | Ari | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 45 | 17 | .378 | 47 | 47 | 2 | 32.1 | .594 |
| Tony Armas | Was | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 2 | 1 | 78.2 | .614 |
| Bronson Arroyo | Cin | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 1 | 0 | 97.8 | .627 |
| Miguel Asencio | Col | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 88.0 | .545 |
| Ezequiel Astacio | Hou | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 | 28.0 | .625 |
| Pedro Astacio | Was | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 1 | 1 | 79.6 | .621 |
| Brandon Backe | Hou | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 81.3 | .597 |
| Cha Seung Baek | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 89.2 | .587 |
| Danys Baez |   | mr | 28 | 7 | 1 | .143 | 5 | .714 | 7 | 30 | 7 | .233 | 58 | 58 | 16 | 18.4 | .640 |
| Jeff Bajenaru | Ari | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 2 | 26.5 | .528 |
| Scott Baker | Min | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 75.4 | .666 |
| Brian Bannister | NYN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 85.2 | .571 |
| Kevin Barry | Atl | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 11 | 6 | .545 | 14 | 13 | 5 | 26.1 | .579 |
| Miguel Batista | Ari | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 34 | 1 | 1 | 76.9 | .595 |
| Rick Bauer | Tex | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 2 | 71 | 23 | .324 | 56 | 55 | 6 | 24.7 | .611 |
| Denny Bautista |   | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 9 | 1 | 1 | 68.0 | .609 |
| Jonah Bayliss | Pit | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 2 | .250 | 19 | 19 | 8 | 27.6 | .569 |
| T.J. Beam | NYA | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 11 | 11 | 5 | 20.3 | .596 |
| Josh Beckett | Bos | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.6 | .619 |
| Erik Bedard* | Bal | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.0 | .614 |
| Joe Beimel* | LAN | mr | 29 | 9 | 2 | .222 | 4 | .444 | 12 | 29 | 10 | .345 | 74 | 74 | 21 | 16.9 | .579 |
| Matt Belisle | Cin | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 1 | 30 | 13 | .433 | 36 | 34 | 9 | 26.9 | .600 |
| Heath Bell | NYN | mr | 28 | 5 | 4 | .800 | 1 | .200 | 2 | 9 | 4 | .444 | 21 | 21 | 11 | 25.3 | .632 |
| Armando Benitez | SF | cl | 33 | 26 | 20 | .769 | 5 | .192 | 4 | 44 | 15 | .341 | 55 | 55 | 34 | 19.5 | .600 |
| Joaquin Benoit | Tex | mr | 28 | 2 | 0 | .000 | 1 | .500 | 2 | 47 | 17 | .362 | 53 | 53 | 14 | 28.8 | .600 |
| Kris Benson | Bal | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 91.9 | .611 |
| Jason Bergmann | Was | mr | 24 | 4 | 0 | .000 | 3 | .750 | 1 | 21 | 11 | .524 | 33 | 27 | 5 | 38.3 | .623 |
| Adam Bernero |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 74.7 | .688 |
| Rafael Betancourt | Cle | mr | 31 | 8 | 5 | .625 | 3 | .375 | 16 | 44 | 12 | .273 | 60 | 60 | 26 | 18.9 | .709 |
| Chad Billingsley | LAN | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 96.8 | .566 |
| Kurt Birkins* | Bal | mr | 25 | 3 | 1 | .333 | 2 | .667 | 7 | 26 | 2 | .077 | 33 | 33 | 7 | 20.8 | .573 |
| Joe Blanton | Oak | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 93.8 | .639 |
| Jeremy Bonderman | Det | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 96.5 | .642 |
| Boof Bonser | Min | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 82.1 | .639 |
| Chris Booker |   | mr | 29 | 3 | 1 | .333 | 1 | .333 | 0 | 2 | 0 | .000 | 13 | 13 | 5 | 19.2 | .667 |
| Chris Bootcheck | LAA | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 6 | 6 | 1 | 60.5 | .526 |
| Dave Borkowski | Hou | mr | 29 | 4 | 4 | 1.000 | 0 | .000 | 2 | 34 | 16 | .471 | 54 | 54 | 17 | 30.0 | .655 |
| Joe Borowski | Flo | cl | 35 | 32 | 24 | .750 | 8 | .250 | 2 | 55 | 15 | .273 | 71 | 71 | 60 | 19.5 | .626 |
| Micah Bowie* | Was | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 3 | 1.000 | 10 | 10 | 6 | 23.5 | .583 |
| Chad Bradford | NYN | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 3 | 38 | 15 | .395 | 39 | 39 | 6 | 23.2 | .676 |
| Ryan Braun | KC | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 2 | .286 | 5 | 5 | 1 | 28.6 | .643 |
| Bill Bray* |   | mr | 23 | 3 | 1 | .333 | 1 | .333 | 11 | 31 | 6 | .194 | 53 | 53 | 16 | 18.2 | .602 |
| Dewon Brazelton | SD | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 5 | .625 | 5 | 3 | 0 | 52.2 | .605 |
| Craig Breslow* | Bos | mr | 25 | 2 | 1 | .500 | 1 | .500 | 1 | 5 | 4 | .800 | 6 | 6 | 2 | 20.3 | .557 |
| Eude Brito* | Phi | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 57.5 | .530 |
| Chris Britton | Bal | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 3 | 18 | 4 | .222 | 37 | 37 | 20 | 21.5 | .640 |
| Doug Brocail | SD | mr | 39 | 1 | 1 | 1.000 | 0 | .000 | 1 | 7 | 2 | .286 | 11 | 11 | 3 | 20.9 | .626 |
| Jim Brower |   | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 10 | 10 | 1 | 31.4 | .535 |
| Andrew Brown | Cle | mr | 25 | 2 | 1 | .500 | 1 | .500 | 7 | 16 | 8 | .500 | 21 | 21 | 11 | 14.9 | .575 |
| Jonathan Broxton | LAN | mr | 22 | 9 | 3 | .333 | 6 | .667 | 15 | 36 | 18 | .500 | 74 | 74 | 24 | 19.5 | .624 |
| Brian Bruney | NYA | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 1 | .250 | 7 | 7 | 1 | 29.7 | .505 |
| Taylor Buchholz | Hou | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 1 | 1 | 78.8 | .629 |
| Mark Buehrle* | ChA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 86.1 | .636 |
| Ambiorix Burgos | KC | cl | 22 | 13 | 3 | .231 | 10 | .769 | 15 | 52 | 22 | .423 | 79 | 78 | 25 | 22.0 | .594 |
| A.J. Burnett | Tor | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 88.2 | .626 |
| Mike Burns |   | mr | 27 | 3 | 1 | .333 | 1 | .333 | 1 | 7 | 1 | .143 | 14 | 14 | 3 | 24.0 | .610 |
| Brian Burres* | Bal | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 5 | 3 | .600 | 4 | 4 | 0 | 11.3 | .622 |
| Dave Bush | Mil | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 98.7 | .665 |
| Paul Byrd | Cle | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 87.0 | .670 |
| Tim Byrdak* | Bal | mr | 32 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 3 | .500 | 9 | 9 | 1 | 26.0 | .474 |
| Daniel Cabrera | Bal | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 94.6 | .565 |
| Fernando Cabrera | Cle | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 58 | 16 | .276 | 43 | 43 | 6 | 26.7 | .575 |
| Matt Cain | SF | sp | 21 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 33 | 2 | 2 | 92.8 | .611 |
| Kiko Calero | Oak | mr | 31 | 8 | 2 | .250 | 4 | .500 | 19 | 53 | 15 | .283 | 67 | 67 | 18 | 17.9 | .601 |
| Shawn Camp | Tam | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 4 | 82 | 48 | .585 | 63 | 63 | 3 | 25.6 | .637 |
| Jose Capellan | Mil | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 1 | 38 | 19 | .500 | 47 | 47 | 9 | 26.1 | .613 |
| Matt Capps | Pit | mr | 22 | 1 | 0 | .000 | 0 | .000 | 1 | 77 | 26 | .338 | 75 | 75 | 21 | 20.4 | .691 |
| Chris Capuano* | Mil | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 96.9 | .660 |
| Fausto Carmona | Cle | mr | 22 | 2 | 0 | .000 | 0 | .000 | 3 | 17 | 6 | .353 | 34 | 27 | 15 | 32.6 | .625 |
| Chris Carpenter | StL | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.0 | .664 |
| Giovanni Carrara | LAN | mr | 38 | 1 | 1 | 1.000 | 0 | .000 | 0 | 12 | 7 | .583 | 15 | 15 | 3 | 28.3 | .651 |
| Hector Carrasco | LAA | mr | 36 | 0 | 0 | .000 | 0 | .000 | 3 | 72 | 27 | .375 | 56 | 53 | 7 | 33.1 | .625 |
| Lance Carter | LAN | mr | 31 | 2 | 1 | .500 | 1 | .500 | 0 | 3 | 1 | .333 | 4 | 4 | 3 | 12.0 | .604 |
| Santiago Casilla | Oak | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 15.0 | .600 |
| Scott Cassidy | SD | mr | 30 | 3 | 1 | .333 | 2 | .667 | 3 | 16 | 6 | .375 | 40 | 40 | 15 | 18.2 | .633 |
| Fabio Castro* |   | mr | 21 | 0 | 0 | .000 | 0 | .000 | 3 | 26 | 1 | .038 | 29 | 29 | 6 | 25.8 | .585 |
| Gustavo Chacin* | Tor | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 80.4 | .597 |
| Shawn Chacon |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 27 | 7 | 1 | 61.9 | .576 |
| Bruce Chen* | Bal | mr | 29 | 2 | 0 | .000 | 0 | .000 | 1 | 37 | 14 | .378 | 49 | 37 | 7 | 36.5 | .618 |
| Jason Childers | Tam | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 4 | 4 | 1 | 40.0 | .606 |
| Randy Choate* | Ari | mr | 30 | 3 | 0 | .000 | 0 | .000 | 4 | 4 | 1 | .250 | 21 | 21 | 4 | 15.4 | .676 |
| Vinnie Chulk |   | mr | 27 | 4 | 3 | .750 | 1 | .250 | 7 | 17 | 4 | .235 | 37 | 37 | 13 | 21.4 | .615 |
| Brandon Claussen* | Cin | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 79.5 | .588 |
| Roger Clemens | Hou | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 95.2 | .648 |
| Matt Clement | Bos | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 90.8 | .562 |
| Todd Coffey | Cin | mr | 25 | 11 | 4 | .364 | 7 | .636 | 16 | 49 | 22 | .449 | 88 | 88 | 24 | 17.9 | .612 |
| Bartolo Colon | LAA | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 87.9 | .659 |
| Roman Colon | Det | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 0 | 11 | 4 | .364 | 19 | 18 | 10 | 35.1 | .632 |
| Clay Condrey | Phi | mr | 30 | 0 | 0 | .000 | 0 | .000 | 2 | 13 | 4 | .308 | 19 | 19 | 2 | 24.9 | .637 |
| Jose Contreras | ChA | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 90.2 | .642 |
| Aaron Cook | Col | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 81.8 | .645 |
| Roy Corcoran | Was | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 2 | .500 | 5 | 5 | 2 | 20.2 | .653 |
| Tim Corcoran | Tam | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 4 | .800 | 24 | 8 | 1 | 64.2 | .580 |
| Chad Cordero | Was | cl | 24 | 33 | 31 | .939 | 2 | .061 | 3 | 53 | 10 | .189 | 78 | 78 | 60 | 19.0 | .645 |
| Francisco Cordero |   | cl | 31 | 14 | 8 | .571 | 3 | .214 | 16 | 31 | 6 | .194 | 80 | 80 | 27 | 18.9 | .623 |
| Bryan Corey |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 4 | .571 | 7 | 7 | 2 | 31.6 | .629 |
| Lance Cormier | Atl | mr | 25 | 3 | 1 | .333 | 2 | .667 | 1 | 7 | 4 | .571 | 32 | 23 | 5 | 38.8 | .589 |
| Rheal Cormier* |   | mr | 39 | 5 | 1 | .200 | 3 | .600 | 10 | 29 | 7 | .241 | 56 | 56 | 18 | 17.8 | .598 |
| Manuel Corpas | Col | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 8 | 5 | .625 | 18 | 18 | 5 | 23.7 | .688 |
| Kevin Correia | SF | mr | 25 | 3 | 2 | .667 | 1 | .333 | 0 | 45 | 18 | .400 | 57 | 57 | 16 | 26.1 | .636 |
| David Cortes | Col | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 1 | 16 | 7 | .438 | 31 | 31 | 11 | 21.3 | .652 |
| Neal Cotts* | ChA | mr | 26 | 8 | 1 | .125 | 5 | .625 | 12 | 38 | 11 | .289 | 68 | 68 | 8 | 20.0 | .599 |
| Jesse Crain | Min | mr | 24 | 8 | 5 | .625 | 1 | .125 | 7 | 33 | 11 | .333 | 53 | 53 | 27 | 18.2 | .665 |
| Francisco Cruceta | Sea | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 74.0 | .622 |
| Juan Cruz | Ari | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 35 | 20 | 5 | 52.1 | .591 |
| Casey Daigle | Ari | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 1 | 0 | .000 | 6 | 6 | 3 | 18.0 | .611 |
| Kyle Davies | Atl | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 67.4 | .591 |
| Doug Davis* | Mil | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 103.2 | .594 |
| Jason Davis | Cle | mr | 26 | 1 | 0 | .000 | 0 | .000 | 1 | 39 | 8 | .205 | 33 | 33 | 5 | 31.9 | .657 |
| Zach Day |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 71.8 | .599 |
| Jorge De La Rosa* |   | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 1 | .143 | 18 | 5 | 1 | 65.3 | .554 |
| Manny Delcarmen | Bos | mr | 24 | 2 | 1 | .500 | 1 | .500 | 2 | 29 | 8 | .276 | 31 | 31 | 7 | 25.9 | .640 |
| Chris Demaria | Mil | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 6 | 6 | 3 | 30.2 | .597 |
| Ryan Dempster | ChN | cl | 29 | 31 | 24 | .774 | 7 | .226 | 5 | 42 | 9 | .214 | 66 | 66 | 44 | 19.6 | .596 |
| Elmer Dessens |   | mr | 35 | 7 | 5 | .714 | 2 | .286 | 2 | 27 | 8 | .296 | 44 | 44 | 23 | 20.6 | .664 |
| Joey Devine | Atl | mr | 22 | 2 | 2 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 8 | 8 | 5 | 21.8 | .500 |
| R.A. Dickey | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 87.0 | .701 |
| Lenny DiNardo* | Bos | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 12 | 6 | 5 | 52.3 | .585 |
| Scott Dohmann |   | mr | 28 | 2 | 1 | .500 | 1 | .500 | 0 | 27 | 7 | .259 | 33 | 33 | 14 | 22.9 | .559 |
| Brendan Donnelly | LAA | mr | 34 | 8 | 4 | .500 | 3 | .375 | 8 | 25 | 5 | .200 | 56 | 56 | 33 | 19.7 | .618 |
| Octavio Dotel | NYA | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 3 | 3 | 0 | 33.3 | .530 |
| Scott Downs* | Tor | mr | 30 | 0 | 0 | .000 | 0 | .000 | 3 | 52 | 24 | .462 | 49 | 44 | 8 | 32.0 | .600 |
| Ryan Drese | Was | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 60.0 | .483 |
| Justin Duchscherer | Oak | mr | 28 | 3 | 2 | .667 | 1 | .333 | 8 | 17 | 2 | .118 | 45 | 45 | 26 | 20.0 | .646 |
| Brandon Duckworth | KC | sp | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 1 | 1 | 67.8 | .620 |
| Zach Duke* | Pit | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 36 | 2 | 2 | 84.1 | .627 |
| Scott Dunn | Tam | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 6 | 6 | 3 | 30.0 | .583 |
| Chad Durbin | Det | mr | 28 | 1 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 6 | 6 | 5 | 17.7 | .613 |
| Adam Eaton | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 79.5 | .618 |
| Joey Eischen* | Was | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 15 | 15 | 4 | 23.8 | .538 |
| Scott Elarton | KC | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 81.8 | .603 |
| Alan Embree* | SD | mr | 36 | 8 | 0 | .000 | 3 | .375 | 22 | 27 | 8 | .296 | 71 | 71 | 12 | 14.4 | .630 |
| Scott Erickson | NYA | mr | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 11.0 | .636 |
| Kelvim Escobar | LAA | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 92.9 | .645 |
| Shawn Estes* | SD | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 103.0 | .680 |
| Seth Etherton | KC | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 69.0 | .536 |
| Dana Eveland* | Mil | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 100.8 | .597 |
| Scott Eyre* | ChN | mr | 34 | 9 | 3 | .333 | 5 | .556 | 7 | 42 | 16 | .381 | 61 | 61 | 25 | 19.6 | .617 |
| Willie Eyre | Min | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 49 | 21 | .429 | 43 | 43 | 14 | 27.9 | .607 |
| Brian Falkenborg | StL | mr | 28 | 2 | 0 | .000 | 1 | .500 | 0 | 3 | 1 | .333 | 5 | 5 | 3 | 17.4 | .586 |
| Kyle Farnsworth | NYA | mr | 30 | 12 | 1 | .083 | 10 | .833 | 23 | 29 | 12 | .414 | 78 | 78 | 15 | 18.7 | .612 |
| Jeff Fassero* | SF | mr | 43 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 2 | .250 | 10 | 9 | 3 | 28.3 | .580 |
| Ryan Feierabend* | Sea | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 102.0 | .578 |
| Scott Feldman | Tex | mr | 23 | 8 | 2 | .250 | 6 | .750 | 8 | 34 | 16 | .471 | 43 | 43 | 15 | 19.7 | .641 |
| Pedro Feliciano* | NYN | mr | 29 | 12 | 3 | .250 | 6 | .500 | 22 | 36 | 12 | .333 | 76 | 76 | 14 | 16.7 | .591 |
| Nate Field | Col | mr | 30 | 3 | 2 | .667 | 1 | .333 | 2 | 6 | 4 | .667 | 7 | 7 | 2 | 17.0 | .571 |
| Randy Flores* | StL | mr | 30 | 9 | 3 | .333 | 6 | .667 | 20 | 36 | 12 | .333 | 77 | 77 | 21 | 14.4 | .577 |
| Ron Flores* | Oak | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 19 | 6 | .316 | 20 | 20 | 8 | 25.0 | .641 |
| Gavin Floyd | Phi | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 67.9 | .565 |
| Josh Fogg | Col | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 85.1 | .631 |
| Casey Fossum* | Tam | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 83.8 | .609 |
| Keith Foulke | Bos | mr | 33 | 6 | 1 | .167 | 3 | .500 | 5 | 30 | 13 | .433 | 47 | 47 | 17 | 19.0 | .658 |
| Jeff Francis* | Col | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 87.2 | .619 |
| Frank Francisco | Tex | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 3 | 3 | 2 | 29.0 | .644 |
| Ryan Franklin |   | mr | 33 | 8 | 2 | .250 | 5 | .625 | 13 | 47 | 17 | .362 | 71 | 71 | 17 | 17.6 | .645 |
| Wayne Franklin* | Atl | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 4 | 4 | 2 | 18.3 | .452 |
| Jason Frasor | Tor | mr | 28 | 4 | 3 | .750 | 1 | .250 | 15 | 23 | 6 | .261 | 52 | 52 | 19 | 21.9 | .625 |
| Emiliano Fruto | Sea | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 16 | 4 | .250 | 21 | 21 | 8 | 40.8 | .564 |
| Brian Fuentes* | Col | cl | 30 | 32 | 26 | .813 | 6 | .188 | 3 | 37 | 7 | .189 | 73 | 73 | 54 | 19.1 | .595 |
| Aaron Fultz* | Phi | mr | 32 | 0 | 0 | .000 | 0 | .000 | 4 | 40 | 14 | .350 | 55 | 54 | 6 | 22.5 | .608 |
| Kason Gabbard* | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 100.5 | .535 |
| Mike Gallo* | Hou | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 3 | .375 | 13 | 13 | 5 | 21.4 | .572 |
| Freddy Garcia | ChA | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.7 | .661 |
| Jose Garcia | Flo | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 1 | 36.3 | .596 |
| Jon Garland | ChA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 80.3 | .667 |
| Matt Garza | Min | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 85.6 | .606 |
| Chad Gaudin | Oak | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 39 | 11 | .282 | 35 | 35 | 4 | 27.3 | .553 |
| Geoff Geary | Phi | mr | 29 | 0 | 0 | .000 | 0 | .000 | 3 | 43 | 17 | .395 | 62 | 62 | 5 | 21.7 | .664 |
| Franklyn German | Flo | mr | 26 | 2 | 1 | .500 | 1 | .500 | 3 | 8 | 1 | .125 | 18 | 18 | 8 | 20.5 | .553 |
| Justin Germano | Cin | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 64.0 | .672 |
| Tom Glavine* | NYN | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 81.9 | .639 |
| Jimmy Gobble* | KC | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 42 | 16 | .381 | 47 | 41 | 3 | 30.1 | .611 |
| Edgar Gonzalez | Ari | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 13 | 7 | .538 | 18 | 13 | 6 | 43.6 | .665 |
| Enrique Gonzalez | Ari | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 2 | 2 | 84.6 | .640 |
| Geremi Gonzalez |   | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 14 | 3 | .214 | 33 | 29 | 11 | 35.2 | .632 |
| Mike Gonzalez* | Pit | cl | 28 | 20 | 14 | .700 | 6 | .300 | 5 | 28 | 7 | .250 | 59 | 59 | 31 | 21.6 | .591 |
| Tom Gordon | Phi | cl | 38 | 34 | 22 | .647 | 12 | .353 | 1 | 43 | 21 | .488 | 62 | 62 | 46 | 19.4 | .610 |
| Tom Gorzelanny* | Pit | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 97.7 | .593 |
| Mike Gosling* | Cin | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 13.0 | .615 |
| John Grabow* | Pit | mr | 27 | 5 | 2 | .400 | 3 | .600 | 2 | 56 | 23 | .411 | 58 | 58 | 13 | 23.6 | .614 |
| Danny Graves | Cle | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 5 | 1.000 | 4 | 4 | 1 | 28.5 | .561 |
| Sean Green | Sea | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 33 | 8 | .242 | 26 | 26 | 8 | 27.0 | .575 |
| Kevin Gregg | LAA | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 29 | 10 | .345 | 36 | 33 | 12 | 35.9 | .639 |
| Jason Grilli | Det | mr | 29 | 1 | 0 | .000 | 0 | .000 | 5 | 34 | 9 | .265 | 57 | 57 | 18 | 20.7 | .600 |
| Jason Grimsley | Ari | mr | 38 | 2 | 1 | .500 | 0 | .000 | 0 | 23 | 7 | .304 | 25 | 25 | 10 | 21.8 | .615 |
| Kevin Gryboski | Was | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 2 | .667 | 3 | 3 | 0 | 37.3 | .643 |
| Eddie Guardado* |   | cl | 35 | 4 | 2 | .500 | 1 | .250 | 6 | 19 | 6 | .316 | 41 | 41 | 16 | 15.6 | .632 |
| Matt Guerrier | Min | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 25 | 15 | .600 | 42 | 41 | 9 | 36.4 | .616 |
| Jeremy Guthrie | Cle | mr | 27 | 2 | 1 | .500 | 1 | .500 | 0 | 11 | 3 | .273 | 9 | 8 | 6 | 39.1 | .548 |
| Angel Guzman | ChN | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 3 | .750 | 16 | 6 | 4 | 53.3 | .593 |
| Charlie Haeger | ChA | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 4 | 3 | 0 | 57.3 | .546 |
| John Halama* | Bal | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 6 | .600 | 12 | 11 | 3 | 39.5 | .627 |
| Roy Halladay | Tor | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 33 | 1 | 1 | 93.3 | .673 |
| Brad Halsey* | Oak | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 4 | 30 | 9 | .300 | 35 | 28 | 12 | 39.7 | .601 |
| Cole Hamels* | Phi | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 96.8 | .612 |
| Jason Hammel | Tam | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 70.6 | .600 |
| Chris Hammond* | Cin | mr | 40 | 3 | 1 | .333 | 2 | .667 | 1 | 21 | 7 | .333 | 27 | 27 | 12 | 23.0 | .634 |
| Justin Hampson* | Col | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 100.0 | .640 |
| Tim Hamulack* | LAN | mr | 29 | 3 | 1 | .333 | 1 | .333 | 6 | 15 | 6 | .400 | 34 | 34 | 7 | 20.2 | .595 |
| Josh Hancock | StL | mr | 28 | 2 | 2 | 1.000 | 0 | .000 | 3 | 47 | 17 | .362 | 54 | 54 | 17 | 23.6 | .621 |
| Devern Hansack | Bos | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 85.0 | .594 |
| Craig Hansen | Bos | mr | 22 | 2 | 2 | 1.000 | 0 | .000 | 0 | 11 | 3 | .273 | 14 | 14 | 5 | 24.1 | .651 |
| Aaron Harang | Cin | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 91.7 | .663 |
| Rich Harden | Oak | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 97.1 | .573 |
| Dan Haren | Oak | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 88.9 | .663 |
| Travis Harper | Tam | mr | 30 | 4 | 3 | .750 | 1 | .250 | 0 | 27 | 15 | .556 | 30 | 30 | 13 | 25.3 | .632 |
| Chad Harville | Tam | mr | 29 | 3 | 2 | .667 | 1 | .333 | 3 | 36 | 10 | .278 | 28 | 28 | 17 | 24.4 | .591 |
| LaTroy Hawkins | Bal | mr | 33 | 7 | 3 | .429 | 4 | .571 | 15 | 36 | 17 | .472 | 62 | 62 | 17 | 20.0 | .650 |
| Aaron Heilman | NYN | mr | 27 | 15 | 5 | .333 | 8 | .533 | 23 | 49 | 19 | .388 | 94 | 94 | 23 | 16.9 | .629 |
| Rick Helling | Mil | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 10 | 8 | 6 | 39.6 | .631 |
| Ben Hendrickson | Mil | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 75.0 | .529 |
| Mark Hendrickson* |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 95.3 | .598 |
| Sean Henn* | NYA | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 80.0 | .575 |
| Brad Hennessey | SF | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 0 | 15 | 5 | .333 | 36 | 24 | 12 | 49.1 | .598 |
| Clay Hensley | SD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 36 | 7 | 3 | 75.7 | .601 |
| Matt Herges | Flo | mr | 36 | 2 | 1 | .500 | 1 | .500 | 9 | 46 | 26 | .565 | 48 | 48 | 7 | 23.0 | .618 |
| Dustin Hermanson | ChA | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 2 | 2 | 1 | 29.5 | .559 |
| Felix Hernandez | Sea | sp | 20 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 104.0 | .632 |
| Livan Hernandez |   | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 1 | 1 | 84.5 | .620 |
| Orlando Hernandez |   | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 1 | 1 | 93.6 | .618 |
| Roberto Hernandez |   | mr | 41 | 2 | 0 | .000 | 2 | 1.000 | 13 | 26 | 10 | .385 | 61 | 61 | 10 | 21.7 | .620 |
| Runelvys Hernandez | KC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 84.7 | .596 |
| Rich Hill* | ChN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 101.5 | .620 |
| Shawn Hill | Was | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 95.3 | .589 |
| Jason Hirsh | Hou | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 75.1 | .618 |
| James Hoey | Bal | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 5 | .500 | 10 | 10 | 4 | 28.7 | .540 |
| Trevor Hoffman | SD | cl | 38 | 53 | 40 | .755 | 13 | .245 | 1 | 41 | 12 | .293 | 74 | 74 | 65 | 16.3 | .654 |
| J.P. Howell* | Tam | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 83.3 | .616 |
| Bob Howry | ChN | mr | 32 | 6 | 1 | .167 | 3 | .500 | 19 | 37 | 12 | .324 | 88 | 88 | 16 | 18.7 | .654 |
| Jon Huber | Sea | mr | 24 | 0 | 0 | .000 | 0 | .000 | 4 | 10 | 1 | .100 | 14 | 14 | 4 | 23.9 | .609 |
| Luke Hudson | KC | sp | 29 | 1 | 0 | .000 | 0 | .000 | 0 | 16 | 8 | .500 | 32 | 17 | 3 | 54.8 | .616 |
| Tim Hudson | Atl | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 92.5 | .628 |
| Travis Hughes | Was | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 9 | 5 | .556 | 10 | 10 | 1 | 31.1 | .576 |
| Jason Isringhausen | StL | cl | 33 | 34 | 23 | .676 | 11 | .324 | 5 | 29 | 12 | .414 | 56 | 56 | 36 | 21.8 | .546 |
| Edwin Jackson | Tam | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 21 | 7 | .333 | 19 | 18 | 7 | 31.3 | .573 |
| Zach Jackson* | Mil | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 76.1 | .629 |
| Chuck James* | Atl | sp | 24 | 2 | 1 | .500 | 1 | .500 | 0 | 12 | 5 | .417 | 31 | 13 | 5 | 62.0 | .583 |
| Casey Janssen | Tor | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 83.2 | .649 |
| Kevin Jarvis |   | mr | 36 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 1 | .250 | 9 | 5 | 4 | 48.3 | .637 |
| Bobby Jenks | ChA | cl | 25 | 41 | 34 | .829 | 7 | .171 | 1 | 47 | 15 | .319 | 78 | 78 | 67 | 17.8 | .645 |
| Jason Jennings | Col | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.1 | .605 |
| Cesar Jimenez* | Sea | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 37.0 | .595 |
| Ubaldo Jimenez | Col | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 108.0 | .602 |
| Jason Johnson |   | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 72.3 | .629 |
| Jim Johnson | Bal | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 45.0 | .489 |
| Josh Johnson | Flo | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 29 | 5 | 4 | 81.3 | .621 |
| Randy Johnson* | NYA | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 34 | 1 | 1 | 92.7 | .630 |
| Tyler Johnson* | StL | mr | 25 | 12 | 5 | .417 | 5 | .417 | 7 | 34 | 13 | .382 | 49 | 49 | 22 | 14.3 | .569 |
| Greg Jones | LAA | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 4 | .667 | 4 | 4 | 4 | 10.3 | .634 |
| Todd Jones | Det | cl | 38 | 40 | 38 | .950 | 2 | .050 | 2 | 33 | 13 | .394 | 62 | 62 | 50 | 12.3 | .667 |
| Jorge Julio |   | cl | 27 | 23 | 18 | .783 | 5 | .217 | 3 | 31 | 6 | .194 | 53 | 53 | 32 | 20.5 | .590 |
| Steve Karsay | Oak | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 0 | .000 | 8 | 8 | 3 | 26.6 | .601 |
| Jeff Karstens | NYA | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 95.7 | .631 |
| Scott Kazmir* | Tam | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 97.8 | .606 |
| Randy Keisler* | Oak | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 0 | 9 | 5 | .556 | 9 | 9 | 3 | 22.3 | .572 |
| Joe Kennedy* | Oak | mr | 27 | 3 | 2 | .667 | 1 | .333 | 6 | 20 | 4 | .200 | 29 | 29 | 8 | 17.7 | .640 |
| Logan Kensing | Flo | mr | 23 | 5 | 2 | .400 | 3 | .600 | 10 | 27 | 15 | .556 | 41 | 41 | 13 | 19.3 | .590 |
| Bobby Keppel | KC | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 82.2 | .613 |
| Byung-Hyun Kim | Col | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 87.5 | .615 |
| Sun-Woo Kim |   | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 8 | 4 | .500 | 6 | 5 | 2 | 40.7 | .590 |
| Ray King* | Col | mr | 32 | 14 | 6 | .429 | 5 | .357 | 20 | 53 | 15 | .283 | 77 | 77 | 14 | 16.1 | .575 |
| Josh Kinney | StL | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 20 | 6 | .300 | 18 | 18 | 2 | 24.4 | .620 |
| Steve Kline* | SF | mr | 33 | 3 | 1 | .333 | 2 | .667 | 22 | 32 | 10 | .313 | 80 | 80 | 12 | 14.8 | .590 |
| Dan Kolb | Mil | mr | 31 | 8 | 1 | .125 | 5 | .625 | 22 | 61 | 24 | .393 | 89 | 89 | 27 | 16.8 | .598 |
| Shane Komine | Oak | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 72.0 | .563 |
| John Koronka* | Tex | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 79.6 | .631 |
| Hong-Chih Kuo* | LAN | mr | 24 | 1 | 0 | .000 | 0 | .000 | 1 | 29 | 2 | .069 | 29 | 24 | 4 | 38.9 | .620 |
| John Lackey | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.5 | .620 |
| Juan Lara* | Cle | mr | 25 | 1 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 4 | 2 | 10.8 | .558 |
| Brandon League | Tor | mr | 23 | 2 | 1 | .500 | 0 | .000 | 4 | 17 | 4 | .235 | 29 | 29 | 19 | 20.3 | .680 |
| Wilfredo Ledezma* | Det | mr | 25 | 1 | 0 | .000 | 0 | .000 | 2 | 16 | 6 | .375 | 27 | 20 | 6 | 36.5 | .631 |
| Cliff Lee* | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 86.3 | .636 |
| Justin Lehr | Mil | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 3 | .429 | 6 | 6 | 3 | 24.2 | .648 |
| Jon Lester* | Bos | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 87.2 | .589 |
| Colby Lewis | Det | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 1 | 1 | 0 | 31.0 | .548 |
| Brad Lidge | Hou | cl | 29 | 33 | 24 | .727 | 9 | .273 | 3 | 42 | 15 | .357 | 70 | 70 | 46 | 18.8 | .603 |
| Cory Lidle |   | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 85.2 | .615 |
| Jon Lieber | Phi | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 82.3 | .693 |
| Ted Lilly* | Tor | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 88.9 | .592 |
| Jose Lima | NYN | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 52.3 | .622 |
| Scott Linebrink | SD | mr | 29 | 9 | 0 | .000 | 9 | 1.000 | 24 | 49 | 23 | .469 | 82 | 82 | 16 | 17.8 | .638 |
| Francisco Liriano* | Min | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 2 | .143 | 33 | 17 | 5 | 65.4 | .643 |
| Wes Littleton | Tex | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 5 | 17 | 7 | .412 | 27 | 27 | 14 | 24.1 | .597 |
| Esteban Loaiza | Oak | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 94.6 | .636 |
| Kameron Loe | Tex | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 80.9 | .635 |
| Adam Loewen* | Bal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 101.9 | .570 |
| Boone Logan* | ChA | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 2 | .182 | 12 | 12 | 4 | 28.8 | .595 |
| Kyle Lohse |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 7 | .778 | 31 | 12 | 7 | 65.0 | .634 |
| Braden Looper | StL | mr | 31 | 15 | 9 | .600 | 3 | .200 | 23 | 52 | 16 | .308 | 93 | 93 | 26 | 16.9 | .645 |
| Javier Lopez* | Bos | mr | 28 | 5 | 3 | .600 | 1 | .200 | 3 | 3 | 0 | .000 | 21 | 21 | 12 | 19.0 | .584 |
| Rodrigo Lopez | Bal | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 30 | 1 | 1 | 81.3 | .629 |
| Derek Lowe | LAN | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 96.0 | .636 |
| Mark Lowe | Sea | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 4 | .667 | 4 | 4 | 0 | 37.8 | .596 |
| Noah Lowry* | SF | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 87.1 | .614 |
| Ruddy Lugo | Tam | mr | 26 | 13 | 4 | .308 | 8 | .615 | 19 | 61 | 28 | .459 | 80 | 80 | 32 | 21.8 | .596 |
| Brandon Lyon | Ari | mr | 26 | 5 | 3 | .600 | 1 | .200 | 6 | 31 | 9 | .290 | 48 | 48 | 21 | 17.4 | .658 |
| Mike MacDougal |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 3 | 7 | 2 | .286 | 17 | 17 | 6 | 21.2 | .636 |
| Greg Maddux |   | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 86.4 | .664 |
| Ryan Madson | Phi | mr | 25 | 2 | 1 | .500 | 1 | .500 | 0 | 21 | 3 | .143 | 46 | 29 | 10 | 44.4 | .637 |
| Ron Mahay* | Tex | mr | 35 | 6 | 0 | .000 | 5 | .833 | 13 | 24 | 9 | .375 | 57 | 57 | 11 | 19.9 | .582 |
| Paul Maholm* | Pit | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 82.0 | .591 |
| John Maine | NYN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 96.1 | .612 |
| Gary Majewski |   | mr | 26 | 4 | 3 | .750 | 1 | .250 | 3 | 40 | 17 | .425 | 56 | 56 | 19 | 19.0 | .615 |
| Julio Manon | Bal | mr | 32 | 0 | 0 | .000 | 0 | .000 | 2 | 30 | 16 | .533 | 22 | 22 | 2 | 26.7 | .546 |
| Shaun Marcum | Tor | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 1 | 0 | 77.4 | .606 |
| Carlos Marmol | ChN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 22 | 9 | 5 | 61.0 | .545 |
| Mike Maroth* | Det | sp | 28 | 2 | 1 | .500 | 0 | .000 | 1 | 2 | 1 | .500 | 16 | 7 | 2 | 60.3 | .664 |
| Jason Marquis | StL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 73.6 | .619 |
| Sean Marshall* | ChN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 86.0 | .604 |
| Damaso Marte* | Pit | mr | 31 | 7 | 3 | .429 | 4 | .571 | 13 | 29 | 16 | .552 | 65 | 65 | 19 | 18.4 | .573 |
| Tom Martin* | Col | mr | 36 | 4 | 3 | .750 | 1 | .250 | 2 | 32 | 14 | .438 | 47 | 47 | 12 | 25.1 | .613 |
| Carlos Martinez | Flo | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 3 | 0 | .000 | 11 | 11 | 4 | 23.2 | .627 |
| Pedro Martinez | NYN | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 90.3 | .637 |
| Tom Mastny | Cle | cl | 25 | 18 | 10 | .556 | 8 | .444 | 2 | 19 | 3 | .158 | 24 | 24 | 14 | 18.0 | .623 |
| Juan Mateo | ChN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 81.5 | .590 |
| Julio Mateo | Sea | mr | 28 | 3 | 1 | .333 | 2 | .667 | 5 | 27 | 11 | .407 | 38 | 38 | 16 | 19.8 | .624 |
| Scott Mathieson | Phi | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 9 | 1 | 1 | 58.8 | .618 |
| Joe Mays |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 62.8 | .578 |
| Macay McBride* | Atl | mr | 23 | 15 | 4 | .267 | 7 | .467 | 14 | 35 | 13 | .371 | 57 | 57 | 14 | 19.6 | .540 |
| Brandon McCarthy | ChA | mr | 22 | 3 | 2 | .667 | 1 | .333 | 2 | 62 | 18 | .290 | 55 | 53 | 14 | 31.6 | .608 |
| Seth McClung | Tam | mr | 25 | 8 | 5 | .625 | 3 | .375 | 1 | 15 | 8 | .533 | 32 | 17 | 15 | 45.5 | .550 |
| Dustin McGowan | Tor | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 7 | 4 | 1 | 62.3 | .571 |
| Marty McLeary | Pit | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 83.5 | .557 |
| Brian Meadows | Tam | mr | 30 | 8 | 4 | .500 | 3 | .375 | 3 | 68 | 35 | .515 | 65 | 65 | 23 | 26.0 | .668 |
| Gil Meche | Sea | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.0 | .607 |
| Brandon Medders | Ari | mr | 26 | 8 | 4 | .500 | 4 | .500 | 10 | 37 | 13 | .351 | 67 | 67 | 24 | 21.3 | .620 |
| Kent Mercker* | Cin | mr | 38 | 3 | 0 | .000 | 1 | .333 | 8 | 28 | 11 | .393 | 43 | 43 | 10 | 17.1 | .592 |
| Cla Meredith | SD | mr | 23 | 1 | 0 | .000 | 0 | .000 | 0 | 14 | 5 | .357 | 25 | 25 | 9 | 20.3 | .703 |
| Jose Mesa | Col | mr | 40 | 9 | 2 | .222 | 6 | .667 | 28 | 37 | 11 | .297 | 82 | 82 | 23 | 17.7 | .567 |
| Randy Messenger | Flo | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 2 | 25 | 6 | .240 | 28 | 28 | 5 | 22.4 | .639 |
| Dan Miceli | Tam | mr | 35 | 4 | 1 | .250 | 3 | .750 | 1 | 12 | 5 | .417 | 20 | 20 | 12 | 25.6 | .591 |
| Chris Michalak* | Cin | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 0 | 61.9 | .582 |
| Andrew Miller* | Det | mr | 21 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 4 | .500 | 9 | 9 | 0 | 12.1 | .459 |
| Matt Miller | Cle | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 2 | 2 | 0 | 27.0 | .537 |
| Trever Miller* | Hou | mr | 33 | 7 | 4 | .571 | 3 | .429 | 15 | 29 | 7 | .241 | 61 | 61 | 16 | 16.1 | .663 |
| Wade Miller | ChN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 89.6 | .551 |
| Kevin Millwood | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 87.8 | .657 |
| Eric Milton* | Cin | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 89.8 | .636 |
| Zach Miner | Det | sp | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 1 | .250 | 24 | 8 | 5 | 57.2 | .632 |
| Sergio Mitre | Flo | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 14 | 7 | 3 | 60.1 | .591 |
| Brian Moehler | Flo | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 4 | .444 | 29 | 8 | 3 | 66.9 | .622 |
| Agustin Montero | ChA | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 3 | .300 | 9 | 9 | 3 | 26.6 | .632 |
| Juan Morillo | Col | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 94.0 | .532 |
| Matt Morris | SF | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 34 | 1 | 1 | 84.2 | .638 |
| Dustin Moseley | LAA | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 53.5 | .626 |
| Guillermo Mota |   | mr | 32 | 3 | 1 | .333 | 1 | .333 | 2 | 20 | 10 | .500 | 63 | 63 | 32 | 19.6 | .635 |
| Jamie Moyer* |   | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 87.5 | .638 |
| Peter Moylan | Atl | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 10 | 4 | .400 | 15 | 15 | 3 | 25.2 | .677 |
| Edward Mujica | Cle | mr | 22 | 1 | 0 | .000 | 1 | 1.000 | 0 | 1 | 0 | .000 | 8 | 8 | 4 | 31.1 | .791 |
| Mark Mulder* | StL | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 75.9 | .597 |
| Terry Mulholland* | Ari | mr | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 37.0 | .703 |
| Scott Munter | SF | mr | 26 | 2 | 0 | .000 | 1 | .500 | 0 | 13 | 2 | .154 | 18 | 18 | 4 | 20.9 | .549 |
| Mike Mussina | NYA | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 98.3 | .666 |
| Brett Myers | Phi | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 95.5 | .641 |
| Mike Myers* | NYA | mr | 37 | 7 | 3 | .429 | 0 | .000 | 17 | 25 | 9 | .360 | 60 | 60 | 15 | 14.7 | .636 |
| Chris Narveson* | StL | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 95.0 | .526 |
| Joe Nathan | Min | cl | 31 | 38 | 35 | .921 | 3 | .079 | 1 | 41 | 3 | .073 | 61 | 61 | 53 | 20.5 | .689 |
| Jeff Nelson | ChA | mr | 39 | 1 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 5 | 5 | 3 | 19.0 | .558 |
| Joe Nelson | KC | mr | 31 | 17 | 13 | .765 | 4 | .235 | 2 | 35 | 12 | .343 | 37 | 37 | 30 | 16.2 | .596 |
| Pat Neshek | Min | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 1 | .143 | 15 | 15 | 4 | 23.8 | .686 |
| Fernando Nieve | Hou | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 9 | 2 | .222 | 24 | 13 | 4 | 56.2 | .603 |
| Dustin Nippert | Ari | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 50.0 | .600 |
| Ricky Nolasco | Flo | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 25 | 3 | 3 | 86.4 | .624 |
| Roberto Novoa | ChN | mr | 26 | 0 | 0 | .000 | 0 | .000 | 5 | 50 | 22 | .440 | 57 | 57 | 6 | 23.5 | .594 |
| Leo Nunez | KC | mr | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 8 | .889 | 12 | 12 | 5 | 25.0 | .590 |
| Mike O'Connor* | Was | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 86.3 | .593 |
| Eric O'Flaherty* | Sea | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 3 | .333 | 10 | 10 | 2 | 22.2 | .608 |
| Ryan O'Malley* | ChN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 109.0 | .514 |
| Tomo Ohka | Mil | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 95.7 | .599 |
| Will Ohman* | ChN | mr | 28 | 11 | 3 | .273 | 5 | .455 | 16 | 31 | 15 | .484 | 78 | 78 | 20 | 19.0 | .573 |
| Darren Oliver* | NYN | mr | 35 | 6 | 5 | .833 | 1 | .167 | 3 | 44 | 16 | .364 | 55 | 55 | 22 | 26.5 | .629 |
| Scott Olsen* | Flo | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 94.8 | .611 |
| Ramon Ortiz | Was | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 34 | 1 | 1 | 85.1 | .640 |
| Russ Ortiz |   | sp | 32 | 2 | 0 | .000 | 1 | .500 | 2 | 30 | 14 | .467 | 40 | 29 | 7 | 33.9 | .586 |
| Chad Orvella | Tam | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 16 | 10 | .625 | 16 | 16 | 7 | 34.4 | .539 |
| Franquelis Osoria | LAN | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 6 | 3 | .500 | 15 | 15 | 5 | 24.5 | .572 |
| Roy Oswalt | Hou | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.5 | .662 |
| Akinori Otsuka | Tex | cl | 34 | 40 | 35 | .875 | 5 | .125 | 0 | 41 | 12 | .293 | 68 | 68 | 59 | 18.8 | .670 |
| Vicente Padilla | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.0 | .621 |
| Jonathan Papelbon | Bos | cl | 25 | 27 | 23 | .852 | 4 | .148 | 2 | 47 | 14 | .298 | 63 | 63 | 54 | 18.1 | .660 |
| Chan Ho Park | SD | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 81.2 | .629 |
| Chad Paronto | Atl | mr | 30 | 3 | 2 | .667 | 1 | .333 | 9 | 23 | 9 | .391 | 52 | 52 | 20 | 18.5 | .634 |
| John Patterson | Was | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 92.8 | .635 |
| David Pauley | Bos | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 68.7 | .617 |
| Jake Peavy | SD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.8 | .638 |
| Mike Pelfrey | NYN | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 73.8 | .580 |
| Tony Pena | Ari | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 17 | 5 | .294 | 19 | 19 | 1 | 25.9 | .604 |
| Hayden Penn | Bal | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 49.7 | .547 |
| Brad Penny | LAN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 82.8 | .634 |
| Joel Peralta | KC | mr | 30 | 11 | 8 | .727 | 1 | .091 | 8 | 36 | 9 | .250 | 56 | 56 | 21 | 19.4 | .639 |
| Beltran Perez | Was | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 87.3 | .565 |
| Juan Perez* | Pit | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 3 | .500 | 7 | 7 | 1 | 24.7 | .526 |
| Odalis Perez* |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 30 | 10 | 5 | 58.6 | .625 |
| Oliver Perez* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 85.3 | .550 |
| Rafael Perez* | Cle | mr | 24 | 3 | 1 | .333 | 2 | .667 | 8 | 14 | 4 | .286 | 26 | 26 | 6 | 15.5 | .602 |
| Yusmeiro Petit | Flo | mr | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 16 | 9 | .563 | 19 | 18 | 9 | 36.1 | .654 |
| Andy Pettitte* | Hou | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 88.3 | .624 |
| Joel Pineiro | Sea | sp | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 5 | 2 | .400 | 35 | 10 | 8 | 66.2 | .622 |
| Renyel Pinto* | Flo | mr | 23 | 4 | 0 | .000 | 4 | 1.000 | 7 | 15 | 5 | .333 | 29 | 29 | 7 | 21.2 | .539 |
| Cliff Politte | ChA | mr | 32 | 2 | 1 | .500 | 1 | .500 | 0 | 7 | 3 | .429 | 13 | 13 | 7 | 22.0 | .668 |
| Sidney Ponson |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 81.6 | .623 |
| Mark Prior | ChN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 88.0 | .588 |
| Scott Proctor | NYA | mr | 29 | 5 | 2 | .400 | 2 | .400 | 6 | 56 | 16 | .286 | 70 | 70 | 22 | 21.4 | .645 |
| J.J. Putz | Sea | cl | 29 | 36 | 36 | 1.000 | 0 | .000 | 0 | 28 | 6 | .214 | 63 | 63 | 58 | 18.3 | .684 |
| Chad Qualls | Hou | mr | 27 | 7 | 3 | .429 | 4 | .571 | 24 | 34 | 6 | .176 | 86 | 86 | 21 | 16.5 | .621 |
| Brad Radke | Min | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 80.5 | .670 |
| Elizardo Ramirez | Cin | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 75.6 | .638 |
| Horacio Ramirez* | Atl | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 91.1 | .613 |
| Ramon Ramirez | Col | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 4 | 56 | 16 | .286 | 49 | 49 | 9 | 24.8 | .600 |
| Darrell Rasner | NYA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 73.0 | .648 |
| Jon Rauch | Was | mr | 27 | 6 | 2 | .333 | 4 | .667 | 18 | 35 | 16 | .457 | 79 | 79 | 18 | 21.2 | .589 |
| Chris Ray | Bal | cl | 24 | 31 | 26 | .839 | 5 | .161 | 2 | 54 | 18 | .333 | 69 | 69 | 60 | 19.5 | .596 |
| Ken Ray | Atl | mr | 31 | 12 | 6 | .500 | 4 | .333 | 12 | 44 | 14 | .318 | 73 | 73 | 16 | 19.5 | .592 |
| Britt Reames | Pit | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 9 | 9 | 5 | 17.8 | .544 |
| Mark Redman* | KC | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 83.7 | .600 |
| Chris Reitsma | Atl | cl | 28 | 14 | 5 | .357 | 9 | .643 | 4 | 28 | 15 | .536 | 41 | 41 | 19 | 15.0 | .696 |
| Mike Remlinger* | Atl | mr | 40 | 2 | 2 | 1.000 | 0 | .000 | 3 | 18 | 1 | .056 | 25 | 25 | 11 | 16.4 | .564 |
| Chris Resop | Flo | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 7 | 14 | 4 | .286 | 28 | 28 | 5 | 18.5 | .598 |
| Anthony Reyes | StL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 88.8 | .623 |
| Dennys Reyes* | Min | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 15 | 14 | 2 | .143 | 54 | 54 | 8 | 14.6 | .618 |
| John Rheinecker* | Tex | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 15 | 2 | 0 | 79.2 | .625 |
| Arthur Rhodes* | Phi | mr | 36 | 13 | 1 | .077 | 8 | .615 | 16 | 33 | 12 | .364 | 67 | 67 | 17 | 18.8 | .602 |
| Juan Rincon | Min | mr | 27 | 10 | 4 | .400 | 5 | .500 | 23 | 43 | 6 | .140 | 79 | 79 | 24 | 18.4 | .645 |
| Ricardo Rincon* | StL | mr | 36 | 2 | 0 | .000 | 2 | 1.000 | 0 | 9 | 5 | .556 | 5 | 5 | 4 | 23.0 | .557 |
| Royce Ring* | NYN | mr | 25 | 3 | 2 | .667 | 1 | .333 | 1 | 5 | 2 | .400 | 13 | 13 | 8 | 17.1 | .572 |
| David Riske |   | mr | 29 | 4 | 2 | .500 | 2 | .500 | 14 | 29 | 8 | .276 | 54 | 54 | 18 | 19.0 | .601 |
| Mariano Rivera | NYA | cl | 36 | 31 | 28 | .903 | 3 | .097 | 1 | 55 | 13 | .236 | 68 | 68 | 59 | 16.1 | .686 |
| Saul Rivera | Was | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 2 | 55 | 24 | .436 | 51 | 51 | 4 | 21.9 | .591 |
| Sendy Rleal | Bal | mr | 26 | 3 | 1 | .333 | 2 | .667 | 6 | 30 | 13 | .433 | 34 | 34 | 4 | 23.2 | .567 |
| Nate Robertson* | Det | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 97.8 | .639 |
| Fernando Rodney | Det | mr | 29 | 7 | 2 | .286 | 5 | .714 | 11 | 55 | 17 | .309 | 63 | 63 | 14 | 17.5 | .585 |
| Eddy Rodriguez | Bal | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 4 | .667 | 5 | 5 | 4 | 32.8 | .579 |
| Felix Rodriguez | Was | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 12 | 5 | .417 | 16 | 16 | 6 | 25.3 | .562 |
| Francisco Rodriguez | LAA | cl | 24 | 31 | 24 | .774 | 7 | .226 | 2 | 37 | 3 | .081 | 56 | 56 | 46 | 19.5 | .639 |
| Wandy Rodriguez* | Hou | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 1 | 0 | 77.3 | .573 |
| Brian Rogers | Pit | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 3 | .429 | 7 | 7 | 2 | 30.0 | .614 |
| Kenny Rogers* | Det | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 34 | 1 | 0 | 98.4 | .620 |
| Davis Romero* | Tor | mr | 23 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 4 | .800 | 7 | 7 | 1 | 38.1 | .577 |
| J.C. Romero* | LAA | mr | 30 | 10 | 2 | .200 | 5 | .500 | 8 | 17 | 5 | .294 | 43 | 43 | 14 | 19.4 | .600 |
| Francisco Rosario | Tor | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 6 | .750 | 13 | 12 | 4 | 40.8 | .562 |
| Josh Rupe | Tex | mr | 23 | 2 | 1 | .500 | 1 | .500 | 0 | 20 | 7 | .350 | 19 | 19 | 9 | 34.6 | .635 |
| Glendon Rusch* | ChN | mr | 31 | 4 | 4 | 1.000 | 0 | .000 | 0 | 18 | 4 | .222 | 27 | 18 | 10 | 37.5 | .585 |
| B.J. Ryan* | Tor | cl | 30 | 42 | 41 | .976 | 1 | .024 | 0 | 36 | 2 | .056 | 65 | 65 | 60 | 19.7 | .607 |
| Jae Kuk Ryu | ChN | mr | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 6 | 5 | 2 | 28.2 | .698 |
| Kirk Saarloos | Oak | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 20 | 11 | .550 | 35 | 19 | 10 | 55.7 | .593 |
| C.C. Sabathia* | Cle | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 97.3 | .670 |
| Takashi Saito | LAN | cl | 36 | 30 | 26 | .867 | 4 | .133 | 2 | 41 | 10 | .244 | 64 | 64 | 53 | 20.2 | .626 |
| Juan Salas | Tam | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 4 | 4 | 1 | 45.0 | .600 |
| Chris Sampson | Hou | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 0 | .000 | 14 | 11 | 8 | 32.6 | .702 |
| Brian Sanches | Phi | mr | 27 | 5 | 5 | 1.000 | 0 | .000 | 0 | 18 | 4 | .222 | 17 | 17 | 9 | 24.5 | .627 |
| Anibal Sanchez | Flo | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 99.5 | .620 |
| Duaner Sanchez | NYN | mr | 26 | 3 | 2 | .667 | 1 | .333 | 3 | 34 | 10 | .294 | 36 | 36 | 6 | 25.5 | .600 |
| Jonathan Sanchez* | SF | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 1 | .500 | 13 | 9 | 3 | 46.5 | .594 |
| Ervin Santana | LAA | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 91.9 | .631 |
| Johan Santana* | Min | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 99.8 | .667 |
| Julio Santana | Phi | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 15.0 | .533 |
| Victor Santos | Pit | sp | 29 | 3 | 3 | 1.000 | 0 | .000 | 1 | 24 | 9 | .375 | 44 | 25 | 9 | 47.0 | .631 |
| Dennis Sarfate | Mil | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 1 | 4.0 | .750 |
| Scott Sauerbeck* |   | mr | 34 | 6 | 1 | .167 | 3 | .500 | 8 | 22 | 8 | .364 | 35 | 35 | 4 | 19.1 | .543 |
| Joe Saunders* | LAA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 88.2 | .613 |
| Curt Schilling | Bos | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 86.4 | .686 |
| Jason Schmidt | SF | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 103.2 | .630 |
| Scott Schoeneweis* |   | mr | 32 | 3 | 3 | 1.000 | 0 | .000 | 10 | 27 | 9 | .333 | 48 | 48 | 21 | 19.2 | .617 |
| Chris Schroder | Was | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 4 | .400 | 18 | 18 | 6 | 22.9 | .632 |
| Rudy Seanez |   | mr | 37 | 3 | 1 | .333 | 2 | .667 | 6 | 21 | 10 | .476 | 37 | 37 | 10 | 25.0 | .613 |
| Bobby Seay* | Det | mr | 28 | 1 | 0 | .000 | 0 | .000 | 2 | 18 | 6 | .333 | 18 | 18 | 6 | 18.0 | .633 |
| Aaron Sele | LAN | sp | 36 | 2 | 2 | 1.000 | 0 | .000 | 0 | 15 | 8 | .533 | 29 | 14 | 8 | 58.2 | .624 |
| Jae Seo |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 30 | 4 | 3 | 72.4 | .618 |
| Brian Shackelford* | Cin | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 1 | 8 | 5 | .625 | 16 | 16 | 6 | 22.1 | .569 |
| Josh Sharpless | Pit | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 3 | .333 | 13 | 13 | 2 | 26.2 | .543 |
| Ben Sheets | Mil | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 96.3 | .693 |
| George Sherrill* | Sea | mr | 29 | 5 | 1 | .200 | 3 | .600 | 14 | 34 | 9 | .265 | 59 | 59 | 12 | 17.8 | .557 |
| James Shields | Tam | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 88.0 | .623 |
| Scot Shields | LAA | mr | 30 | 7 | 4 | .571 | 3 | .429 | 16 | 44 | 11 | .250 | 68 | 68 | 27 | 20.7 | .649 |
| Jason Shiell | Atl | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 54.7 | .585 |
| Brian Shouse* |   | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 20 | 44 | 16 | .364 | 59 | 59 | 20 | 14.3 | .614 |
| Brian Sikorski |   | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 12 | 7 | .583 | 11 | 11 | 2 | 30.2 | .666 |
| Carlos Silva | Min | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 4 | .400 | 37 | 6 | 2 | 62.3 | .674 |
| Andrew Sisco* | KC | mr | 23 | 6 | 2 | .333 | 2 | .333 | 11 | 28 | 12 | .429 | 56 | 56 | 20 | 19.5 | .589 |
| Doug Slaten* | Ari | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 4 | 4 | 1 | 15.0 | .683 |
| Brian Slocum | Cle | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 3 | 1 | 0 | 55.0 | .576 |
| Aaron Small | NYA | mr | 34 | 1 | 0 | .000 | 1 | 1.000 | 2 | 10 | 5 | .500 | 10 | 7 | 1 | 29.6 | .588 |
| Matt Smith* |   | mr | 27 | 3 | 2 | .667 | 1 | .333 | 4 | 6 | 4 | .667 | 20 | 20 | 10 | 24.4 | .629 |
| Mike Smith | Min | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 50.0 | .560 |
| Travis Smith | Atl | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 39.0 | .436 |
| John Smoltz | Atl | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 96.9 | .652 |
| Ian Snell | Pit | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 85.8 | .623 |
| Kyle Snyder |   | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 3 | .600 | 17 | 6 | 2 | 67.7 | .626 |
| Alay Soler | NYN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 84.9 | .585 |
| Rafael Soriano | Sea | mr | 26 | 3 | 1 | .333 | 0 | .000 | 18 | 41 | 10 | .244 | 62 | 62 | 17 | 18.1 | .611 |
| Jorge Sosa |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 27 | 7 | .259 | 44 | 31 | 13 | 42.8 | .628 |
| Jeremy Sowers* | Cle | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 96.8 | .658 |
| Justin Speier | Tor | mr | 32 | 5 | 1 | .200 | 1 | .200 | 24 | 32 | 8 | .250 | 67 | 67 | 10 | 19.6 | .644 |
| Russ Springer | Hou | mr | 37 | 1 | 0 | .000 | 1 | 1.000 | 1 | 37 | 15 | .405 | 52 | 52 | 12 | 23.4 | .625 |
| Chris Spurling |   | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 9 | 3 | .333 | 12 | 12 | 9 | 17.0 | .623 |
| Jason Standridge | Cin | mr | 27 | 1 | 0 | .000 | 0 | .000 | 3 | 16 | 4 | .250 | 23 | 23 | 3 | 21.4 | .542 |
| Mike Stanton* |   | cl | 39 | 23 | 16 | .696 | 7 | .304 | 13 | 48 | 14 | .292 | 75 | 75 | 34 | 17.8 | .627 |
| Tim Stauffer | SD | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 101.0 | .653 |
| Steve Stemle | KC | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 4 | 1.000 | 4 | 4 | 0 | 49.0 | .546 |
| Brian Stokes | Tam | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 72.0 | .608 |
| Huston Street | Oak | cl | 22 | 40 | 33 | .825 | 7 | .175 | 0 | 40 | 12 | .300 | 66 | 66 | 58 | 18.3 | .675 |
| Eric Stults* | LAN | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 91.0 | .643 |
| Tanyon Sturtze | NYA | mr | 35 | 0 | 0 | .000 | 0 | .000 | 2 | 3 | 0 | .000 | 7 | 7 | 2 | 22.3 | .583 |
| Jeff Suppan | StL | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 88.0 | .625 |
| Brian Sweeney | SD | mr | 32 | 4 | 2 | .500 | 2 | .500 | 0 | 20 | 9 | .450 | 36 | 36 | 17 | 24.5 | .598 |
| Jon Switzer* | Tam | mr | 26 | 8 | 2 | .250 | 4 | .500 | 6 | 23 | 7 | .304 | 34 | 34 | 8 | 19.1 | .583 |
| Brian Tallet* | Tor | mr | 28 | 2 | 0 | .000 | 0 | .000 | 2 | 32 | 12 | .375 | 29 | 28 | 2 | 27.9 | .595 |
| Taylor Tankersley* | Flo | mr | 23 | 4 | 2 | .500 | 2 | .500 | 18 | 34 | 11 | .324 | 54 | 54 | 17 | 18.9 | .568 |
| Jack Taschner* | SF | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 10 | 10 | 1 | 24.0 | .625 |
| Jordan Tata | Det | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 16 | 16 | 5 | 23.4 | .600 |
| Ty Taubenheim | Tor | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 9 | 2 | 1 | 61.9 | .591 |
| Julian Tavarez | Bos | mr | 33 | 2 | 0 | .000 | 2 | 1.000 | 2 | 53 | 19 | .358 | 59 | 53 | 12 | 33.0 | .598 |
| Robinson Tejeda | Tex | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 85.1 | .593 |
| Brad Thompson | StL | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 1 | .167 | 25 | 24 | 8 | 28.2 | .593 |
| Mike Thompson | SD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 81.5 | .625 |
| John Thomson | Atl | sp | 32 | 1 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 16 | 1 | 0 | 83.9 | .631 |
| Matt Thornton* | ChA | mr | 29 | 7 | 4 | .571 | 3 | .429 | 8 | 33 | 11 | .333 | 54 | 54 | 24 | 19.3 | .631 |
| Mike Timlin | Bos | mr | 40 | 11 | 3 | .273 | 6 | .545 | 18 | 49 | 13 | .265 | 79 | 79 | 19 | 17.4 | .683 |
| Brett Tomko | LAN | mr | 33 | 0 | 0 | .000 | 0 | .000 | 2 | 27 | 9 | .333 | 36 | 21 | 4 | 53.3 | .652 |
| Salomon Torres | Pit | mr | 34 | 10 | 2 | .200 | 6 | .600 | 10 | 38 | 12 | .316 | 79 | 79 | 24 | 17.6 | .619 |
| Josh Towers | Tor | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 66.1 | .654 |
| Billy Traber* | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 3 | .500 | 15 | 7 | 0 | 46.1 | .614 |
| Sean Tracey | ChA | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 1 | 5 | 4 | .800 | 7 | 7 | 2 | 22.9 | .544 |
| Steve Trachsel | NYN | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 76.9 | .599 |
| Derrick Turnbow | Mil | cl | 28 | 32 | 19 | .594 | 11 | .344 | 2 | 30 | 15 | .500 | 54 | 54 | 32 | 19.0 | .575 |
| Jose Valverde | Ari | cl | 26 | 15 | 11 | .733 | 4 | .267 | 0 | 8 | 2 | .250 | 31 | 31 | 18 | 21.6 | .594 |
| Jermaine Van Buren | Bos | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 0 | 4 | 2 | .500 | 10 | 10 | 4 | 32.3 | .502 |
| Claudio Vargas | Ari | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 84.6 | .626 |
| Jason Vargas* | Flo | mr | 23 | 2 | 1 | .500 | 1 | .500 | 0 | 8 | 4 | .500 | 14 | 9 | 7 | 48.0 | .580 |
| Javier Vazquez | ChA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.0 | .638 |
| Mike Venafro* | Col | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 3 | 0 | 21.3 | .578 |
| Jose Veras | NYA | mr | 25 | 2 | 2 | 1.000 | 0 | .000 | 4 | 10 | 2 | .200 | 19 | 19 | 11 | 20.6 | .559 |
| Justin Verlander | Det | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 94.8 | .626 |
| Carlos Villanueva | Mil | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 86.2 | .681 |
| Oscar Villarreal | Atl | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 69 | 26 | .377 | 58 | 54 | 8 | 31.3 | .648 |
| Ron Villone* | NYA | mr | 36 | 3 | 1 | .333 | 2 | .667 | 3 | 54 | 18 | .333 | 46 | 46 | 14 | 28.9 | .585 |
| Luis Vizcaino | Ari | mr | 31 | 4 | 2 | .500 | 1 | .250 | 18 | 38 | 8 | .211 | 69 | 69 | 19 | 20.9 | .623 |
| Ryan Vogelsong | Pit | mr | 28 | 4 | 3 | .750 | 1 | .250 | 0 | 21 | 6 | .286 | 28 | 28 | 12 | 35.4 | .563 |
| Edinson Volquez | Tex | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 74.3 | .618 |
| Doug Waechter | Tam | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 87.5 | .633 |
| Billy Wagner* | NYN | cl | 34 | 35 | 28 | .800 | 7 | .200 | 2 | 45 | 14 | .311 | 77 | 77 | 59 | 19.5 | .634 |
| Ryan Wagner | Was | mr | 23 | 1 | 0 | .000 | 1 | 1.000 | 1 | 20 | 10 | .500 | 23 | 23 | 6 | 25.7 | .584 |
| Adam Wainwright | StL | mr | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 39 | 17 | .436 | 54 | 54 | 4 | 25.4 | .629 |
| Tim Wakefield | Bos | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 24 | 1 | 1 | 85.0 | .606 |
| Jamie Walker* | Det | mr | 34 | 4 | 1 | .250 | 2 | .500 | 18 | 58 | 12 | .207 | 69 | 69 | 6 | 11.5 | .665 |
| Pete Walker | Tor | mr | 37 | 2 | 0 | .000 | 1 | .500 | 0 | 26 | 14 | .538 | 29 | 29 | 5 | 30.5 | .606 |
| Tyler Walker |   | mr | 30 | 9 | 9 | 1.000 | 0 | .000 | 0 | 15 | 5 | .333 | 25 | 25 | 20 | 19.1 | .625 |
| Les Walrond* | ChN | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 3 | .375 | 10 | 8 | 0 | 38.4 | .594 |
| Chien-Ming Wang | NYA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.8 | .632 |
| John Wasdin | Tex | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 98.6 | .617 |
| Jarrod Washburn* | Sea | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 88.1 | .625 |
| David Weathers | Cin | mr | 36 | 33 | 27 | .818 | 6 | .182 | 8 | 48 | 15 | .313 | 73 | 73 | 52 | 16.5 | .627 |
| Jeff Weaver |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 82.1 | .642 |
| Jered Weaver | LAA | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 94.7 | .621 |
| Brandon Webb | Ari | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 98.7 | .658 |
| Todd Wellemeyer |   | mr | 27 | 2 | 1 | .500 | 0 | .000 | 2 | 43 | 19 | .442 | 52 | 52 | 15 | 33.0 | .546 |
| David Wells* |   | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 85.7 | .675 |
| Kip Wells |   | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 2 | 1.000 | 10 | 1 | 1 | 57.2 | .614 |
| Jake Westbrook | Cle | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 95.3 | .646 |
| Dan Wheeler | Hou | mr | 28 | 10 | 7 | .700 | 3 | .300 | 12 | 26 | 8 | .308 | 65 | 65 | 29 | 18.6 | .619 |
| Rick White |   | mr | 37 | 10 | 2 | .200 | 5 | .500 | 9 | 30 | 12 | .400 | 64 | 64 | 16 | 19.5 | .622 |
| Bob Wickman |   | cl | 37 | 38 | 30 | .789 | 8 | .211 | 1 | 47 | 14 | .298 | 60 | 60 | 52 | 16.4 | .655 |
| Dave Williams* |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 82.7 | .631 |
| Jerome Williams | ChN | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 1 | 1 | 72.0 | .579 |
| Todd Williams | Bal | mr | 35 | 13 | 6 | .462 | 5 | .385 | 25 | 37 | 15 | .405 | 74 | 74 | 16 | 17.1 | .634 |
| Woody Williams | SD | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 85.8 | .650 |
| Scott Williamson |   | mr | 30 | 3 | 1 | .333 | 2 | .667 | 4 | 18 | 6 | .333 | 44 | 44 | 17 | 21.7 | .595 |
| Dontrelle Willis* | Flo | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 102.8 | .603 |
| Brian Wilson | SF | mr | 24 | 8 | 3 | .375 | 5 | .625 | 11 | 20 | 9 | .450 | 43 | 43 | 10 | 17.9 | .577 |
| C.J. Wilson* | Tex | mr | 25 | 2 | 1 | .500 | 1 | .500 | 4 | 18 | 2 | .111 | 30 | 30 | 12 | 18.0 | .614 |
| Kris Wilson | NYA | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 34.0 | .618 |
| Jason Windsor | Oak | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 58.7 | .591 |
| Joe Winkelsas | Mil | mr | 32 | 1 | 1 | 1.000 | 0 | .000 | 0 | 9 | 5 | .556 | 8 | 8 | 4 | 24.8 | .535 |
| Matt Wise | Mil | mr | 30 | 12 | 6 | .500 | 5 | .417 | 6 | 29 | 8 | .276 | 43 | 43 | 23 | 18.2 | .630 |
| Jay Witasick | Oak | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 16 | 9 | .563 | 11 | 11 | 1 | 40.5 | .519 |
| Randy Wolf* | Phi | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 64.7 | .590 |
| Kerry Wood | ChN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 70.8 | .611 |
| Mike Wood | KC | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 27 | 13 | .481 | 35 | 28 | 8 | 41.1 | .642 |
| Jake Woods* | Sea | mr | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 40 | 14 | .350 | 46 | 38 | 14 | 43.8 | .593 |
| Tim Worrell | SF | cl | 38 | 6 | 5 | .833 | 1 | .167 | 0 | 22 | 6 | .273 | 22 | 22 | 15 | 14.8 | .617 |
| Jamey Wright | SF | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 33 | 12 | 2 | 63.3 | .614 |
| Jaret Wright | NYA | sp | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 28 | 1 | 1 | 80.7 | .610 |
| Michael Wuertz | ChN | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 4 | .364 | 16 | 16 | 5 | 22.4 | .630 |
| Esteban Yan |   | mr | 31 | 1 | 0 | .000 | 0 | .000 | 0 | 29 | 14 | .483 | 29 | 29 | 10 | 27.9 | .580 |
| Tyler Yates | Atl | mr | 28 | 9 | 4 | .444 | 4 | .444 | 2 | 41 | 12 | .293 | 36 | 36 | 11 | 23.1 | .606 |
| Shane Youman* | Pit | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 90.3 | .550 |
| Chris Young | SD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 93.2 | .618 |
| Carlos Zambrano | ChN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 106.3 | .587 |
| Victor Zambrano | NYN | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 81.8 | .548 |
| Barry Zito* | Oak | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 101.0 | .607 |
| Joel Zumaya | Det | mr | 21 | 11 | 3 | .273 | 8 | .727 | 17 | 46 | 12 | .261 | 70 | 70 | 18 | 17.6 | .607 |